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Search results 1 to 100 out of 159 for Ung

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Category: Publication
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Type Details Score
Publication
26620559 | J:228936
First Author: Xue JH
Year: 2016
Journal: J Biol Chem
Title: Uracil-DNA Glycosylase UNG Promotes Tet-mediated DNA Demethylation.
Volume: 291
Issue: 2
Pages: 731-8
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Publication
27697833 | J:237418
First Author: Cortizas EM
Year: 2016
Journal: J Exp Med
Title: UNG protects B cells from AID-induced telomere loss.
Volume: 213
Issue: 11
Pages: 2459-2472
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Publication
12934097 | J:85353
First Author: Nilsen H
Year: 2003
Journal: Oncogene
Title: Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas.
Volume: 22
Issue: 35
Pages: 5381-6
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Publication
22665573 | J:189103
First Author: Pérez-Durán P
Year: 2012
Journal: J Exp Med
Title: UNG shapes the specificity of AID-induced somatic hypermutation.
Volume: 209
Issue: 7
Pages: 1379-89
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Publication
34471129 | J:310616
First Author: Ung K
Year: 2021
Journal: Nat Commun
Title: Olfactory bulb astrocytes mediate sensory circuit processing through Sox9 in the mouse brain.
Volume: 12
Issue: 1
Pages: 5230
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Publication
11554311 | J:172932
 
First Author: Krokan HE
Year: 2001
Journal: Prog Nucleic Acid Res Mol Biol
Title: Properties and functions of human uracil-DNA glycosylase from the UNG gene.
Volume: 68
Pages: 365-86
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Publication
23140944 | J:196343
First Author: Zan H
Year: 2012
Journal: Cell Rep
Title: Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombination.
Volume: 2
Issue: 5
Pages: 1220-32
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Publication
19596785 | J:152607
First Author: Frieder D
Year: 2009
Journal: Mol Cell Biol
Title: The concerted action of Msh2 and UNG stimulates somatic hypermutation at A . T base pairs.
Volume: 29
Issue: 18
Pages: 5148-57
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Publication
9168124 | J:40051
First Author: Svendsen PC
Year: 1997
Journal: Gene
Title: The mouse uracil-DNA glycosylase gene: isolation of cDNA and genomic clones and mapping ung to mouse chromosome 5.
Volume: 189
Issue: 2
Pages: 175-81
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Publication
28416808 | J:264502
First Author: Ung DC
Year: 2018
Journal: Mol Psychiatry
Title: Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse.
Volume: 23
Issue: 5
Pages: 1356-1367
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Publication
33362210 | J:300808
First Author: Delgado P
Year: 2020
Journal: PLoS Genet
Title: Interplay between UNG and AID governs intratumoral heterogeneity in mature B cell lymphoma.
Volume: 16
Issue: 12
Pages: e1008960
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Publication
21804017 | J:179132
First Author: Ranjit S
Year: 2011
Journal: J Immunol
Title: AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].
Volume: 187
Issue: 5
Pages: 2464-75
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Publication
9016624 | J:38558
First Author: Nilsen H
Year: 1997
Journal: Nucleic Acids Res
Title: Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene.
Volume: 25
Issue: 4
Pages: 750-5
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Publication
15902269 | J:100908
First Author: An Q
Year: 2005
Journal: EMBO J
Title: C --> T mutagenesis and gamma-radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases.
Volume: 24
Issue: 12
Pages: 2205-13
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Publication
22960197 | J:188285
First Author: Li S
Year: 2013
Journal: Mol Immunol
Title: Analysis of Ig gene hypermutation in Ung(-/-)Polh(-/-) mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions.
Volume: 53
Issue: 3
Pages: 214-7
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Publication
30665938 | J:272963
First Author: Zanotti KJ
Year: 2019
Journal: J Immunol
Title: DNA Breaks in Ig V Regions Are Predominantly Single Stranded and Are Generated by UNG and MSH6 DNA Repair Pathways.
Volume: 202
Issue: 5
Pages: 1573-1581
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Publication
28775312 | J:253596
First Author: Alsøe L
Year: 2017
Journal: Sci Rep
Title: Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.
Volume: 7
Issue: 1
Pages: 7199
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Publication
10871356 | J:62858
First Author: Nilsen H
Year: 2000
Journal: Nucleic Acids Res
Title: Analysis of uracil-DNA glycosylases from the murine Ung gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues.
Volume: 28
Issue: 12
Pages: 2277-85
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Publication
10912000 | J:63056
First Author: Nilsen H
Year: 2000
Journal: Mol Cell
Title: Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication.
Volume: 5
Issue: 6
Pages: 1059-65
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Publication
15735713 | J:98053
First Author: Nilsen H
Year: 2005
Journal: Oncogene
Title: Mutation frequencies and AID activation state in B-cell lymphomas from Ung-deficient mice.
Volume: 24
Issue: 18
Pages: 3063-6
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Publication
24591630 | J:207386
First Author: Yousif AS
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase.
Volume: 111
Issue: 11
Pages: E1016-24
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Publication
18614692 | J:138590
First Author: Kronenberg G
Year: 2008
Journal: J Neurosci
Title: Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase.
Volume: 28
Issue: 28
Pages: 7219-30
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Publication
18992744 | J:145614
First Author: Linhart HG
Year: 2009
Journal: Gastroenterology
Title: Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations.
Volume: 136
Issue: 1
Pages: 227-235.e3
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Publication
16301749 | J:118842
First Author: Longerich S
Year: 2005
Journal: J Exp Med
Title: The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions.
Volume: 202
Issue: 10
Pages: 1443-54
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16174566 | J:103664
First Author: Andersen S
Year: 2005
Journal: DNA Repair (Amst)
Title: Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice.
Volume: 4
Issue: 12
Pages: 1432-41
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Publication
12401169 | J:79590
First Author: Rada C
Year: 2002
Journal: Curr Biol
Title: Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice.
Volume: 12
Issue: 20
Pages: 1748-55
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Publication
18070939 | J:130357
First Author: Di Noia JM
Year: 2007
Journal: J Exp Med
Title: Dependence of antibody gene diversification on uracil excision.
Volume: 204
Issue: 13
Pages: 3209-19
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Publication
15199406 | J:90910
First Author: Endres M
Year: 2004
Journal: J Clin Invest
Title: Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase.
Volume: 113
Issue: 12
Pages: 1711-21
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Publication
15494304 | J:94542
First Author: Rada C
Year: 2004
Journal: Mol Cell
Title: Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation.
Volume: 16
Issue: 2
Pages: 163-71
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Publication
17090531 | J:118133
First Author: Begum NA
Year: 2007
Journal: J Biol Chem
Title: Requirement of non-canonical activity of uracil DNA glycosylase for class switch recombination.
Volume: 282
Issue: 1
Pages: 731-42
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Publication
23667108 | J:204859
First Author: Zahn A
Year: 2013
Journal: J Immunol
Title: Separation of function between isotype switching and affinity maturation in vivo during acute immune responses and circulating autoantibodies in UNG-deficient mice.
Volume: 190
Issue: 12
Pages: 5949-60
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Publication
21454529 | J:172684
First Author: Doseth B
Year: 2011
Journal: J Biol Chem
Title: Uracil-DNA glycosylase in base excision repair and adaptive immunity: species differences between man and mouse.
Volume: 286
Issue: 19
Pages: 16669-80
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Publication
18760480 | J:141193
First Author: Zan H
Year: 2008
Journal: Mol Immunol
Title: AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID.
Volume: 46
Issue: 1
Pages: 45-61
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Publication
24710273 | J:221629
First Author: Zivojnovic M
Year: 2014
Journal: Mol Cell Biol
Title: Somatic hypermutation at A/T-rich oligonucleotide substrates shows different strand polarities in Ung-deficient or -proficient backgrounds.
Volume: 34
Issue: 12
Pages: 2176-87
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26385350 | J:231111
First Author: Gu X
Year: 2016
Journal: Blood
Title: AID-associated DNA repair pathways regulate malignant transformation in a murine model of BCL6-driven diffuse large B-cell lymphoma.
Volume: 127
Issue: 1
Pages: 102-12
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24927551 | J:212093
First Author: Stavnezer J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation.
Volume: 111
Issue: 25
Pages: 9217-22
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16407970 | J:144010
First Author: Di Noia JM
Year: 2006
Journal: EMBO J
Title: SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair.
Volume: 25
Issue: 3
Pages: 585-95
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21745813 | J:183034
First Author: Pettersen HS
Year: 2011
Journal: Nucleic Acids Res
Title: UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.
Volume: 39
Issue: 19
Pages: 8430-44
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31757865 | J:293653
First Author: Choi JE
Year: 2020
Journal: J Immunol
Title: AID Phosphorylation Regulates Mismatch Repair-Dependent Class Switch Recombination and Affinity Maturation.
Volume: 204
Issue: 1
Pages: 13-22
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28283534 | J:241575
First Author: Girelli Zubani G
Year: 2017
Journal: J Exp Med
Title: Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs.
Volume: 214
Issue: 4
Pages: 1169-1180
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Publication
17015724 | J:125031
First Author: Shen HM
Year: 2006
Journal: J Immunol
Title: Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice.
Volume: 177
Issue: 8
Pages: 5386-92
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22447450 | J:197809
First Author: Kemmerich K
Year: 2012
Journal: Nucleic Acids Res
Title: Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice.
Volume: 40
Issue: 13
Pages: 6016-25
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16894013 | J:124539
First Author: Xue K
Year: 2006
Journal: J Exp Med
Title: The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice.
Volume: 203
Issue: 9
Pages: 2085-94
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17947680 | J:152998
First Author: Schrader CE
Year: 2007
Journal: J Immunol
Title: Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair.
Volume: 179
Issue: 9
Pages: 6064-71
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11705830 | J:135410
First Author: Li YY
Year: 2001
Journal: Circulation
Title: Mitochondrial abnormalities in tumor necrosis factor-alpha-induced heart failure are associated with impaired DNA repair activity.
Volume: 104
Issue: 20
Pages: 2492-7
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21281628 | J:170857
First Author: Kronenberg G
Year: 2011
Journal: Exp Neurol
Title: Folate deficiency increases mtDNA and D-1 mtDNA deletion in aged brain of mice lacking uracil-DNA glycosylase.
Volume: 228
Issue: 2
Pages: 253-8
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15625295 | J:133877
First Author: Endres M
Year: 2005
Journal: Stroke
Title: Folate deficiency increases postischemic brain injury.
Volume: 36
Issue: 2
Pages: 321-5
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26055793 | J:226367
First Author: Lauritzen KH
Year: 2015
Journal: Am J Physiol Heart Circ Physiol
Title: Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure.
Volume: 309
Issue: 3
Pages: H434-49
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27998928 | J:238776
First Author: Wang Q
Year: 2017
Journal: J Exp Med
Title: The cell cycle restricts activation-induced cytidine deaminase activity to early G1.
Volume: 214
Issue: 1
Pages: 49-58
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24591601 | J:207390
First Author: Zahn A
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination.
Volume: 111
Issue: 11
Pages: E988-97
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29980612 | J:264310
First Author: Galicia G
Year: 2018
Journal: J Immunol
Title: Isotype-Switched Autoantibodies Are Necessary To Facilitate Central Nervous System Autoimmune Disease in Aicda-/- and Ung-/- Mice.
Volume: 201
Issue: 4
Pages: 1119-1130
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25154417 | J:224332
First Author: Shalhout S
Year: 2014
Journal: Mol Cell Biol
Title: Genomic uracil homeostasis during normal B cell maturation and loss of this balance during B cell cancer development.
Volume: 34
Issue: 21
Pages: 4019-32
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29593215 | J:260744
First Author: Methot SP
Year: 2018
Journal: Nat Commun
Title: A licensing step links AID to transcription elongation for mutagenesis in B cells.
Volume: 9
Issue: 1
Pages: 1248
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16103411 | J:100508
First Author: Schrader CE
Year: 2005
Journal: J Exp Med
Title: Inducible DNA breaks in Ig S regions are dependent on AID and UNG.
Volume: 202
Issue: 4
Pages: 561-8
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22314321 | J:183679
First Author: Hakim O
Year: 2012
Journal: Nature
Title: DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes.
Volume: 484
Issue: 7392
Pages: 69-74
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24279473 | J:299422
First Author: Santos F
Year: 2013
Journal: Epigenetics Chromatin
Title: Active demethylation in mouse zygotes involves cytosine deamination and base excision repair.
Volume: 6
Issue: 1
Pages: 39
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23623989 | J:201447
 
First Author: Eckart S
Year: 2013
Journal: Neuroscience
Title: Reduced nerve growth factor levels in stress-related brain regions of folate-deficient mice.
Volume: 245
Pages: 129-35
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22711821 | J:186423
First Author: Kovalchuk AL
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation.
Volume: 109
Issue: 27
Pages: 10972-7
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31795137 | J:306598
 
First Author: Castañeda-Zegarra S
Year: 2019
Journal: Biomolecules
Title: Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren.
Volume: 9
Issue: 12
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29122947 | J:251880
First Author: Mu Y
Year: 2017
Journal: J Exp Med
Title: Phosphorylation promotes activation-induced cytidine deaminase activity at the Myc oncogene.
Volume: 214
Issue: 12
Pages: 3543-3552
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25288395 | J:218675
First Author: Maul RW
Year: 2014
Journal: J Exp Med
Title: Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo-activated cells.
Volume: 211
Issue: 11
Pages: 2297-306
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18273020 | J:132660
First Author: Liu M
Year: 2008
Journal: Nature
Title: Two levels of protection for the B cell genome during somatic hypermutation.
Volume: 451
Issue: 7180
Pages: 841-5
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21151102 | J:167440
First Author: Maul RW
Year: 2011
Journal: Nat Immunol
Title: Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions.
Volume: 12
Issue: 1
Pages: 70-6
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25512519 | J:216931
First Author: Wang Q
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Epigenetic targeting of activation-induced cytidine deaminase.
Volume: 111
Issue: 52
Pages: 18667-72
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19941823 | J:154731
First Author: Robbiani DF
Year: 2009
Journal: Mol Cell
Title: AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.
Volume: 36
Issue: 4
Pages: 631-41
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16765995 | J:118080
First Author: Larsen E
Year: 2007
Journal: Mutat Res
Title: Organ and cell specificity of base excision repair mutants in mice.
Volume: 614
Issue: 1-2
Pages: 56-68
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20691478 | J:167102
First Author: Ratnam S
Year: 2010
Journal: Mol Immunol
Title: The pattern of somatic hypermutation of Ig genes is altered when p53 is inactivated.
Volume: 47
Issue: 16
Pages: 2611-8
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21357694 | J:171127
First Author: Kothandapani A
Year: 2011
Journal: J Biol Chem
Title: Novel role of base excision repair in mediating cisplatin cytotoxicity.
Volume: 286
Issue: 16
Pages: 14564-74
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22768095 | J:187911
First Author: Gramlich HS
Year: 2012
Journal: PLoS One
Title: AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells.
Volume: 7
Issue: 6
Pages: e39601
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30946744 | J:274875
First Author: So CC
Year: 2019
Journal: PLoS Genet
Title: DSB structure impacts DNA recombination leading to class switching and chromosomal translocations in human B cells.
Volume: 15
Issue: 4
Pages: e1008101
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34819670 | J:326431
First Author: Feng Y
Year: 2021
Journal: Nature
Title: FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.
Volume: 600
Issue: 7888
Pages: 324-328
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24244021 | J:207109
First Author: Boulianne B
Year: 2013
Journal: J Immunol
Title: AID and caspase 8 shape the germinal center response through apoptosis.
Volume: 191
Issue: 12
Pages: 5840-7
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19901081 | J:155454
First Author: Krijger PH
Year: 2009
Journal: J Exp Med
Title: Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation.
Volume: 206
Issue: 12
Pages: 2603-11
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24097111 | J:208661
First Author: Vuong BQ
Year: 2013
Journal: Nat Immunol
Title: A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination.
Volume: 14
Issue: 11
Pages: 1183-1189
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Publication
36546838 | J:336101
First Author: Dickinson K
Year: 2023
Journal: Am J Physiol Renal Physiol
Title: WT1 regulates expression of DNA repair gene Neil3 during nephrogenesis.
Volume: 324
Issue: 3
Pages: F245-F255
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Publication
16400328 | J:106450
First Author: Ramiro AR
Year: 2006
Journal: Nature
Title: Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.
Volume: 440
Issue: 7080
Pages: 105-9
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Publication
22403008 | J:187480
First Author: Westendorp B
Year: 2012
Journal: FASEB J
Title: The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy.
Volume: 26
Issue: 6
Pages: 2569-79
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Publication
23920106 | J:202864
First Author: Keil KP
Year: 2013
Journal: Gene Expr Patterns
Title: Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract.
Volume: 13
Issue: 8
Pages: 413-24
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28705898 | J:243411
First Author: Rutledge EA
Year: 2017
Journal: Development
Title: Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Volume: 144
Issue: 17
Pages: 3177-3188
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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