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Search results 301 to 368 out of 368 for Atp7b

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4427735
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823342
Age: embryonic day 14.5
Image: euxassay_018905_15
Specimen Label: euxassay_018905_15
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:4427735
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823342
Age: embryonic day 14.5
Image: euxassay_018905_17
Specimen Label: euxassay_018905_17
Detected: true
Specimen Num: 17
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Publication
22308360 | J:182626
First Author: Hirayama T
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Near-infrared fluorescent sensor for in vivo copper imaging in a murine Wilson disease model.
Volume: 109
Issue: 7
Pages: 2228-33
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Publication
9020864 | J:38135
 
First Author: Grimes A
Year: 1997
Journal: Biochem J
Title: Decreased carbonic anhydrase III levels in the liver of the mouse mutant 'toxic milk' (tx) due to copper accumulation.
Volume: 321 ( Pt 2)
Pages: 341-6
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Publication
1588441 | J:1046
First Author: Mercer JF
Year: 1992
Journal: J Nutr
Title: Hepatic metallothionein gene expression in toxic milk mice.
Volume: 122
Issue: 6
Pages: 1254-9
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Publication
17910951 | J:127349
First Author: Roberts EA
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Developmental expression of Commd1 in the liver of the Jackson toxic milk mouse.
Volume: 363
Issue: 4
Pages: 921-5
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Publication
8082762 | J:20585
First Author: Paynter JA
Year: 1994
Journal: FEBS Lett
Title: Expression of the Menkes gene homologue in mouse tissues lack of effect of copper on the mRNA levels.
Volume: 351
Issue: 2
Pages: 186-90
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Publication
33462188 | J:330281
First Author: Dong J
Year: 2021
Journal: Cell Death Dis
Title: Inhibiting NLRP3 inflammasome activation prevents copper-induced neuropathology in a murine model of Wilson's disease.
Volume: 12
Issue: 1
Pages: 87
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Publication
8732640 | J:33670
First Author: Tümer Z
Year: 1996
Journal: Ann Med
Title: Menkes disease: recent advances and new insights into copper metabolism.
Volume: 28
Issue: 2
Pages: 121-9
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Publication
9215673 | J:41389
First Author: Kuo YM
Year: 1997
Journal: Hum Mol Genet
Title: Developmental expression of the mouse mottled and toxic milk genes suggests distinct functions for the Menkes and Wilson disease copper transporters.
Volume: 6
Issue: 7
Pages: 1043-9
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Publication
9823011 | J:51197
First Author: Harris ED
Year: 1998
Journal: Mol Cell Biochem
Title: Genes regulating copper metabolism.
Volume: 188
Issue: 1-2
Pages: 57-62
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Publication
9392450 | J:44523
First Author: Ono S
Year: 1997
Journal: Toxicology
Title: Regional brain distribution of metallothionein, zinc and copper in toxic milk mutant and transgenic mice.
Volume: 124
Issue: 1
Pages: 1-10
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Publication
26241054 | J:226266
First Author: Wooton-Kee CR
Year: 2015
Journal: J Clin Invest
Title: Elevated copper impairs hepatic nuclear receptor function in Wilson's disease.
Volume: 125
Issue: 9
Pages: 3449-60
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Publication
8921375 | J:35799
First Author: Cecchi C
Year: 1996
Journal: Genomics
Title: Genomic organization of the mottled gene, the mouse homologue of the human Menkes disease gene.
Volume: 37
Issue: 1
Pages: 96-104
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Publication
12644567 | J:82526
First Author: Morrison GM
Year: 2003
Journal: Mol Biol Evol
Title: Signal sequence conservation and mature peptide divergence within subgroups of the murine beta-defensin gene family.
Volume: 20
Issue: 3
Pages: 460-70
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Publication
16785251 | J:112037
First Author: Sebastiani G
Year: 2006
Journal: Hum Mol Genet
Title: Mapping genetic modulators of amyloid plaque deposition in TgCRND8 transgenic mice.
Volume: 15
Issue: 15
Pages: 2313-23
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
20005242 | J:227897
First Author: Ibricevic A
Year: 2010
Journal: Toxicol Appl Pharmacol
Title: ATP7B detoxifies silver in ciliated airway epithelial cells.
Volume: 243
Issue: 3
Pages: 315-22
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Publication
10856972 | J:63005
First Author: Ogiu T
Year: 2000
Journal: Radiat Res
Title: Absence of linkage between radiosensitivity and the predisposing atp7b gene mutation for heritable hepatitis in the LEC rat.
Volume: 154
Issue: 1
Pages: 113-6
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Publication
16554302 | -
First Author: Lim CM
Year: 2006
Journal: J Biol Chem
Title: Copper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7A.
Volume: 281
Issue: 20
Pages: 14006-14
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Allele
Atp7b<em1Smoc> | MGI:7288398
Name: ATPase, Cu++ transporting, beta polypeptide; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Strain
MGI:6354555 | C57BL/6J-Atp7b<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
8782057 | -
First Author: Chuang LM
Year: 1996
Journal: J Med Genet
Title: High frequency of two mutations in codon 778 in exon 8 of the ATP7B gene in Taiwanese families with Wilson disease.
Volume: 33
Issue: 6
Pages: 521-3
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Protein
Q8CBY8
Organism: Mus musculus/domesticus
Length: 467  
Fragment?: false
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Protein
Q3TQY2
Organism: Mus musculus/domesticus
Length: 460  
Fragment?: false
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Protein
Q9CRP9
Organism: Mus musculus/domesticus
Length: 63  
Fragment?: true
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Publication
10607597 | -
First Author: Garces JA
Year: 1999
Journal: Curr Biol
Title: Interaction of the p62 subunit of dynactin with Arp1 and the cortical actin cytoskeleton.
Volume: 9
Issue: 24
Pages: 1497-500
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Protein Domain
IPR008603 | DCTN4
Type: Family
Description: DCTN4 (also known as dynactin subunit p62) is a subunit of the dynactin that may have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. It could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton []. It also interacts with the N terminus of P-type ATPase ATP7B [].
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Publication
10079817 | -
 
First Author: Tümer Z
Year: 1999
Journal: Adv Exp Med Biol
Title: Mutation spectrum of ATP7A, the gene defective in Menkes disease.
Volume: 448
Pages: 83-95
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Publication
10319818 | -
First Author: Hirayama T
Year: 1999
Journal: Cell
Title: RESPONSIVE-TO-ANTAGONIST1, a Menkes/Wilson disease-related copper transporter, is required for ethylene signaling in Arabidopsis.
Volume: 97
Issue: 3
Pages: 383-93
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Protein Domain
IPR027256 | P-typ_ATPase_IB
Type: Family
Description: P-ATPases (also known as E1-E2 ATPases) ([intenz:3.6.3.-]) are found in bacteria and in a number of eukaryotic plasma membranes and organelles []. P-ATPases function to transport a variety of different compounds, including ions and phospholipids, across a membrane using ATP hydrolysis for energy. There are many different classes of P-ATPases, which transport specific types of ion: H+, Na+, K+, Mg2+, Ca2+, Ag+and Ag2+, Zn2+, Co2+, Pb2+, Ni2+, Cd2+, Cu+and Cu2+. P-ATPases can be composed of one or two polypeptides, and can usually assume two main conformations called E1 and E2.This entry represents the copper and cadmium-type heavy metal transporting P-type ATPases, and other related sequences that belong to the IB subfamily of P-type ATPases. Type IB ATPases are involved in transport of the soft Lewis acids: Cu+, Ag+, Cu2+, Zn2+, Cd2+, Pb2+and Co2+. These proteins are involved in a variety of processes in both prokaryotes and eukaryotes. In Arabidopsis, the copper-ATPase RAN1 delivers copper to create functional hormone receptors involved in ethylene signalling []. In humans, ATP7A supplies copper to copper-dependent enzymes in the secretory pathway, while ATP7B exports copper out of the cells. Defects in ATP7B are the cause of Wilson disease (WD), an autosomal recessive disorder in which copper cannot be incorporated into ceruloplasmin in liver and cannot be excreted from the liver into the bile []. Defects in ATP7A are the cause of Menkes disease (MNKD), also known as kinky hair disease. MNKD is an X-linked recessive disorder of copper metabolism characterised by generalised copper deficiency [].
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Publication
18515074 | J:137792
First Author: Llanos RM
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Copper transport during lactation in transgenic mice expressing the human ATP7A protein.
Volume: 372
Issue: 4
Pages: 613-7
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Publication
18650808 | J:139015
First Author: Setty SR
Year: 2008
Journal: Nature
Title: Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes.
Volume: 454
Issue: 7208
Pages: 1142-6
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Publication
33262129 | J:299619
     
First Author: Singla A
Year: 2020
Journal: Dis Model Mech
Title: Regulation of copper homeostasis by members of the COMMD protein family.
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Publication
9949209 | J:53371
First Author: van de Sluis BJ
Year: 1999
Journal: Hum Mol Genet
Title: Genetic mapping of the copper toxicosis locus in Bedlington terriers to dog chromosome 10, in a region syntenic to human chromosome region 2p13-p16.
Volume: 8
Issue: 3
Pages: 501-7
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Publication
30997485 | J:276794
First Author: Ogórek M
Year: 2019
Journal: Biol Reprod
Title: Molecular machinery providing copper bioavailability for spermatozoa along the epididymial tubule in mouse.
Volume: 100
Issue: 6
Pages: 1505-1520
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Publication
22216203 | J:182331
First Author: Vonk WI
Year: 2011
Journal: PLoS One
Title: Liver-specific Commd1 knockout mice are susceptible to hepatic copper accumulation.
Volume: 6
Issue: 12
Pages: e29183
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Protein
Q64446
Organism: Mus musculus/domesticus
Length: 1462  
Fragment?: false
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Protein
Q64430
Organism: Mus musculus/domesticus
Length: 1491  
Fragment?: false
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Protein
B1AQ57
Organism: Mus musculus/domesticus
Length: 1347  
Fragment?: false
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Protein
A2AG68
Organism: Mus musculus/domesticus
Length: 1492  
Fragment?: false
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Protein
B9EJ97
Organism: Mus musculus/domesticus
Length: 1492  
Fragment?: false
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Publication
9419228 | J:44815
First Author: Axelsen KB
Year: 1998
Journal: J Mol Evol
Title: Evolution of substrate specificities in the P-type ATPase superfamily.
Volume: 46
Issue: 1
Pages: 84-101
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