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Search results 1 to 98 out of 98 for Hcar2

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Category: Publication
Type Details Score
Publication
First Author: Soga T
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Molecular identification of nicotinic acid receptor.
Volume: 303
Issue: 1
Pages: 364-9
Publication
First Author: Tunaru S
Year: 2003
Journal: Nat Med
Title: PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect.
Volume: 9
Issue: 3
Pages: 352-5
Publication
First Author: Liu C
Year: 2009
Journal: J Biol Chem
Title: Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81.
Volume: 284
Issue: 5
Pages: 2811-22
Publication
First Author: Boccella S
Year: 2019
Journal: FASEB J
Title: Ketones and pain: unexplored role of hydroxyl carboxylic acid receptor type 2 in the pathophysiology of neuropathic pain.
Volume: 33
Issue: 1
Pages: 1062-1073
Publication  
First Author: Parodi B
Year: 2021
Journal: Front Immunol
Title: Hydroxycarboxylic Acid Receptor 2, a Pleiotropically Linked Receptor for the Multiple Sclerosis Drug, Monomethyl Fumarate. Possible Implications for the Inflammatory Response.
Volume: 12
Pages: 655212
Publication
First Author: Dmitrieva-Posocco O
Year: 2022
Journal: Nature
Title: β-Hydroxybutyrate suppresses colorectal cancer.
Volume: 605
Issue: 7908
Pages: 160-165
Publication
First Author: Schaub A
Year: 2001
Journal: Eur J Immunol
Title: PUMA-G, an IFN-gamma-inducible gene in macrophages is a novel member of the seven transmembrane spanning receptor superfamily.
Volume: 31
Issue: 12
Pages: 3714-25
Publication
First Author: Elangovan S
Year: 2014
Journal: Cancer Res
Title: The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival.
Volume: 74
Issue: 4
Pages: 1166-78
Publication
First Author: Wu Y
Year: 2020
Journal: FASEB J
Title: BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease.
Volume: 34
Issue: 1
Pages: 1412-1429
Publication
First Author: Benyó Z
Year: 2005
Journal: J Clin Invest
Title: GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing.
Volume: 115
Issue: 12
Pages: 3634-40
Publication
First Author: Ni D
Year: 2023
Journal: Eur J Immunol
Title: GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development.
Volume: 53
Issue: 11
Pages: e2350521
Publication
First Author: Hepler C
Year: 2016
Journal: Am J Physiol Regul Integr Comp Physiol
Title: The hypophagic response to heat stress is not mediated by GPR109A or peripheral β-OH butyrate.
Volume: 310
Issue: 10
Pages: R992-8
Publication
First Author: Takakura A
Year: 2019
Journal: FASEB J
Title: Lactate-induced activation of HCA2 improves survival in mice with sepsis.
Volume: 33
Issue: 6
Pages: 7625-7634
Publication
First Author: Li X
Year: 2010
Journal: Biochem Pharmacol
Title: Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.
Volume: 80
Issue: 9
Pages: 1450-7
Publication
First Author: Ye L
Year: 2020
Journal: J Nutr
Title: Niacin Ameliorates Hepatic Steatosis by Inhibiting De Novo Lipogenesis Via a GPR109A-Mediated PKC-ERK1/2-AMPK Signaling Pathway in C57BL/6 Mice Fed a High-Fat Diet.
Volume: 150
Issue: 4
Pages: 672-684
Publication
First Author: Snelson M
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Exploring the role of the metabolite-sensing receptor GPR109a in diabetic nephropathy.
Volume: 318
Issue: 3
Pages: F835-F842
Publication
First Author: Wanders D
Year: 2013
Journal: PLoS One
Title: Niacin increases adiponectin and decreases adipose tissue inflammation in high fat diet-fed mice.
Volume: 8
Issue: 8
Pages: e71285
Publication
First Author: Zandi-Nejad K
Year: 2013
Journal: FASEB J
Title: The role of HCA2 (GPR109A) in regulating macrophage function.
Volume: 27
Issue: 11
Pages: 4366-74
Publication  
First Author: Schwarz A
Year: 2023
Journal: Front Immunol
Title: Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model.
Volume: 14
Pages: 1038689
Publication
First Author: Felizardo RJF
Year: 2019
Journal: FASEB J
Title: Gut microbial metabolite butyrate protects against proteinuric kidney disease through epigenetic- and GPR109a-mediated mechanisms.
Volume: 33
Issue: 11
Pages: 11894-11908
Publication  
First Author: Geisler CE
Year: 2021
Journal: Int J Mol Sci
Title: The Role of GPR109a Signaling in Niacin Induced Effects on Fed and Fasted Hepatic Metabolism.
Volume: 22
Issue: 8
Publication
First Author: Ye L
Year: 2019
Journal: FASEB J
Title: Niacin fine-tunes energy homeostasis through canonical GPR109A signaling.
Volume: 33
Issue: 4
Pages: 4765-4779
Publication  
First Author: Gong Y
Year: 2020
Journal: Front Immunol
Title: G Protein-Coupled Receptor 109A Maintains the Intestinal Integrity and Protects Against ETEC Mucosal Infection by Promoting IgA Secretion.
Volume: 11
Pages: 583652
Publication
First Author: Chen H
Year: 2014
Journal: J Clin Invest
Title: Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE.
Volume: 124
Issue: 5
Pages: 2188-92
Publication
First Author: Docampo MD
Year: 2022
Journal: Blood
Title: Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease.
Volume: 139
Issue: 15
Pages: 2392-2405
Publication  
First Author: Chen G
Year: 2018
Journal: Front Immunol
Title: G Protein-Coupled Receptor 109A and Host Microbiota Modulate Intestinal Epithelial Integrity During Sepsis.
Volume: 9
Pages: 2079
Publication
First Author: Jadeja RN
Year: 2019
Journal: Aging (Albany NY)
Title: Loss of GPR109A/HCAR2 induces aging-associated hepatic steatosis.
Volume: 11
Issue: 2
Pages: 386-400
Publication
First Author: Chen JR
Year: 2021
Journal: Commun Biol
Title: GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice.
Volume: 4
Issue: 1
Pages: 53
Publication  
First Author: Chen JR
Year: 2022
Journal: Bone
Title: GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice.
Volume: 161
Pages: 116422
Publication  
First Author: Wannick M
Year: 2018
Journal: Front Immunol
Title: The Immunometabolomic Interface Receptor Hydroxycarboxylic Acid Receptor 2 Mediates the Therapeutic Effects of Dimethyl Fumarate in Autoantibody-Induced Skin Inflammation.
Volume: 9
Pages: 1890
Publication
First Author: Subramani K
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock.
Volume: 1865
Issue: 3
Pages: 688-695
Publication  
First Author: Shi Y
Year: 2017
Journal: Sci Rep
Title: Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization.
Volume: 7
Pages: 42279
Publication    
First Author: Schaub A
Year: 2000
Journal: GenBank Submission
Title: Mus musculus mRNA for putative seven transmembrane spanning receptor (Puma-g gene)
Pages: AJ300198
Publication  
First Author: Rahman M
Year: 2014
Journal: Nat Commun
Title: The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages.
Volume: 5
Pages: 3944
Publication
First Author: Horimatsu T
Year: 2020
Journal: Cardiovasc Res
Title: Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide.
Volume: 116
Issue: 14
Pages: 2226-2238
Publication
First Author: Lukasova M
Year: 2011
Journal: J Clin Invest
Title: Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells.
Volume: 121
Issue: 3
Pages: 1163-73
Publication
First Author: Lauring B
Year: 2012
Journal: Sci Transl Med
Title: Niacin lipid efficacy is independent of both the niacin receptor GPR109A and free fatty acid suppression.
Volume: 4
Issue: 148
Pages: 148ra115
Publication
First Author: Li YJ
Year: 2020
Journal: J Am Soc Nephrol
Title: Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid-Mediated Activation of G Protein-Coupled Receptors GPR43 and GPR109A.
Volume: 31
Issue: 6
Pages: 1267-1281
Publication  
First Author: Li YJ
Year: 2023
Journal: Front Cell Dev Biol
Title: Short-chain fatty acids directly exert anti-inflammatory responses in podocytes and tubular epithelial cells exposed to high glucose.
Volume: 11
Pages: 1182570
Publication
First Author: Sonne SR
Year: 2013
Journal: Biochim Biophys Acta
Title: Hyperhomocysteinemia is detrimental to pregnancy in mice and is associated with preterm birth.
Volume: 1832
Issue: 8
Pages: 1149-58
Publication
First Author: Hayashi A
Year: 2021
Journal: J Immunol
Title: The Butyrate-Producing Bacterium Clostridium butyricum Suppresses Clostridioides difficile Infection via Neutrophil- and Antimicrobial Cytokine-Dependent but GPR43/109a-Independent Mechanisms.
Volume: 206
Issue: 7
Pages: 1576-1585
Publication
First Author: Ananth S
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Induction of the cystine/glutamate exchanger SLC7A11 in retinal pigment epithelial cells by the antipsoriatic drug monomethylfumarate.
Volume: 54
Issue: 3
Pages: 1592-602
Publication
First Author: Benyó Z
Year: 2006
Journal: Mol Pharmacol
Title: Nicotinic acid-induced flushing is mediated by activation of epidermal langerhans cells.
Volume: 70
Issue: 6
Pages: 1844-9
Publication
First Author: Hanson J
Year: 2010
Journal: J Clin Invest
Title: Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice.
Volume: 120
Issue: 8
Pages: 2910-9
Publication
First Author: Arpaia N
Year: 2013
Journal: Nature
Title: Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation.
Volume: 504
Issue: 7480
Pages: 451-5
Publication  
First Author: Wang N
Year: 2016
Journal: Gen Comp Endocrinol
Title: Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells.
Volume: 237
Pages: 98-108
Publication      
First Author: Suhrkamp I
Year: 2022
Journal: J Invest Dermatol
Title: Oral Dimethyl Fumarate Targets HCA2-Expressing Skin Cells in the Imiquimod Mouse Model.
Publication
First Author: Viatchenko-Karpinski V
Year: 2022
Journal: Glia
Title: Activation of microglial GPR109A alleviates thermal hyperalgesia in female lupus mice by suppressing IL-18 and glutamatergic synaptic activity.
Volume: 70
Issue: 4
Pages: 634-649
Publication
First Author: Kaye DM
Year: 2020
Journal: Circulation
Title: Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease.
Volume: 141
Issue: 17
Pages: 1393-1403
Publication
First Author: Tan J
Year: 2016
Journal: Cell Rep
Title: Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways.
Volume: 15
Issue: 12
Pages: 2809-24
Publication
First Author: Bhatt B
Year: 2018
Journal: J Immunol
Title: Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation.
Volume: 200
Issue: 8
Pages: 2905-2914
Publication
First Author: Singh N
Year: 2014
Journal: Immunity
Title: Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.
Volume: 40
Issue: 1
Pages: 128-39
Publication
First Author: Gambhir D
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy.
Volume: 53
Issue: 4
Pages: 2208-17
Publication
First Author: Youm YH
Year: 2015
Journal: Nat Med
Title: The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Volume: 21
Issue: 3
Pages: 263-9
Publication  
First Author: Macia L
Year: 2015
Journal: Nat Commun
Title: Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome.
Volume: 6
Pages: 6734
Publication  
First Author: Cook TM
Year: 2021
Journal: Mol Metab
Title: Vagal neuron expression of the microbiota-derived metabolite receptor, free fatty acid receptor (FFAR3), is necessary for normal feeding behavior.
Volume: 54
Pages: 101350
Publication
First Author: Sun H
Year: 2014
Journal: PLoS One
Title: Niacin activates the PI3K/Akt cascade via PKC- and EGFR-transactivation-dependent pathways through hydroxyl-carboxylic acid receptor 2.
Volume: 9
Issue: 11
Pages: e112310
Publication
First Author: Yang W
Year: 2020
Journal: Nat Commun
Title: Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity.
Volume: 11
Issue: 1
Pages: 4457
Publication
First Author: Tumurkhuu G
Year: 2018
Journal: Cell Metab
Title: Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1β Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis.
Volume: 28
Issue: 3
Pages: 432-448.e4
Publication
First Author: Muller PA
Year: 2020
Journal: Nature
Title: Microbiota modulate sympathetic neurons via a gut-brain circuit.
Volume: 583
Issue: 7816
Pages: 441-446
Publication
First Author: Jerome-Majewska LA
Year: 2010
Journal: Dev Biol
Title: The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta.
Volume: 341
Issue: 1
Pages: 154-66
Publication      
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Offermanns S
Year: 2011
Journal: Pharmacol Rev
Title: International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B).
Volume: 63
Issue: 2
Pages: 269-90
Publication
First Author: Wise A
Year: 2003
Journal: J Biol Chem
Title: Molecular identification of high and low affinity receptors for nicotinic acid.
Volume: 278
Issue: 11
Pages: 9869-74
Publication
First Author: Skinner PJ
Year: 2009
Journal: Bioorg Med Chem Lett
Title: 5-N,N-Disubstituted 5-aminopyrazole-3-carboxylic acids are highly potent agonists of GPR109b.
Volume: 19
Issue: 15
Pages: 4207-9
Publication
First Author: Shen HC
Year: 2009
Journal: J Med Chem
Title: Discovery of novel tricyclic full agonists for the G-protein-coupled niacin receptor 109A with minimized flushing in rats.
Volume: 52
Issue: 8
Pages: 2587-602
Publication
First Author: Maciejewski-Lenoir D
Year: 2006
Journal: J Invest Dermatol
Title: Langerhans cells release prostaglandin D2 in response to nicotinic acid.
Volume: 126
Issue: 12
Pages: 2637-46
Publication
First Author: Irukayama-Tomobe Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B.
Volume: 106
Issue: 10
Pages: 3930-4
Publication  
First Author: Ahmed K
Year: 2011
Journal: Front Endocrinol (Lausanne)
Title: Biological roles and therapeutic potential of hydroxy-carboxylic Acid receptors.
Volume: 2
Pages: 51
Publication
First Author: Jiang D
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Monomethyl Fumarate Protects the Retina From Light-Induced Retinopathy.
Volume: 60
Issue: 4
Pages: 1275-1285