|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 408 for Smurf2

<< First    < Previous  |  Next >    Last >>
0.039s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Publication
30566427 | J:269919
First Author: Zhu K
Year: 2018
Journal: PLoS Biol
Title: Non-proteolytic ubiquitin modification of PPARγ by Smurf1 protects the liver from steatosis.
Volume: 16
Issue: 12
Pages: e3000091
•
•
•
•
•
Publication
19805145 | J:153679
First Author: Li DQ
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1.
Volume: 106
Issue: 41
Pages: 17493-8
•
•
•
•
•
Publication
33990575 | J:319807
First Author: Niu B
Year: 2021
Journal: Nat Commun
Title: Interplay between transforming growth factor-β and Nur77 in dual regulations of inhibitor of differentiation 1 for colonic tumorigenesis.
Volume: 12
Issue: 1
Pages: 2809
•
•
•
•
•
Publication
27292644 | J:238299
First Author: Elkouris M
Year: 2016
Journal: Cell Rep
Title: SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis.
Volume: 15
Issue: 12
Pages: 2733-44
•
•
•
•
•
Publication
26147758 | J:250856
First Author: ZeRuth GT
Year: 2015
Journal: PLoS One
Title: HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity.
Volume: 10
Issue: 7
Pages: e0131303
•
•
•
•
•
Publication
29853617 | J:264118
 
First Author: Papoutsi T
Year: 2018
Journal: Development
Title: Bmp2 and Notch cooperate to pattern the embryonic endocardium.
Volume: 145
Issue: 13
•
•
•
•
•
Publication
19580641 | J:156253
First Author: Tateossian H
Year: 2009
Journal: Pathogenetics
Title: Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant.
Volume: 2
Issue: 1
Pages: 5
•
•
•
•
•
Publication
23537899 | J:196581
First Author: Gui T
Year: 2013
Journal: Dev Biol
Title: The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-β signaling.
Volume: 377
Issue: 2
Pages: 415-27
•
•
•
•
•
Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
•
•
•
•
•
Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
•
•
•
•
•
Publication
- | J:345476
       
First Author: Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas
Year: 2023
Title: TreeGrafter-generated GO annotations
•
•
•
•
•
Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
•
•
•
•
•
Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
•
•
•
•
•
Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
•
•
•
•
•
Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
•
•
•
•
•
Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
•
•
•
•
•
Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
•
•
•
•
•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
•
•
•
•
•
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Protein
Q6P066
Organism: Mus musculus/domesticus
Length: 190  
Fragment?: true
•
•
•
•
•
Protein
Q80WX3
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: true
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 1
Description: E3 ubiquitin-protein ligase SMURF2
Type: chain
End: 748
•
•
•
•
•
Protein
A0A338P709
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: false
•
•
•
•
•
Publication
18927080 | J:144574
First Author: Fukunaga E
Year: 2008
Journal: J Biol Chem
Title: Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells.
Volume: 283
Issue: 51
Pages: 35660-7
•
•
•
•
•
Publication
29405587 | J:258505
 
First Author: Borroni AP
Year: 2018
Journal: Aging Cell
Title: Smurf2 regulates stability and the autophagic-lysosomal turnover of lamin A and its disease-associated form progerin.
Volume: 17
Issue: 2
•
•
•
•
•
Publication
15820682 | J:97303
First Author: Yamashita M
Year: 2005
Journal: Cell
Title: Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation.
Volume: 121
Issue: 1
Pages: 101-13
•
•
•
•
•
Interaction Experiment
Tang LY (2011)
Description: Ablation of Smurf2 reveals an inhibition in TGF- signalling through multiple mono-ubiquitination of Smad3.
•
•
•
•
•
Interaction Experiment
Xiao L (2015)
Description: AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by Smurf2 and deubiquitinating enzyme USP4.
•
•
•
•
•
Interaction Experiment
Ganji A (2015)
Description: The effects of WW2/WW3 domains of Smurf2 molecule on TGF- signaling and arginase I gene expression.
•
•
•
•
•
Publication
14755250 | -
First Author: Li H
Year: 2004
Journal: Oncogene
Title: An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein.
Volume: 23
Issue: 10
Pages: 1801-8
•
•
•
•
•
Publication
30696809 | -
First Author: Kim JH
Year: 2019
Journal: Cell Death Dis
Title: TTC3 contributes to TGF-β1-induced epithelial-mesenchymal transition and myofibroblast differentiation, potentially through SMURF2 ubiquitylation and degradation.
Volume: 10
Issue: 2
Pages: 92
•
•
•
•
•
Publication
25885904 | -
 
First Author: Xiao L
Year: 2015
Journal: BMC Cell Biol
Title: AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by Smurf2 and deubiquitinating enzyme USP4.
Volume: 16
Pages: 7
•
•
•
•
•
Publication
25612247 | -
First Author: Ganji A
Year: 2015
Journal: Cell Biol Int
Title: The effects of WW2/WW3 domains of Smurf2 molecule on TGF-β signaling and arginase I gene expression.
Volume: 39
Issue: 6
Pages: 690-5
•
•
•
•
•
Publication
14562029 | -
First Author: Subramaniam V
Year: 2003
Journal: Br J Cancer
Title: The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase.
Volume: 89
Issue: 8
Pages: 1538-44
•
•
•
•
•
Publication
29986870 | J:270532
 
First Author: Iezaki T
Year: 2018
Journal: Development
Title: The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis.
Volume: 145
Issue: 14
•
•
•
•
•
Publication
29100790 | J:257467
First Author: Cai Y
Year: 2018
Journal: Biochim Biophys Acta
Title: Smurf2, an E3 ubiquitin ligase, interacts with PDE4B and attenuates liver fibrosis through miR-132 mediated CTGF inhibition.
Volume: 1865
Issue: 2
Pages: 297-308
•
•
•
•
•
Publication
23973329 | J:203947
First Author: Zhang L
Year: 2013
Journal: Mol Cell
Title: TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.
Volume: 51
Issue: 5
Pages: 559-72
•
•
•
•
•
Publication
31899247 | J:300097
First Author: Fu L
Year: 2020
Journal: Semin Cancer Biol
Title: The functions and regulation of Smurfs in cancers.
Volume: 67
Issue: Pt 2
Pages: 102-116
•
•
•
•
•
Publication
28808068 | J:294012
First Author: Liu Z
Year: 2017
Journal: Hypertension
Title: Deletion of Angiotensin-Converting Enzyme-2 Promotes Hypertensive Nephropathy by Targeting Smad7 for Ubiquitin Degradation.
Volume: 70
Issue: 4
Pages: 822-830
•
•
•
•
•
Publication
16355269 | J:128130
First Author: Li TF
Year: 2006
Journal: J Bone Miner Res
Title: Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation.
Volume: 21
Issue: 1
Pages: 4-16
•
•
•
•
•
Publication
22330342 | J:183414
First Author: Liu Z
Year: 2012
Journal: Lab Invest
Title: Loss of angiotensin-converting enzyme 2 enhances TGF-β/Smad-mediated renal fibrosis and NF-κB-driven renal inflammation in a mouse model of obstructive nephropathy.
Volume: 92
Issue: 5
Pages: 650-61
•
•
•
•
•
Protein Coding Gene
MGI:1923038 | Smurf1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0028003 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0030353 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0030322 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0030254 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0030339 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0030050 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_1923038 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0030784 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0029455 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0030020 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0030170 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0030125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0030256 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0030156 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0030824 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0029170 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0029528 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0024574 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0029006 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
10458166 | J:114795
First Author: Zhu H
Year: 1999
Journal: Nature
Title: A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation.
Volume: 400
Issue: 6745
Pages: 687-93
•
•
•
•
•
Publication
22020285 | J:178302
First Author: Orvedahl A
Year: 2011
Journal: Nature
Title: Image-based genome-wide siRNA screen identifies selective autophagy factors.
Volume: 480
Issue: 7375
Pages: 113-7
•
•
•
•
•
Publication
27214554 | J:237066
First Author: Rothman AM
Year: 2016
Journal: J Clin Invest
Title: MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension.
Volume: 126
Issue: 7
Pages: 2495-508
•
•
•
•
•
Publication
14701828 | J:133077
First Author: Zhao M
Year: 2004
Journal: J Biol Chem
Title: Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo.
Volume: 279
Issue: 13
Pages: 12854-9
•
•
•
•
•
Publication
24631292 | J:211995
First Author: Lee HL
Year: 2014
Journal: Exp Cell Res
Title: Smurf1 plays a role in EGF inhibition of BMP2-induced osteogenic differentiation.
Volume: 323
Issue: 2
Pages: 276-87
•
•
•
•
•
Publication
30143635 | J:266391
First Author: Liang C
Year: 2018
Journal: Nat Commun
Title: Inhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosis.
Volume: 9
Issue: 1
Pages: 3428
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3664758
Assay Type: RT-PCR
Annotation Date: 2006-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672818
Stage: TS18
Assay Id: MGI:3664762
Age: embryonic day 11.0
Specimen Label: E11
Detected: true
Specimen Num: 1
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom