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Search results 2101 to 2200 out of 2536 for Fgfr1

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Type Details Score
Publication
First Author: Dumont DJ
Year: 1992
Journal: Oncogene
Title: tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors.
Volume: 7
Issue: 8
Pages: 1471-80
Publication
First Author: Shimizu A
Year: 2001
Journal: J Biol Chem
Title: A novel alternatively spliced fibroblast growth factor receptor 3 isoform lacking the acid box domain is expressed during chondrogenic differentiation of ATDC5 cells.
Volume: 276
Issue: 14
Pages: 11031-40
Publication
First Author: McGowan SE
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Fibroblast growth factor signaling in myofibroblasts differs from lipofibroblasts during alveolar septation in mice.
Volume: 309
Issue: 5
Pages: L463-74
Publication
First Author: Kim CS
Year: 2007
Journal: Carcinogenesis
Title: The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer.
Volume: 28
Issue: 5
Pages: 932-9
Publication
First Author: Xu C
Year: 2017
Journal: EMBO Mol Med
Title: KLB, encoding β-Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism.
Volume: 9
Issue: 10
Pages: 1379-1397
Publication
First Author: Wu AL
Year: 2011
Journal: Sci Transl Med
Title: Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1.
Volume: 3
Issue: 113
Pages: 113ra126
Publication
First Author: Sims-Lucas S
Year: 2011
Journal: Development
Title: Independent roles of Fgfr2 and Frs2alpha in ureteric epithelium.
Volume: 138
Issue: 7
Pages: 1275-80
Publication
First Author: Chen PY
Year: 2015
Journal: J Clin Invest
Title: Endothelial-to-mesenchymal transition drives atherosclerosis progression.
Volume: 125
Issue: 12
Pages: 4514-28
Publication
First Author: Zhou Y
Year: 2019
Journal: J Cell Physiol
Title: Deletion of Axin1 in condylar chondrocytes leads to osteoarthritis-like phenotype in temporomandibular joint via activation of β-catenin and FGF signaling.
Volume: 234
Issue: 2
Pages: 1720-1729
Publication
First Author: Agerstam H
Year: 2010
Journal: Blood
Title: Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice.
Volume: 116
Issue: 12
Pages: 2103-11
Publication  
First Author: Jürgenson M
Year: 2012
Journal: Brain Res
Title: Partial reduction in neural cell adhesion molecule (NCAM) in heterozygous mice induces depression-related behaviour without cognitive impairment.
Volume: 1447
Pages: 106-18
Publication
First Author: Kuny S
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Differential gene expression in eyecup and retina of a mouse model of Stargardt-like macular dystrophy (STGD3).
Volume: 53
Issue: 2
Pages: 664-75
Publication
First Author: Bøllehuus Hansen L
Year: 2020
Journal: FASEB J
Title: Influence of FGF23 and Klotho on male reproduction: Systemic vs direct effects.
Volume: 34
Issue: 9
Pages: 12436-12449
Publication
First Author: Nagpal P
Year: 2012
Journal: PLoS One
Title: The ubiquitin ligase Nedd4-1 participates in denervation-induced skeletal muscle atrophy in mice.
Volume: 7
Issue: 10
Pages: e46427
Publication
First Author: Burt PM
Year: 2019
Journal: J Cell Physiol
Title: Ablation of low-molecular-weight FGF2 isoform accelerates murine osteoarthritis while loss of high-molecular-weight FGF2 isoforms offers protection.
Volume: 234
Issue: 4
Pages: 4418-4431
Publication  
First Author: Herburg L
Year: 2023
Journal: Int J Mol Sci
Title: Chronic Voluntary Alcohol Consumption Alters Promoter Methylation and Expression of Fgf-2 and Fgfr1.
Volume: 24
Issue: 4
Publication
First Author: Ryu H
Year: 2021
Journal: Nat Commun
Title: The molecular dynamics of subdistal appendages in multi-ciliated cells.
Volume: 12
Issue: 1
Pages: 612
Publication
First Author: Riuzzi F
Year: 2017
Journal: Sci Rep
Title: Levels of S100B protein drive the reparative process in acute muscle injury and muscular dystrophy.
Volume: 7
Issue: 1
Pages: 12537
Publication
First Author: LaConti JJ
Year: 2011
Journal: PLoS One
Title: Tissue and serum microRNAs in the Kras(G12D) transgenic animal model and in patients with pancreatic cancer.
Volume: 6
Issue: 6
Pages: e20687
Publication
First Author: Pathare G
Year: 2018
Journal: Sci Rep
Title: Elevated FGF23 Levels in Mice Lacking the Thiazide-Sensitive NaCl cotransporter (NCC).
Volume: 8
Issue: 1
Pages: 3590
Publication
First Author: van Rooijen C
Year: 2012
Journal: Development
Title: Evolutionarily conserved requirement of Cdx for post-occipital tissue emergence.
Volume: 139
Issue: 14
Pages: 2576-83
Publication
First Author: Hart AW
Year: 2000
Journal: Nature
Title: Attenuation of FGF signalling in mouse beta-cells leads to diabetes.
Volume: 408
Issue: 6814
Pages: 864-8
Publication  
First Author: Tang Q
Year: 2024
Journal: Biochem Pharmacol
Title: FGF1(ΔHBS) ameliorates retinal inflammation via suppressing TSPO signal in a type 2 diabetes mouse model.
Volume: 221
Pages: 116039
Publication
First Author: da Silva-Diz V
Year: 2016
Journal: Cancer Res
Title: Cancer Stem-like Cells Act via Distinct Signaling Pathways in Promoting Late Stages of Malignant Progression.
Volume: 76
Issue: 5
Pages: 1245-59
Publication
First Author: Manchado E
Year: 2016
Journal: Nature
Title: A combinatorial strategy for treating KRAS-mutant lung cancer.
Volume: 534
Issue: 7609
Pages: 647-51
Publication
First Author: Li Y
Year: 2017
Journal: Exp Cell Res
Title: Robo signaling regulates the production of cranial neural crest cells.
Volume: 361
Issue: 1
Pages: 73-84
Publication
First Author: Touchberry CD
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy.
Volume: 304
Issue: 8
Pages: E863-73
Publication
First Author: Falardeau J
Year: 2008
Journal: J Clin Invest
Title: Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice.
Volume: 118
Issue: 8
Pages: 2822-31
Publication
First Author: Xiao L
Year: 2004
Journal: J Biol Chem
Title: Stat1 controls postnatal bone formation by regulating fibroblast growth factor signaling in osteoblasts.
Volume: 279
Issue: 26
Pages: 27743-52
Publication
First Author: Nakamura T
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Signals via FGF receptor 2 regulate migration of endothelial cells.
Volume: 289
Issue: 4
Pages: 801-6
Publication
First Author: Peters K
Year: 1993
Journal: Dev Biol
Title: Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis.
Volume: 155
Issue: 2
Pages: 423-30
Publication
First Author: Avivi A
Year: 1993
Journal: FEBS Lett
Title: A novel form of FGF receptor-3 using an alternative exon in the immunoglobulin domain III.
Volume: 330
Issue: 3
Pages: 249-52
Publication
First Author: Yoshida S
Year: 1996
Journal: Nihon Sanka Fujinka Gakkai Zasshi
Title: [Effects of basic fibroblast growth factor on the development of mouse preimplantation embryos].
Volume: 48
Issue: 3
Pages: 170-6
Publication
First Author: García-González D
Year: 2010
Journal: Exp Neurol
Title: Dynamic roles of FGF-2 and Anosmin-1 in the migration of neuronal precursors from the subventricular zone during pre- and postnatal development.
Volume: 222
Issue: 2
Pages: 285-95
Publication
First Author: Munnamalai V
Year: 2012
Journal: J Neurosci
Title: Notch prosensory effects in the Mammalian cochlea are partially mediated by Fgf20.
Volume: 32
Issue: 37
Pages: 12876-84
Publication
First Author: Yaqoob U
Year: 2014
Journal: PLoS One
Title: FGF21 promotes endothelial cell angiogenesis through a dynamin-2 and Rab5 dependent pathway.
Volume: 9
Issue: 5
Pages: e98130
Publication
First Author: Lin L
Year: 2014
Journal: Cancer Discov
Title: A large-scale RNAi-based mouse tumorigenesis screen identifies new lung cancer tumor suppressors that repress FGFR signaling.
Volume: 4
Issue: 10
Pages: 1168-81
Publication
First Author: Fu T
Year: 2014
Journal: Mol Cell Biol
Title: MicroRNA 34a inhibits beige and brown fat formation in obesity in part by suppressing adipocyte fibroblast growth factor 21 signaling and SIRT1 function.
Volume: 34
Issue: 22
Pages: 4130-42
Publication
First Author: Nikolovska K
Year: 2017
Journal: PLoS One
Title: Melanoma Cell Adhesion and Migration Is Modulated by the Uronyl 2-O Sulfotransferase.
Volume: 12
Issue: 1
Pages: e0170054
Publication
First Author: Chang YT
Year: 2015
Journal: Cardiovasc Res
Title: Perlecan heparan sulfate deficiency impairs pulmonary vascular development and attenuates hypoxic pulmonary hypertension.
Volume: 107
Issue: 1
Pages: 20-31
Publication
First Author: Linscott ML
Year: 2019
Journal: PLoS One
Title: TET1 regulates fibroblast growth factor 8 transcription in gonadotropin releasing hormone neurons.
Volume: 14
Issue: 7
Pages: e0220530
Publication
First Author: Justesen S
Year: 2020
Journal: Biochem J
Title: The autocrine role of FGF21 in cultured adipocytes.
Volume: 477
Issue: 13
Pages: 2477-2487
Publication
First Author: Roman-Trufero M
Year: 2020
Journal: Mol Biol Evol
Title: Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3.
Volume: 37
Issue: 7
Pages: 1986-2001
Publication  
First Author: Grońska-Pęski M
Year: 2021
Journal: Neuroscience
Title: FGFR Regulation of Dendrite Elaboration in Adult-born Granule Cells Depends on Intracellular Mediator and Proximity to the Soma.
Volume: 453
Pages: 148-167
Publication
First Author: Ran Q
Year: 2021
Journal: Transplant Cell Ther
Title: Loss of FGFR3 Accelerates Bone Marrow Suppression-Induced Hematopoietic Stem and Progenitor Cell Expansion by Activating FGFR1-ELK1-Cyclin D1 Signaling.
Volume: 27
Issue: 1
Pages: 45.e1-45.e10
Publication
First Author: Liu Z
Year: 2021
Journal: Cell Death Dis
Title: Matrix stiffness modulates hepatic stellate cell activation into tumor-promoting myofibroblasts via E2F3-dependent signaling and regulates malignant progression.
Volume: 12
Issue: 12
Pages: 1134
Publication  
First Author: Takaya K
Year: 2022
Journal: Int J Mol Sci
Title: Fibroblast Growth Factor 7 Suppresses Fibrosis and Promotes Epithelialization during Wound Healing in Mouse Fetuses.
Volume: 23
Issue: 13
Publication  
First Author: Matsiukevich D
Year: 2022
Journal: Front Cardiovasc Med
Title: Fibroblast growth factor receptor signaling in cardiomyocytes is protective in the acute phase following ischemia-reperfusion injury.
Volume: 9
Pages: 1011167
Publication
First Author: Goissis MD
Year: 2023
Journal: PLoS One
Title: Influence of FGF4 and BMP4 on FGFR2 dynamics during the segregation of epiblast and primitive endoderm cells in the pre-implantation mouse embryo.
Volume: 18
Issue: 7
Pages: e0279515
Publication
First Author: Hu MC
Year: 1998
Journal: Mol Cell Biol
Title: FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation.
Volume: 18
Issue: 10
Pages: 6063-74
Publication
First Author: Moore EE
Year: 2005
Journal: Osteoarthritis Cartilage
Title: Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injury-induced osteoarthritis.
Volume: 13
Issue: 7
Pages: 623-31
Publication
First Author: Shimoaka T
Year: 2002
Journal: J Biol Chem
Title: Regulation of osteoblast, chondrocyte, and osteoclast functions by fibroblast growth factor (FGF)-18 in comparison with FGF-2 and FGF-10.
Volume: 277
Issue: 9
Pages: 7493-500
Publication
First Author: Hopper NA
Year: 2006
Journal: Genetics
Title: The adaptor protein soc-1/Gab1 modifies growth factor receptor output in Caenorhabditis elegans.
Volume: 173
Issue: 1
Pages: 163-75
Protein Domain
Type: Family
Description: Fibroblast growth factors (FGFs) [, ]are a family of multifunctional proteins, often referred to as 'promiscuous growth factors' due to their diverse actions on multiple cell types [, ]. FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The function of FGFs in developmental processes include mesoderm induction, anterior-posterior patterning, limb development, and neural induction and development. In mature tissues, they are involved in diverse processes including keratinocyte organisation and wound healing [, , , , , ]. FGF involvement is critical during normal development of both vertebrates and invertebrates, and irregularities in their function leads to a range of developmental defects [, , , ]. Fibroblast growth factors are heparin-binding proteins and interactions with cell-surface-associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs have internal pseudo-threefold symmetry (β-trefoil topology) []. There are currently over 20 different FGF family members that have been identified in mammals, all of which are structurally related signaling molecules [, ]. They exert their effects through four distinct membrane fibroblast growth factor receptors (FGFRs), FGFR1 to FGFR4 [], which belong to the tyrosine kinase superfamily. Upon binding to FGF, the receptors dimerize and their intracellular tyrosine kinase domains become active [].
Protein Domain
Type: Family
Description: Fibroblast growth factors (FGFs) [, ]are a family of multifunctional proteins, often referred to as 'promiscuous growth factors' due to their diverse actions on multiple cell types [, ]. FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The function of FGFs in developmental processes include mesoderm induction, anterior-posterior patterning, limb development, and neural induction and development. In mature tissues, they are involved in diverse processes including keratinocyte organisation and wound healing [, , , , , ]. FGF involvement is critical during normal development of both vertebrates and invertebrates, and irregularities in their function leads to a range of developmental defects [, , , ]. Fibroblast growth factors are heparin-binding proteins and interactions with cell-surface-associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs have internal pseudo-threefold symmetry (β-trefoil topology) []. There are currently over 20 different FGF family members that have been identified in mammals, all of which are structurally related signaling molecules [, ]. They exert their effects through four distinct membrane fibroblast growth factor receptors (FGFRs), FGFR1 to FGFR4 [], which belong to the tyrosine kinase superfamily. Upon binding to FGF, the receptors dimerize and their intracellular tyrosine kinase domains become active [].This entry represents fibroblast growth factor 18 (FGF18), also referred to ZFGF5. FGF18 is required for normal ossification and bone development and stimulates hepatic and intestinal proliferation [, , , ].
Protein Domain
Type: Family
Description: Fibroblast growth factors (FGFs) [, ]are a family of multifunctional proteins, often referred to as 'promiscuous growth factors' due to their diverse actions on multiple cell types [, ]. FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The function of FGFs in developmental processes include mesoderm induction, anterior-posterior patterning, limb development, and neural induction and development. In mature tissues, they are involved in diverse processes including keratinocyte organisation and wound healing [, , , , , ]. FGF involvement is critical during normal development of both vertebrates and invertebrates, and irregularities in their function leads to a range of developmental defects [, , , ]. Fibroblast growth factors are heparin-binding proteins and interactions with cell-surface-associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs have internal pseudo-threefold symmetry (β-trefoil topology) []. There are currently over 20 different FGF family members that have been identified in mammals, all of which are structurally related signaling molecules [, ]. They exert their effects through four distinct membrane fibroblast growth factor receptors (FGFRs), FGFR1 to FGFR4 [], which belong to the tyrosine kinase superfamily. Upon binding to FGF, the receptors dimerize and their intracellular tyrosine kinase domains become active [].This entry represents fibroblast growth factor 11 (FGF11), also known as fibroblast growth factor homologous factor 3. It currently has no known function, but it is thought to be involved in nervous system development and function [].
Publication
First Author: Kenney-Hunt JP
Year: 2006
Journal: Mamm Genome
Title: Quantitative trait loci for body size components in mice.
Volume: 17
Issue: 6
Pages: 526-37
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 724  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1319  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
Publication
First Author: Miraoui H
Year: 2013
Journal: Am J Hum Genet
Title: Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism.
Volume: 92
Issue: 5
Pages: 725-43
Publication
First Author: Eswarakumar VP
Year: 2002
Journal: Development
Title: The IIIc alternative of Fgfr2 is a positive regulator of bone formation.
Volume: 129
Issue: 16
Pages: 3783-93
Publication
First Author: Wheldon LM
Year: 2010
Journal: PLoS One
Title: Critical role of FLRT1 phosphorylation in the interdependent regulation of FLRT1 function and FGF receptor signalling.
Volume: 5
Issue: 4
Pages: e10264
Publication
First Author: Avivi A
Year: 1992
Journal: Oncogene
Title: Promoter region of the murine fibroblast growth factor receptor 2 (bek/KGFR) gene.
Volume: 7
Issue: 10
Pages: 1957-62
Publication
First Author: Ding BS
Year: 2014
Journal: Nature
Title: Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis.
Volume: 505
Issue: 7481
Pages: 97-102
Publication
First Author: Huang X
Year: 2006
Journal: Mol Carcinog
Title: Forced expression of hepatocyte-specific fibroblast growth factor 21 delays initiation of chemically induced hepatocarcinogenesis.
Volume: 45
Issue: 12
Pages: 934-42
Publication
First Author: Yuan G
Year: 2021
Journal: Nature
Title: Elevated NSD3 histone methylation activity drives squamous cell lung cancer.
Volume: 590
Issue: 7846
Pages: 504-508
Publication
First Author: Li H
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype.
Volume: 300
Issue: 3
Pages: E508-17
Publication
First Author: Sun P
Year: 2020
Journal: Circ Res
Title: Endothelium-Targeted Deletion of microRNA-15a/16-1 Promotes Poststroke Angiogenesis and Improves Long-Term Neurological Recovery.
Volume: 126
Issue: 8
Pages: 1040-1057
Publication
First Author: Wu S
Year: 2013
Journal: J Biol Chem
Title: Increased expression of fibroblast growth factor 21 (FGF21) during chronic undernutrition causes growth hormone insensitivity in chondrocytes by inducing leptin receptor overlapping transcript (LEPROT) and leptin receptor overlapping transcript-like 1 (LEPROTL1) expression.
Volume: 288
Issue: 38
Pages: 27375-83
Publication
First Author: Reed JR
Year: 2012
Journal: PLoS One
Title: Fibroblast growth factor receptor 1 activation in mammary tumor cells promotes macrophage recruitment in a CX3CL1-dependent manner.
Volume: 7
Issue: 9
Pages: e45877
Publication
First Author: Yang M
Year: 2012
Journal: PLoS One
Title: Liraglutide increases FGF-21 activity and insulin sensitivity in high fat diet and adiponectin knockdown induced insulin resistance.
Volume: 7
Issue: 11
Pages: e48392
Publication  
First Author: Schmid A
Year: 2019
Journal: Mol Cell Endocrinol
Title: Evidence of functional bile acid signaling pathways in adipocytes.
Volume: 483
Pages: 1-10
Publication  
First Author: Lu W
Year: 2021
Journal: Cancer Lett
Title: FGF21 in obesity and cancer: New insights.
Volume: 499
Pages: 5-13
Publication
First Author: Ornitz DM
Year: 1996
Journal: J Biol Chem
Title: Receptor specificity of the fibroblast growth factor family.
Volume: 271
Issue: 25
Pages: 15292-7
Publication
First Author: Beer HD
Year: 2005
Journal: Oncogene
Title: The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair.
Volume: 24
Issue: 34
Pages: 5269-77
Protein
Organism: Mus musculus/domesticus
Length: 243  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 225  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 69  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 221  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: false