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Search results 101 to 200 out of 211 for Sharpin

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Hits by Pathway

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:7567653
Assay Type: RT-PCR
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:7567664
Age: embryonic day 13.5
Specimen Label: head
Detected: true
Specimen Num: 2
•
•
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:7567653
Assay Type: RT-PCR
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:7567669
Age: embryonic day 13.5
Specimen Label: head
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7567653
Assay Type: RT-PCR
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624721
Stage: TS21
Assay Id: MGI:7567664
Age: embryonic day 13.5
Specimen Label: gut
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7567653
Assay Type: RT-PCR
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624721
Stage: TS21
Assay Id: MGI:7567669
Age: embryonic day 13.5
Specimen Label: gut
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7567659
Assay Type: RNA in situ
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3288322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7567674
Age: embryonic day 14.5
Note: Expression in otic epithelium.
Specimen Label: 3D Sipl1 inner ear
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9351
Specimen Label: GUDMAP:9351
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7567659
Assay Type: RNA in situ
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7567674
Age: embryonic day 14.5
Note: Expression in spiral ganglion.
Specimen Label: 3D Sipl1 inner ear
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2853323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9351
Specimen Label: GUDMAP:9351
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9351
Specimen Label: GUDMAP:9351
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9351
Specimen Label: GUDMAP:9351
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1869223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9351
Specimen Label: GUDMAP:9351
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7567659
Assay Type: RNA in situ
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Pattern: Ubiquitous
Stage: TS21
Assay Id: MGI:7567674
Age: embryonic day 13.5
Specimen Label: 3C Sipl1 overview
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9351
Specimen Label: GUDMAP:9351
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9351
Specimen Label: GUDMAP:9351
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9351
Specimen Label: GUDMAP:9351
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9351
Specimen Label: GUDMAP:9351
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9351
Specimen Label: GUDMAP:9351
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7567659
Assay Type: RNA in situ
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3559221
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7567674
Age: embryonic day 13.5
Note: Co-expression with Eya1 and Rbck1 in developing nephrons in outer region of kidney.
Specimen Label: 3C Sipl1 kidney
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9351
Specimen Label: GUDMAP:9351
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9351
Specimen Label: GUDMAP:9351
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4879236
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540954
Age: embryonic day 15.5
Image: GUDMAP:9350
Specimen Label: GUDMAP:9350
Detected: true
Specimen Num: 1
•
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Publication
29695863 | J:261640
First Author: Peltzer N
Year: 2018
Journal: Nature
Title: LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.
Volume: 557
Issue: 7703
Pages: 112-117
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Publication
26321245 | J:325817
First Author: Chien SJ
Year: 2015
Journal: Exp Mol Pathol
Title: The pathogenesis of chronic eosinophilic esophagitis in SHARPIN-deficient mice.
Volume: 99
Issue: 3
Pages: 460-7
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Publication
24821972 | J:228785
First Author: Berger SB
Year: 2014
Journal: J Immunol
Title: Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice.
Volume: 192
Issue: 12
Pages: 5476-80
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Publication
30038386 | J:296048
First Author: Sharma BR
Year: 2019
Journal: Cell Death Differ
Title: Innate immune adaptor MyD88 deficiency prevents skin inflammation in SHARPIN-deficient mice.
Volume: 26
Issue: 4
Pages: 741-750
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Publication
16984263 | J:135844
First Author: HogenEsch H
Year: 2006
Journal: Exp Dermatol
Title: Expression of chitinase-like proteins in the skin of chronic proliferative dermatitis (cpdm/cpdm) mice.
Volume: 15
Issue: 10
Pages: 808-14
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Publication
10201521 | J:54070
First Author: Schön MP
Year: 1999
Journal: J Invest Dermatol
Title: Animal models of psoriasis - what can we learn from them?
Volume: 112
Issue: 4
Pages: 405-10
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Publication
32269263 | J:287543
First Author: Laurien L
Year: 2020
Journal: Nat Commun
Title: Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation.
Volume: 11
Issue: 1
Pages: 1747
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Publication
23942237 | J:201885
First Author: Sasaki Y
Year: 2013
Journal: EMBO J
Title: Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.
Volume: 32
Issue: 18
Pages: 2463-76
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Publication
27810922 | J:237520
First Author: Zinngrebe J
Year: 2016
Journal: J Exp Med
Title: --LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation.
Volume: 213
Issue: 12
Pages: 2671-2689
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Publication
26216893 | J:324561
First Author: Douglas T
Year: 2015
Journal: J Immunol
Title: The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice.
Volume: 195
Issue: 5
Pages: 2365-73
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Publication
22607974 | J:188020
First Author: Damgaard RB
Year: 2012
Journal: Mol Cell
Title: The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.
Volume: 46
Issue: 6
Pages: 746-58
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Publication
34752416 | J:325548
 
First Author: Chun N
Year: 2021
Journal: JCI Insight
Title: T cell-derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death.
Volume: 6
Issue: 24
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Publication
31101885 | J:288313
First Author: Patel S
Year: 2020
Journal: Cell Death Differ
Title: RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases.
Volume: 27
Issue: 1
Pages: 161-175
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Publication
25284787 | J:238820
First Author: Peltzer N
Year: 2014
Journal: Cell Rep
Title: HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death.
Volume: 9
Issue: 1
Pages: 153-65
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Publication
25599590 | J:219574
   
First Author: MacDuff DA
Year: 2015
Journal: Elife
Title: Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection.
Volume: 4
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Publication
9873228 | J:52422
First Author: HogenEsch H
Year: 1999
Journal: Pathobiology
Title: Changes in keratin and filaggrin expression in the skin of chronic proliferative dermatitis (cpdm) mutant mice.
Volume: 67
Issue: 1
Pages: 45-50
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Publication
24461064 | J:215707
First Author: Takiuchi T
Year: 2014
Journal: Genes Cells
Title: Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.
Volume: 19
Issue: 3
Pages: 254-72
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Publication
30254289 | J:267737
First Author: Taraborrelli L
Year: 2018
Journal: Nat Commun
Title: LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L.
Volume: 9
Issue: 1
Pages: 3910
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Publication
23951545 | J:207797
 
First Author: Liu S
Year: 2013
Journal: Elife
Title: MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades.
Volume: 2
Pages: e00785
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Publication
17429444 | J:121548
First Author: Gudjonsson JE
Year: 2007
Journal: J Invest Dermatol
Title: Mouse models of psoriasis.
Volume: 127
Issue: 6
Pages: 1292-308
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Publication
30755793 | J:341418
   
First Author: Holbrook J
Year: 2019
Journal: F1000Res
Title: Tumour necrosis factor signalling in health and disease.
Volume: 8
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Publication
29203883 | J:265712
First Author: Dziedzic SA
Year: 2018
Journal: Nat Cell Biol
Title: ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC.
Volume: 20
Issue: 1
Pages: 58-68
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Publication
19208628 | J:148808
First Author: Sawallisch C
Year: 2009
Journal: J Biol Chem
Title: The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.
Volume: 284
Issue: 14
Pages: 9225-36
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Publication
- | J:30359
       
First Author: Sundberg JP (ed.)
Year: 1994
Title: Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools
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Publication
34157307 | J:308817
First Author: Fu Y
Year: 2021
Journal: Mol Cell
Title: OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin.
Volume: 81
Issue: 15
Pages: 3187-3204.e7
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
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First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
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First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
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First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Interaction Experiment
Liang Y (2011)
Description: SHARPIN negatively associates with TRAF2-mediated NFB activation.
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Interaction Experiment
Rantala JK (2011)
Description: SHARPIN is an endogenous inhibitor of 1-integrin activation.
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GXD Expression
GXD Expression
 
Probe: MGI:7567660
Assay Type: RNA in situ
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3559221
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7567675
Age: embryonic day 13.5
Note: Co-expression with Eya1 and Sharpin in developing nephrons in outer region of kidney.
Specimen Label: 3C Rbck1 kidney
Detected: true
Specimen Num: 2
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Interaction Experiment
Ikeda F (2011)
Description: SHARPIN forms a linear ubiquitin ligase complex regulating NF-B activity and apoptosis.
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Interaction Experiment
Fujita H (2018)
Description: Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization.
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Protein Domain
IPR031912 | Sharpin_PH
Type: Domain
Description: This PH domain is found at the N terminus of sharpin and is involved in dimerisation. Sharpin is part of the LUBAC complex, a large multi-protein E3 ubiquitin ligase complex that catalyses the formation of linear ubiquitin chains and regulates immune and apoptopic signalling pathways [].
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Publication
22549881 | -
First Author: Stieglitz B
Year: 2012
Journal: J Biol Chem
Title: Structural analysis of SHARPIN, a subunit of a large multi-protein E3 ubiquitin ligase, reveals a novel dimerization function for the pleckstrin homology superfold.
Volume: 287
Issue: 25
Pages: 20823-9
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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