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Search results 201 to 300 out of 381 for Chl1

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Type Details Score
GXD Expression
Probe: MGI:1380686
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5291720
Age: embryonic day 8.5
Image: E8.5
Note: Expression is present in the ventral neural tube.
Specimen Label: E8.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884397
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4945634
Age: embryonic day 11.5
Image: g01169 E11.5
Note: Expression was region specific and scattered.
Specimen Label: g01169 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884397
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945634
Age: postnatal day 7
Image: g01169 P7
Specimen Label: g01169 P7
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4457143
Assay Type: Immunohistochemistry
Annotation Date: 2010-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4457151
Age: embryonic day 15.5
Specimen Label: 1J
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7616285
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7616374
Age: embryonic day 18.5
Note: Severely hypoplastic, compared with the control.
Specimen Label: 1A 11/11'
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:7616285
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7616374
Age: embryonic day 18.5
Specimen Label: 1A 2/2'
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7616285
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7616374
Age: embryonic day 18.5
Note: Similar as in the wild-type.
Specimen Label: 1A 5/5'
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:7616285
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7616374
Age: embryonic day 18.5
Note: Similar as in the wild-type.
Specimen Label: 1A 8/8'
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7616285
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7616374
Age: postnatal day 1
Specimen Label: 3 control Middle
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:7616285
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7616374
Age: postnatal day 1
Note: Similar as in the control.
Specimen Label: 3 Atg7-cKO Middle
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:7616285
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7616374
Age: postnatal day 1
Note: Similar as in the control.
Specimen Label: 3 Rb1cc1-cKO Middle
Detected: true
Specimen Num: 25
GXD Expression  
Probe: MGI:7616285
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7616374
Age: postnatal day 1
Note: Hypoplastic anterior commissure was seen.
Specimen Label: 3 Ulk1/2-cDKO Middle
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:3574060
Assay Type: RNA in situ
Annotation Date: 2005-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3534328
Pattern: Single cells
Stage: TS28
Assay Id: MGI:3574075
Age: postnatal day 13
Note: Expression is present in a few cells in all branches of the femoral nerve.
Specimen Label: 2E
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3574060
Assay Type: RNA in situ
Annotation Date: 2005-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3574075
Age: postnatal day 7
Note: Expression is less strong in the medial/lateral thalamus than in other parts of the thalamus.
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3574060
Assay Type: RNA in situ
Annotation Date: 2005-04-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3574075
Age: postnatal week 3
Specimen Label: 2C
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884397
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945634
Age: postnatal day 7
Image: g01169 P7
Specimen Label: g01169 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884397
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945634
Age: postnatal day 42
Image: g01169 Adult
Specimen Label: g01169 Adult
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4884397
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:4945634
Age: postnatal day 42
Image: g01169 Adult
Specimen Label: g01169 Adult
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:3574060
Assay Type: RNA in situ
Annotation Date: 2005-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3527628
Stage: TS28
Assay Id: MGI:3574075
Age: postnatal day 7
Specimen Label: 2A
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3574060
Assay Type: RNA in situ
Annotation Date: 2005-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3527628
Pattern: Uniform
Stage: TS28
Assay Id: MGI:3574075
Age: postnatal week 3
Specimen Label: 2C
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884397
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945634
Age: embryonic day 15.5
Image: g01169 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g01169 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884397
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945634
Age: embryonic day 15.5
Image: g01169 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g01169 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884397
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945634
Age: postnatal day 7
Image: g01169 P7
Note: Expression was region specific and scattered.
Specimen Label: g01169 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4884397
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945634
Age: postnatal day 42
Image: g01169 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01169 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6457061
Assay Type: RNA in situ
Annotation Date: 2020-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6480006
Age: embryonic day 14.5
Image: S1D
Specimen Label: S1D
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6457061
Assay Type: RNA in situ
Annotation Date: 2020-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6480006
Age: postnatal day 0
Image: S1E
Specimen Label: S1E
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6457061
Assay Type: RNA in situ
Annotation Date: 2020-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6480006
Age: postnatal day 4
Image: S1F
Specimen Label: S1F
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6457061
Assay Type: RNA in situ
Annotation Date: 2020-12-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Ubiquitous
Stage: TS23
Assay Id: MGI:6480006
Age: embryonic day 15.5
Specimen Label: S1 Table A11
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7423815
Assay Type: RNA in situ
Annotation Date: 2023-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7425399
Age: embryonic day 16.5
Note: Expression is seen in mesenchyme near the olfactory nerve layer and the olfactory mucosal mesenchyme.
Specimen Label: File S3
Detected: true
Specimen Num: 1
Publication
First Author: Bye CR
Year: 2019
Journal: J Neurosci
Title: Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins.
Volume: 39
Issue: 34
Pages: 6656-6667
Publication
First Author: Hortsch M
Year: 2000
Journal: Mol Cell Neurosci
Title: Structural and functional evolution of the L1 family: are four adhesion molecules better than one?
Volume: 15
Issue: 1
Pages: 1-10
Publication
First Author: Dai J
Year: 2012
Journal: Mol Cell Neurosci
Title: EphB regulates L1 phosphorylation during retinocollicular mapping.
Volume: 50
Issue: 2
Pages: 201-10
Publication  
First Author: Van Battum EY
Year: 2014
Journal: Nat Commun
Title: The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections.
Volume: 5
Pages: 4317
Publication
First Author: Ashrafi S
Year: 2014
Journal: Neuron
Title: Neuronal Ig/Caspr recognition promotes the formation of axoaxonic synapses in mouse spinal cord.
Volume: 81
Issue: 1
Pages: 120-9
Publication
First Author: Lee DY
Year: 2012
Journal: Cancer Cell
Title: Innate neural stem cell heterogeneity determines the patterning of glioma formation in children.
Volume: 22
Issue: 1
Pages: 131-8
Publication
First Author: Maejima I
Year: 2023
Journal: Commun Biol
Title: RAB35 is required for murine hippocampal development and functions by regulating neuronal cell distribution.
Volume: 6
Issue: 1
Pages: 440
Publication
First Author: Lutz D
Year: 2017
Journal: Sci Rep
Title: Proteolytic cleavage of transmembrane cell adhesion molecule L1 by extracellular matrix molecule Reelin is important for mouse brain development.
Volume: 7
Issue: 1
Pages: 15268
Publication
First Author: Li S
Year: 2013
Journal: J Neurosci
Title: Endothelial VEGF sculpts cortical cytoarchitecture.
Volume: 33
Issue: 37
Pages: 14809-15
Publication
First Author: Williams SE
Year: 2006
Journal: Neuron
Title: A role for Nr-CAM in the patterning of binocular visual pathways.
Volume: 50
Issue: 4
Pages: 535-47
Publication
First Author: Faux C
Year: 2010
Journal: J Comp Neurol
Title: Differential gene expression in migrating cortical interneurons during mouse forebrain development.
Volume: 518
Issue: 8
Pages: 1232-48
Publication
First Author: Namba T
Year: 2014
Journal: Neuron
Title: Pioneering axons regulate neuronal polarization in the developing cerebral cortex.
Volume: 81
Issue: 4
Pages: 814-29
Publication
First Author: Liu T
Year: 2015
Journal: Mol Neurobiol
Title: A MicroRNA Profile in Fmr1 Knockout Mice Reveals MicroRNA Expression Alterations with Possible Roles in Fragile X Syndrome.
Volume: 51
Issue: 3
Pages: 1053-63
Publication      
First Author: Moreau MX
Year: 2023
Journal: Dev Cell
Title: Repurposing of the multiciliation gene regulatory network in fate specification of Cajal-Retzius neurons.
Publication
First Author: Wang B
Year: 2018
Journal: Autophagy
Title: The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway.
Volume: 14
Issue: 5
Pages: 796-811
Publication    
First Author: Singh S
Year: 2016
Journal: Elife
Title: Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition.
Volume: 5
Publication
First Author: Maheshwari U
Year: 2020
Journal: Cell Rep
Title: Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets.
Volume: 31
Issue: 11
Pages: 107767
Publication
First Author: Tulloch AJ
Year: 2019
Journal: J Comp Neurol
Title: Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse.
Volume: 527
Issue: 18
Pages: 2948-2972
Publication
First Author: Shibata M
Year: 2021
Journal: Nature
Title: Regulation of prefrontal patterning and connectivity by retinoic acid.
Volume: 598
Issue: 7881
Pages: 483-488
Publication
First Author: Lanier J
Year: 2009
Journal: Dev Dyn
Title: Brn3a regulates the transition from neurogenesis to terminal differentiation and represses non-neural gene expression in the trigeminal ganglion.
Volume: 238
Issue: 12
Pages: 3065-79
Publication
First Author: Metzakopian E
Year: 2012
Journal: Development
Title: Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors.
Volume: 139
Issue: 14
Pages: 2625-34
Publication  
First Author: Moreau MX
Year: 2021
Journal: Development
Title: Single-cell transcriptomics of the early developing mouse cerebral cortex disentangle the spatial and temporal components of neuronal fate acquisition.
Volume: 148
Issue: 14
Publication  
First Author: Telley L
Year: 2019
Journal: Science
Title: Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.
Volume: 364
Issue: 6440
Publication
First Author: Gu Z
Year: 2015
Journal: PLoS One
Title: Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Volume: 10
Issue: 3
Pages: e0121550
Publication
First Author: Perera SN
Year: 2020
Journal: Glia
Title: Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach.
Volume: 68
Issue: 12
Pages: 2550-2584
Publication
First Author: Tamplin OJ
Year: 2011
Journal: Dev Biol
Title: Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.
Volume: 360
Issue: 2
Pages: 415-25
Publication      
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Allele  
Name: huntingtin; targeted mutation 1, Peter J Detloff
Allele Type: Targeted
Interaction Experiment
Description: L1 and CHL1 Cooperate in Thalamocortical Axon Targeting.
Publication
First Author: Kim W
Year: 2018
Journal: Mol Neurodegener
Title: BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.
Volume: 13
Issue: 1
Pages: 6
Publication
First Author: Rudra S
Year: 2013
Journal: PLoS One
Title: Chl1 DNA helicase regulates Scc2 deposition specifically during DNA-replication in Saccharomyces cerevisiae.
Volume: 8
Issue: 9
Pages: e75435
Interaction Experiment
Description: Neural recognition molecules CHL1 and NB-3 regulate apical dendrite orientation in the neocortex via PTP alpha.
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: L Holloway S
Year: 2000
Journal: Nucleic Acids Res
Title: CHL1 is a nuclear protein with an essential ATP binding site that exhibits a size-dependent effect on chromosome segregation.
Volume: 28
Issue: 16
Pages: 3056-64
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Petronczki M
Year: 2004
Journal: J Cell Sci
Title: Sister-chromatid cohesion mediated by the alternative RF-CCtf18/Dcc1/Ctf8, the helicase Chl1 and the polymerase-alpha-associated protein Ctf4 is essential for chromatid disjunction during meiosis II.
Volume: 117
Issue: Pt 16
Pages: 3547-59
Publication
First Author: Inoue A
Year: 2007
Journal: Cell Cycle
Title: Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.
Volume: 6
Issue: 13
Pages: 1646-54
Publication
First Author: Hirota Y
Year: 2000
Journal: Nucleic Acids Res
Title: Characterization of the enzymatic activity of hChlR1, a novel human DNA helicase.
Volume: 28
Issue: 4
Pages: 917-24
Publication
First Author: Amann J
Year: 1997
Journal: J Biol Chem
Title: Characterization of putative human homologues of the yeast chromosome transmission fidelity gene, CHL1.
Volume: 272
Issue: 6
Pages: 3823-32
Protein Domain
Type: Family
Description: CHL1 DNA helicase plays a critical role in sister chromatid cohesion []. DDX11 is the mammalian homologue of the yeast CHL1. DDX11 is a DNA helicase involved in cellular proliferation []. In humans a second homologue has been identified, DDX12 []. DDX11 translocates on single-stranded DNA in the 5' to 3' direction in the presence of ATP and, to a lesser extent, dATP. Its unwinding activity requires a 5'-single-stranded region for helicase loading, since flush-ended duplex structures do not support unwinding []. Defects in DDX11 are the cause of Warsaw breakage syndrome (WBRS), a syndrome characterised by severe microcephaly, growth retardation, facial dysmorphism and abnormal skin pigmentation [].
Publication
First Author: Huang Z
Year: 2016
Journal: EMBO J
Title: NB-3 signaling mediates the cross-talk between post-traumatic spinal axons and scar-forming cells.
Volume: 35
Issue: 16
Pages: 1745-65
Publication
First Author: Kizuka Y
Year: 2015
Journal: EMBO Mol Med
Title: An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease.
Volume: 7
Issue: 2
Pages: 175-89
Publication
First Author: Sengül GF
Year: 2024
Journal: Biochim Biophys Acta Mol Cell Res
Title: Hsc70 phosphorylation patterns and calmodulin regulate AP2 Clathrin-Coated-Vesicle life span for cell adhesion protein transport.
Volume: 1871
Issue: 1
Pages: 119611