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Search results 1 to 1 out of 1 for Arid3b

Category restricted to ProteinDomain (x)

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Category: ProteinDomain
Type Details Score
Protein Domain
Type: Family
Description: This entry represents a group of transcription factors, including ARID3A/B/C from humans and protein dead ringer (Retn) from Drosophila melanogaster. ARID3A (also known as E2FBP1 or Bright) is involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation [, ]. ARID3B has been linked to malignant neuroblastoma []. Retn is regulator of the late development of longitudinal glia []. Mutations in the Drosophila retn gene lead to female behavioral defects and alter a limited set of neurons in the CNS. Retn also affects a male behavioral pathway activated by fruM [].