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Search results 2501 to 2600 out of 2904 for Pdx1

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Type Details Score
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre)1Herr/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-Bgeo/GFP)21Lbe/? Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pdx1/Pdx1<+>
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mafa/Mafa Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mafa/Mafa Mafb/Mafb Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmpr1a/Bmpr1a Tg(Pdx1-cre)1Herr/?
Background: B6.Cg-Bmpr1a Tg(Pdx1-cre)1Herr
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stk3/Stk3<+> Stk4/Stk4 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stk3/Stk3 Stk4/Stk4 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sirt1/Sirt1 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kdm6a/Kdm6a Tg(Pdx1-cre)6Tuv/?
Background: involves: C57BL/6J * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-flpo)#Koli/?
Background: involves: 129S4/SvJaeSor * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Onecut1/Onecut1<+> Pdx1/Pdx1<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lats1/Lats1 Lats2/Lats2 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S6/SvEvTac * C57BL/6Brd * CBA * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Pdx1-cre)6Tuv/? Tle3/Tle3 Tle4/Tle4
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kdm6b/Kdm6b Neurog3/Neurog3<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
18421434 | J:137920
First Author: Mehrabian M
Year: 2008
Journal: Diabetologia
Title: Identification of ALOX5 as a gene regulating adiposity and pancreatic function.
Volume: 51
Issue: 6
Pages: 978-88
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Publication
12493745 | J:82924
First Author: Terauchi Y
Year: 2003
Journal: J Biol Chem
Title: Impact of genetic background and ablation of insulin receptor substrate (IRS)-3 on IRS-2 knock-out mice.
Volume: 278
Issue: 16
Pages: 14284-90
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Publication
23251699 | J:195661
First Author: van der Meulen T
Year: 2012
Journal: PLoS One
Title: Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cells.
Volume: 7
Issue: 12
Pages: e52181
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Publication
28377501 | J:243672
First Author: Mitchell RK
Year: 2017
Journal: J Biol Chem
Title: The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice.
Volume: 292
Issue: 21
Pages: 8892-8906
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Publication
28642969 | J:252014
First Author: Ida S
Year: 2017
Journal: Diabetologia
Title: Diverse metabolic effects of O-GlcNAcylation in the pancreas but limited effects in insulin-sensitive organs in mice.
Volume: 60
Issue: 9
Pages: 1761-1769
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Publication
23531612 | J:198216
First Author: Crivello M
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Postnatal development of the endocrine pancreas in mice lacking functional GABAB receptors.
Volume: 304
Issue: 10
Pages: E1064-76
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Publication
24989997 | J:218130
First Author: Chen YC
Year: 2014
Journal: Diabetologia
Title: Mig6 haploinsufficiency protects mice against streptozotocin-induced diabetes.
Volume: 57
Issue: 10
Pages: 2066-75
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Publication
22374815 | J:188469
First Author: Johnson CL
Year: 2012
Journal: J Pathol
Title: Activation of protein kinase Cδ leads to increased pancreatic acinar cell dedifferentiation in the absence of MIST1.
Volume: 228
Issue: 3
Pages: 351-65
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Publication
26546129 | J:230840
First Author: Jurczyk A
Year: 2016
Journal: FASEB J
Title: Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic β-cell function via glycogen synthase kinase-3β.
Volume: 30
Issue: 2
Pages: 983-93
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Publication
22230751 | J:182707
First Author: Miki R
Year: 2012
Journal: Mech Dev
Title: Fate maps of ventral and dorsal pancreatic progenitor cells in early somite stage mouse embryos.
Volume: 128
Issue: 11-12
Pages: 597-609
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Publication
1825611 | -
First Author: Russell GC
Year: 1991
Journal: Biochim Biophys Acta
Title: Sequence similarities within the family of dihydrolipoamide acyltransferases and discovery of a previously unidentified fungal enzyme.
Volume: 1076
Issue: 2
Pages: 225-32
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Publication
20865670 | -
First Author: Kang HS
Year: 2010
Journal: Histol Histopathol
Title: Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease.
Volume: 25
Issue: 11
Pages: 1481-96
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Publication
21996748 | J:186130
First Author: Whipple CA
Year: 2012
Journal: Oncogene
Title: A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis.
Volume: 31
Issue: 20
Pages: 2535-44
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Publication
22565310 | J:188293
First Author: Hamidi T
Year: 2012
Journal: J Clin Invest
Title: Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis.
Volume: 122
Issue: 6
Pages: 2092-103
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Publication
24949970 | J:214528
First Author: Soleimanpour SA
Year: 2014
Journal: Cell
Title: The diabetes susceptibility gene Clec16a regulates mitophagy.
Volume: 157
Issue: 7
Pages: 1577-90
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Publication
21051638 | J:218666
First Author: Kraman M
Year: 2010
Journal: Science
Title: Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha.
Volume: 330
Issue: 6005
Pages: 827-30
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Publication
20627934 | J:169626
First Author: Artner I
Year: 2010
Journal: Diabetes
Title: MafA and MafB regulate genes critical to beta-cells in a unique temporal manner.
Volume: 59
Issue: 10
Pages: 2530-9
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Publication
30366930 | J:271300
First Author: Biffi G
Year: 2019
Journal: Cancer Discov
Title: IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma.
Volume: 9
Issue: 2
Pages: 282-301
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Publication
17114586 | J:116111
First Author: Pasca di Magliano M
Year: 2006
Journal: Genes Dev
Title: Hedgehog/Ras interactions regulate early stages of pancreatic cancer.
Volume: 20
Issue: 22
Pages: 3161-73
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Publication
31848151 | J:285346
First Author: Kim H
Year: 2020
Journal: Diabetes
Title: PRMT1 Is Required for the Maintenance of Mature β-Cell Identity.
Volume: 69
Issue: 3
Pages: 355-368
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Publication
31578522 | J:283349
First Author: Aykut B
Year: 2019
Journal: Nature
Title: The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL.
Volume: 574
Issue: 7777
Pages: 264-267
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Publication
31877165 | J:283370
First Author: Park D
Year: 2019
Journal: PLoS One
Title: Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains.
Volume: 14
Issue: 12
Pages: e0226714
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Publication
28294115 | J:244261
 
First Author: Gundry C
Year: 2017
Journal: Nat Commun
Title: Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion.
Volume: 8
Pages: 14646
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Publication
25452273 | J:217379
First Author: Baer R
Year: 2014
Journal: Genes Dev
Title: Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α.
Volume: 28
Issue: 23
Pages: 2621-35
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Publication
29914854 | J:315908
 
First Author: Burke SJ
Year: 2018
Journal: Mol Metab
Title: Pancreatic deletion of the interleukin-1 receptor disrupts whole body glucose homeostasis and promotes islet β-cell de-differentiation.
Volume: 14
Pages: 95-107
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Publication
35316682 | J:322171
 
First Author: Yang J
Year: 2022
Journal: EBioMedicine
Title: Dynamic profiling of immune microenvironment during pancreatic cancer development suggests early intervention and combination strategy of immunotherapy.
Volume: 78
Pages: 103958
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Publication
24788257 | J:216102
First Author: Morris JP 4th
Year: 2014
Journal: PLoS One
Title: Dicer regulates differentiation and viability during mouse pancreatic cancer initiation.
Volume: 9
Issue: 5
Pages: e95486
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Publication
19246386 | J:146777
First Author: Tian H
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis.
Volume: 106
Issue: 11
Pages: 4254-9
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Publication
21474066 | J:310528
First Author: Kennedy AL
Year: 2011
Journal: Mol Cell
Title: Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis.
Volume: 42
Issue: 1
Pages: 36-49
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Publication
24305049 | J:207920
First Author: Rosenfeldt MT
Year: 2013
Journal: Nature
Title: p53 status determines the role of autophagy in pancreatic tumour development.
Volume: 504
Issue: 7479
Pages: 296-300
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Publication
33603164 | J:303964
First Author: Solan JL
Year: 2021
Journal: Oncogene
Title: Cx43 phosphorylation sites regulate pancreatic cancer metastasis.
Volume: 40
Issue: 10
Pages: 1909-1920
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Publication
27150016 | J:234486
First Author: Amit M
Year: 2016
Journal: Nat Rev Cancer
Title: Mechanisms of cancer dissemination along nerves.
Volume: 16
Issue: 6
Pages: 399-408
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Publication
33323382 | J:303990
First Author: Kon N
Year: 2021
Journal: Cancer Res
Title: Robust p53 Stabilization Is Dispensable for Its Activation and Tumor Suppressor Function.
Volume: 81
Issue: 4
Pages: 935-944
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Publication
29533787 | J:258620
First Author: Andricovich J
Year: 2018
Journal: Cancer Cell
Title: Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors.
Volume: 33
Issue: 3
Pages: 512-526.e8
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Publication
28500323 | J:282268
First Author: Hock AK
Year: 2017
Journal: Sci Rep
Title: Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo.
Volume: 7
Issue: 1
Pages: 1837
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Publication
22945649 | J:199980
First Author: Norris AM
Year: 2013
Journal: Oncogene
Title: AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia.
Volume: 32
Issue: 33
Pages: 3867-76
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Publication
25878147 | J:220300
First Author: Massó-Vallés D
Year: 2015
Journal: Cancer Res
Title: Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma.
Volume: 75
Issue: 8
Pages: 1675-81
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Publication
25843002 | J:220307
First Author: von Karstedt S
Year: 2015
Journal: Cancer Cell
Title: Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis.
Volume: 27
Issue: 4
Pages: 561-73
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Publication
21266354 | J:169401
First Author: Timpson P
Year: 2011
Journal: Cancer Res
Title: Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53.
Volume: 71
Issue: 3
Pages: 747-57
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Publication
26438692 | J:226536
First Author: Gopinathan A
Year: 2015
Journal: Dis Model Mech
Title: GEMMs as preclinical models for testing pancreatic cancer therapies.
Volume: 8
Issue: 10
Pages: 1185-200
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Publication
28581520 | J:247824
First Author: Weng CC
Year: 2017
Journal: Oncogene
Title: KLF10 loss in the pancreas provokes activation of SDF-1 and induces distant metastases of pancreatic ductal adenocarcinoma in the KrasG12D p53flox/flox model.
Volume: 36
Issue: 39
Pages: 5532-5543
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Publication
29529089 | J:258751
First Author: Kim HY
Year: 2018
Journal: PLoS One
Title: RAGE-specific single chain Fv for PET imaging of pancreatic cancer.
Volume: 13
Issue: 3
Pages: e0192821
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Publication
34433637 | J:318716
 
First Author: Belmontes B
Year: 2021
Journal: Sci Transl Med
Title: Immunotherapy combinations overcome resistance to bispecific T cell engager treatment in T cell-cold solid tumors.
Volume: 13
Issue: 608
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Publication
32554750 | J:296297
First Author: Zhao Y
Year: 2020
Journal: Cancer Res
Title: Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A.
Volume: 80
Issue: 16
Pages: 3359-3371
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Publication
30827862 | J:275674
First Author: Halbrook CJ
Year: 2019
Journal: Cell Metab
Title: Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer.
Volume: 29
Issue: 6
Pages: 1390-1399.e6
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Publication
23852374 | J:228608
First Author: Evangelou K
Year: 2013
Journal: Cell Death Differ
Title: The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis.
Volume: 20
Issue: 11
Pages: 1485-97
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Publication
17114584 | J:116130
First Author: Bardeesy N
Year: 2006
Journal: Genes Dev
Title: Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
Volume: 20
Issue: 22
Pages: 3130-46
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Publication
31183403 | J:288756
First Author: Hari P
Year: 2019
Journal: Sci Adv
Title: The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype.
Volume: 5
Issue: 6
Pages: eaaw0254
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Publication
32648540 | J:293907
   
First Author: Lau AN
Year: 2020
Journal: Elife
Title: Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma.
Volume: 9
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Publication
24362629 | J:208277
First Author: Mohseni M
Year: 2014
Journal: Nat Cell Biol
Title: A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway.
Volume: 16
Issue: 1
Pages: 108-17
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Publication
28808255 | J:250841
First Author: Zaytouni T
Year: 2017
Journal: Nat Commun
Title: Critical role for arginase 2 in obesity-associated pancreatic cancer.
Volume: 8
Issue: 1
Pages: 242
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Publication
36256464 | J:332123
 
First Author: Dixit A
Year: 2022
Journal: JCI Insight
Title: Targeting TNF-α-producing macrophages activates antitumor immunity in pancreatic cancer via IL-33 signaling.
Volume: 7
Issue: 22
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Publication
26452271 | J:243686
First Author: Weyandt JD
Year: 2015
Journal: PLoS One
Title: Wild-Type Hras Suppresses the Earliest Stages of Tumorigenesis in a Genetically Engineered Mouse Model of Pancreatic Cancer.
Volume: 10
Issue: 10
Pages: e0140253
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Publication
22509024 | J:183916
First Author: Kang R
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia.
Volume: 109
Issue: 18
Pages: 7031-6
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Publication
30061636 | J:267421
First Author: Ferro R
Year: 2018
Journal: Oncogene
Title: GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine.
Volume: 37
Issue: 49
Pages: 6368-6382
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Publication
24898060 | J:214456
First Author: Alderton GK
Year: 2014
Journal: Nat Rev Cancer
Title: Microenvironment: An exercise in restraint.
Volume: 14
Issue: 7
Pages: 449
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Publication
27941872 | J:243050
First Author: Dumartin L
Year: 2017
Journal: Oncogene
Title: ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation.
Volume: 36
Issue: 22
Pages: 3094-3103
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Publication
27216178 | J:232779
First Author: Schultz MJ
Year: 2016
Journal: Cancer Res
Title: The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype.
Volume: 76
Issue: 13
Pages: 3978-88
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Publication
27197190 | J:232784
First Author: Yang S
Year: 2016
Journal: Cancer Res
Title: A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2.
Volume: 76
Issue: 13
Pages: 3838-50
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Publication
26525103 | J:226758
First Author: Stromnes IM
Year: 2015
Journal: Cancer Cell
Title: T Cells Engineered against a Native Antigen Can Surmount Immunologic and Physical Barriers to Treat Pancreatic Ductal Adenocarcinoma.
Volume: 28
Issue: 5
Pages: 638-652
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Publication
26279302 | J:309335
First Author: Zhang S
Year: 2016
Journal: Oncogene
Title: Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer.
Volume: 35
Issue: 19
Pages: 2485-95
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Publication
29596465 | J:261064
First Author: Germino EA
Year: 2018
Journal: PLoS One
Title: Homozygous KSR1 deletion attenuates morbidity but does not prevent tumor development in a mouse model of RAS-driven pancreatic cancer.
Volume: 13
Issue: 3
Pages: e0194998
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Publication
26575024 | J:280480
First Author: Mace TA
Year: 2015
Journal: Oncotarget
Title: Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer.
Volume: 6
Issue: 42
Pages: 44509-22
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Publication
22056382 | J:184026
First Author: Maniati E
Year: 2011
Journal: J Clin Invest
Title: Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice.
Volume: 121
Issue: 12
Pages: 4685-99
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Publication
16585505 | J:108298
First Author: Bardeesy N
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Volume: 103
Issue: 15
Pages: 5947-52
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Publication
26479921 | J:228885
First Author: Alam MS
Year: 2015
Journal: Nat Med
Title: Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression.
Volume: 21
Issue: 11
Pages: 1337-43
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Publication
23873029 | J:212617
First Author: Tan EH
Year: 2014
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