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Search results 301 to 340 out of 340 for Mmp3

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0.022s

Type

Details

Score

Strain

MGI:4839559 | STOCK H2<r> Mmp3<tm1Mrl>/Tac

Attribute String:

targeted mutation, mutant stock

•

Publication

23967200 | -

First Author:	Liu M
Year:	2013
Journal:	PLoS One
Title:	STAT3 regulates MMP3 in heme-induced endothelial cell apoptosis.
Volume:	8
Issue:	8
Pages:	e71366

•

Allele

Mmp3<em1Smoc> | MGI:7291119

Name:	matrix metallopeptidase 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

•

Strain

MGI:6429189 | C57BL/6J-Mmp3<em1Smoc>/Smoc

Attribute String:

coisogenic, mutant strain, endonuclease-mediated mutation

•

Allele

Tg(Wap-Mmp3)9Sym | MGI:2429538

Name:	transgene insertion 9, Carolyn J Sympson
Allele Type:	Transgenic
Attribute String:	Inserted expressed sequence

•

Allele

Tg(Wap-Mmp3)5Sym | MGI:2429539

Name:	transgene insertion 5, Carolyn J Sympson
Allele Type:	Transgenic
Attribute String:	Inserted expressed sequence

•

Publication

8978831 | J:155924

First Author:	Alexander CM
Year:	1996
Journal:	J Cell Biol
Title:	Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene.
Volume:	135
Issue:	6 Pt 1
Pages:	1669-77

•

Publication

10995766 | J:66382

First Author:	Rekdal C
Year:	2000
Journal:	J Biol Chem
Title:	The nuclear factor SPBP contains different functional domains and stimulates the activity of various transcriptional activators.
Volume:	275
Issue:	51
Pages:	40288-300

•

Publication

17913746 | -

First Author:	Sjøttem E
Year:	2007
Journal:	Nucleic Acids Res
Title:	The ePHD protein SPBP interacts with TopBP1 and together they co-operate to stimulate Ets1-mediated transcription.
Volume:	35
Issue:	19
Pages:	6648-62

•

Publication

21935435 | -

First Author:	Elvenes J
Year:	2011
Journal:	PLoS One
Title:	Pax6 represses androgen receptor-mediated transactivation by inhibiting recruitment of the coactivator SPBP.
Volume:	6
Issue:	9
Pages:	e24659

•

Publication

22081970 | -

First Author:	Darvekar S
Year:	2012
Journal:	Biochem J
Title:	Identification of two independent nucleosome-binding domains in the transcriptional co-activator SPBP.
Volume:	442
Issue:	1
Pages:	65-75

•

Protein Domain

IPR041972 | TCF-20_ePHD

Type:

Domain

Description:

Thisentry represents the C-terminal ePHD/ADD (ATRX-DNMT3-DNMT3L) domain of transcription factor 20 (TCF-20).The extended plant homeodomain (ePHD) zinc finger is characterised as Cys2HisCys5HisCys2His. TCF-20 (also known as SPBP) is involved in transcriptional activation of the MMP3 (matrix metalloprotease 3) promoter. It is strongly enriched on chromatin in interphase HeLa cells, and displays low nuclear mobility, and has been implicated in Smith-Magenis syndrome and Potocki-Lupski syndrome []. As a chromatin-binding protein, TCF-20 plays a role in the regulation of gene expression. It also functions as a transcriptional co-regulator that enhances or represses the transcriptional activity of certain transcription factors/cofactors, such as specificity protein 1 (Sp1), E twenty-six 1 (Ets1) [], paired box protein 6 (Pax6) [], small nuclear RING-finger (SNURF)/RNF4, c-Jun, androgen receptor (AR) and estrogen receptor alpha (ERalpha) []. TCF-20 contains an N-terminal transactivation domain, a novel DNA-binding domain with an AT-hook motif, three nuclear localization signals (NLSs) and a C-terminal ePHD/ADD domain.

•

Publication

36318619 | J:334702

First Author:	Murakami T
Year:	2022
Journal:	Sci Signal
Title:	Semaphorin 4D induces articular cartilage destruction and inflammation in joints by transcriptionally reprogramming chondrocytes.
Volume:	15
Issue:	758
Pages:	eabl5304

•

Publication

23756156 | J:308154

First Author:	Tsoutsman T
Year:	2013
Journal:	J Mol Cell Cardiol
Title:	CCN2 plays a key role in extracellular matrix gene expression in severe hypertrophic cardiomyopathy and heart failure.
Volume:	62

Pages:	164-78

•

Publication

21775709 | J:178361

First Author:	Georgescu SP
Year:	2011
Journal:	Am J Physiol Cell Physiol
Title:	Decreased metalloprotease 9 induction, cardiac fibrosis, and higher autophagy after pressure overload in mice lacking the transcriptional regulator p8.
Volume:	301
Issue:	5
Pages:	C1046-56

•

Publication

16192306 | J:102705

First Author:	Thangaraju M
Year:	2005
Journal:	Development
Title:	C/EBPdelta is a crucial regulator of pro-apoptotic gene expression during mammary gland involution.
Volume:	132
Issue:	21
Pages:	4675-85

•

Publication

23830916 | J:204114

First Author:	Erlandsson MC
Year:	2013
Journal:	Biochim Biophys Acta
Title:	Expression of metastasin S100A4 is essential for bone resorption and regulates osteoclast function.
Volume:	1833
Issue:	12
Pages:	2653-2663

•

Publication

21173249 | J:169006

First Author:	Österreicher CH
Year:	2011
Journal:	Proc Natl Acad Sci U S A
Title:	Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver.
Volume:	108
Issue:	1
Pages:	308-13

•

Publication

15879144 | J:99021

First Author:	Sweeney SE
Year:	2005
Journal:	J Immunol
Title:	Regulation of c-Jun phosphorylation by the I kappa B kinase-epsilon complex in fibroblast-like synoviocytes.
Volume:	174
Issue:	10
Pages:	6424-30

•

Publication

37887338 | J:342047

First Author:	Cullen AE
Year:	2023
Journal:	Cells
Title:	AKT Mediates Adiponectin-Dependent Regulation of VSMC Phenotype.
Volume:	12
Issue:	20

•

Publication

32295898 | J:286848

First Author:	Smeriglio P
Year:	2020
Journal:	Sci Transl Med
Title:	Inhibition of TET1 prevents the development of osteoarthritis and reveals the 5hmC landscape that orchestrates pathogenesis.
Volume:	12
Issue:	539

•

Publication

34830342 | J:336949

First Author:	Popovics P
Year:	2021
Journal:	Int J Mol Sci
Title:	Osteopontin Deficiency Ameliorates Prostatic Fibrosis and Inflammation.
Volume:	22
Issue:	22

•

Publication

33121932 | J:301378

First Author:	Gatticchi L
Year:	2021
Journal:	Biochim Biophys Acta Mol Cell Res
Title:	Tm7sf2 gene promotes adipocyte differentiation of mouse embryonic fibroblasts and improves insulin sensitivity.
Volume:	1868
Issue:	1
Pages:	118897

•

Publication

23264747 | J:200221

First Author:	Hoshino A
Year:	2013
Journal:	J Cell Sci
Title:	Roles of chemokine receptor CX3CR1 in maintaining murine bone homeostasis through the regulation of both osteoblasts and osteoclasts.
Volume:	126
Issue:	Pt 4
Pages:	1032-45

•

Publication

25267645 | J:216442

First Author:	Authier H
Year:	2014
Journal:	Proc Natl Acad Sci U S A
Title:	IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors.
Volume:	111
Issue:	41
Pages:	14794-9

•

Publication

12202125 | J:265957

First Author:	Flannelly J
Year:	2002
Journal:	Osteoarthritis Cartilage
Title:	Metalloproteinase and tissue inhibitor of metalloproteinase expression in the murine STR/ort model of osteoarthritis.
Volume:	10
Issue:	9
Pages:	722-33

•

Publication

31434493 | J:340182

First Author:	Harman JL
Year:	2019
Journal:	Arterioscler Thromb Vasc Biol
Title:	Epigenetic Regulation of Vascular Smooth Muscle Cells by Histone H3 Lysine 9 Dimethylation Attenuates Target Gene-Induction by Inflammatory Signaling.
Volume:	39
Issue:	11
Pages:	2289-2302

•

Publication

29330021 | J:264594

First Author:	Ono M
Year:	2018
Journal:	Matrix Biol
Title:	CCN4/WISP1 controls cutaneous wound healing by modulating proliferation, migration and ECM expression in dermal fibroblasts via α5β1 and TNFα.
Volume:	68-69

Pages:	533-546

•

Publication

32387619 | J:331818

First Author:	Li W
Year:	2020
Journal:	Exp Eye Res
Title:	Leucine-rich α-2-glycoprotein-1 promotes diabetic corneal epithelial wound healing and nerve regeneration via regulation of matrix metalloproteinases.
Volume:	196

Pages:	108060

•

Publication

22353730 | J:312800

First Author:	Lee SI
Year:	2012
Journal:	Arthritis Res Ther
Title:	Regulation of inflammatory arthritis by the upstream kinase mitogen activated protein kinase kinase 7 in the c-Jun N-terminal kinase pathway.
Volume:	14
Issue:	1
Pages:	R38

•

Publication

16916507 | J:112636

First Author:	Joshi PA
Year:	2006
Journal:	Dev Biol
Title:	Loss of Alx4, a stromally-restricted homeodomain protein, impairs mammary epithelial morphogenesis.
Volume:	297
Issue:	1
Pages:	284-94

•

Publication

34557202 | J:311198

First Author:	Liao YC
Year:	2021
Journal:	Front Immunol
Title:	NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.
Volume:	12

Pages:	743030

•

Publication

24278366 | J:209775

First Author:	Kondo Y
Year:	2013
Journal:	PLoS One
Title:	The Nogo-B-PirB axis controls macrophage-mediated vascular remodeling.
Volume:	8
Issue:	11
Pages:	e81019

•

Publication

31693860 | J:298523

First Author:	Lagosz KB
Year:	2020
Journal:	J Dent Res
Title:	HDAC3 Regulates Gingival Fibroblast Inflammatory Responses in Periodontitis.
Volume:	99
Issue:	1
Pages:	98-106

•

Publication

35479080 | J:325599

First Author:	Courties A
Year:	2022
Journal:	Front Immunol
Title:	Alpha-7 Nicotinic Receptor Dampens Murine Osteoblastic Response to Inflammation and Age-Related Osteoarthritis.
Volume:	13

Pages:	842538

•

Publication

26636652 | J:322957

First Author:	Shu CC
Year:	2016
Journal:	Arthritis Rheumatol
Title:	Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage Degradation, Synovitis, and Osteophyte Size in a Preclinical Model of Posttraumatic Osteoarthritis.
Volume:	68
Issue:	4
Pages:	868-79

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Protein

Q9EPQ8

Organism:	Mus musculus/domesticus
Length:	1987
Fragment?:	false

•

Protein

Q3U8L8

Organism:	Mus musculus/domesticus
Length:	419
Fragment?:	true

•

Protein

Q80U46

Organism:	Mus musculus/domesticus
Length:	1725
Fragment?:	true

•

Protein

Q66JM6

Organism:	Mus musculus/domesticus
Length:	1068
Fragment?:	true

•

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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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