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Search results 1 to 100 out of 120 for Pikfyve

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Category: Publication
Type Details Score
Publication
First Author: Sbrissa D
Year: 2007
Journal: J Biol Chem
Title: Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.
Volume: 282
Issue: 33
Pages: 23878-91
Publication
First Author: Liggins MC
Year: 2018
Journal: PLoS Genet
Title: PIKfyve regulates melanosome biogenesis.
Volume: 14
Issue: 3
Pages: e1007290
Publication
First Author: Sbrissa D
Year: 2008
Journal: J Mol Biol
Title: ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality.
Volume: 384
Issue: 4
Pages: 766-79
Publication
First Author: Krishna S
Year: 2016
Journal: Dev Cell
Title: PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment.
Volume: 38
Issue: 5
Pages: 536-47
Publication
First Author: Sultana F
Year: 2020
Journal: J Cell Biochem
Title: Snx10 and PIKfyve are required for lysosome formation in osteoclasts.
Volume: 121
Issue: 4
Pages: 2927-2937
Publication
First Author: Hung ST
Year: 2023
Journal: Cell
Title: PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.
Volume: 186
Issue: 4
Pages: 786-802.e28
Publication  
First Author: Tsuruta F
Year: 2015
Journal: Neurosci Lett
Title: PIKfyve mediates the motility of late endosomes and lysosomes in neuronal dendrites.
Volume: 605
Pages: 18-23
Publication
First Author: Jin N
Year: 2008
Journal: EMBO J
Title: VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse.
Volume: 27
Issue: 24
Pages: 3221-34
Publication
First Author: Shisheva A
Year: 2001
Journal: J Biol Chem
Title: Localization and insulin-regulated relocation of phosphoinositide 5-kinase PIKfyve in 3T3-L1 adipocytes.
Volume: 276
Issue: 15
Pages: 11859-69
Publication
First Author: Ikonomov OC
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Muscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switching.
Volume: 305
Issue: 1
Pages: E119-31
Publication  
First Author: Choy CH
Year: 2018
Journal: J Cell Sci
Title: Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence.
Volume: 131
Issue: 10
Publication
First Author: Kawasaki T
Year: 2017
Journal: EMBO J
Title: Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice.
Volume: 36
Issue: 12
Pages: 1707-1718
Publication
First Author: Sbrissa D
Year: 2000
Journal: Biochemistry
Title: PIKfyve lipid kinase is a protein kinase: downregulation of 5'-phosphoinositide product formation by autophosphorylation.
Volume: 39
Issue: 51
Pages: 15980-9
Publication
First Author: Dayam RM
Year: 2017
Journal: J Immunol
Title: The Lipid Kinase PIKfyve Coordinates the Neutrophil Immune Response through the Activation of the Rac GTPase.
Volume: 199
Issue: 6
Pages: 2096-2105
Publication  
First Author: Min SH
Year: 2014
Journal: Nat Commun
Title: Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice.
Volume: 5
Pages: 4691
Publication
First Author: Sbrissa D
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636.
Volume: 303
Issue: 4
Pages: C436-46
Publication  
First Author: Min SH
Year: 2019
Journal: Mol Cell Biol
Title: PIKfyve Deficiency in Myeloid Cells Impairs Lysosomal Homeostasis in Macrophages and Promotes Systemic Inflammation in Mice.
Volume: 39
Issue: 21
Publication
First Author: Ikonomov OC
Year: 2009
Journal: J Biol Chem
Title: Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin.
Volume: 284
Issue: 6
Pages: 3750-61
Publication
First Author: Ikonomov OC
Year: 2003
Journal: J Biol Chem
Title: Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40.
Volume: 278
Issue: 51
Pages: 50863-71
Publication
First Author: Ikonomov OC
Year: 2011
Journal: J Biol Chem
Title: The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice.
Volume: 286
Issue: 15
Pages: 13404-13
Publication
First Author: Zolov SN
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.
Volume: 109
Issue: 43
Pages: 17472-7
Publication
First Author: Ikonomov OC
Year: 2015
Journal: Biochim Biophys Acta
Title: Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis.
Volume: 1853
Issue: 5
Pages: 1240-50
Publication
First Author: Ikonomov OC
Year: 2009
Journal: J Biol Chem
Title: PIKfyve-ArPIKfyve-Sac3 core complex: contact sites and their consequence for Sac3 phosphatase activity and endocytic membrane homeostasis.
Volume: 284
Issue: 51
Pages: 35794-806
Publication
First Author: Cai X
Year: 2014
Journal: J Immunol
Title: PIKfyve, a class III lipid kinase, is required for TLR-induced type I IFN production via modulation of ATF3.
Volume: 192
Issue: 7
Pages: 3383-9
Publication
First Author: Sbrissa D
Year: 2002
Journal: J Biol Chem
Title: Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve. Endomenbrane localization.
Volume: 277
Issue: 8
Pages: 6073-9
Publication
First Author: Ikonomov OC
Year: 2001
Journal: J Biol Chem
Title: Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve.
Volume: 276
Issue: 28
Pages: 26141-7
Publication
First Author: Bridges D
Year: 2012
Journal: Mol Biol Cell
Title: Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1.
Volume: 23
Issue: 15
Pages: 2955-62
Publication
First Author: Sbrissa D
Year: 1999
Journal: J Biol Chem
Title: PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. Effect of insulin.
Volume: 274
Issue: 31
Pages: 21589-97
Publication    
First Author: Mironova YA
Year: 2016
Journal: Elife
Title: PI(3,5)P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms.
Volume: 5
Publication
First Author: Venkatareddy M
Year: 2016
Journal: J Am Soc Nephrol
Title: Distinct Requirements for Vacuolar Protein Sorting 34 Downstream Effector Phosphatidylinositol 3-Phosphate 5-Kinase in Podocytes Versus Proximal Tubular Cells.
Volume: 27
Issue: 9
Pages: 2702-19
Publication
First Author: Vaccari I
Year: 2011
Journal: PLoS Genet
Title: Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies.
Volume: 7
Issue: 10
Pages: e1002319
Publication
First Author: Shisheva A
Year: 1999
Journal: Mol Cell Biol
Title: Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells.
Volume: 19
Issue: 1
Pages: 623-34
Publication  
First Author: Yamazaki M
Year: 2013
Journal: Neurosci Lett
Title: Phosphatidylinositol 4-phosphate 5-kinase β regulates growth cone morphology and semaphorin 3A-triggered growth cone collapse in mouse dorsal root ganglion neurons.
Volume: 547
Pages: 59-64
Publication
First Author: Qin Y
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation.
Volume: 40
Issue: 5
Pages: 1311-1324
Publication
First Author: Halstead JR
Year: 2010
Journal: J Cell Sci
Title: Rac controls PIP5K localisation and PtdIns(4,5)Pâ‚‚ synthesis, which modulates vinculin localisation and neurite dynamics.
Volume: 123
Issue: Pt 20
Pages: 3535-46
Publication
First Author: Akiba Y
Year: 2002
Journal: Brain Res Gene Expr Patterns
Title: Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development.
Volume: 1
Issue: 2
Pages: 123-33
Publication
First Author: Lee HK
Year: 2015
Journal: Neuron
Title: Daam2-PIP5K is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNS.
Volume: 85
Issue: 6
Pages: 1227-43
Publication
First Author: Zhang X
Year: 2023
Journal: Nature
Title: Reprogramming tumour-associated macrophages to outcompete cancer cells.
Volume: 619
Issue: 7970
Pages: 616-623
Publication
First Author: Takasuga S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine.
Volume: 110
Issue: 5
Pages: 1726-31
Publication
First Author: Liang Y
Year: 2013
Journal: Nat Immunol
Title: The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.
Volume: 14
Issue: 8
Pages: 858-66
Publication  
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Sbrissa D
Year: 2004
Journal: Mol Cell Biol
Title: A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity.
Volume: 24
Issue: 23
Pages: 10437-47
Publication
First Author: Compton LM
Year: 2016
Journal: Am J Physiol Cell Physiol
Title: Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency.
Volume: 311
Issue: 3
Pages: C366-77
Publication
First Author: Hill EV
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Regulation of PIKfyve phosphorylation by insulin and osmotic stress.
Volume: 397
Issue: 4
Pages: 650-5
Publication
First Author: Kim J
Year: 2007
Journal: Cancer Res
Title: The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus.
Volume: 67
Issue: 19
Pages: 9229-37
Publication
First Author: Alghamdi TA
Year: 2013
Journal: J Biol Chem
Title: Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and function.
Volume: 288
Issue: 13
Pages: 9363-72
Publication
First Author: Vicinanza M
Year: 2015
Journal: Mol Cell
Title: PI(5)P regulates autophagosome biogenesis.
Volume: 57
Issue: 2
Pages: 219-34
Publication
First Author: Morioka S
Year: 2017
Journal: Exp Cell Res
Title: Phosphoinositide phosphatase Sac3 regulates the cell surface expression of scavenger receptor A and formation of lipid droplets in macrophages.
Volume: 357
Issue: 2
Pages: 252-259
Publication  
First Author: Lenk GM
Year: 2014
Journal: Methods Enzymol
Title: Mouse models of PI(3,5)P2 deficiency with impaired lysosome function.
Volume: 534
Pages: 245-60
Publication
First Author: Zhang Y
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice.
Volume: 104
Issue: 44
Pages: 17518-23
Publication
First Author: Bonangelino CJ
Year: 2002
Journal: J Cell Biol
Title: Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p.
Volume: 156
Issue: 6
Pages: 1015-28
Publication
First Author: Morishita M
Year: 2002
Journal: Genes Cells
Title: Phosphatidylinositol 3-phosphate 5-kinase is required for the cellular response to nutritional starvation and mating pheromone signals in Schizosaccharomyces pombe.
Volume: 7
Issue: 2
Pages: 199-215
Publication
First Author: Miner GE
Year: 2019
Journal: Mol Biol Cell
Title: Phosphatidylinositol 3,5-bisphosphate regulates the transition between trans-SNARE complex formation and vacuole membrane fusion.
Volume: 30
Issue: 2
Pages: 201-208
Publication
First Author: Whitley P
Year: 2009
Journal: Plant Physiol
Title: Arabidopsis FAB1/PIKfyve proteins are essential for development of viable pollen.
Volume: 151
Issue: 4
Pages: 1812-22
Publication
First Author: Hirano T
Year: 2011
Journal: Plant Signal Behav
Title: Arabidopsis FAB1A/B is possibly involved in the recycling of auxin transporters.
Volume: 6
Issue: 4
Pages: 583-5
Publication
First Author: Er EE
Year: 2013
Journal: Sci Signal
Title: AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve.
Volume: 6
Issue: 279
Pages: ra45
Publication
First Author: Kim SM
Year: 2016
Journal: J Clin Invest
Title: Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways.
Volume: 126
Issue: 11
Pages: 4088-4102
Publication
First Author: Liu Y
Year: 2013
Journal: Biochem J
Title: Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle.
Volume: 455
Issue: 2
Pages: 195-206
Publication
First Author: Li X
Year: 2015
Journal: Int Immunol
Title: Mucolipin 1 positively regulates TLR7 responses in dendritic cells by facilitating RNA transportation to lysosomes.
Volume: 27
Issue: 2
Pages: 83-94
Publication
First Author: Yordanov TE
Year: 2019
Journal: Traffic
Title: Biogenesis of lysosome-related organelles complex-1 (BORC) regulates late endosomal/lysosomal size through PIKfyve-dependent phosphatidylinositol-3,5-bisphosphate.
Volume: 20
Issue: 9
Pages: 674-696
Publication
First Author: Ikonomov OC
Year: 2009
Journal: J Biol Chem
Title: Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes.
Volume: 284
Issue: 36
Pages: 23961-71
Publication
First Author: Ikonomov OC
Year: 2015
Journal: J Biol Chem
Title: The Protein Complex of Neurodegeneration-related Phosphoinositide Phosphatase Sac3 and ArPIKfyve Binds the Lewy Body-associated Synphilin-1, Preventing Its Aggregation.
Volume: 290
Issue: 47
Pages: 28515-29
Publication
First Author: Gómez NM
Year: 2018
Journal: FASEB J
Title: Robust lysosomal calcium signaling through channel TRPML1 is impaired by lysosomal lipid accumulation.
Volume: 32
Issue: 2
Pages: 782-794
Publication
First Author: Fernandez-Mosquera L
Year: 2019
Journal: Autophagy
Title: Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis.
Volume: 15
Issue: 9
Pages: 1572-1591