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Search results 1 to 1 out of 1 for E2f5

Category restricted to ProteinDomain (x)

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Category: ProteinDomain
Type Details Score
Protein Domain
Type: Family
Description: E2F5 is a transcription activator that binds cooperatively with DP1 to E2F sites, which are present in the promoter of many genes whose products are involved in cell proliferation []. E2F5 is a component of the DREAM (MuvB/DRM) complex, which represses cell cycle-dependent genes in quiescent cells and plays a role in the cell cycle-dependent activation of G2/M genes [, ].