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Search results 1 to 100 out of 208 for Fasn

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Category: Publication
Type Details Score
Publication
First Author: Gong Z
Year: 2023
Journal: Nat Commun
Title: CircRREB1 mediates lipid metabolism related senescent phenotypes in chondrocytes through FASN post-translational modifications.
Volume: 14
Issue: 1
Pages: 5242
Publication
First Author: Fafián-Labora J
Year: 2019
Journal: Cell Death Dis
Title: FASN activity is important for the initial stages of the induction of senescence.
Volume: 10
Issue: 4
Pages: 318
Publication
First Author: Zhang M
Year: 2020
Journal: Biochem Biophys Res Commun
Title: MicroRNA-103 represses hepatic de novo lipogenesis and alleviates NAFLD via targeting FASN and SCD1.
Volume: 524
Issue: 3
Pages: 716-722
Publication
First Author: Xie W
Year: 2019
Journal: Biochem Biophys Res Commun
Title: METTL3 inhibits hepatic insulin sensitivity via N6-methyladenosine modification of Fasn mRNA and promoting fatty acid metabolism.
Volume: 518
Issue: 1
Pages: 120-126
Publication
First Author: Bastos DC
Year: 2021
Journal: J Pathol
Title: Genetic ablation of FASN attenuates the invasive potential of prostate cancer driven by Pten loss.
Volume: 253
Issue: 3
Pages: 292-303
Publication  
First Author: Matsukawa T
Year: 2023
Journal: JCI Insight
Title: Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models.
Volume: 8
Issue: 17
Publication
First Author: Jeon BN
Year: 2012
Journal: J Lipid Res
Title: Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter.
Volume: 53
Issue: 4
Pages: 755-66
Publication
First Author: Knobloch M
Year: 2013
Journal: Nature
Title: Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis.
Volume: 493
Issue: 7431
Pages: 226-30
Publication
First Author: Rowland LA
Year: 2023
Journal: Nat Commun
Title: De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics.
Volume: 14
Issue: 1
Pages: 1362
Publication
First Author: Suburu J
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Fatty acid synthase is required for mammary gland development and milk production during lactation.
Volume: 306
Issue: 10
Pages: E1132-43
Publication
First Author: Bruning U
Year: 2018
Journal: Cell Metab
Title: Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation.
Volume: 28
Issue: 6
Pages: 866-880.e15
Publication
First Author: Montani L
Year: 2018
Journal: J Cell Biol
Title: De novo fatty acid synthesis by Schwann cells is essential for peripheral nervous system myelination.
Volume: 217
Issue: 4
Pages: 1353-1368
Publication
First Author: Che L
Year: 2017
Journal: Cell Cycle
Title: Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.
Volume: 16
Issue: 6
Pages: 499-507
Publication
First Author: Carroll RG
Year: 2018
Journal: J Biol Chem
Title: An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation.
Volume: 293
Issue: 15
Pages: 5509-5521
Publication
First Author: Jung MY
Year: 2018
Journal: FASEB J
Title: Fatty acid synthase is required for profibrotic TGF-β signaling.
Volume: 32
Issue: 7
Pages: 3803-3815
Publication
First Author: Guilherme A
Year: 2017
Journal: Mol Metab
Title: Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming.
Volume: 6
Issue: 8
Pages: 781-796
Publication
First Author: Cao K
Year: 2023
Journal: J Pathol
Title: Glycolysis and de novo fatty acid synthesis cooperatively regulate pathological vascular smooth muscle cell phenotypic switching and neointimal hyperplasia.
Volume: 259
Issue: 4
Pages: 388-401
Publication
First Author: Avraham O
Year: 2020
Journal: Nat Commun
Title: Satellite glial cells promote regenerative growth in sensory neurons.
Volume: 11
Issue: 1
Pages: 4891
Publication    
First Author: Dimas P
Year: 2019
Journal: Elife
Title: CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes.
Volume: 8
Publication
First Author: Bueno MJ
Year: 2019
Journal: Nat Commun
Title: Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells.
Volume: 10
Issue: 1
Pages: 5011
Publication
First Author: Worthmann A
Year: 2024
Journal: Nat Commun
Title: Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use.
Volume: 15
Issue: 1
Pages: 45
Publication
First Author: Nishi-Tatsumi M
Year: 2017
Journal: FEBS Lett
Title: A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.
Volume: 591
Issue: 7
Pages: 965-978
Publication
First Author: Liu B
Year: 2018
Journal: Nat Commun
Title: Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.
Volume: 9
Issue: 1
Pages: 4770
Publication
First Author: Young KE
Year: 2017
Journal: J Leukoc Biol
Title: Fatty acid synthase regulates the pathogenicity of Th17 cells.
Volume: 102
Issue: 5
Pages: 1229-1235
Publication
First Author: Wei X
Year: 2016
Journal: Nature
Title: Fatty acid synthesis configures the plasma membrane for inflammation in diabetes.
Volume: 539
Issue: 7628
Pages: 294-298
Publication  
First Author: Drury J
Year: 2022
Journal: Int J Mol Sci
Title: Tissue-Specific Downregulation of Fatty Acid Synthase Suppresses Intestinal Adenoma Formation via Coordinated Reprograming of Transcriptome and Metabolism in the Mouse Model of Apc-Driven Colorectal Cancer.
Volume: 23
Issue: 12
Publication
First Author: Bhatia B
Year: 2011
Journal: Oncogene
Title: Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma.
Volume: 30
Issue: 4
Pages: 410-22
Publication    
First Author: Plataki M
Year: 2019
Journal: JCI Insight
Title: Fatty acid synthase downregulation contributes to acute lung injury in murine diet-induced obesity.
Volume: 5
Publication  
First Author: Gonzalez-Bohorquez D
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: FASN-dependent de novo lipogenesis is required for brain development.
Volume: 119
Issue: 2
Publication
First Author: Bowers M
Year: 2020
Journal: Cell Stem Cell
Title: FASN-Dependent Lipid Metabolism Links Neurogenic Stem/Progenitor Cell Activity to Learning and Memory Deficits.
Volume: 27
Issue: 1
Pages: 98-109.e11
Publication
First Author: Di Vizio D
Year: 2007
Journal: Cancer Biol Ther
Title: Caveolin-1 is required for the upregulation of fatty acid synthase (FASN), a tumor promoter, during prostate cancer progression.
Volume: 6
Issue: 8
Pages: 1263-8
Publication
First Author: Li L
Year: 2016
Journal: Hepatology
Title: Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans.
Volume: 63
Issue: 6
Pages: 1900-13
Publication
First Author: Moon JS
Year: 2015
Journal: J Clin Invest
Title: UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis.
Volume: 125
Issue: 2
Pages: 665-80
Publication  
First Author: Hu J
Year: 2016
Journal: Sci Rep
Title: Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.
Volume: 6
Pages: 20484
Publication
First Author: Abd Alla J
Year: 2016
Journal: J Biol Chem
Title: Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice.
Volume: 291
Issue: 6
Pages: 2583-600
Publication
First Author: Antony N
Year: 2013
Journal: PLoS One
Title: cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells.
Volume: 8
Issue: 4
Pages: e59763
Publication
First Author: Paulauskis JD
Year: 1989
Journal: Biochem Biophys Res Commun
Title: Structure of mouse fatty acid synthase mRNA. Identification of the two NADPH binding sites.
Volume: 158
Issue: 3
Pages: 690-5
Publication
First Author: Razani B
Year: 2011
Journal: J Biol Chem
Title: Fatty acid synthase modulates homeostatic responses to myocardial stress.
Volume: 286
Issue: 35
Pages: 30949-61
Publication
First Author: Henriques F
Year: 2020
Journal: Cell Rep
Title: Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis.
Volume: 32
Issue: 5
Pages: 107998
Publication
First Author: Chirala SS
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero.
Volume: 100
Issue: 11
Pages: 6358-63
Publication
First Author: Funai K
Year: 2013
Journal: J Clin Invest
Title: Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling.
Volume: 123
Issue: 3
Pages: 1229-40
Publication
First Author: Chakravarthy MV
Year: 2009
Journal: J Lipid Res
Title: Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation.
Volume: 50
Issue: 4
Pages: 630-40
Publication
First Author: Shimokawa T
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides.
Volume: 99
Issue: 1
Pages: 66-71
Publication
First Author: Paulauskis JD
Year: 1988
Journal: J Biol Chem
Title: Cloning and expression of mouse fatty acid synthase and other specific mRNAs. Developmental and hormonal regulation in 3T3-L1 cells.
Volume: 263
Issue: 15
Pages: 7049-54
Publication
First Author: Semenkovich CF
Year: 1995
Journal: J Lipid Res
Title: Human fatty acid synthase mRNA: tissue distribution, genetic mapping, and kinetics of decay after glucose deprivation.
Volume: 36
Issue: 7
Pages: 1507-21
Publication
First Author: Schmid B
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Inhibition of fatty acid synthase prevents preadipocyte differentiation.
Volume: 328
Issue: 4
Pages: 1073-82
Publication
First Author: Schneider JG
Year: 2010
Journal: J Biol Chem
Title: Macrophage fatty-acid synthase deficiency decreases diet-induced atherosclerosis.
Volume: 285
Issue: 30
Pages: 23398-409
Publication
First Author: Lodhi IJ
Year: 2012
Journal: Cell Metab
Title: Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARγ activation to decrease diet-induced obesity.
Volume: 16
Issue: 2
Pages: 189-201
Publication
First Author: Wei X
Year: 2012
Journal: Cell Host Microbe
Title: Fatty acid synthase modulates intestinal barrier function through palmitoylation of mucin 2.
Volume: 11
Issue: 2
Pages: 140-52
Publication
First Author: Lodhi IJ
Year: 2015
Journal: Cell Metab
Title: Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.
Volume: 21
Issue: 1
Pages: 51-64
Publication
First Author: Lodhi IJ
Year: 2015
Journal: Cell Metab
Title: Acute ether lipid deficiency affects neutrophil biology in mice.
Volume: 21
Issue: 5
Pages: 652-3
Publication
First Author: Wei J
Year: 1996
Journal: Genomics
Title: Cloning a cDNA for carbonyl reductase (Cbr) from mouse cerebellum: murine genes that express cbr map to chromosomes 16 and 11.
Volume: 34
Issue: 1
Pages: 147-8
Publication
First Author: Chakravarthy MV
Year: 2005
Journal: Cell Metab
Title: "New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis.
Volume: 1
Issue: 5
Pages: 309-22
Publication
First Author: Chakravarthy MV
Year: 2007
Journal: J Clin Invest
Title: Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.
Volume: 117
Issue: 9
Pages: 2539-52
Publication
First Author: Wu M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes.
Volume: 108
Issue: 13
Pages: 5378-83
Publication
First Author: Latasa MJ
Year: 2003
Journal: Mol Cell Biol
Title: Occupancy and function of the -150 sterol regulatory element and -65 E-box in nutritional regulation of the fatty acid synthase gene in living animals.
Volume: 23
Issue: 16
Pages: 5896-907
Publication
First Author: Moriya H
Year: 2011
Journal: Arch Biochem Biophys
Title: Secretion of three enzymes for fatty acid synthesis into mouse milk in association with fat globules, and rapid decrease of the secreted enzymes by treatment with rapamycin.
Volume: 508
Issue: 1
Pages: 87-92
Publication
First Author: Tang W
Year: 1997
Journal: Mamm Genome
Title: Murine Hn1 on chromosome 11 is expressed in hemopoietic and brain tissues.
Volume: 8
Issue: 9
Pages: 695-6
Publication
First Author: Najjar SM
Year: 2005
Journal: Cell Metab
Title: Insulin acutely decreases hepatic fatty acid synthase activity.
Volume: 2
Issue: 1
Pages: 43-53
Publication
First Author: Ridsdale R
Year: 2004
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Surfactant lipid synthesis and lamellar body formation in glycogen-laden type II cells.
Volume: 287
Issue: 4
Pages: L743-51
Publication
First Author: Hsu DK
Year: 1993
Journal: Biochem Biophys Res Commun
Title: Fibroblast growth factor-1 induces phosphofructokinase, fatty acid synthase and Ca(2+)-ATPase mRNA expression in NIH 3T3 cells.
Volume: 197
Issue: 3
Pages: 1483-91
Publication
First Author: Brody SL
Year: 1997
Journal: Genomics
Title: Structural characterization of the mouse Hfh4 gene, a developmentally regulated forkhead family member.
Volume: 45
Issue: 3
Pages: 509-18
Publication
First Author: Chung KP
Year: 2019
Journal: Nat Commun
Title: Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.
Volume: 10
Issue: 1
Pages: 3390
Publication
First Author: Méndez-Lucas A
Year: 2020
Journal: Nat Metab
Title: Identifying strategies to target the metabolic flexibility of tumours.
Volume: 2
Issue: 4
Pages: 335-350
Publication
First Author: Ghimire S
Year: 2021
Journal: PLoS One
Title: PEG3 controls lipogenesis through ACLY.
Volume: 16
Issue: 5
Pages: e0252354
Publication
First Author: Goncalves MD
Year: 2019
Journal: Science
Title: High-fructose corn syrup enhances intestinal tumor growth in mice.
Volume: 363
Issue: 6433
Pages: 1345-1349
Publication
First Author: Wei X
Year: 2011
Journal: J Biol Chem
Title: De novo lipogenesis maintains vascular homeostasis through endothelial nitric-oxide synthase (eNOS) palmitoylation.
Volume: 286
Issue: 4
Pages: 2933-45
Publication
First Author: Patel DD
Year: 2001
Journal: J Lipid Res
Title: Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice.
Volume: 42
Issue: 3
Pages: 328-37
Publication
First Author: Hebbachi AM
Year: 2008
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor alpha deficiency abolishes the response of lipogenic gene expression to re-feeding: restoration of the normal response by activation of liver X receptor alpha.
Volume: 283
Issue: 8
Pages: 4866-76
Publication
First Author: Choe SS
Year: 2007
Journal: Diabetes
Title: Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells.
Volume: 56
Issue: 6
Pages: 1534-43
Publication
First Author: Casado M
Year: 1999
Journal: J Biol Chem
Title: Essential role in vivo of upstream stimulatory factors for a normal dietary response of the fatty acid synthase gene in the liver.
Volume: 274
Issue: 4
Pages: 2009-13
Publication
First Author: Moran JL
Year: 1999
Journal: Mamm Genome
Title: Genomic structure, mapping, and expression analysis of the mammalian Lunatic, Manic, and Radical fringe genes.
Volume: 10
Issue: 6
Pages: 535-41
Publication
First Author: Takeuchi Y
Year: 2016
Journal: Cell Rep
Title: KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.
Volume: 16
Issue: 9
Pages: 2373-86
Publication
First Author: Kaltenecker D
Year: 2017
Journal: Diabetologia
Title: Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice.
Volume: 60
Issue: 2
Pages: 296-305
Publication
First Author: Martins L
Year: 2016
Journal: Cell Rep
Title: A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance.
Volume: 16
Issue: 8
Pages: 2231-2242
Publication
First Author: Muglia LJ
Year: 1999
Journal: Am J Respir Cell Mol Biol
Title: Proliferation and differentiation defects during lung development in corticotropin-releasing hormone-deficient mice.
Volume: 20
Issue: 2
Pages: 181-8
Publication
First Author: Rajan L
Year: 1997
Journal: Mamm Genome
Title: An MMTV integration site maps near the distal end of mouse chromosome 11.
Volume: 8
Issue: 4
Pages: 295-6
Publication
First Author: Hasegawa S
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Acetoacetyl-CoA synthetase is essential for normal neuronal development.
Volume: 427
Issue: 2
Pages: 398-403
Publication
First Author: Stone SJ
Year: 2004
Journal: J Biol Chem
Title: Lipopenia and skin barrier abnormalities in DGAT2-deficient mice.
Volume: 279
Issue: 12
Pages: 11767-76
Publication
First Author: Zhang Y
Year: 2016
Journal: Am J Pathol
Title: Inhibition of Poly(ADP-Ribose) Polymerase-1 Protects Chronic Alcoholic Liver Injury.
Volume: 186
Issue: 12
Pages: 3117-3130
Publication
First Author: Jang Y
Year: 2021
Journal: Genes Dev
Title: MED1 is a lipogenesis coactivator required for postnatal adipose expansion.
Volume: 35
Issue: 9-10
Pages: 713-728
Publication
First Author: DiTommaso T
Year: 2014
Journal: PLoS Genet
Title: Keratin 76 is required for tight junction function and maintenance of the skin barrier.
Volume: 10
Issue: 10
Pages: e1004706
Publication  
First Author: Habeos GI
Year: 2022
Journal: Antioxidants (Basel)
Title: Maternal Calorie Restriction Induces a Transcriptional Cytoprotective Response in Embryonic Liver Partially Dependent on Nrf2.
Volume: 11
Issue: 11
Publication
First Author: Lee K
Year: 2003
Journal: J Clin Invest
Title: Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor-1 (Pref-1).
Volume: 111
Issue: 4
Pages: 453-61
Publication
First Author: Onodera K
Year: 1999
Journal: J Biol Chem
Title: Characterization of the murine mafF gene.
Volume: 274
Issue: 30
Pages: 21162-9
Publication
First Author: Myöhänen S
Year: 1994
Journal: DNA Seq
Title: Nucleotide sequence of mouse spermidine synthase cDNA.
Volume: 4
Issue: 5
Pages: 343-6
Publication
First Author: Chen L
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the AMPK-TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion.
Volume: 113
Issue: 26
Pages: 7219-24
Publication
First Author: Clar J
Year: 2014
Journal: Kidney Int
Title: Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy.
Volume: 86
Issue: 4
Pages: 747-56
Publication
First Author: Chakravarthy MV
Year: 2008
Journal: Diabetes
Title: Decreased fetal size is associated with beta-cell hyperfunction in early life and failure with age.
Volume: 57
Issue: 10
Pages: 2698-707
Publication
First Author: Testini C
Year: 2019
Journal: EMBO Rep
Title: Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2.
Volume: 20
Issue: 11
Pages: e47845
Publication
First Author: Thoren LA
Year: 2010
Journal: PLoS One
Title: UPF2 is a critical regulator of liver development, function and regeneration.
Volume: 5
Issue: 7
Pages: e11650
Publication
First Author: Shimano H
Year: 1996
Journal: J Clin Invest
Title: Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.
Volume: 98
Issue: 7
Pages: 1575-84
Publication
First Author: Vergnes L
Year: 2016
Journal: J Lipid Res
Title: SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression.
Volume: 57
Issue: 3
Pages: 410-21
Publication  
First Author: Kobayashi K
Year: 2023
Journal: Life Sci Alliance
Title: Feto-maternal cholesterol transport regulated by β-Klotho-FGF15 axis is essential for fetal growth.
Volume: 6
Issue: 10
Publication  
First Author: Guo CG
Year: 2023
Journal: Mol Metab
Title: Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion.
Volume: 79
Pages: 101847
Publication
First Author: Coles GL
Year: 2015
Journal: PLoS Genet
Title: KIF7 Controls the Proliferation of Cells of the Respiratory Airway through Distinct Microtubule Dependent Mechanisms.
Volume: 11
Issue: 10
Pages: e1005525
Publication
First Author: Beigneux AP
Year: 2004
Journal: J Biol Chem
Title: ATP-citrate lyase deficiency in the mouse.
Volume: 279
Issue: 10
Pages: 9557-64
Publication
First Author: Banks AS
Year: 2011
Journal: Cell Metab
Title: Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice.
Volume: 14
Issue: 5
Pages: 587-97
Publication
First Author: Bose SK
Year: 2016
Journal: Endocrinology
Title: Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.
Volume: 157
Issue: 12
Pages: 4943-4960
Publication
First Author: Kahraman S
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring.
Volume: 307
Issue: 10
Pages: E906-18