|  Help  |  About  |  Contact Us

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 147 for Casp2

Category restricted to Publication (x)

<< First    < Previous  |  Next >    Last >>
0.041s

Categories

Category: Publication
Type Details Score
Publication
First Author: Tu S
Year: 2006
Journal: Nat Cell Biol
Title: In situ trapping of activated initiator caspases reveals a role for caspase-2 in heat shock-induced apoptosis.
Volume: 8
Issue: 1
Pages: 72-7
Publication
First Author: Kim JY
Year: 2022
Journal: Cell Metab
Title: PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis.
Volume: 34
Issue: 10
Pages: 1548-1560.e6
Publication
First Author: Peintner L
Year: 2015
Journal: Cell Death Differ
Title: The tumor-modulatory effects of Caspase-2 and Pidd1 do not require the scaffold protein Raidd.
Volume: 22
Issue: 11
Pages: 1803-11
Publication
First Author: Manzl C
Year: 2009
Journal: J Cell Biol
Title: Caspase-2 activation in the absence of PIDDosome formation.
Volume: 185
Issue: 2
Pages: 291-303
Publication
First Author: Berube C
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.
Volume: 102
Issue: 40
Pages: 14314-20
Publication
First Author: Jean YY
Year: 2013
Journal: Biochem J
Title: Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death.
Volume: 455
Issue: 1
Pages: 15-25
Publication
First Author: Tinel A
Year: 2004
Journal: Science
Title: The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress.
Volume: 304
Issue: 5672
Pages: 843-6
Publication
First Author: Ando K
Year: 2017
Journal: J Cell Biol
Title: NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus.
Volume: 216
Issue: 6
Pages: 1795-1810
Publication
First Author: Tiwari M
Year: 2014
Journal: Autophagy
Title: A nonapoptotic role for CASP2/caspase 2: modulation of autophagy.
Volume: 10
Issue: 6
Pages: 1054-70
Publication
First Author: Lopez-Cruzan M
Year: 2013
Journal: Biogerontology
Title: Loss of caspase-2 accelerates age-dependent alterations in mitochondrial production of reactive oxygen species.
Volume: 14
Issue: 2
Pages: 121-30
Publication
First Author: Dorstyn L
Year: 2019
Journal: Cell Death Dis
Title: Transcriptome profiling of caspase-2 deficient EμMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling.
Volume: 10
Issue: 2
Pages: 56
Publication  
First Author: Dorstyn L
Year: 2014
Journal: Cell Death Dis
Title: An unexpected role for caspase-2 in neuroblastoma.
Volume: 5
Pages: e1383
Publication
First Author: Parsons MJ
Year: 2013
Journal: Cell Death Differ
Title: Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice.
Volume: 20
Issue: 9
Pages: 1174-82
Publication
First Author: Bergeron L
Year: 1998
Journal: Genes Dev
Title: Defects in regulation of apoptosis in caspase-2-deficient mice.
Volume: 12
Issue: 9
Pages: 1304-14
Publication
First Author: Tiwari M
Year: 2011
Journal: Exp Neurol
Title: A knockout of the caspase 2 gene produces increased resistance of the nigrostriatal dopaminergic pathway to MPTP-induced toxicity.
Volume: 229
Issue: 2
Pages: 421-8
Publication
First Author: Xu ZX
Year: 2019
Journal: Nat Commun
Title: Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling.
Volume: 10
Issue: 1
Pages: 3622
Publication
First Author: Kim JY
Year: 2018
Journal: Cell
Title: ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P.
Volume: 175
Issue: 1
Pages: 133-145.e15
Publication
First Author: Troy CM
Year: 2001
Journal: J Neurosci
Title: Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation.
Volume: 21
Issue: 14
Pages: 5007-16
Publication
First Author: Tiwari M
Year: 2011
Journal: J Biol Chem
Title: Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons.
Volume: 286
Issue: 10
Pages: 8493-506
Publication
First Author: Zhang Y
Year: 2007
Journal: Mech Ageing Dev
Title: Caspase-2 deficiency enhances aging-related traits in mice.
Volume: 128
Issue: 2
Pages: 213-21
Publication
First Author: Sharma R
Year: 2014
Journal: PLoS One
Title: Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts.
Volume: 9
Issue: 4
Pages: e93696
Publication
First Author: Shalini S
Year: 2012
Journal: Cell Death Differ
Title: Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice.
Volume: 19
Issue: 8
Pages: 1370-80
Publication
First Author: Ho LH
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: A tumor suppressor function for caspase-2.
Volume: 106
Issue: 13
Pages: 5336-41
Publication
First Author: Shalini S
Year: 2016
Journal: Cell Death Differ
Title: Caspase-2 deficiency accelerates chemically induced liver cancer in mice.
Volume: 23
Issue: 10
Pages: 1727-36
Publication
First Author: Dorstyn L
Year: 2012
Journal: Cell Death Differ
Title: Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability.
Volume: 19
Issue: 8
Pages: 1288-98
Publication
First Author: Wang L
Year: 1994
Journal: Cell
Title: Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death.
Volume: 78
Issue: 5
Pages: 739-50
Publication
First Author: Allet B
Year: 1996
Journal: J Cell Biol
Title: Dissecting processing and apoptotic activity of a cysteine protease by mutant analysis.
Volume: 135
Issue: 2
Pages: 479-86
Publication  
First Author: Kumar S
Year: 1997
Journal: Leukemia
Title: Characterization of a mammalian cell death gene Nedd2.
Volume: 11 Suppl 3
Pages: 385-6
Publication
First Author: Zheng S
Year: 2006
Journal: Biol Reprod
Title: Caspase 2 activity contributes to the initial wave of germ cell apoptosis during the first round of spermatogenesis.
Volume: 74
Issue: 6
Pages: 1026-33
Publication
First Author: Hanoux V
Year: 2007
Journal: Cell Death Differ
Title: Caspase-2 involvement during ionizing radiation-induced oocyte death in the mouse ovary.
Volume: 14
Issue: 4
Pages: 671-81
Publication
First Author: Chen F
Year: 2011
Journal: Infect Immun
Title: Proinflammatory caspase-2-mediated macrophage cell death induced by a rough attenuated Brucella suis strain.
Volume: 79
Issue: 6
Pages: 2460-9
Publication
First Author: Puccini J
Year: 2013
Journal: Cell Death Differ
Title: Caspase-2 as a tumour suppressor.
Volume: 20
Issue: 9
Pages: 1133-9
Publication
First Author: Dawar S
Year: 2017
Journal: Oncogene
Title: Caspase-2-mediated cell death is required for deleting aneuploid cells.
Volume: 36
Issue: 19
Pages: 2704-2714
Publication  
First Author: Machado MV
Year: 2016
Journal: Cell Death Dis
Title: Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease.
Volume: 7
Pages: e2096
Publication  
First Author: Wilson CH
Year: 2015
Journal: Cell Death Dis
Title: Age-related proteostasis and metabolic alterations in Caspase-2-deficient mice.
Volume: 6
Pages: e1615
Publication
First Author: Kumar S
Year: 1997
Journal: Cell Death Differ
Title: Origin, expression and possible functions of the two alternatively spliced forms of the mouse Nedd2 mRNA.
Volume: 4
Issue: 5
Pages: 378-387
Publication
First Author: Reed JC
Year: 2003
Journal: Genome Res
Title: Comparative analysis of apoptosis and inflammation genes of mice and humans.
Volume: 13
Issue: 6B
Pages: 1376-88
Publication
First Author: Sazuka T
Year: 1992
Journal: Biochem Biophys Res Commun
Title: DRG: a novel developmentally regulated GTP-binding protein.
Volume: 189
Issue: 1
Pages: 363-70
Publication
First Author: Marsden VS
Year: 2004
Journal: J Cell Biol
Title: Bcl-2-regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9.
Volume: 165
Issue: 6
Pages: 775-80
Publication
First Author: Bonzon C
Year: 2006
Journal: Mol Biol Cell
Title: Caspase-2-induced apoptosis requires bid cleavage: a physiological role for bid in heat shock-induced death.
Volume: 17
Issue: 5
Pages: 2150-7
Publication  
First Author: Pozueta J
Year: 2013
Journal: Nat Commun
Title: Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice.
Volume: 4
Pages: 1939
Publication
First Author: Zhao X
Year: 2016
Journal: Nat Med
Title: Caspase-2 cleavage of tau reversibly impairs memory.
Volume: 22
Issue: 11
Pages: 1268-1276
Publication
First Author: Hornum L
Year: 2004
Journal: Mamm Genome
Title: Comparative mapping of rat Iddm4 to segments on HSA7 and MMU6.
Volume: 15
Issue: 1
Pages: 53-61
Publication
First Author: Kumar S
Year: 1994
Journal: Genes Dev
Title: Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme.
Volume: 8
Issue: 14
Pages: 1613-26
Publication
First Author: Puccini J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice.
Volume: 110
Issue: 49
Pages: 19920-5
Publication
First Author: Jablonka S
Year: 2000
Journal: Hum Mol Genet
Title: Reduced survival motor neuron (Smn) gene dose in mice leads to motor neuron degeneration: an animal model for spinal muscular atrophy type III.
Volume: 9
Issue: 3
Pages: 341-6
Publication  
First Author: Callaway DA
Year: 2015
Journal: Bone
Title: Caspase-2 modulates osteoclastogenesis through down-regulating oxidative stress.
Volume: 76
Pages: 40-8
Publication
First Author: Terry MR
Year: 2015
Journal: Cell Death Differ
Title: Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo.
Volume: 22
Issue: 5
Pages: 719-30
Publication
First Author: Manzl C
Year: 2012
Journal: Cell Death Differ
Title: PIDDosome-independent tumor suppression by Caspase-2.
Volume: 19
Issue: 10
Pages: 1722-32
Publication
First Author: Sandow JJ
Year: 2014
Journal: Cell Death Differ
Title: ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis.
Volume: 21
Issue: 3
Pages: 475-80
Publication
First Author: O'Reilly LA
Year: 2002
Journal: Cell Death Differ
Title: Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9.
Volume: 9
Issue: 8
Pages: 832-41
Publication
First Author: Baliga BC
Year: 2003
Journal: J Biol Chem
Title: Role of prodomain in importin-mediated nuclear localization and activation of caspase-2.
Volume: 278
Issue: 7
Pages: 4899-905
Publication
First Author: Häcker G
Year: 1994
Journal: Biochem Cell Biol
Title: Expression of candidate cell death genes in cell lines during apoptosis.
Volume: 72
Issue: 11-12
Pages: 451-4
Publication
First Author: Lamkanfi M
Year: 2005
Journal: J Biol Chem
Title: A novel caspase-2 complex containing TRAF2 and RIP1.
Volume: 280
Issue: 8
Pages: 6923-32
Publication
First Author: Arnault E
Year: 2008
Journal: Dev Dyn
Title: Caspase-2(L), caspase-9, and caspase-3 during in vitro maturation and fragmentation of the mouse oocyte.
Volume: 237
Issue: 12
Pages: 3892-903
Publication
First Author: Shi M
Year: 2009
Journal: Cell
Title: DNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenance.
Volume: 136
Issue: 3
Pages: 508-20
Publication
First Author: Ning X
Year: 2019
Journal: Mol Cell
Title: Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3.
Volume: 74
Issue: 1
Pages: 19-31.e7
Publication
First Author: Upton JP
Year: 2008
Journal: Mol Cell Biol
Title: Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress.
Volume: 28
Issue: 12
Pages: 3943-51
Publication
First Author: Araki T
Year: 1999
Journal: Exp Cell Res
Title: Caspase activity is required for nephrogenesis in the developing mouse metanephros.
Volume: 248
Issue: 2
Pages: 423-9
Publication
First Author: Madesh M
Year: 2009
Journal: Mol Cell Biol
Title: Execution of superoxide-induced cell death by the proapoptotic Bcl-2-related proteins Bid and Bak.
Volume: 29
Issue: 11
Pages: 3099-112
Publication
First Author: Niikura Y
Year: 2010
Journal: Cell Death Differ
Title: BUB3 that dissociates from BUB1 activates caspase-independent mitotic death (CIMD).
Volume: 17
Issue: 6
Pages: 1011-24
Publication
First Author: Van de Craen M
Year: 1997
Journal: FEBS Lett
Title: Characterization of seven murine caspase family members.
Volume: 403
Issue: 1
Pages: 61-9
Publication
First Author: Van de Craen M
Year: 1998
Journal: J Mol Biol
Title: Molecular cloning and identification of murine caspase-8.
Volume: 284
Issue: 4
Pages: 1017-26
Publication
First Author: Zheng TS
Year: 1999
Journal: Cell Death Differ
Title: Caspase knockouts: matters of life and death.
Volume: 6
Issue: 11
Pages: 1043-53
Publication
First Author: Morita Y
Year: 2001
Journal: Cell Death Differ
Title: Caspase-2 deficiency prevents programmed germ cell death resulting from cytokine insufficiency but not meiotic defects caused by loss of ataxia telangiectasia-mutated (Atm) gene function.
Volume: 8
Issue: 6
Pages: 614-20
Publication
First Author: Ren J
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development.
Volume: 102
Issue: 3
Pages: 565-70
Publication
First Author: Zeng Q
Year: 2000
Journal: J Comp Neurol
Title: Gustatory innervation and bax-dependent caspase-2: participants in the life and death pathways of mouse taste receptor cells.
Volume: 424
Issue: 4
Pages: 640-50
Publication
First Author: Sagulenko V
Year: 2013
Journal: Cell Death Differ
Title: AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.
Volume: 20
Issue: 9
Pages: 1149-60
Publication  
First Author: Wang J
Year: 2000
Journal: J Cell Sci
Title: Roles of caspases in apoptosis, development, and cytokine maturation revealed by homozygous gene deficiencies.
Volume: 113 ( Pt 5)
Pages: 753-7
Publication
First Author: Warner CM
Year: 1998
Journal: J Exp Zool
Title: Genetic regulation of preimplantation mouse embryo survival.
Volume: 282
Issue: 1-2
Pages: 272-9
Publication
First Author: Colussi PA
Year: 1999
Journal: Immunol Cell Biol
Title: Targeted disruption of caspase genes in mice: what they tell us about the functions of individual caspases in apoptosis.
Volume: 77
Issue: 1
Pages: 58-63
Publication
First Author: Morita Y
Year: 1999
Journal: Dev Biol
Title: Oocyte apoptosis: like sand through an hourglass.
Volume: 213
Issue: 1
Pages: 1-17
Publication
First Author: Lin CF
Year: 2007
Journal: J Cell Sci
Title: GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis.
Volume: 120
Issue: Pt 16
Pages: 2935-43
Publication
First Author: Tomioka M
Year: 2002
Journal: Brain Res Mol Brain Res
Title: In vivo role of caspases in excitotoxic neuronal death: generation and analysis of transgenic mice expressing baculoviral caspase inhibitor, p35, in postnatal neurons.
Volume: 108
Issue: 1-2
Pages: 18-32
Publication
First Author: Upton JP
Year: 2012
Journal: Science
Title: IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.
Volume: 338
Issue: 6108
Pages: 818-22
Publication
First Author: Kumar S
Year: 1992
Journal: Biochem Biophys Res Commun
Title: Identification of a set of genes with developmentally down-regulated expression in the mouse brain.
Volume: 185
Issue: 3
Pages: 1155-61
Publication
First Author: Kuechle MK
Year: 2001
Journal: Cell Death Differ
Title: Caspase-14, a keratinocyte specific caspase: mRNA splice variants and expression pattern in embryonic and adult mouse.
Volume: 8
Issue: 8
Pages: 868-70
Publication
First Author: Simpson MT
Year: 2001
Journal: J Neurosci
Title: Caspase 3 deficiency rescues peripheral nervous system defect in retinoblastoma nullizygous mice.
Volume: 21
Issue: 18
Pages: 7089-98
Publication
First Author: Venkatesh A
Year: 2015
Journal: J Clin Invest
Title: Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice.
Volume: 125
Issue: 4
Pages: 1446-58
Publication
First Author: Gong T
Year: 2017
Journal: J Immunol
Title: Plant Lectins Activate the NLRP3 Inflammasome To Promote Inflammatory Disorders.
Volume: 198
Issue: 5
Pages: 2082-2092
Publication
First Author: Zheng TS
Year: 2000
Journal: Exp Cell Res
Title: Divinations and surprises: genetic analysis of caspase function in mice.
Volume: 256
Issue: 1
Pages: 67-73
Publication
First Author: Kumar S
Year: 1999
Journal: Trends Biochem Sci
Title: Prodomains--adaptors--oligomerization: the pursuit of caspase activation in apoptosis.
Volume: 24
Issue: 1
Pages: 1-4
Publication
First Author: Los M
Year: 1999
Journal: Immunity
Title: The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.
Volume: 10
Issue: 6
Pages: 629-39
Publication
First Author: Golas A
Year: 2008
Journal: Int J Dev Biol
Title: Gene mapping of sperm quality parameters in recombinant inbred strains of mice.
Volume: 52
Issue: 2-3
Pages: 287-93
Publication
First Author: Exley GE
Year: 1999
Journal: Biol Reprod
Title: Expression of caspase and BCL-2 apoptotic family members in mouse preimplantation embryos.
Volume: 61
Issue: 1
Pages: 231-9
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication
First Author: Vince JE
Year: 2012
Journal: Immunity
Title: Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.
Volume: 36
Issue: 2
Pages: 215-27
Publication
First Author: Roth KA
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Epistatic and independent functions of caspase-3 and Bcl-X(L) in developmental programmed cell death.
Volume: 97
Issue: 1
Pages: 466-71
Publication
First Author: Ikeda T
Year: 2009
Journal: J Vet Med Sci
Title: Expression of caspase family and muscle- and apoptosis-specific genes during skeletal myogenesis in mouse embryo.
Volume: 71
Issue: 9
Pages: 1161-8
Publication
First Author: Rajkovic A
Year: 2004
Journal: Science
Title: NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.
Volume: 305
Issue: 5687
Pages: 1157-9
Publication
First Author: Yeh ML
Year: 2014
Journal: J Neurosci
Title: Robo1 modulates proliferation and neurogenesis in the developing neocortex.
Volume: 34
Issue: 16
Pages: 5717-31
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication
First Author: Hughes CHK
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve.
Volume: 120
Issue: 32
Pages: e2220849120
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73