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Search results 2901 to 3000 out of 3928 for Mtor

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Type Details Score
Publication
18974783 | J:143922
First Author: Chen J
Year: 2008
Journal: PLoS One
Title: Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia.
Volume: 3
Issue: 10
Pages: e3581
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22709692 | J:189078
First Author: Baba M
Year: 2012
Journal: Blood
Title: The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development.
Volume: 120
Issue: 6
Pages: 1254-61
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29897930 | J:262829
First Author: Centini R
Year: 2018
Journal: PLoS One
Title: Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation.
Volume: 13
Issue: 6
Pages: e0197973
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Publication
29330505 | J:260197
First Author: Ruiz A
Year: 2018
Journal: Sci Rep
Title: Over-expression of a retinol dehydrogenase (SRP35/DHRS7C) in skeletal muscle activates mTORC2, enhances glucose metabolism and muscle performance.
Volume: 8
Issue: 1
Pages: 636
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Publication
27378698 | J:237861
First Author: Magalhaes J
Year: 2016
Journal: Hum Mol Genet
Title: Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease.
Volume: 25
Issue: 16
Pages: 3432-3445
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15705789 | J:98472
First Author: Hammerman PS
Year: 2005
Journal: Blood
Title: Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival.
Volume: 105
Issue: 11
Pages: 4477-83
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17476689 | J:153319
First Author: Bohensky J
Year: 2007
Journal: J Cell Physiol
Title: PIM-2 is an independent regulator of chondrocyte survival and autophagy in the epiphyseal growth plate.
Volume: 213
Issue: 1
Pages: 246-51
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Publication
23695157 | J:201107
First Author: Al-Qusairi L
Year: 2013
Journal: FASEB J
Title: Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways.
Volume: 27
Issue: 8
Pages: 3384-94
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Publication
18347057 | J:136089
First Author: Bayascas JR
Year: 2008
Journal: Mol Cell Biol
Title: Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Volume: 28
Issue: 10
Pages: 3258-72
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Publication
25139996 | J:216403
First Author: Nikonova AS
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Nedd9 restrains renal cystogenesis in Pkd1-/- mice.
Volume: 111
Issue: 35
Pages: 12859-64
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Publication
29288408 | J:272348
First Author: Wu W
Year: 2018
Journal: J Physiol Biochem
Title: Muscle-specific deletion of Prkaa1 enhances skeletal muscle lipid accumulation in mice fed a high-fat diet.
Volume: 74
Issue: 2
Pages: 195-205
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Publication
31584633 | J:306742
First Author: Oka SI
Year: 2020
Journal: Cardiovasc Res
Title: Thioredoxin-1 maintains mitochondrial function via mechanistic target of rapamycin signalling in the heart.
Volume: 116
Issue: 10
Pages: 1742-1755
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Publication
26378024 | J:291741
First Author: Chang J
Year: 2015
Journal: Oncotarget
Title: Prostaglandin E receptor 4 (EP4) promotes colonic tumorigenesis.
Volume: 6
Issue: 32
Pages: 33500-11
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29864452 | J:264085
 
First Author: Montesinos J
Year: 2018
Journal: Neurosci Lett
Title: Binge-like ethanol treatment in adolescence impairs autophagy and hinders synaptic maturation: Role of TLR4.
Volume: 682
Pages: 85-91
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36443301 | J:331960
First Author: Huang Z
Year: 2022
Journal: Nat Commun
Title: mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome.
Volume: 13
Issue: 1
Pages: 6915
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26367276 | J:245813
First Author: Nanjappa SG
Year: 2015
Journal: PLoS Pathog
Title: Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia.
Volume: 11
Issue: 9
Pages: e1005161
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Publication
26740601 | J:249608
First Author: Stamateris RE
Year: 2016
Journal: Diabetes
Title: Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.
Volume: 65
Issue: 4
Pages: 981-95
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29083325 | J:250089
     
First Author: Kang HS
Year: 2017
Journal: J Clin Invest
Title: GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation.
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31167126 | J:283524
First Author: Yang L
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: CD74 knockout attenuates alcohol intake-induced cardiac dysfunction through AMPK-Skp2-mediated regulation of autophagy.
Volume: 1865
Issue: 9
Pages: 2368-2378
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25339759 | J:217151
First Author: Shibuya Y
Year: 2014
Journal: J Neurosci
Title: Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance.
Volume: 34
Issue: 43
Pages: 14484-501
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29501742 | J:273677
First Author: Li H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling.
Volume: 498
Issue: 1
Pages: 234-239
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22960314 | J:192478
 
First Author: Algarzae N
Year: 2012
Journal: Neuroscience
Title: Parkin prevents cortical atrophy and Aβ-induced alterations of brain metabolism: ¹³C NMR and magnetic resonance imaging studies in AD models.
Volume: 225
Pages: 22-34
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25304685 | J:219673
First Author: Kocher BA
Year: 2015
Journal: Mol Cancer Res
Title: DAPK3 suppresses acini morphogenesis and is required for mouse development.
Volume: 13
Issue: 2
Pages: 358-67
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11909972 | J:75780
First Author: Shioi T
Year: 2002
Journal: Mol Cell Biol
Title: Akt/protein kinase B promotes organ growth in transgenic mice.
Volume: 22
Issue: 8
Pages: 2799-809
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25535334 | J:224296
First Author: Wende AR
Year: 2015
Journal: Mol Cell Biol
Title: Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.
Volume: 35
Issue: 5
Pages: 831-46
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34228176 | J:324585
First Author: Figueiredo M
Year: 2021
Journal: Pflugers Arch
Title: The (pro)renin receptor (ATP6ap2) facilitates receptor-mediated endocytosis and lysosomal function in the renal proximal tubule.
Volume: 473
Issue: 8
Pages: 1229-1246
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29374060 | J:262854
First Author: Zhang J
Year: 2018
Journal: J Biol Chem
Title: S-Glutathionylation of estrogen receptor α affects dendritic cell function.
Volume: 293
Issue: 12
Pages: 4366-4380
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23832089 | J:199992
First Author: Pajvani UB
Year: 2013
Journal: Nat Med
Title: Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability.
Volume: 19
Issue: 8
Pages: 1054-60
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26271103 | J:226632
First Author: Demitrack ES
Year: 2015
Journal: EMBO J
Title: Notch signaling regulates gastric antral LGR5 stem cell function.
Volume: 34
Issue: 20
Pages: 2522-36
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27270670 | J:249539
First Author: Baj G
Year: 2016
Journal: J Cell Sci
Title: Signaling pathways controlling activity-dependent local translation of BDNF and their localization in dendritic arbors.
Volume: 129
Issue: 14
Pages: 2852-64
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29717938 | J:280706
First Author: Kipp KR
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Comparison of folate-conjugated rapamycin versus unconjugated rapamycin in an orthologous mouse model of polycystic kidney disease.
Volume: 315
Issue: 2
Pages: F395-F405
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21319287 | J:215873
First Author: Wu J
Year: 2012
Journal: Pediatr Blood Cancer
Title: Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging.
Volume: 58
Issue: 2
Pages: 173-80
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Publication
31122699 | J:291195
First Author: Zhang SJ
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Schwann cell-specific PTEN and EGFR dysfunctions affect neuromuscular junction development by impairing Agrin signaling and autophagy.
Volume: 515
Issue: 1
Pages: 50-56
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Publication
34787081 | J:314954
   
First Author: Conde-Dusman MJ
Year: 2021
Journal: Elife
Title: Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly.
Volume: 10
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34324436 | J:312839
 
First Author: Chen HR
Year: 2021
Journal: JCI Insight
Title: Creatine transporter deficiency impairs stress adaptation and brain energetics homeostasis.
Volume: 6
Issue: 17
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Publication
22412198 | J:184070
First Author: Pan H
Year: 2012
Journal: J Immunol
Title: The role of tuberous sclerosis complex 1 in regulating innate immunity.
Volume: 188
Issue: 8
Pages: 3658-66
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24064341 | J:205003
First Author: Auffret J
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Defective prolactin signaling impairs pancreatic β-cell development during the perinatal period.
Volume: 305
Issue: 10
Pages: E1309-18
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Publication
29938573 | J:302615
First Author: Yeo SK
Year: 2018
Journal: Autophagy
Title: Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer.
Volume: 14
Issue: 7
Pages: 1214-1225
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Publication
36478736 | J:331988
 
First Author: Istiaq A
Year: 2022
Journal: Front Cell Dev Biol
Title: Tsukushi proteoglycan maintains RNA splicing and developmental signaling network in GFAP-expressing subventricular zone neural stem/progenitor cells.
Volume: 10
Pages: 994588
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Publication
22662254 | J:187301
First Author: Esteves CL
Year: 2012
Journal: PLoS One
Title: Regulation of adipocyte 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) by CCAAT/enhancer-binding protein (C/EBP) β isoforms, LIP and LAP.
Volume: 7
Issue: 5
Pages: e37953
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Publication
24785297 | J:211065
First Author: Park H
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Metabolic regulator Fnip1 is crucial for iNKT lymphocyte development.
Volume: 111
Issue: 19
Pages: 7066-71
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20072130 | J:162611
First Author: Janes MR
Year: 2010
Journal: Nat Med
Title: Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
Volume: 16
Issue: 2
Pages: 205-13
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35971771 | J:328707
   
First Author: Romero-Becerra R
Year: 2022
Journal: Elife
Title: MKK6 deficiency promotes cardiac dysfunction through MKK3-p38γ/δ-mTOR hyperactivation.
Volume: 11
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Publication
34440840 | J:311075
 
First Author: Biasizzo M
Year: 2021
Journal: Cells
Title: Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice.
Volume: 10
Issue: 8
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22351927 | J:181685
First Author: Bakkar N
Year: 2012
Journal: J Cell Biol
Title: IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism.
Volume: 196
Issue: 4
Pages: 497-511
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Publication
34571934 | J:311506
 
First Author: Peng Y
Year: 2021
Journal: Cells
Title: Substrate Reduction Therapy Reverses Mitochondrial, mTOR, and Autophagy Alterations in a Cell Model of Gaucher Disease.
Volume: 10
Issue: 9
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Publication
32591410 | J:296309
First Author: Yamauchi Y
Year: 2020
Journal: Cancer Res
Title: Rb and p53 Execute Distinct Roles in the Development of Pancreatic Neuroendocrine Tumors.
Volume: 80
Issue: 17
Pages: 3620-3630
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26420838 | J:226843
First Author: Dasgupta N
Year: 2015
Journal: Hum Mol Genet
Title: Neuronopathic Gaucher disease: dysregulated mRNAs and miRNAs in brain pathogenesis and effects of pharmacologic chaperone treatment in a mouse model.
Volume: 24
Issue: 24
Pages: 7031-48
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Publication
36125265 | J:330376
First Author: Riehle C
Year: 2022
Journal: Mol Cell Biol
Title: Insulin and Insulin-Like Growth Factor 1 Signaling Preserves Sarcomere Integrity in the Adult Heart.
Volume: 42
Issue: 10
Pages: e0016322
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Publication
26240281 | J:228222
First Author: Nakagawa T
Year: 2015
Journal: Mol Cell Biol
Title: S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation.
Volume: 35
Issue: 20
Pages: 3517-27
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29643507 | J:261638
First Author: Liakath-Ali K
Year: 2018
Journal: Nature
Title: An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis.
Volume: 556
Issue: 7701
Pages: 376-380
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30848941 | J:294073
First Author: Shi J
Year: 2019
Journal: FASEB J
Title: Disruption of both ROCK1 and ROCK2 genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging.
Volume: 33
Issue: 6
Pages: 7348-7362
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16166381 | J:100952
First Author: Ruvinsky I
Year: 2005
Journal: Genes Dev
Title: Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis.
Volume: 19
Issue: 18
Pages: 2199-211
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37068088 | J:335072
First Author: Decourt C
Year: 2023
Journal: PLoS Biol
Title: The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems.
Volume: 21
Issue: 4
Pages: e3002044
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26283674 | J:293583
First Author: Volovelsky O
Year: 2016
Journal: J Am Soc Nephrol
Title: Phosphorylation of Ribosomal Protein S6 Mediates Mammalian Target of Rapamycin Complex 1-Induced Parathyroid Cell Proliferation in Secondary Hyperparathyroidism.
Volume: 27
Issue: 4
Pages: 1091-101
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19808022 | J:153660
First Author: Granot Z
Year: 2009
Journal: Cell Metab
Title: LKB1 regulates pancreatic beta cell size, polarity, and function.
Volume: 10
Issue: 4
Pages: 296-308
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16908864 | J:112917
First Author: Rossi F
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor.
Volume: 103
Issue: 34
Pages: 12843-8
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33239450 | J:307110
First Author: Bozadjieva Kramer N
Year: 2021
Journal: Diabetes
Title: Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia.
Volume: 70
Issue: 2
Pages: 477-491
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25094045 | J:220115
First Author: Arumugam A
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch.
Volume: 451
Issue: 3
Pages: 394-401
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24705297 | J:209960
First Author: Heikamp EB
Year: 2014
Journal: Nat Immunol
Title: The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex.
Volume: 15
Issue: 5
Pages: 457-64
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21805467 | J:179527
First Author: O'Brien TF
Year: 2011
Journal: Eur J Immunol
Title: Regulation of T-cell survival and mitochondrial homeostasis by TSC1.
Volume: 41
Issue: 11
Pages: 3361-70
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22993204 | J:190634
First Author: Zhao YG
Year: 2012
Journal: J Immunol
Title: Dihydroartemisinin ameliorates inflammatory disease by its reciprocal effects on Th and regulatory T cell function via modulating the mammalian target of rapamycin pathway.
Volume: 189
Issue: 9
Pages: 4417-25
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34949833 | J:325023
First Author: Wang Y
Year: 2022
Journal: Nat Immunol
Title: The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis.
Volume: 23
Issue: 2
Pages: 303-317
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25607841 | J:217651
First Author: Zhang Y
Year: 2015
Journal: J Clin Invest
Title: GP96 is a GARP chaperone and controls regulatory T cell functions.
Volume: 125
Issue: 2
Pages: 859-69
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24614103 | J:209612
First Author: Wu J
Year: 2014
Journal: J Clin Invest
Title: iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.
Volume: 124
Issue: 4
Pages: 1685-98
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34403361 | J:340069
 
First Author: Wang F
Year: 2021
Journal: J Clin Invest
Title: ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells.
Volume: 131
Issue: 19
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27889578 | J:238268
 
First Author: Switon K
Year: 2017
Journal: Neuroscience
Title: Molecular neurobiology of mTOR.
Volume: 341
Pages: 112-153
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19738049 | J:152687
First Author: Bhatia B
Year: 2009
Journal: Cancer Res
Title: Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization.
Volume: 69
Issue: 18
Pages: 7224-34
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22538705 | J:183988
First Author: Kowalczyk MS
Year: 2012
Journal: Mamm Genome
Title: Nprl3 is required for normal development of the cardiovascular system.
Volume: 23
Issue: 7-8
Pages: 404-15
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21846906 | J:182171
First Author: Kim MK
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Promyelocytic leukemia inhibits adipogenesis, and loss of promyelocytic leukemia results in fat accumulation in mice.
Volume: 301
Issue: 6
Pages: E1130-42
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24101677 | J:209030
First Author: Guzman J
Year: 2014
Journal: Diabetes
Title: Podocyte-specific GLUT4-deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy.
Volume: 63
Issue: 2
Pages: 701-14
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31353861 | J:346642
First Author: Koene LMC
Year: 2019
Journal: Ann Clin Transl Neurol
Title: Effects of antiepileptic drugs in a new TSC/mTOR-dependent epilepsy mouse model.
Volume: 6
Issue: 7
Pages: 1273-1291
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34877936 | J:336479
 
First Author: Koene LM
Year: 2021
Journal: JCI Insight
Title: Identifying the temporal electrophysiological and molecular changes that contribute to TSC-associated epileptogenesis.
Volume: 6
Issue: 23
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21124450 | J:165090
First Author: Nakada D
Year: 2010
Journal: Nature
Title: Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells.
Volume: 468
Issue: 7324
Pages: 653-8
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24295634 | J:207923
 
First Author: Ramamurthy S
Year: 2014
Journal: Neuroscience
Title: AMPK activation regulates neuronal structure in developing hippocampal neurons.
Volume: 259
Pages: 13-24
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28085543 | J:274495
First Author: Wang Q
Year: 2017
Journal: Autophagy
Title: Deletion of PRKAA triggers mitochondrial fission by inhibiting the autophagy-dependent degradation of DNM1L.
Volume: 13
Issue: 2
Pages: 404-422
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Publication
27737881 | J:238434
First Author: Liu Y
Year: 2017
Journal: Cancer Res
Title: Biphasic Rapamycin Effects in Lymphoma and Carcinoma Treatment.
Volume: 77
Issue: 2
Pages: 520-531
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31324720 | J:281313
First Author: Schweig JE
Year: 2019
Journal: J Biol Chem
Title: Spleen tyrosine kinase (SYK) blocks autophagic Tau degradation in vitro and in vivo.
Volume: 294
Issue: 36
Pages: 13378-13395
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26019175 | J:223927
First Author: Iwayama T
Year: 2015
Journal: Genes Dev
Title: PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity.
Volume: 29
Issue: 11
Pages: 1106-19
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30594669 | J:291320
 
First Author: Song HL
Year: 2019
Journal: Mol Cell Neurosci
Title: Ouabain activates transcription factor EB and exerts neuroprotection in models of Alzheimer's disease.
Volume: 95
Pages: 13-24
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26577921 | J:301636
First Author: Hsieh AC
Year: 2015
Journal: Sci Signal
Title: Cell type-specific abundance of 4EBP1 primes prostate cancer sensitivity or resistance to PI3K pathway inhibitors.
Volume: 8
Issue: 403
Pages: ra116
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21493594 | J:170965
First Author: Ellwood-Yen K
Year: 2011
Journal: Cancer Res
Title: PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models.
Volume: 71
Issue: 8
Pages: 3052-65
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Publication
28319045 | J:243606
First Author: Li N
Year: 2017
Journal: J Clin Invest
Title: AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis.
Volume: 127
Issue: 4
Pages: 1284-1302
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26403076 | J:242957
First Author: Kazdoba TM
Year: 2016
Journal: Genes Brain Behav
Title: Behavioral phenotypes of genetic mouse models of autism.
Volume: 15
Issue: 1
Pages: 7-26
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30816216 | J:275431
First Author: Xing X
Year: 2019
Journal: Sci Rep
Title: Suppression of Akt-mTOR pathway rescued the social behavior in Cntnap2-deficient mice.
Volume: 9
Issue: 1
Pages: 3041
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