|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 601 to 690 out of 690 for Tardbp

<< First    < Previous  |  Next >    Last >>
0.024s

Categories

Hits by Strain

Hits by Category

Type Details Score
Genotype
Genotype
Symbol: Tg(Prnp-TARDBP)96Dwc/? Tg(Prnp-TARDBP*Q331K)31Dwc/?
Background: involves: C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
DO Term
DOID:0060201 | amyotrophic lateral sclerosis type 10
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(tetO-TARDBP*A315T)13Lmit/? Tg(Thy1-tTA)6Lmit/?
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Prnp-TARDBP*Q331K)103Dwc/?
Background: B6.Cg-Tg(Prnp-TARDBP*Q331K)103Dwc/J
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tardbp/Tardbp<+>
Background: involves: C57BL/6J
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tardbp/Tardbp Tg(SLC18A3-cre)Misa/?
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(TARDBP*A315T)#Jpj/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(TARDBP*G348C)#Jpj/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Thy1-TARDBP*)BOddo/Tg(Thy1-TARDBP*)BOddo
Background: C57BL/6-Tg(Thy1-TARDBP*)BOddo
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Allele
Tg(Prnp-TARDBP)1Koya | MGI:7382830
Name: transgene insertion 1, Koji Yamanaka
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Strain
MGI:6771207 | C57BL/6-Tardbp<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Publication
22029574 | J:179348
 
First Author: Xu YF
Year: 2011
Journal: Mol Neurodegener
Title: Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice.
Volume: 6
Pages: 73
•
•
•
•
•
Strain
MGI:7386798 | B6.Cg-Tg(Prnp-TARDBP)1Koya/Koya
Attribute String: congenic, mutant strain, transgenic
•
•
•
•
•
Allele
Tg(Prnp-TARDBP*R208)1Koya | MGI:7382863
Name: transgene insertion 1, Koji Yamanaka
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Allele
Tardbp<tm1(TARDBP*G348C/Venus)Okn> | MGI:5819107
Name: TAR DNA binding protein; targeted mutation 1, Hideyuki Okano
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tardbp<tm2(TARDBP*A382T/Venus)Okn> | MGI:5819108
Name: TAR DNA binding protein; targeted mutation 2, Hideyuki Okano
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tardbp<em1Smoc> | MGI:7292687
Name: TAR DNA binding protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Tg(Prnp-TARDBP*M337V)4Ptrc | MGI:5301818
Name: transgene insertion 4, Leonard Petrucelli
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tardbp<tm1.1Pcw> | MGI:4834273
Name: TAR DNA binding protein; targeted mutation 1.1, Philip C Wong
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Tg(Prnp-TARDBP)3cPtrc | MGI:5002476
Name: transgene insertion 3c, Leonard Petrucelli
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(Prnp-TARDBP*A315T)95Balo | MGI:4358722
Name: transgene insertion 95, Robert Baloh
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(Thy1-TARDBP)4Singh | MGI:4438490
Name: transgene insertion 4, Samir Kumar-Singh
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Allele
Tardbp<em1Rhbr> | MGI:6157626
Name: TAR DNA binding protein; endonuclease-mediated mutation 1, Robert Brown Jr
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
•
•
•
•
•
Publication
20133711 | J:157550
First Author: Wils H
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.
Volume: 107
Issue: 8
Pages: 3858-63
•
•
•
•
•
Publication
29787578 | J:263558
First Author: Scherz B
Year: 2018
Journal: PLoS One
Title: mTh1 driven expression of hTDP-43 results in typical ALS/FTLD neuropathological symptoms.
Volume: 13
Issue: 5
Pages: e0197674
•
•
•
•
•
Strain
MGI:7386799 | B6.Cg-Tg(Prnp-TARDBP*R208)1Koya/Koya
Attribute String: congenic, mutant strain, transgenic
•
•
•
•
•
Strain
MGI:5301828 | C57BL/6-Tg(Prnp-TARDBP*M337V)4Ptrc/J
Attribute String: coisogenic, transgenic, mutant strain
•
•
•
•
•
Publication
28335005 | J:250252
First Author: Gu J
Year: 2017
Journal: Nucleic Acids Res
Title: TDP-43 suppresses tau expression via promoting its mRNA instability.
Volume: 45
Issue: 10
Pages: 6177-6193
•
•
•
•
•
Allele
Tg(Krt8-TARDBP)#Say | MGI:6275553
Name: transgene insertion, Satoshi Yamashita
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Strain
MGI:5308204 | B6(SJL)-Tardbp<tm1.1Pcw>/J
Attribute String: mutant strain, targeted mutation
•
•
•
•
•
Genotype
Genotype
Symbol: Tardbp/Tardbp<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tardbp/Tardbp<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Transgene
MGI:5476817 | Tg(TARDBP*A315T)#Jpj
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
Transgene
MGI:4438487 | Tg(Thy1-TARDBP)6Singh
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
Transgene
MGI:5002478 | Tg(Prnp-TARDBP)3cPtrc
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
Transgene
MGI:4358721 | Tg(Prnp-TARDBP*A315T)95Balo
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
Transgene
MGI:4438486 | Tg(Thy1-TARDBP)4Singh
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
Transgene
MGI:5476818 | Tg(TARDBP*G348C)#Jpj
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
Transgene
MGI:5476814 | Tg(TARDBP)#Jpj
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
Transgene
MGI:5310798 | Tg(Thy1-TARDBP*)BOddo
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Prnp-TARDBP*A315T)95Balo/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Thy1-TARDBP)4Singh/Tg(Thy1-TARDBP)4Singh
Background: involves: C57BL/6J * SJL/J
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Thy1-TARDBP)4Singh/?
Background: involves: C57BL/6J * SJL/J
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Prnp-TARDBP)3cPtrc/Tg(Prnp-TARDBP)3cPtrc
Background: C57BL/6-Tg(Prnp-TARDBP)3cPtrc
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tardbp/Tardbp
Background: C57BL/6J-Tardbp
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Publication
29097807 | J:265116
First Author: Tsuiji H
Year: 2017
Journal: Sci Rep
Title: TDP-43 accelerates age-dependent degeneration of interneurons.
Volume: 7
Issue: 1
Pages: 14972
•
•
•
•
•
Allele
Tg(Prnp-Tardbp,-EGFP)19Zxu | MGI:6469530
Name: transgene insertion 19, Zuoshang Xu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
•
•
•
•
•
Strain
MGI:6469538 | FVB/NJ-Tg(Prnp-Tardbp,-EGFP)19Zxu/J
Attribute String: coisogenic, mutant strain, transgenic
•
•
•
•
•
Publication
35113871 | J:319624
First Author: Yang C
Year: 2022
Journal: PLoS One
Title: Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice.
Volume: 17
Issue: 2
Pages: e0255710
•
•
•
•
•
Strain
MGI:6405400 | B6(C3)-Tardbp<tm2.1Neas>
Attribute String: targeted mutation, mutant strain
•
•
•
•
•
Allele
Tardbp<em1Koya> | MGI:6405404
Name: TAR DNA binding protein; endonuclease-mediated mutation 1, Koji Yamanaka
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
•
•
•
•
•
Allele
Tardbp<tm1.1(TARDBP)Mdk> | MGI:7576944
Name: TAR DNA binding protein; targeted mutation 1.1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
•
•
•
•
•
Strain
MGI:4943773 | STOCK Tg(Prnp-TARDBP*A315T)23Jlel/J
Attribute String: mutant stock, transgenic
•
•
•
•
•
Strain
MGI:5319367 | B6SJL-Tg(Prnp-TARDBP*A315T)23Jlel/J
Attribute String: mutant stock, transgenic
•
•
•
•
•
Publication
31406156 | J:284842
First Author: Yamashita S
Year: 2019
Journal: Sci Rep
Title: CYLD dysregulation in pathogenesis of sporadic inclusion body myositis.
Volume: 9
Issue: 1
Pages: 11606
•
•
•
•
•
Strain
MGI:6405397 | B6(C3)-Tardbp<tm1.1Neas>
Attribute String: mutant strain, targeted mutation
•
•
•
•
•
Strain
MGI:5311109 | C57BL/6-Tg(Thy1-TARDBP*)BOddo
Attribute String: transgenic, mutant strain, coisogenic
•
•
•
•
•
Publication
22067910 | J:180165
First Author: Caccamo A
Year: 2012
Journal: Am J Pathol
Title: Cognitive decline typical of frontotemporal lobar degeneration in transgenic mice expressing the 25-kDa C-terminal fragment of TDP-43.
Volume: 180
Issue: 1
Pages: 293-302
•
•
•
•
•
Publication
26002100 | J:223932
First Author: Caccamo A
Year: 2015
Journal: Hum Mol Genet
Title: Reduced protein turnover mediates functional deficits in transgenic mice expressing the 25 kDa C-terminal fragment of TDP-43.
Volume: 24
Issue: 16
Pages: 4625-35
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Thy1-TARDBP*)BOddo/?
Background: C57BL/6-Tg(Thy1-TARDBP*)BOddo
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tardbp/Tardbp<+>
Background: B6(C3)-Tardbp
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tardbp/Tardbp<+>
Background: B6(C3)-Tardbp
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Publication
23238732 | J:192015
First Author: Swarup V
Year: 2012
Journal: J Neurosci
Title: Abnormal regenerative responses and impaired axonal outgrowth after nerve crush in TDP-43 transgenic mouse models of amyotrophic lateral sclerosis.
Volume: 32
Issue: 50
Pages: 18186-95
•
•
•
•
•
Strain
MGI:6405405 | C57BL/6J-Tardbp<em1Koya>
Attribute String: mutant strain, endonuclease-mediated mutation, coisogenic
•
•
•
•
•
Strain
MGI:7576946 | B6J.B6N-Tardbp<tm1.1(TARDBP)Mdk>/J
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Strain
MGI:7570390 | B6.129-Tardbp<em2.1(TARDBP)H>/H
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Strain
MGI:6690243 | B6;129-Tardbp<em2.1(TARDBP)H>/H
Attribute String: endonuclease-mediated mutation, mutant stock
•
•
•
•
•
Genotype
Genotype
Symbol: Tardbp/Tardbp
Background: C57BL/6J-Tardbp
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tardbp/Tardbp Tg(Stra8-icre)1Reb/?
Background: involves: C57BL/6 * FVB/NJ * SJL
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
HT Experiment
E-GEOD-54418 | Dysregulated Expression of Lipid Storage and Membrane Dynamics Factors in Tia1 Knock-Out Mouse Nervous Tissue
Series Id: GSE54418
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Publication
20621187 | J:165985
First Author: Stallings NR
Year: 2010
Journal: Neurobiol Dis
Title: Progressive motor weakness in transgenic mice expressing human TDP-43.
Volume: 40
Issue: 2
Pages: 404-14
•
•
•
•
•
Allele
Gt(ROSA)26Sor<tm1(TARDBP*M337V/Ypet)Tlbt> | MGI:5784728
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Kevin Talbot
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter
•
•
•
•
•
Genotype
Genotype
Symbol: Tardbp/Tardbp<+> Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129 * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tardbp/Tardbp Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129 * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tardbp/Tardbp
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tardbp/Tardbp<+>
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Publication
34160549 | J:342105
 
First Author: Ma S
Year: 2021
Journal: J Exp Med
Title: The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity.
Volume: 218
Issue: 8
•
•
•
•
•
Publication
21752789 | J:195184
First Author: Swarup V
Year: 2011
Journal: Brain
Title: Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments.
Volume: 134
Issue: Pt 9
Pages: 2610-26
•
•
•
•
•
Publication
26074815 | J:242808
 
First Author: Zhang F
Year: 2015
Journal: Front Aging Neurosci
Title: Miro1 deficiency in amyotrophic lateral sclerosis.
Volume: 7
Pages: 100
•
•
•
•
•
Strain
MGI:5784736 | B6;129S6-Gt(ROSA)26Sor<tm1(TARDBP*M337V/Ypet)Tlbt>/J
Attribute String: targeted mutation, mutant stock
•
•
•
•
•
Publication
30290270 | J:265544
 
First Author: Gordon D
Year: 2018
Journal: Neurobiol Dis
Title: Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.
Volume: 121
Pages: 148-162
•
•
•
•
•
Publication
32800996 | J:300568
 
First Author: Feneberg E
Year: 2020
Journal: Neurobiol Dis
Title: An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress.
Volume: 144
Pages: 105050
•
•
•
•
•
Publication
22230045 | J:184644
 
First Author: Audet JN
Year: 2012
Journal: Neuroscience
Title: Methylene blue administration fails to confer neuroprotection in two amyotrophic lateral sclerosis mouse models.
Volume: 209
Pages: 136-43
•
•
•
•
•
Publication
15672593 | J:94068
First Author: Stover CM
Year: 2004
Journal: Mamm Genome
Title: Organization of the MASP2 locus and its expression profile in mouse and rat.
Volume: 15
Issue: 11
Pages: 887-900
•
•
•
•
•
Publication
33038415 | J:301266
 
First Author: Sieverding K
Year: 2021
Journal: Exp Neurol
Title: Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43G298S transgenic mice.
Volume: 335
Pages: 113496
•
•
•
•
•
Publication
26437864 | J:245760
First Author: Ke YD
Year: 2015
Journal: Acta Neuropathol
Title: Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.
Volume: 130
Issue: 5
Pages: 661-78
•
•
•
•
•
Publication
35868558 | J:333877
First Author: Chaya T
Year: 2022
Journal: J Biol Chem
Title: Multiple knockout mouse and embryonic stem cell models reveal the role of miR-124a in neuronal maturation.
Volume: 298
Issue: 9
Pages: 102293
•
•
•
•
•
Publication
20702714 | J:163231
First Author: Xu YF
Year: 2010
Journal: J Neurosci
Title: Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice.
Volume: 30
Issue: 32
Pages: 10851-9
•
•
•
•
•
Publication
37158107 | J:338403
First Author: Cho KW
Year: 2023
Journal: Circulation
Title: Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis.
Volume: 147
Issue: 24
Pages: 1823-1842
•
•
•
•
•
Publication
32595447 | J:311244
 
First Author: Loeffler T
Year: 2020
Journal: Front Neurosci
Title: Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value.
Volume: 14
Pages: 579
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom