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Search results 101 to 192 out of 192 for Rab4a

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0.024s
Type Details Score
GXD Expression  
Probe: MGI:4423910
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827583
Age: embryonic day 14.5
Image: euxassay_009638_06
Specimen Label: euxassay_009638_06
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4423910
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827583
Age: embryonic day 14.5
Image: euxassay_009638_07
Specimen Label: euxassay_009638_07
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4423910
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827583
Age: embryonic day 14.5
Image: euxassay_009638_16
Specimen Label: euxassay_009638_16
Detected: true
Specimen Num: 11
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691033
Age: postnatal adult
Image: MRC Harwell_1567043
Specimen Label: MRC Harwell_1567043
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691033
Age: postnatal adult
Image: MRC Harwell_1500596
Specimen Label: MRC Harwell_1500596
Detected: true
Specimen Num: 16
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691033
Age: postnatal adult
Image: MRC Harwell_1567044
Specimen Label: MRC Harwell_1567044
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691033
Age: postnatal adult
Image: MRC Harwell_1567043
Specimen Label: MRC Harwell_1567043
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6711819
Assay Type: Immunohistochemistry
Annotation Date: 2021-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:6711984
Age: embryonic day 6.5
Image: S3 -/-
Note: Expressed in a resident of subdomains of early endosomes, existed separately with Dkk1.
Specimen Label: S3 -/-
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6711819
Assay Type: Immunohistochemistry
Annotation Date: 2021-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:6711984
Age: embryonic day 6.5
Image: S3 WT
Note: Expressed in a resident of subdomains of early endosomes, existed in close proximity with Dkk1.
Specimen Label: S3 WT
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691033
Age: postnatal adult
Image: MRC Harwell_1567049
Specimen Label: MRC Harwell_1567049
Detected: true
Specimen Num: 10
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691033
Age: postnatal adult
Image: MRC Harwell_1567046
Specimen Label: MRC Harwell_1567046
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691033
Age: postnatal adult
Image: MRC Harwell_1567048
Specimen Label: MRC Harwell_1567048
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691033
Age: postnatal adult
Image: MRC Harwell_1567050
Specimen Label: MRC Harwell_1567050
Detected: true
Specimen Num: 11
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691033
Age: postnatal adult
Image: MRC Harwell_1567049
Specimen Label: MRC Harwell_1567049
Detected: true
Specimen Num: 10
GXD Expression
Probe: MGI:7541042
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:381337
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7541131
Age: embryonic day 5.5
Image: 5c/d/e
Note: Expressed in a dot-like pattern.
Specimen Label: 5c/d/e
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7541042
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:381337
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7541131
Age: embryonic day 5.5
Image: 5g/h/i
Note: Diminished expression and exhibited a smear distribution pattern in mutant cells.
Specimen Label: 5g/h/i
Detected: true
Specimen Num: 2
Publication
First Author: Ikeda H
Year: 1996
Journal: Biochem Mol Biol Int
Title: Isolation and sequence determination of cDNA encoding mouse rab 4 and candidate approach for the beige mutation in mice.
Volume: 40
Issue: 4
Pages: 647-51
Publication
First Author: Filipeanu CM
Year: 2006
Journal: J Biol Chem
Title: Enhancement of the recycling and activation of beta-adrenergic receptor by Rab4 GTPase in cardiac myocytes.
Volume: 281
Issue: 16
Pages: 11097-103
Publication
First Author: Cormont M
Year: 2003
Journal: Traffic
Title: CD2AP/CMS regulates endosome morphology and traffic to the degradative pathway through its interaction with Rab4 and c-Cbl.
Volume: 4
Issue: 2
Pages: 97-112
Publication
First Author: Cormont M
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic.
Volume: 98
Issue: 4
Pages: 1637-42
Publication
First Author: Yuasa K
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Trafficking of cGMP-dependent protein kinase II via interaction with Rab11.
Volume: 374
Issue: 3
Pages: 522-6
Publication
First Author: Barbosa MD
Year: 1995
Journal: Genomics
Title: The Rab protein family: genetic mapping of six Rab genes in the mouse.
Volume: 30
Issue: 3
Pages: 439-44
Publication
First Author: Imamura T
Year: 2003
Journal: Mol Cell Biol
Title: Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesin.
Volume: 23
Issue: 14
Pages: 4892-900
Publication
First Author: Schindler C
Year: 2015
Journal: Nat Cell Biol
Title: EARP is a multisubunit tethering complex involved in endocytic recycling.
Volume: 17
Issue: 5
Pages: 639-50
Publication  
First Author: Matsuda S
Year: 2013
Journal: Nat Commun
Title: Stargazin regulates AMPA receptor trafficking through adaptor protein complexes during long-term depression.
Volume: 4
Pages: 2759
Publication
First Author: Chamberlain MD
Year: 2004
Journal: J Biol Chem
Title: The p85alpha subunit of phosphatidylinositol 3'-kinase binds to and stimulates the GTPase activity of Rab proteins.
Volume: 279
Issue: 47
Pages: 48607-14
Publication
First Author: Usami Y
Year: 2011
Journal: Neurobiol Dis
Title: DJ-1 associates with synaptic membranes.
Volume: 43
Issue: 3
Pages: 651-62
Publication
First Author: Lucitti JL
Year: 2016
Journal: Stroke
Title: Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke.
Volume: 47
Issue: 12
Pages: 3022-3031
Publication
First Author: Banks GT
Year: 2011
Journal: J Neurosci
Title: Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse.
Volume: 31
Issue: 14
Pages: 5483-94
Publication
First Author: Sun-Wada GH
Year: 2021
Journal: Sci Rep
Title: Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm.
Volume: 11
Issue: 1
Pages: 19355
Publication
First Author: Peng C
Year: 2012
Journal: J Biol Chem
Title: Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.
Volume: 287
Issue: 39
Pages: 32861-73
Publication
First Author: Toonen RF
Year: 2005
Journal: J Neurochem
Title: Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation.
Volume: 93
Issue: 6
Pages: 1393-400
Publication
First Author: Kawamura N
Year: 2020
Journal: Cell Rep
Title: Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism.
Volume: 31
Issue: 10
Pages: 107733
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication        
First Author: Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas
Year: 2023
Title: TreeGrafter-generated GO annotations
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication
First Author: Bielli A
Year: 2001
Journal: Biochem Biophys Res Commun
Title: The small GTPase Rab4A interacts with the central region of cytoplasmic dynein light intermediate chain-1.
Volume: 281
Issue: 5
Pages: 1141-53
Allele
Name: RAB4A, member RAS oncogene family; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Kachhap SK
Year: 2007
Journal: PLoS One
Title: The N-Myc down regulated Gene1 (NDRG1) Is a Rab4a effector involved in vesicular recycling of E-cadherin.
Volume: 2
Issue: 9
Pages: e844
Publication
First Author: Huber SK
Year: 2005
Journal: FEBS Lett
Title: High resolution crystal structures of human Rab4a in its active and inactive conformations.
Volume: 579
Issue: 13
Pages: 2821-9
Publication
First Author: Karlsson S
Year: 2006
Journal: Mol Biol Cell
Title: Loss of T-cell protein tyrosine phosphatase induces recycling of the platelet-derived growth factor (PDGF) beta-receptor but not the PDGF alpha-receptor.
Volume: 17
Issue: 11
Pages: 4846-55
Publication
First Author: Augustus AS
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Substrate uptake and metabolism are preserved in hypertrophic caveolin-3 knockout hearts.
Volume: 295
Issue: 2
Pages: H657-66
Publication  
First Author: Katsura KA
Year: 2014
Journal: Matrix Biol
Title: WDR72 models of structure and function: a stage-specific regulator of enamel mineralization.
Volume: 38
Pages: 48-58
Publication
First Author: Okuda T
Year: 2004
Journal: Mol Cell Biol
Title: Ndrg1-deficient mice exhibit a progressive demyelinating disorder of peripheral nerves.
Volume: 24
Issue: 9
Pages: 3949-56
Publication
First Author: Kalaydjieva L
Year: 2000
Journal: Am J Hum Genet
Title: N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom.
Volume: 67
Issue: 1
Pages: 47-58
Publication
First Author: Stein S
Year: 2004
Journal: J Biol Chem
Title: NDRG1 is necessary for p53-dependent apoptosis.
Volume: 279
Issue: 47
Pages: 48930-40
Protein Domain
Type: Family
Description: N-myc downstream regulated gene (NDRG) family members are characterised by an alpha/beta hydrolase-fold motif. NDRG proteins may function as tumour suppressors and may also play important roles in the development of neurological and electrophysiological diseases [, ]. This entry represents NDRG1. The C-terminal region of NDRG1 contains three 10-aa (GTRSRSHTSE) tandem repeats, which are absent in the other family members and may be crucial for its function. NDRG1 is implicated in placentation and is involved in the development of the urinary and reproductive organs of the embryos. NDRG1 also functions in mast cell inflammatory processes []. NDRG1 is expressed in Purkinje cells in the cerebellum and in the cytoplasm of myelinating Schwann cells in peripheral nerves []. NDRG1 has been links to several diseases, such as hereditary motor and sensory neuropathy-Lom (HMSNL) []and Schwann cell dysfunction []. The expression of NDRG1 is down-regulated in certain cancer types, but up-regulated in other cancer types. This suggests that NDRG1 has tissue-specific functions in various cancer types []. NDRG1 is necessary for p53-dependent apoptosis []. It is also a Rab4a effector involved in vesicular recycling of the adhesion molecule E-cadherin [].
Protein
Organism: Mus musculus/domesticus
Length: 53  
Fragment?: true
Publication
First Author: Hwang J
Year: 2011
Journal: J Biol Chem
Title: Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor.
Volume: 286
Issue: 14
Pages: 12450-60
Protein
Organism: Mus musculus/domesticus
Length: 394  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 394  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 394  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 394  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 155  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 394  
Fragment?: false
Publication
First Author: Melotte V
Year: 2010
Journal: FASEB J
Title: The N-myc downstream regulated gene (NDRG) family: diverse functions, multiple applications.
Volume: 24
Issue: 11
Pages: 4153-66