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Search results 201 to 300 out of 460 for Grm7

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:5001974
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542528
Age: embryonic day 15.5
Image: GUDMAP:8471
Specimen Label: GUDMAP:8471
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
       
Assay Type: In situ reporter (knock in)
Annotation Date: 2006-07-27
Strength: Absent
Sex: Male
Emaps: EMAPS:1868228
Stage: TS28
Assay Id: MGI:3639195
Age: postnatal day 53
Specimen Label: Mouse 101621
Detected: false
Specimen Num: 27
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Publication
11584003 | J:73174
First Author: Perroy J
Year: 2001
Journal: J Biol Chem
Title: The C terminus of the metabotropic glutamate receptor subtypes 2 and 7 specifies the receptor signaling pathways.
Volume: 276
Issue: 49
Pages: 45800-5
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Publication
12065412 | J:114768
First Author: Perroy J
Year: 2002
Journal: EMBO J
Title: PICK1 is required for the control of synaptic transmission by the metabotropic glutamate receptor 7.
Volume: 21
Issue: 12
Pages: 2990-9
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Publication
27111068 | J:244184
First Author: Seo J
Year: 2016
Journal: PLoS One
Title: Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene.
Volume: 11
Issue: 4
Pages: e0154390
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Publication
29982416 | J:265815
First Author: Iyer CC
Year: 2018
Journal: Hum Mol Genet
Title: Mild SMN missense alleles are only functional in the presence of SMN2 in mammals.
Volume: 27
Issue: 19
Pages: 3404-3416
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Publication
33084884 | J:301445
First Author: McGovern VL
Year: 2021
Journal: Hum Mol Genet
Title: Intragenic complementation of amino and carboxy terminal SMN missense mutations can rescue Smn null mice.
Volume: 29
Issue: 21
Pages: 3493-3503
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Publication
19010792 | J:143540
First Author: Meyer K
Year: 2009
Journal: Hum Mol Genet
Title: Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation.
Volume: 18
Issue: 3
Pages: 546-55
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Publication
20832308 | J:231141
First Author: Voigt T
Year: 2010
Journal: Neuromuscul Disord
Title: Ultrastructural changes in diaphragm neuromuscular junctions in a severe mouse model for Spinal Muscular Atrophy and their prevention by bifunctional U7 snRNA correcting SMN2 splicing.
Volume: 20
Issue: 11
Pages: 744-52
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Publication
25692239 | J:231140
First Author: Huo Q
Year: 2014
Journal: RNA Biol
Title: Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: evidence for involvement of splicing regulatory proteins.
Volume: 11
Issue: 11
Pages: 1430-46
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Publication
26621405 | J:231139
 
First Author: Neve A
Year: 2016
Journal: Mol Cell Neurosci
Title: Central and peripheral defects in motor units of the diaphragm of spinal muscular atrophy mice.
Volume: 70
Pages: 30-41
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Publication
37064776 | J:341749
 
First Author: Chen TH
Year: 2023
Journal: Mol Ther Nucleic Acids
Title: MiR34 contributes to spinal muscular atrophy and AAV9-mediated delivery of MiR34a ameliorates the motor deficits in SMA mice.
Volume: 32
Pages: 144-160
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Publication
10655541 | J:60592
First Author: Monani UR
Year: 2000
Journal: Hum Mol Genet
Title: The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy.
Volume: 9
Issue: 3
Pages: 333-9
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Publication
18641645 | J:139513
First Author: Bertaso F
Year: 2008
Journal: Nat Neurosci
Title: PICK1 uncoupling from mGluR7a causes absence-like seizures.
Volume: 11
Issue: 8
Pages: 940-8
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Publication
20097677 | J:158347
First Author: Riessland M
Year: 2010
Journal: Hum Mol Genet
Title: SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy.
Volume: 19
Issue: 8
Pages: 1492-506
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Publication
35688133 | J:326049
First Author: Marasco LE
Year: 2022
Journal: Cell
Title: Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy.
Volume: 185
Issue: 12
Pages: 2057-2070.e15
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Publication
34825141 | J:348130
First Author: Buettner JM
Year: 2021
Journal: iScience
Title: Central synaptopathy is the most conserved feature of motor circuit pathology across spinal muscular atrophy mouse models.
Volume: 24
Issue: 11
Pages: 103376
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Publication
36291733 | J:348133
 
First Author: Franco-Espin J
Year: 2022
Journal: Biomolecules
Title: SMN Is Physiologically Downregulated at Wild-Type Motor Nerve Terminals but Aggregates Together with Neurofilaments in SMA Mouse Models.
Volume: 12
Issue: 10
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Publication
27488123 | J:237935
First Author: Miller N
Year: 2016
Journal: Hum Mol Genet
Title: Motor neuron mitochondrial dysfunction in spinal muscular atrophy.
Volume: 25
Issue: 16
Pages: 3395-3406
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Publication
21708901 | J:175452
First Author: Sleigh JN
Year: 2011
Journal: Dis Model Mech
Title: The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy.
Volume: 4
Issue: 4
Pages: 457-67
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Publication
21396450 | J:174332
First Author: Gogliotti RG
Year: 2011
Journal: Neurobiol Dis
Title: Characterization of a commonly used mouse model of SMA reveals increased seizure susceptibility and heightened fear response in FVB/N mice.
Volume: 43
Issue: 1
Pages: 142-51
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Publication
28463115 | J:258135
   
First Author: O'Hern PJ
Year: 2017
Journal: Elife
Title: Decreased microRNA levels lead to deleterious increases in neuronal M2 muscarinic receptors in Spinal Muscular Atrophy models.
Volume: 6
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Publication
24301677 | J:208449
First Author: Hunter G
Year: 2014
Journal: Hum Mol Genet
Title: SMN-dependent intrinsic defects in Schwann cells in mouse models of spinal muscular atrophy.
Volume: 23
Issue: 9
Pages: 2235-50
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Publication
21840928 | J:176892
First Author: Mutsaers CA
Year: 2011
Journal: Hum Mol Genet
Title: Reversible molecular pathology of skeletal muscle in spinal muscular atrophy.
Volume: 20
Issue: 22
Pages: 4334-44
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Publication
12515823 | J:81238
First Author: Monani UR
Year: 2003
Journal: J Cell Biol
Title: A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy.
Volume: 160
Issue: 1
Pages: 41-52
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Publication
18178576 | J:131663
First Author: Gavrilina TO
Year: 2008
Journal: Hum Mol Genet
Title: Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect.
Volume: 17
Issue: 8
Pages: 1063-75
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Publication
19329542 | J:148541
First Author: Workman E
Year: 2009
Journal: Hum Mol Genet
Title: A SMN missense mutation complements SMN2 restoring snRNPs and rescuing SMA mice.
Volume: 18
Issue: 12
Pages: 2215-29
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Publication
22306031 | J:181868
 
First Author: Fulceri F
Year: 2012
Journal: Brain Res
Title: Motor neuron pathology and behavioral alterations at late stages in a SMA mouse model.
Volume: 1442
Pages: 66-75
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Publication
21085654 | J:166818
First Author: Ling KK
Year: 2010
Journal: PLoS One
Title: Synaptic defects in the spinal and neuromuscular circuitry in a mouse model of spinal muscular atrophy.
Volume: 5
Issue: 11
Pages: e15457
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Publication
21968514 | J:178856
First Author: Ling KK
Year: 2012
Journal: Hum Mol Genet
Title: Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy.
Volume: 21
Issue: 1
Pages: 185-95
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Publication
28178525 | J:256200
First Author: Rodriguez-Muela N
Year: 2017
Journal: Cell Rep
Title: Single-Cell Analysis of SMN Reveals Its Broader Role in Neuromuscular Disease.
Volume: 18
Issue: 6
Pages: 1484-1498
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Publication
18603534 | J:138317
First Author: McGovern VL
Year: 2008
Journal: Hum Mol Genet
Title: Embryonic motor axon development in the severe SMA mouse.
Volume: 17
Issue: 18
Pages: 2900-9
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Publication
22037760 | J:183557
First Author: Ruggiu M
Year: 2012
Journal: Mol Cell Biol
Title: A role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophy.
Volume: 32
Issue: 1
Pages: 126-38
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Publication
23029491 | J:191961
First Author: Lee AJ
Year: 2012
Journal: PLoS One
Title: Limited phenotypic effects of selectively augmenting the SMN protein in the neurons of a mouse model of severe spinal muscular atrophy.
Volume: 7
Issue: 9
Pages: e46353
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Publication
25859009 | J:223348
First Author: Gombash SE
Year: 2015
Journal: Hum Mol Genet
Title: SMN deficiency disrupts gastrointestinal and enteric nervous system function in mice.
Volume: 24
Issue: 13
Pages: 3847-60
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Publication
23390132 | J:194969
First Author: Cobb MS
Year: 2013
Journal: Hum Mol Genet
Title: Development and characterization of an SMN2-based intermediate mouse model of Spinal Muscular Atrophy.
Volume: 22
Issue: 9
Pages: 1843-55
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Publication
24781211 | J:213594
First Author: Osman EY
Year: 2014
Journal: Hum Mol Genet
Title: Morpholino antisense oligonucleotides targeting intronic repressor Element1 improve phenotype in SMA mouse models.
Volume: 23
Issue: 18
Pages: 4832-45
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Publication
15703193 | J:97103
First Author: Le TT
Year: 2005
Journal: Hum Mol Genet
Title: SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN.
Volume: 14
Issue: 6
Pages: 845-57
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Publication
21681521 | J:176036
First Author: Dale JM
Year: 2011
Journal: Acta Neuropathol
Title: The spinal muscular atrophy mouse model, SMAΔ7, displays altered axonal transport without global neurofilament alterations.
Volume: 122
Issue: 3
Pages: 331-41
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Publication
28062667 | J:241426
First Author: Khairallah MT
Year: 2017
Journal: Hum Mol Genet
Title: SMN deficiency negatively impacts red pulp macrophages and spleen development in mouse models of spinal muscular atrophy.
Volume: 26
Issue: 5
Pages: 932-941
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Publication
26931466 | J:348120
First Author: Zhao X
Year: 2016
Journal: Hum Mol Genet
Title: Pharmacokinetics, pharmacodynamics, and efficacy of a small-molecule SMN2 splicing modifier in mouse models of spinal muscular atrophy.
Volume: 25
Issue: 10
Pages: 1885-1899
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Publication
36130491 | J:329300
First Author: Tisdale S
Year: 2022
Journal: Cell Rep
Title: SMN controls neuromuscular junction integrity through U7 snRNP.
Volume: 40
Issue: 12
Pages: 111393
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Publication
34425216 | J:348122
 
First Author: Kray KM
Year: 2021
Journal: Neurobiol Dis
Title: Dual SMN inducing therapies can rescue survival and motor unit function in symptomatic ∆7SMA mice.
Volume: 159
Pages: 105488
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Publication
33060681 | J:348123
First Author: Ando S
Year: 2020
Journal: Sci Rep
Title: Discovery of a CNS penetrant small molecule SMN2 splicing modulator with improved tolerability for spinal muscular atrophy.
Volume: 10
Issue: 1
Pages: 17472
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Publication
34888619 | J:348131
First Author: Wang J
Year: 2022
Journal: Hum Mol Genet
Title: Antisense oligonucleotides targeting the SMN2 promoter region enhance SMN2 expression in spinal muscular atrophy cell lines and mouse model.
Volume: 31
Issue: 10
Pages: 1635-1650
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Publication
32612161 | J:348126
First Author: Berciano MT
Year: 2020
Journal: Sci Rep
Title: Nusinersen ameliorates motor function and prevents motoneuron Cajal body disassembly and abnormal poly(A) RNA distribution in a SMA mouse model.
Volume: 10
Issue: 1
Pages: 10738
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Publication
21904622 | J:348121
First Author: Kobayashi DT
Year: 2011
Journal: PLoS One
Title: Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analyses.
Volume: 6
Issue: 8
Pages: e24269
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Publication
34542403 | J:348127
   
First Author: Abiusi E
Year: 2021
Journal: Elife
Title: SMA-miRs (miR-181a-5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples.
Volume: 10
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Publication
36603028 | J:348124
First Author: Boido M
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Agonist of growth hormone-releasing hormone improves the disease features of spinal muscular atrophy mice.
Volume: 120
Issue: 2
Pages: e2216814120
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Publication
36089582 | J:348132
First Author: Woschitz V
Year: 2022
Journal: Skelet Muscle
Title: Mouse models of SMA show divergent patterns of neuronal vulnerability and resilience.
Volume: 12
Issue: 1
Pages: 22
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Publication
36996170 | J:343015
First Author: Arbab M
Year: 2023
Journal: Science
Title: Base editing rescue of spinal muscular atrophy in cells and in mice.
Volume: 380
Issue: 6642
Pages: eadg6518
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Publication
35551393 | J:348135
First Author: Comley LH
Year: 2022
Journal: Hum Mol Genet
Title: Motor unit recovery following Smn restoration in mouse models of spinal muscular atrophy.
Volume: 31
Issue: 18
Pages: 3107-3119
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Publication
37365234 | J:348136
First Author: Lumpkin CJ
Year: 2023
Journal: Sci Rep
Title: Evaluation of the orally bioavailable 4-phenylbutyrate-tethered trichostatin A analogue AR42 in models of spinal muscular atrophy.
Volume: 13
Issue: 1
Pages: 10374
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Publication
30233310 | J:348129
 
First Author: Schellino R
Year: 2018
Journal: Front Mol Neurosci
Title: Pharmacological c-Jun NH(2)-Terminal Kinase (JNK) Pathway Inhibition Reduces Severity of Spinal Muscular Atrophy Disease in Mice.
Volume: 11
Pages: 308
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Publication
37957344 | J:348138
First Author: Valsecchi V
Year: 2023
Journal: Commun Biol
Title: SMN deficiency perturbs monoamine neurotransmitter metabolism in spinal muscular atrophy.
Volume: 6
Issue: 1
Pages: 1155
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Publication
37834400 | J:348137
 
First Author: Cadile F
Year: 2023
Journal: Int J Mol Sci
Title: Diaphragm Fatigue in SMNΔ7 Mice and Its Molecular Determinants: An Underestimated Issue.
Volume: 24
Issue: 19
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Publication
30842449 | J:275605
First Author: Ohuchi K
Year: 2019
Journal: Sci Rep
Title: Notch Signaling Mediates Astrocyte Abnormality in Spinal Muscular Atrophy Model Systems.
Volume: 9
Issue: 1
Pages: 3701
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Publication
26258776 | J:238913
First Author: Luchetti A
Year: 2015
Journal: Int J Mol Sci
Title: A Perturbed MicroRNA Expression Pattern Characterizes Embryonic Neural Stem Cells Derived from a Severe Mouse Model of Spinal Muscular Atrophy (SMA).
Volume: 16
Issue: 8
Pages: 18312-27
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Publication
24324819 | J:209739
First Author: d'Errico P
Year: 2013
Journal: PLoS One
Title: Selective vulnerability of spinal and cortical motor neuron subpopulations in delta7 SMA mice.
Volume: 8
Issue: 12
Pages: e82654
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Publication
35913953 | J:327171
First Author: Carlini MJ
Year: 2022
Journal: PLoS One
Title: Neuromuscular denervation and deafferentation but not motor neuron death are disease features in the Smn2B/- mouse model of SMA.
Volume: 17
Issue: 8
Pages: e0267990
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Publication
25104390 | J:216311
First Author: Naryshkin NA
Year: 2014
Journal: Science
Title: Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy.
Volume: 345
Issue: 6197
Pages: 688-93
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Publication
29440993 | J:312058
 
First Author: Boido M
Year: 2018
Journal: Front Cell Neurosci
Title: Increasing Agrin Function Antagonizes Muscle Atrophy and Motor Impairment in Spinal Muscular Atrophy.
Volume: 12
Pages: 17
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Publication
34413305 | J:308940
First Author: Riboldi GM
Year: 2021
Journal: Nat Commun
Title: Sumoylation regulates the assembly and activity of the SMN complex.
Volume: 12
Issue: 1
Pages: 5040
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Publication
19884170 | J:155336
First Author: Murray LM
Year: 2010
Journal: Hum Mol Genet
Title: Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy.
Volume: 19
Issue: 3
Pages: 420-33
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Publication
26911699 | J:231598
First Author: Zhou C
Year: 2016
Journal: J Neurosci
Title: Defects in Motoneuron-Astrocyte Interactions in Spinal Muscular Atrophy.
Volume: 36
Issue: 8
Pages: 2543-53
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Publication
36757138 | J:341018
First Author: Ojala KS
Year: 2023
Journal: Hum Mol Genet
Title: Potentiation of neuromuscular transmission by a small molecule calcium channel gating modifier improves motor function in a severe spinal muscular atrophy mouse model.
Volume: 32
Issue: 11
Pages: 1901-1911
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Publication
25055867 | J:215597
First Author: Kye MJ
Year: 2014
Journal: Hum Mol Genet
Title: SMN regulates axonal local translation via miR-183/mTOR pathway.
Volume: 23
Issue: 23
Pages: 6318-31
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Publication
21118896 | J:168716
First Author: Dominguez E
Year: 2011
Journal: Hum Mol Genet
Title: Intravenous scAAV9 delivery of a codon-optimized SMN1 sequence rescues SMA mice.
Volume: 20
Issue: 4
Pages: 681-93
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Publication
20089893 | J:157700
First Author: Ruiz R
Year: 2010
Journal: J Neurosci
Title: Altered intracellular Ca2+ homeostasis in nerve terminals of severe spinal muscular atrophy mice.
Volume: 30
Issue: 3
Pages: 849-57
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Publication
27907033 | J:251397
First Author: Arnold WD
Year: 2016
Journal: PLoS One
Title: Normalization of Patient-Identified Plasma Biomarkers in SMNΔ7 Mice following Postnatal SMN Restoration.
Volume: 11
Issue: 12
Pages: e0167077
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Publication
26030275 | J:237725
First Author: Valsecchi V
Year: 2015
Journal: PLoS One
Title: Expression of Muscle-Specific MiRNA 206 in the Progression of Disease in a Murine SMA Model.
Volume: 10
Issue: 6
Pages: e0128560
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Publication
28823932 | J:268309
 
First Author: Tapia O
Year: 2017
Journal: Neurobiol Dis
Title: Cellular bases of the RNA metabolism dysfunction in motor neurons of a murine model of spinal muscular atrophy: Role of Cajal bodies and the nucleolus.
Volume: 108
Pages: 83-99
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Publication
30792629 | J:277613
 
First Author: Sun J
Year: 2019
Journal: Front Cell Neurosci
Title: The Alteration of Intrinsic Excitability and Synaptic Transmission in Lumbar Spinal Motor Neurons and Interneurons of Severe Spinal Muscular Atrophy Mice.
Volume: 13
Pages: 15
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Publication
23656793 | J:199128
First Author: Farooq F
Year: 2013
Journal: Hum Mol Genet
Title: Celecoxib increases SMN and survival in a severe spinal muscular atrophy mouse model via p38 pathway activation.
Volume: 22
Issue: 17
Pages: 3415-24
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Publication
24332368 | J:204134
First Author: Tisdale S
Year: 2013
Journal: Cell Rep
Title: SMN is essential for the biogenesis of U7 small nuclear ribonucleoprotein and 3'-end formation of histone mRNAs.
Volume: 5
Issue: 5
Pages: 1187-95
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Publication
31127156 | J:279895
First Author: Rimer M
Year: 2019
Journal: Sci Rep
Title: Nerve sprouting capacity in a pharmacologically induced mouse model of spinal muscular atrophy.
Volume: 9
Issue: 1
Pages: 7799
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Publication
19074460 | J:145746
First Author: Rose FF Jr
Year: 2009
Journal: Hum Mol Genet
Title: Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy.
Volume: 18
Issue: 6
Pages: 997-1005
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Publication
22763238 | J:187404
First Author: Bebee TW
Year: 2012
Journal: Hum Mol Genet
Title: Hypoxia is a modifier of SMN2 splicing and disease severity in a severe SMA mouse model.
Volume: 21
Issue: 19
Pages: 4301-13
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Publication
33144430 | J:315666
First Author: Ando S
Year: 2020
Journal: In Vivo
Title: SMN Protein Contributes to Skeletal Muscle Cell Maturation Via Caspase-3 and Akt Activation.
Volume: 34
Issue: 6
Pages: 3247-3254
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Publication
22186025 | J:181560
First Author: Porensky PN
Year: 2012
Journal: Hum Mol Genet
Title: A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse.
Volume: 21
Issue: 7
Pages: 1625-38
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Publication
24191055 | J:202974
First Author: Zhang Z
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Dysregulation of synaptogenesis genes antecedes motor neuron pathology in spinal muscular atrophy.
Volume: 110
Issue: 48
Pages: 19348-53
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Publication
18065780 | J:132467
First Author: Murray LM
Year: 2008
Journal: Hum Mol Genet
Title: Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy.
Volume: 17
Issue: 7
Pages: 949-62
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Publication
36604149 | J:334407
 
First Author: Ikenaka A
Year: 2023
Journal: Life Sci Alliance
Title: SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis.
Volume: 6
Issue: 3
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Publication
33234679 | J:305014
 
First Author: Rietz A
Year: 2021
Journal: Life Sci Alliance
Title: Short-duration splice promoting compound enables a tunable mouse model of spinal muscular atrophy.
Volume: 4
Issue: 1
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Publication
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