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Search results 1 to 100 out of 399 for Trp53bp1

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Hits by Pathway

Hits by Strain

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Type Details Score
Protein Coding Gene
MGI:1351320 | Trp53bp1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:5693621
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6316062
Age: postnatal adult
Note: Atm-/- mice harbored elevated numbers of Trp53bp1 foci in hippocampus and lung compared to wild type.
Specimen Label: adult Atm-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5693621
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6316062
Age: postnatal adult
Note: Atm-/- mice harbored elevated numbers of Trp53bp1 foci in hippocampus and lung compared to wild type.
Specimen Label: adult Atm-/-
Detected: true
Specimen Num: 2
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Publication
23657012 | J:197442
First Author: Bowman-Colin C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Volume: 110
Issue: 21
Pages: 8632-7
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Protein Coding Gene
MGP_CAROLIEiJ_G0024186 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026385 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026346 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026325 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026359 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026105 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1351320 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026806 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025567 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026081 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026220 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026182 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026321 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026861 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025303 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025636 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025628 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025102 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11934988 | J:76360
First Author: Celeste A
Year: 2002
Journal: Science
Title: Genomic instability in mice lacking histone H2AX.
Volume: 296
Issue: 5569
Pages: 922-7
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Publication
23241889 | J:191725
First Author: Pei H
Year: 2013
Journal: J Immunol
Title: The histone methyltransferase MMSET regulates class switch recombination.
Volume: 190
Issue: 2
Pages: 756-63
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Publication
19414588 | J:151185
First Author: Wu J
Year: 2009
Journal: J Biol Chem
Title: PTIP regulates 53BP1 and SMC1 at the DNA damage sites.
Volume: 284
Issue: 27
Pages: 18078-84
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
26774285 | J:231089
First Author: Tkáč J
Year: 2016
Journal: Mol Cell
Title: HELB Is a Feedback Inhibitor of DNA End Resection.
Volume: 61
Issue: 3
Pages: 405-418
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Publication
30297459 | J:293083
 
First Author: Li ML
Year: 2019
Journal: Mol Cell Biol
Title: Phosphorylation of TIP60 Suppresses 53BP1 Localization at DNA Damage Sites.
Volume: 39
Issue: 1
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Publication
23333305 | J:195061
First Author: Chapman JR
Year: 2013
Journal: Mol Cell
Title: RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.
Volume: 49
Issue: 5
Pages: 858-71
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Publication
23333306 | J:197099
First Author: Escribano-Díaz C
Year: 2013
Journal: Mol Cell
Title: A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
Volume: 49
Issue: 5
Pages: 872-83
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Publication
23306437 | J:193247
First Author: Zimmermann M
Year: 2013
Journal: Science
Title: 53BP1 regulates DSB repair using Rif1 to control 5' end resection.
Volume: 339
Issue: 6120
Pages: 700-4
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Publication
23306439 | J:193246
First Author: Di Virgilio M
Year: 2013
Journal: Science
Title: Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Volume: 339
Issue: 6120
Pages: 711-5
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Publication
8910340 | J:36914
First Author: Datta B
Year: 1996
Journal: J Biol Chem
Title: p202, an interferon-inducible modulator of transcription, inhibits transcriptional activation by the p53 tumor suppressor protein, and a segment from the p53-binding protein 1 that binds to p202 overcomes this inhibition.
Volume: 271
Issue: 44
Pages: 27544-55
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Publication
15542852 | J:94306
First Author: Akhter S
Year: 2004
Journal: Mol Cell Biol
Title: Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress.
Volume: 24
Issue: 23
Pages: 10448-55
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Publication
20080757 | J:156522
First Author: Ramachandran S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination.
Volume: 107
Issue: 2
Pages: 809-14
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Publication
28051062 | J:238544
 
First Author: Liu X
Year: 2017
Journal: Nat Commun
Title: PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice.
Volume: 8
Pages: 13816
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Publication
23714778 | J:197673
First Author: Saxe JP
Year: 2013
Journal: EMBO J
Title: Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline.
Volume: 32
Issue: 13
Pages: 1869-85
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Publication
11801725 | J:74292
First Author: Jullien D
Year: 2002
Journal: J Cell Sci
Title: Kinetochore localisation of the DNA damage response component 53BP1 during mitosis.
Volume: 115
Issue: Pt 1
Pages: 71-9
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Publication
12640136 | J:82512
First Author: Ward IM
Year: 2003
Journal: Mol Cell Biol
Title: p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice.
Volume: 23
Issue: 7
Pages: 2556-63
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Publication
15159415 | J:91130
First Author: Ward IM
Year: 2004
Journal: J Cell Biol
Title: 53BP1 is required for class switch recombination.
Volume: 165
Issue: 4
Pages: 459-64
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Publication
15077110 | J:89802
First Author: Manis JP
Year: 2004
Journal: Nat Immunol
Title: 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.
Volume: 5
Issue: 5
Pages: 481-7
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Publication
20362325 | J:240590
First Author: Bunting SF
Year: 2010
Journal: Cell
Title: 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Volume: 141
Issue: 2
Pages: 243-54
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Publication
23209566 | J:240587
First Author: Hartlerode AJ
Year: 2012
Journal: PLoS One
Title: Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks.
Volume: 7
Issue: 11
Pages: e49211
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Publication
26308889 | J:262446
First Author: Dong J
Year: 2015
Journal: Nature
Title: Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.
Volume: 525
Issue: 7567
Pages: 134-139
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
26123487 | J:224588
First Author: Kato Y
Year: 2015
Journal: Hum Mol Genet
Title: FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.
Volume: 24
Issue: 18
Pages: 5234-49
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Publication
17500065 | J:123598
First Author: Cho YW
Year: 2007
Journal: J Biol Chem
Title: PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.
Volume: 282
Issue: 28
Pages: 20395-406
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Publication
30022168 | J:265301
First Author: Noordermeer SM
Year: 2018
Journal: Nature
Title: The shieldin complex mediates 53BP1-dependent DNA repair.
Volume: 560
Issue: 7716
Pages: 117-121
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Publication
18676810 | J:139510
First Author: Schotta G
Year: 2008
Journal: Genes Dev
Title: A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.
Volume: 22
Issue: 15
Pages: 2048-61
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
38030626 | J:343250
First Author: Ronson GE
Year: 2023
Journal: Nat Commun
Title: Mechanisms of synthetic lethality between BRCA1/2 and 53BP1 deficiencies and DNA polymerase theta targeting.
Volume: 14
Issue: 1
Pages: 7834
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Publication
19876815 | J:159668
First Author: Kim GJ
Year: 2010
Journal: Int J Dev Biol
Title: Dicer is required for Sertoli cell function and survival.
Volume: 54
Issue: 5
Pages: 867-75
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Publication
32051414 | J:286736
First Author: Paiano J
Year: 2020
Journal: Nat Commun
Title: ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis.
Volume: 11
Issue: 1
Pages: 857
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Publication
22445484 | J:183455
First Author: Bunting SF
Year: 2012
Journal: Mol Cell
Title: BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair.
Volume: 46
Issue: 2
Pages: 125-35
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Publication
29078319 | J:271417
First Author: Su D
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: PTIP chromatin regulator controls development and activation of B cell subsets to license humoral immunity in mice.
Volume: 114
Issue: 44
Pages: E9328-E9337
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Publication
24914237 | J:215795
First Author: Broering TJ
Year: 2014
Journal: J Cell Biol
Title: BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis.
Volume: 205
Issue: 5
Pages: 663-75
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Publication
32139898 | J:302675
First Author: Chen J
Year: 2020
Journal: Cell Death Differ
Title: 53BP1 loss rescues embryonic lethality but not genomic instability of BRCA1 total knockout mice.
Volume: 27
Issue: 9
Pages: 2552-2567
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Publication
33857404 | J:307190
First Author: Shinoda K
Year: 2021
Journal: Mol Cell
Title: The dystonia gene THAP1 controls DNA double-strand break repair choice.
Volume: 81
Issue: 12
Pages: 2611-2624.e10
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Publication
30704900 | J:274082
First Author: Zong D
Year: 2019
Journal: Mol Cell
Title: BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
Volume: 73
Issue: 6
Pages: 1267-1281.e7
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Publication
- | J:82961
     
First Author: JAX National Heart, Lung and Blood Program for Genomic Applications (PGA)
Year: 2003
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the JAX NHLBI ENU Mutagenesis Program
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Publication
31541646 | J:288654
First Author: Lun MP
Year: 2019
Journal: Am J Pathol
Title: Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome.
Volume: 189
Issue: 12
Pages: 2440-2449
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Publication
34050161 | J:306061
First Author: Damen M
Year: 2021
Journal: Nat Commun
Title: High proliferation and delamination during skin epidermal stratification.
Volume: 12
Issue: 1
Pages: 3227
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Publication
24706806 | J:208632
First Author: Bazzi H
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo.
Volume: 111
Issue: 15
Pages: E1491-500
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Publication
33410253 | J:302304
First Author: Xiao C
Year: 2021
Journal: EMBO Rep
Title: Gradual centriole maturation associates with the mitotic surveillance pathway in mouse development.
Volume: 22
Issue: 2
Pages: e51127
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Publication
30530501 | J:271222
First Author: Barazas M
Year: 2019
Journal: Cancer Res
Title: Radiosensitivity Is an Acquired Vulnerability of PARPi-Resistant BRCA1-Deficient Tumors.
Volume: 79
Issue: 3
Pages: 452-460
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Publication
23271346 | J:192592
First Author: Sotiropoulou PA
Year: 2013
Journal: Genes Dev
Title: BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny.
Volume: 27
Issue: 1
Pages: 39-51
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Publication
23727112 | J:198413
First Author: Callen E
Year: 2013
Journal: Cell
Title: 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Volume: 153
Issue: 6
Pages: 1266-80
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Publication
19716796 | J:154193
First Author: Cao L
Year: 2009
Journal: Mol Cell
Title: A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
Volume: 35
Issue: 4
Pages: 534-41
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Publication
30257212 | J:271205
First Author: Nacson J
Year: 2018
Journal: Cell Rep
Title: BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance.
Volume: 24
Issue: 13
Pages: 3513-3527.e7
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Publication
30352856 | J:266868
First Author: Sasanuma H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes.
Volume: 115
Issue: 45
Pages: E10642-E10651
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Publication
31653568 | J:286257
First Author: Callen E
Year: 2020
Journal: Mol Cell
Title: 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.
Volume: 77
Issue: 1
Pages: 26-38.e7
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Publication
24842372 | J:213733
First Author: Polato F
Year: 2014
Journal: J Exp Med
Title: CtIP-mediated resection is essential for viability and can operate independently of BRCA1.
Volume: 211
Issue: 6
Pages: 1027-36
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Publication
35969748 | J:327430
First Author: Yang Y
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Transcription-replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability.
Volume: 119
Issue: 34
Pages: e2203208119
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Publication
23345425 | J:194338
First Author: Lottersberger F
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Role of 53BP1 oligomerization in regulating double-strand break repair.
Volume: 110
Issue: 6
Pages: 2146-51
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Publication
22556254 | J:184522
First Author: Sfeir A
Year: 2012
Journal: Science
Title: Removal of shelterin reveals the telomere end-protection problem.
Volume: 336
Issue: 6081
Pages: 593-7
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Publication
18931659 | J:143563
First Author: Dimitrova N
Year: 2008
Journal: Nature
Title: 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.
Volume: 456
Issue: 7221
Pages: 524-8
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Publication
26303202 | J:233378
First Author: Barazzuol L
Year: 2015
Journal: J Cell Sci
Title: Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells.
Volume: 128
Issue: 19
Pages: 3597-606
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Publication
21734301 | J:174554
First Author: Gatz SA
Year: 2011
Journal: J Neurosci
Title: Requirement for DNA ligase IV during embryonic neuronal development.
Volume: 31
Issue: 27
Pages: 10088-100
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Publication
17599403 | J:143821
First Author: Callén E
Year: 2007
Journal: Cell
Title: ATM prevents the persistence and propagation of chromosome breaks in lymphocytes.
Volume: 130
Issue: 1
Pages: 63-75
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Publication
25264618 | J:222492
First Author: Rybanska-Spaeder I
Year: 2014
Journal: PLoS One
Title: 53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.
Volume: 9
Issue: 9
Pages: e108731
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Publication
20231360 | J:162591
First Author: Orsburn B
Year: 2010
Journal: Mol Cell Biol
Title: Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.
Volume: 30
Issue: 10
Pages: 2341-52
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Publication
33200984 | J:299451
   
First Author: Atkins A
Year: 2020
Journal: Elife
Title: SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis.
Volume: 9
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Publication
27670884 | J:237991
First Author: Li M
Year: 2016
Journal: EMBO Rep
Title: 53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1.
Volume: 17
Issue: 11
Pages: 1532-1541
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Publication
29520062 | J:260101
First Author: Li C
Year: 2018
Journal: Nat Commun
Title: The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining.
Volume: 9
Issue: 1
Pages: 1006
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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