SULT1B1 is a sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyse the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds []. It catalyses the sulfation of p-nitrophenol, 3,3',5-triiodothyronine (T3) as a typical endogenous substrate in rats and humans []. Its structure has been revealed [].
