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Search results 701 to 778 out of 778 for Smn1

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Strain
MGI:5495411 | FVB.Cg-Grm7<Tg(SMN2)89Ahmb> Smn1<tm1Msd> Tg(SMN1*A2G)2023Ahmb/2J
Attribute String: congenic, mutant strain, transgenic, targeted mutation
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Strain
MGI:5495460 | B6.Cg-Grm7<Tg(SMN2)89Ahmb> Smn1<tm1Msd> Tg(SMN1*A2G)2023Ahmb/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:3521946 | FVB.Cg-Grm7<Tg(SMN2)89Ahmb> Smn1<tm1Msd> Tg(SMN1*A2G)2023Ahmb/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Publication
17318264 | J:120738
First Author: Avila AM
Year: 2007
Journal: J Clin Invest
Title: Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy.
Volume: 117
Issue: 3
Pages: 659-71
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Genotype
Genotype
Symbol: Smn1/Smn1 Tg(SMN1*A2G)2023Ahmb/Tg(SMN1*A2G)2023Ahmb Grm7/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1 Tg(SMN1*A2G)2023Ahmb/? Grm7/Grm7
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1 Tg(SMN1*A2G)2023Ahmb/? Tg(SMN2*A111G)591Ahmb/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Protein
Q8BHE1
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: false
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Protein
B1AVP5
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
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Protein
E9QA54
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: true
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Protein
E9PZ44
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: true
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Publication
17023415 | -
First Author: Carissimi C
Year: 2006
Journal: J Biol Chem
Title: Gemin8 is required for the architecture and function of the survival motor neuron complex.
Volume: 281
Issue: 48
Pages: 37009-16
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Protein Domain
IPR034754 | GEMIN8
Type: Family
Description: GEMIN8 proteins are found in the nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies themselves. They are also found in the cytoplasm []. The family is part of the SMN (survival motor neurone) complex that plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. GEMIN8 binds directly to SMN1 and mediates the interaction of the GEMIN6-GEMIN7 heterodimer [].
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Allele
Smg6<Tg(SMN1*delta5)1Pks> | MGI:5493450
Name: SMG6 nonsense mediated mRNA decay factor; transgene insertion 1, Nick Parkinson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:3846837 | B6.Cg-Smn1<tm2Mrph>/J
Attribute String: targeted mutation, congenic
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Strain
MGI:5655838 | B6;129-Smn1<tm2Mrph>/J
Attribute String: targeted mutation, mutant stock
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Strain
MGI:3846841 | FVB.Cg-Smn1<tm2Mrph>/J
Attribute String: congenic, targeted mutation
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Allele
Smn1<tm2Cdid> | MGI:5290070
Name: survival motor neuron 1; targeted mutation 2, Christine DiDonato
Allele Type: Targeted
Attribute String: Hypomorph
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Strain
MGI:6771180 | C57BL/6J-Smn1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: involves: 129S6/SvEvTac * C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1 Tg(SMN1*A2G)2023Ahmb/? Tg(SMN2*A111G)588Ahmb/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Allele
Tg(SMN2-SMN1*Q282A)2Ahmb | MGI:6189119
Name: transgene insertion 2, Arthur H M Burghes
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:5493453 | STOCK Smg6<Tg(SMN1*delta5)1Pks>/H
Attribute String: mutant stock, transgenic
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Allele
Tg(SMN1*E134K)1Tlbt | MGI:5493441
Name: transgene insertion 1, Kevin Talbot
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:5493444 | B6;CBA-Tg(SMN1*E134K)1Tlbt/H
Attribute String: mutant stock, transgenic
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Publication
- | J:197598
     
First Author: Parkinson N
Year: 2012
Journal: Personal Communication to K. Pickford at Harwell
Title: Personal Communication: SMN E134K transgene
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: involves: 129 * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smg6/Smg6<+>
Background: involves: C57BL/6 * CBA * FVB/N
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smg6/Smg6
Background: involves: C57BL/6 * CBA * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Allele
Tg(SMN1-SMN2*)16Cll | MGI:5490785
Name: transgene insertion 16, Christian L Lorson
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Smn1<tm4(SMN2)Mrph> | MGI:3794200
Name: survival motor neuron 1; targeted mutation 4, Andrew Murphy
Allele Type: Targeted
Attribute String: Humanized sequence
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Strain
MGI:3811193 | B6.129-Smn1<tm4(SMN2)Mrph>/J
Attribute String: congenic, targeted mutation
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Strain
MGI:3811192 | FVB.129(B6)-Smn1<tm4(SMN2)Mrph>/J
Attribute String: congenic
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Strain
MGI:5655840 | B6;129-Smn1<tm4(SMN2)Mrph>/J
Attribute String: mutant stock, targeted mutation
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Strain
MGI:6379739 | STOCK Smn1<tm2Cdid> Tg(SMN2)1Cdid/J
Attribute String: targeted mutation, transgenic, mutant stock
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1<+>
Background: involves: 129S6/SvEvTac * C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
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Publication
12692162 | J:83006
First Author: van den Berg L
Year: 2003
Journal: J Hered
Title: Isolation and characterization of the canine serotonin receptor 1A gene (htr1A).
Volume: 94
Issue: 1
Pages: 49-56
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Publication
28193854 | J:241214
First Author: Woo CJ
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy.
Volume: 114
Issue: 8
Pages: E1509-E1518
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Strain
MGI:6199468 | FVB.Cg-Grm7<Tg(SMN2)89Ahmb> Smn1<tm1Msd> Tg(SMN2-SMN1*T274I)5Ahmb/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:6199490 | FVB.Cg-Grm7<Tg(SMN2)89Ahmb> Smn1<tm1Msd> Tg(SMN2-SMN1*I116F)11Ahmb/J
Attribute String: transgenic, targeted mutation, mutant strain, congenic
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Strain
MGI:5494997 | STOCK Grm7<Tg(SMN2)89Ahmb> Smg6<Tg(SMN1*delta5)1Pks> Smn1<tm1Msd>/H
Attribute String: targeted mutation, transgenic, mutant stock
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Strain
MGI:6199464 | STOCK Grm7<Tg(SMN2)89Ahmb> Smn1<tm1Msd> Tg(SMN2-SMN1*D44V)10Ahmb/J
Attribute String: transgenic, targeted mutation, mutant stock
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Strain
MGI:5435095 | B6;129-Smn1<tm5(Smn1/SMN2)Mrph>/J
Attribute String: targeted mutation, mutant stock
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Strain
MGI:3811196 | B6.129-Smn1<tm5(Smn1/SMN2)Mrph>/J
Attribute String: congenic, targeted mutation, mutant strain
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Strain
MGI:3811194 | FVB.129(B6)-Smn1<tm5(Smn1/SMN2)Mrph>/J
Attribute String: targeted mutation, congenic, mutant strain
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: B6.129-Smn1/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: FVB.129(B6)-Smn1/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1<+>
Background: involves: 129S6/SvEvTac * C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
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Publication
11528396 | J:71530
First Author: Grohmann K
Year: 2001
Journal: Nat Genet
Title: Mutations in the gene encoding immunoglobulin mu-binding protein 2 cause spinal muscular atrophy with respiratory distress type 1.
Volume: 29
Issue: 1
Pages: 75-7
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Publication
20884664 | J:166545
First Author: Jodelka FM
Year: 2010
Journal: Hum Mol Genet
Title: A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2.
Volume: 19
Issue: 24
Pages: 4906-17
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Publication
26672899 | J:231836
 
First Author: Hasegawa M
Year: 2016
Journal: Neurosci Res
Title: Analysis of RNA metabolism in peripheral WBCs of TDP-43 KI mice identifies novel biomarkers of ALS.
Volume: 106
Pages: 12-22
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Publication
11161782 | J:66991
First Author: Kelter AR
Year: 2000
Journal: Genomics
Title: The transcription factor-like nuclear regulator (TFNR) contains a novel 55-amino-acid motif repeated nine times and maps closely to SMN1.
Volume: 70
Issue: 3
Pages: 315-26
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Strain
MGI:6199466 | STOCK Grm7<Tg(SMN2)89Ahmb> Tg(SMN2-SMN1*Q282A)2Ahmb Smn1<tm1Msd>/J
Attribute String: targeted mutation, transgenic, mutant stock
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Strain
MGI:6189121 | FVB.Cg-Tg(SMN2*A111G)588Ahmb Tg(SMN2-SMN1*Q282A)2Ahmb Smn1<tm1Msd>/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:5562870 | STOCK Grm7<Tg(SMN2)89Ahmb> Smn1<tm1Msd> Tg(SMN1-SMN2*)16Cll/CllJ
Attribute String: mutant stock, targeted mutation, transgenic
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Strain
MGI:5494266 | STOCK Grm7<Tg(SMN2)89Ahmb> Smn1<tm1Msd> Tg(SMN1*E134K)1Tlbt/H
Attribute String: mutant stock, targeted mutation, transgenic
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Strain
MGI:5496050 | B6.Cg-Grm7<Tg(SMN2)89Ahmb> Smn1<tm1Msd>/Smn1<tm5(Smn1/SMN2)Mrph>/J
Attribute String: targeted mutation, transgenic, mutant strain, congenic
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Strain
MGI:5496054 | FVB.Cg-Grm7<Tg(SMN2)89Ahmb> Smn1<tm1Msd>/Smn1<tm5(Smn1/SMN2)Mrph>/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:6384252 | B6.Cg-Tia1<tm1Andp> Smn1<tm5(Smn1/SMN2)Mrph>/RnsMmjax
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:3846830 | B6.Cg-Smn1<tm3(SMN2/Smn1)Mrph>/J
Attribute String: targeted mutation, congenic
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Strain
MGI:3846836 | FVB.Cg-Smn1<tm3(SMN2/Smn1)Mrph>/J
Attribute String: congenic, targeted mutation
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Strain
MGI:5655839 | B6;129-Smn1<tm3(SMN2/Smn1)Mrph>/J
Attribute String: mutant stock, targeted mutation
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: involves: 129S6/SvEvTac * C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smn1/Smn1 Tg(SMN1-SMN2*)16Cll/? Grm7/Grm7
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Publication
11726560 | J:73189
First Author: DiDonato CJ
Year: 2001
Journal: Hum Mol Genet
Title: Regulation of murine survival motor neuron (Smn) protein levels by modifying Smn exon 7 splicing.
Volume: 10
Issue: 23
Pages: 2727-36
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Strain
MGI:3794303 | STOCK Grm7<Tg(SMN2)89Ahmb> Smn1<tm3(SMN2/Smn1)Mrph> Tg(SMN2*delta7)4299Ahmb/J
Attribute String: targeted mutation, transgenic, mutant stock
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Strain
MGI:5496283 | STOCK Grm7<Tg(SMN2)89Ahmb> Smn1<tm3(SMN2/Smn1)Mrph>/J
Attribute String: mutant stock, targeted mutation, transgenic
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Genotype
Genotype
Symbol: Smn1/Smn1
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
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Strain
MGI:5438564 | STOCK Grm7<Tg(SMN2)89Ahmb> Smn1<tm3(SMN2/Smn1)Mrph> Tg(CAG-cre/Esr1*)5Amc Tg(SMN2*delta7)4299Ahmb/J
Attribute String: mutant stock, targeted mutation, transgenic
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Publication
- | J:169366
     
First Author: MouseBookTM
Year: 2005
Journal: Unpublished
Title: Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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