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Search results 1 to 100 out of 132 for Mlxipl

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Type Details Score
Publication
11230181 | J:67982
First Author: Cairo S
Year: 2001
Journal: Hum Mol Genet
Title: WBSCR14, a gene mapping to the Williams--Beuren syndrome deleted region, is a new member of the Mlx transcription factor network.
Volume: 10
Issue: 6
Pages: 617-27
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Publication
29263303 | J:262502
 
First Author: Kim M
Year: 2017
Journal: JCI Insight
Title: Intestinal, but not hepatic, ChREBP is required for fructose tolerance.
Volume: 2
Issue: 24
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Publication
35908073 | J:327368
First Author: Katz LS
Year: 2022
Journal: Nat Commun
Title: Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure.
Volume: 13
Issue: 1
Pages: 4423
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Publication
29069585 | J:255248
First Author: Vijayakumar A
Year: 2017
Journal: Cell Rep
Title: Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport.
Volume: 21
Issue: 4
Pages: 1021-1035
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Publication
29107286 | J:263597
First Author: Jois T
Year: 2017
Journal: Mol Metab
Title: Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice.
Volume: 6
Issue: 11
Pages: 1381-1394
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Publication
15118080 | J:89865
First Author: Iizuka K
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis.
Volume: 101
Issue: 19
Pages: 7281-6
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Publication
18042547 | J:130720
First Author: Burgess SC
Year: 2008
Journal: J Biol Chem
Title: Carbohydrate-response element-binding protein deletion alters substrate utilization producing an energy-deficient liver.
Volume: 283
Issue: 3
Pages: 1670-8
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Publication
28628040 | J:244608
First Author: Zhang D
Year: 2017
Journal: J Clin Invest
Title: Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity.
Volume: 127
Issue: 7
Pages: 2855-2867
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Publication
29669261 | J:273754
 
First Author: Oh AR
Year: 2018
Journal: Metabolism
Title: ChREBP deficiency leads to diarrhea-predominant irritable bowel syndrome.
Volume: 85
Pages: 286-297
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Publication
29534502 | J:271899
 
First Author: Kato T
Year: 2018
Journal: Nutrients
Title: ChREBP-Knockout Mice Show Sucrose Intolerance and Fructose Malabsorption.
Volume: 10
Issue: 3
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Publication
34021470 | J:340120
First Author: Sakiyama H
Year: 2021
Journal: Mol Cell Biochem
Title: A lack of ChREBP inhibits mitochondrial cristae formation in brown adipose tissue.
Volume: 476
Issue: 10
Pages: 3577-3590
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Publication
25931000 | J:228474
First Author: Wu W
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Fat and carbohydrate in western diet contribute differently to hepatic lipid accumulation.
Volume: 461
Issue: 4
Pages: 681-6
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Publication
22586588 | J:208459
First Author: Metukuri MR
Year: 2012
Journal: Diabetes
Title: ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.
Volume: 61
Issue: 8
Pages: 2004-15
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Publication
27669460 | J:239554
First Author: Kim MS
Year: 2016
Journal: J Clin Invest
Title: ChREBP regulates fructose-induced glucose production independently of insulin signaling.
Volume: 126
Issue: 11
Pages: 4372-4386
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Publication
31813922 | J:301156
First Author: Suzuki S
Year: 2020
Journal: Endocr J
Title: Expression and pathophysiological significance of carbohydrate response element binding protein (ChREBP) in the renal tubules of diabetic kidney.
Volume: 67
Issue: 3
Pages: 335-345
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Publication
15163635 | J:133014
First Author: Merla G
Year: 2004
Journal: Hum Mol Genet
Title: The subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3.
Volume: 13
Issue: 14
Pages: 1505-14
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Publication
18591247 | J:161104
First Author: Davies MN
Year: 2008
Journal: J Biol Chem
Title: Glucose activates ChREBP by increasing its rate of nuclear entry and relieving repression of its transcriptional activity.
Volume: 283
Issue: 35
Pages: 24029-38
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Publication
16184193 | J:101751
First Author: Dentin R
Year: 2005
Journal: J Clin Invest
Title: Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation.
Volume: 115
Issue: 10
Pages: 2843-54
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Publication
16873678 | J:116482
First Author: Dentin R
Year: 2006
Journal: Diabetes
Title: Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.
Volume: 55
Issue: 8
Pages: 2159-70
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Publication
19995986 | J:155812
First Author: Tong X
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation.
Volume: 106
Issue: 51
Pages: 21660-5
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Publication
21215280 | J:170664
First Author: Hanke N
Year: 2011
Journal: Biochim Biophys Acta
Title: Gene regulation mediating fiber-type transformation in skeletal muscle cells is partly glucose- and ChREBP-dependent.
Volume: 1813
Issue: 3
Pages: 377-89
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Publication
22382520 | J:184995
First Author: Poungvarin N
Year: 2012
Journal: Diabetologia
Title: Carbohydrate response element-binding protein (ChREBP) plays a pivotal role in beta cell glucotoxicity.
Volume: 55
Issue: 6
Pages: 1783-96
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Publication
22546860 | J:188296
First Author: Benhamed F
Year: 2012
Journal: J Clin Invest
Title: The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans.
Volume: 122
Issue: 6
Pages: 2176-94
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Publication
26384380 | J:246403
First Author: Zhang P
Year: 2015
Journal: Diabetes
Title: Induction of the ChREBPβ Isoform Is Essential for Glucose-Stimulated β-Cell Proliferation.
Volume: 64
Issue: 12
Pages: 4158-70
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Publication
27992582 | J:251459
First Author: Jois T
Year: 2016
Journal: PLoS One
Title: Dietary Macronutrient Composition Directs ChREBP Isoform Expression and Glucose Metabolism in Mice.
Volume: 11
Issue: 12
Pages: e0168797
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Publication
30405056 | J:295675
 
First Author: Iizuka K
Year: 2018
Journal: Nutrients
Title: ChREBP Reciprocally Regulates Liver and Plasma Triacylglycerol Levels in Different Manners.
Volume: 10
Issue: 11
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Publication
29965794 | J:316522
First Author: Ribback S
Year: 2018
Journal: Cell Cycle
Title: Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinoma.
Volume: 17
Issue: 12
Pages: 1496-1512
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Publication
36413406 | J:339849
 
First Author: Sargsyan A
Year: 2023
Journal: JCI Insight
Title: HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis.
Volume: 8
Issue: 1
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Publication
25303528 | J:217547
First Author: Yore MM
Year: 2014
Journal: Cell
Title: Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.
Volume: 159
Issue: 2
Pages: 318-32
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Publication
38167725 | J:344286
First Author: Worthmann A
Year: 2024
Journal: Nat Commun
Title: Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use.
Volume: 15
Issue: 1
Pages: 45
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Publication
29282201 | J:258313
First Author: Richards P
Year: 2018
Journal: Diabetes
Title: MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells.
Volume: 67
Issue: 3
Pages: 461-472
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Publication
14742444 | J:89514
First Author: Stoeckman AK
Year: 2004
Journal: J Biol Chem
Title: Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes.
Volume: 279
Issue: 15
Pages: 15662-9
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15496471 | J:93447
First Author: Ishii S
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription.
Volume: 101
Issue: 44
Pages: 15597-602
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Publication
22338092 | J:196242
First Author: Noordeen NA
Year: 2012
Journal: Diabetes
Title: Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells.
Volume: 61
Issue: 3
Pages: 574-85
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Publication
22466288 | J:183854
First Author: Herman MA
Year: 2012
Journal: Nature
Title: A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism.
Volume: 484
Issue: 7394
Pages: 333-8
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Publication
33440156 | J:304287
First Author: Schlein C
Year: 2021
Journal: Cell Rep
Title: Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution.
Volume: 34
Issue: 2
Pages: 108624
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Publication
16705063 | J:111374
First Author: Iizuka K
Year: 2006
Journal: Am J Physiol Endocrinol Metab
Title: Deficiency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (ob/ob) mice.
Volume: 291
Issue: 2
Pages: E358-64
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Publication
33023907 | J:299411
First Author: Heidenreich S
Year: 2020
Journal: J Biol Chem
Title: The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation.
Volume: 295
Issue: 50
Pages: 17158-17168
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Publication
28606928 | J:247199
First Author: Chau GC
Year: 2017
Journal: J Cell Biol
Title: mTOR controls ChREBP transcriptional activity and pancreatic β cell survival under diabetic stress.
Volume: 216
Issue: 7
Pages: 2091-2105
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Publication
21103071 | J:179193
First Author: Wang RH
Year: 2010
Journal: Int J Biol Sci
Title: Liver steatosis and increased ChREBP expression in mice carrying a liver specific SIRT1 null mutation under a normal feeding condition.
Volume: 6
Issue: 7
Pages: 682-90
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Publication
29335275 | J:262508
First Author: Linden AG
Year: 2018
Journal: J Lipid Res
Title: Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice.
Volume: 59
Issue: 3
Pages: 475-487
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Publication
20854262 | J:167019
First Author: Grefhorst A
Year: 2010
Journal: Biochem J
Title: Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1.
Volume: 432
Issue: 2
Pages: 249-54
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Publication
29764859 | J:264034
First Author: Kumar A
Year: 2018
Journal: Diabetes
Title: Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation.
Volume: 67
Issue: 8
Pages: 1561-1575
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Publication
37611830 | J:340799
First Author: Li L
Year: 2023
Journal: J Biol Chem
Title: The transcription factor ChREBP links mitochondrial lipidomes to mitochondrial morphology and progression of diabetic kidney disease.
Volume: 299
Issue: 9
Pages: 105185
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Publication
31974143 | J:286982
First Author: Shi JH
Year: 2020
Journal: Diabetes
Title: Liver ChREBP Protects Against Fructose-Induced Glycogenic Hepatotoxicity by Regulating L-Type Pyruvate Kinase.
Volume: 69
Issue: 4
Pages: 591-602
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Publication
29518948 | J:276258
 
First Author: Niwa H
Year: 2018
Journal: Nutrients
Title: ChREBP Rather Than SHP Regulates Hepatic VLDL Secretion.
Volume: 10
Issue: 3
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Publication
19324998 | J:151800
First Author: Hashimoto K
Year: 2009
Journal: Endocrinology
Title: Carbohydrate response element binding protein gene expression is positively regulated by thyroid hormone.
Volume: 150
Issue: 7
Pages: 3417-24
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Publication
19833882 | J:164167
First Author: Noordeen NA
Year: 2010
Journal: Diabetes
Title: Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells.
Volume: 59
Issue: 1
Pages: 153-60
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Publication
20934404 | J:166930
First Author: da Silva Xavier G
Year: 2010
Journal: Biochem Biophys Res Commun
Title: ChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cells.
Volume: 402
Issue: 2
Pages: 252-7
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Publication
29020627 | J:262506
First Author: Iroz A
Year: 2017
Journal: Cell Rep
Title: A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response.
Volume: 21
Issue: 2
Pages: 403-416
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Publication
32416328 | J:299384
 
First Author: Kim KM
Year: 2020
Journal: Int J Biochem Cell Biol
Title: Carbohydrate responsive element binding protein (ChREBP) negatively regulates osteoblast differentiation via protein phosphatase 2A Cα dependent manner.
Volume: 124
Pages: 105766
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Publication
33137488 | J:342693
 
First Author: Rajas F
Year: 2021
Journal: Mol Metab
Title: The absence of hepatic glucose-6 phosphatase/ChREBP couple is incompatible with survival in mice.
Volume: 43
Pages: 101108
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Publication
26411684 | J:315388
First Author: Sarrazy V
Year: 2015
Journal: Cell Rep
Title: Maintenance of Macrophage Redox Status by ChREBP Limits Inflammation and Apoptosis and Protects against Advanced Atherosclerotic Lesion Formation.
Volume: 13
Issue: 1
Pages: 132-144
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Publication
10780788 | J:61965
First Author: de Luis O
Year: 2000
Journal: Eur J Hum Genet
Title: WBSCR14, a putative transcription factor gene deleted in Williams-Beuren syndrome: complete characterisation of the human gene and the mouse ortholog.
Volume: 8
Issue: 3
Pages: 215-22
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Publication
26724858 | J:232863
First Author: von Holstein-Rathlou S
Year: 2016
Journal: Cell Metab
Title: FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver.
Volume: 23
Issue: 2
Pages: 335-43
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Publication
32246987 | J:293502
 
First Author: Tong X
Year: 2020
Journal: Metabolism
Title: DDB1 E3 ligase controls dietary fructose-induced ChREBPα stabilization and liver steatosis via CRY1.
Volume: 107
Pages: 154222
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Publication
34669700 | J:324060
First Author: Carroll PA
Year: 2021
Journal: PLoS Biol
Title: The glucose-sensing transcription factor MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis.
Volume: 19
Issue: 10
Pages: e3001085
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Publication
27098609 | J:236883
 
First Author: Tang Y
Year: 2016
Journal: Nat Commun
Title: Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
Volume: 7
Pages: 11365
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Publication
30087120 | J:271043
First Author: Wang H
Year: 2018
Journal: J Biol Chem
Title: Myc and ChREBP transcription factors cooperatively regulate normal and neoplastic hepatocyte proliferation in mice.
Volume: 293
Issue: 38
Pages: 14740-14757
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Publication
21471514 | J:171811
First Author: Guinez C
Year: 2011
Journal: Diabetes
Title: O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver.
Volume: 60
Issue: 5
Pages: 1399-413
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11698644 | J:135493
First Author: Kawaguchi T
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein.
Volume: 98
Issue: 24
Pages: 13710-5
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18765640 | J:141176
First Author: Perilhou A
Year: 2008
Journal: Mol Cell Biol
Title: The transcription factor COUP-TFII is negatively regulated by insulin and glucose via Foxo1- and ChREBP-controlled pathways.
Volume: 28
Issue: 21
Pages: 6568-79
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Publication
27524233 | J:238955
First Author: Bae JS
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Hepatic Elovl6 gene expression is regulated by the synergistic action of ChREBP and SREBP-1c.
Volume: 478
Issue: 3
Pages: 1060-6
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Publication
36054206 | J:327977
First Author: Thevkar-Nagesh P
Year: 2022
Journal: PLoS One
Title: Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation.
Volume: 17
Issue: 9
Pages: e0272986
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Publication
25724563 | J:221134
First Author: Bindesbøll C
Year: 2015
Journal: J Lipid Res
Title: Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity.
Volume: 56
Issue: 4
Pages: 771-85
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Publication
18292813 | J:135655
First Author: Denechaud PD
Year: 2008
Journal: J Clin Invest
Title: ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver.
Volume: 118
Issue: 3
Pages: 956-64
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Publication
29153407 | J:256875
First Author: Sanchez-Gurmaches J
Year: 2018
Journal: Cell Metab
Title: Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis.
Volume: 27
Issue: 1
Pages: 195-209.e6
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Publication
14985368 | J:124295
First Author: Dentin R
Year: 2004
Journal: J Biol Chem
Title: Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression.
Volume: 279
Issue: 19
Pages: 20314-26
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Publication
21084751 | J:171868
First Author: Bricambert J
Year: 2010
Journal: J Clin Invest
Title: Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice.
Volume: 120
Issue: 12
Pages: 4316-31
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Publication
21357625 | J:172091
First Author: Pashkov V
Year: 2011
Journal: J Biol Chem
Title: Regulator of G protein signaling (RGS16) inhibits hepatic fatty acid oxidation in a carbohydrate response element-binding protein (ChREBP)-dependent manner.
Volume: 286
Issue: 17
Pages: 15116-25
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Publication
34425214 | J:312956
First Author: Zhu C
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: SIRT6 controls hepatic lipogenesis by suppressing LXR, ChREBP, and SREBP1.
Volume: 1867
Issue: 12
Pages: 166249
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Publication
17107947 | J:154828
First Author: Cha JY
Year: 2007
Journal: J Biol Chem
Title: The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR.
Volume: 282
Issue: 1
Pages: 743-51
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35259493 | J:324041
First Author: Wang H
Year: 2022
Journal: Cell Mol Gastroenterol Hepatol
Title: Coordinated Cross-Talk Between the Myc and Mlx Networks in Liver Regeneration and Neoplasia.
Volume: 13
Issue: 6
Pages: 1785-1804
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Publication
18606808 | J:142024
First Author: Sakiyama H
Year: 2008
Journal: J Biol Chem
Title: Regulation of nuclear import/export of carbohydrate response element-binding protein (ChREBP): interaction of an alpha-helix of ChREBP with the 14-3-3 proteins and regulation by phosphorylation.
Volume: 283
Issue: 36
Pages: 24899-908
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Publication
20534694 | J:182863
First Author: Gao N
Year: 2010
Journal: Mol Endocrinol
Title: Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell.
Volume: 24
Issue: 8
Pages: 1594-604
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24717294 | J:238264
First Author: Clar J
Year: 2014
Journal: Kidney Int
Title: Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy.
Volume: 86
Issue: 4
Pages: 747-56
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Publication
26091038 | J:223511
First Author: Wei J
Year: 2015
Journal: Cell
Title: Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation.
Volume: 161
Issue: 7
Pages: 1576-1591
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25249504 | J:218426
First Author: Kahraman S
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring.
Volume: 307
Issue: 10
Pages: E906-18
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22055502 | J:179687
First Author: Banks AS
Year: 2011
Journal: Cell Metab
Title: Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice.
Volume: 14
Issue: 5
Pages: 587-97
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30661759 | J:338071
First Author: Sharon N
Year: 2019
Journal: Cell
Title: A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets.
Volume: 176
Issue: 4
Pages: 790-804.e13
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27974211 | J:241708
First Author: Luo X
Year: 2016
Journal: Cell Rep
Title: Dual Shp2 and Pten Deficiencies Promote Non-alcoholic Steatohepatitis and Genesis of Liver Tumor-Initiating Cells.
Volume: 17
Issue: 11
Pages: 2979-2993
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26508642 | J:227474
First Author: Fonseca TL
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.
Volume: 112
Issue: 45
Pages: 14018-23
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22872236 | J:208504
First Author: Qiao L
Year: 2012
Journal: Diabetes
Title: Adiponectin enhances mouse fetal fat deposition.
Volume: 61
Issue: 12
Pages: 3199-207
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11779826 | J:73830
First Author: DeSilva U
Year: 2002
Journal: Genome Res
Title: Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome.
Volume: 12
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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