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Search results 1 to 88 out of 88 for Rhbdf2

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Category: Publication
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Type Details Score
Publication
30694569 | J:273061
First Author: Geesala R
Year: 2019
Journal: J Leukoc Biol
Title: Loss of RHBDF2 results in an early-onset spontaneous murine colitis.
Volume: 105
Issue: 4
Pages: 767-781
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Publication
32094386 | J:289667
First Author: Levy R
Year: 2020
Journal: Sci Rep
Title: A genome-wide association study in mice reveals a role for Rhbdf2 in skeletal homeostasis.
Volume: 10
Issue: 1
Pages: 3286
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Publication
29116018 | J:250259
First Author: Hosur V
Year: 2017
Journal: BMC Res Notes
Title: Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease.
Volume: 10
Issue: 1
Pages: 573
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Publication
24825892 | J:211269
First Author: Hosur V
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.
Volume: 111
Issue: 21
Pages: E2200-9
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Publication
28655741 | J:244160
First Author: Hosur V
Year: 2017
Journal: Biol Open
Title: Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis.
Volume: 6
Issue: 8
Pages: 1174-1179
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Publication
28128203 | J:244670
 
First Author: Maruthappu T
Year: 2017
Journal: Nat Commun
Title: Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16.
Volume: 8
Pages: 14174
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Publication
29523849 | J:259696
First Author: Arcidiacono P
Year: 2018
Journal: Nat Commun
Title: p63 is a key regulator of iRHOM2 signalling in the keratinocyte stress response.
Volume: 9
Issue: 1
Pages: 1021
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Publication
25395669 | J:217394
First Author: Siggs OM
Year: 2014
Journal: Biol Open
Title: Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.
Volume: 3
Issue: 12
Pages: 1151-7
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Publication
28104813 | J:246731
First Author: Li X
Year: 2017
Journal: J Cell Sci
Title: Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.
Volume: 130
Issue: 5
Pages: 868-878
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Publication
23348744 | J:194483
First Author: Issuree PD
Year: 2013
Journal: J Clin Invest
Title: iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.
Volume: 123
Issue: 2
Pages: 928-32
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Publication
29491382 | J:262722
First Author: Kim JH
Year: 2018
Journal: Sci Rep
Title: Role of iRhom2 in intestinal ischemia-reperfusion-mediated acute lung injury.
Volume: 8
Issue: 1
Pages: 3797
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Publication
31918923 | J:285442
 
First Author: Badenes M
Year: 2020
Journal: Mol Metab
Title: Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis.
Volume: 31
Pages: 67-84
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Publication
- | J:213194
     
First Author: Zhang Z
Year: 2014
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for LosTNF
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Publication
33950315 | J:310482
First Author: Düsterhöft S
Year: 2021
Journal: Cell Mol Life Sci
Title: The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release.
Volume: 78
Issue: 11
Pages: 5015-5040
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Publication
- | J:220064
     
First Author: Zhang Z
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for LosTNF2 (Last updated March 25, 2015)
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Publication
29155878 | J:256003
First Author: Luo WW
Year: 2017
Journal: PLoS Pathog
Title: iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA.
Volume: 13
Issue: 11
Pages: e1006693
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Publication
10425919 | J:52604
First Author: Li SR
Year: 1999
Journal: Genet Res
Title: Uncv (uncovered): a new mutation causing hairloss on mouse chromosome 11.
Volume: 73
Issue: 3
Pages: 233-8
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12766798 | J:83830
First Author: Shi YZ
Year: 2003
Journal: Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
Title: A high-resolution genetic and physical map of a mouse coat abnormality locus (Uncv).
Volume: 35
Issue: 5
Pages: 397-402
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Publication
32135161 | J:291967
 
First Author: Skurski J
Year: 2020
Journal: Metabolism
Title: Loss of iRhom2 accelerates fat gain and insulin resistance in diet-induced obesity despite reduced adipose tissue inflammation.
Volume: 106
Pages: 154194
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Publication
31662486 | J:280798
 
First Author: Sundaram B
Year: 2019
Journal: Sci Signal
Title: iRhom2 inhibits bile duct obstruction-induced liver fibrosis.
Volume: 12
Issue: 605
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Publication
30097271 | J:271775
First Author: Chaohui C
Year: 2018
Journal: Biochem Biophys Res Commun
Title: iRhom2 promotes atherosclerosis through macrophage inflammation and induction of oxidative stress.
Volume: 503
Issue: 3
Pages: 1897-1904
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Publication
32180551 | J:304194
 
First Author: Xu M
Year: 2020
Journal: Mol Metab
Title: Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation.
Volume: 34
Pages: 112-123
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Publication
29415889 | J:315620
 
First Author: Barnette DN
Year: 2018
Journal: JCI Insight
Title: iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.
Volume: 3
Issue: 3
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Publication
30165303 | J:313195
 
First Author: Chenxu G
Year: 2018
Journal: Redox Biol
Title: iRhom2 loss alleviates renal injury in long-term PM2.5-exposed mice by suppression of inflammation and oxidative stress.
Volume: 19
Pages: 147-157
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Publication
27393687 | J:319206
First Author: Yang L
Year: 2016
Journal: Arch Dermatol Res
Title: iRhom2 (Uncv) mutation blocks bulge stem cells assuming the fate of hair follicle.
Volume: 308
Issue: 7
Pages: 503-10
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21439629 | J:173119
First Author: Zettl M
Year: 2011
Journal: Cell
Title: Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling.
Volume: 145
Issue: 1
Pages: 79-91
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23969955 | J:203951
First Author: Christova Y
Year: 2013
Journal: EMBO Rep
Title: Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation.
Volume: 14
Issue: 10
Pages: 884-90
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Publication
29045841 | J:254204
First Author: Cavadas M
Year: 2017
Journal: Cell Rep
Title: Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE.
Volume: 21
Issue: 3
Pages: 745-757
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Publication
34937930 | J:320534
First Author: Kubo S
Year: 2022
Journal: Nat Immunol
Title: Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease.
Volume: 23
Issue: 1
Pages: 75-85
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Publication
27428826 | J:259147
First Author: Luo WW
Year: 2016
Journal: Nat Immunol
Title: iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.
Volume: 17
Issue: 9
Pages: 1057-66
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Publication
32646486 | J:291556
First Author: Hosur V
Year: 2020
Journal: Genome Biol
Title: Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation.
Volume: 21
Issue: 1
Pages: 168
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Publication
33576385 | J:341296
First Author: Hannemann C
Year: 2022
Journal: Cardiovasc Res
Title: Deficiency of inactive rhomboid protein 2 (iRhom2) attenuates diet-induced hyperlipidaemia and early atherogenesis.
Volume: 118
Issue: 1
Pages: 156-168
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Publication
33957124 | J:306272
   
First Author: Lora J
Year: 2021
Journal: J Biol Chem
Title: Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype.
Pages: 100733
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Publication
32103528 | J:304951
First Author: Tang B
Year: 2020
Journal: FASEB J
Title: Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.
Volume: 34
Issue: 4
Pages: 4956-4969
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Publication
28965953 | J:305773
First Author: Ge CX
Year: 2017
Journal: Biochem Biophys Res Commun
Title: iRhom2 deficiency relieves TNF-α associated hepatic dyslipidemia in long-term PM2.5-exposed mice.
Volume: 493
Issue: 4
Pages: 1402-1409
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Publication
29369823 | J:261790
First Author: Qing X
Year: 2018
Journal: J Clin Invest
Title: iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.
Volume: 128
Issue: 4
Pages: 1397-1412
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Publication
29897333 | J:264179
   
First Author: Oikonomidi I
Year: 2018
Journal: Elife
Title: iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.
Volume: 7
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Publication
29897336 | J:264397
   
First Author: Künzel U
Year: 2018
Journal: Elife
Title: FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.
Volume: 7
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Publication
28432785 | J:259889
   
First Author: Grieve AG
Year: 2017
Journal: Elife
Title: Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling.
Volume: 6
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Publication
37282854 | J:338016
 
First Author: Rabinowitsch AI
Year: 2023
Journal: J Cell Sci
Title: Analysis of the function of ADAM17 in iRhom2 curly-bare and tylosis with esophageal cancer mutant mice.
Volume: 136
Issue: 13
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Publication
27601030 | J:247030
First Author: Qing X
Year: 2016
Journal: Eur J Immunol
Title: iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.
Volume: 46
Issue: 12
Pages: 2737-2748
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Publication
23801765 | J:198810
First Author: Maretzky T
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.
Volume: 110
Issue: 28
Pages: 11433-8
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Publication
33227998 | J:303061
 
First Author: Fang R
Year: 2020
Journal: Int J Mol Sci
Title: Role of iRhoms 1 and 2 in Endochondral Ossification.
Volume: 21
Issue: 22
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Publication
32060096 | J:287404
First Author: Weskamp G
Year: 2020
Journal: J Biol Chem
Title: ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).
Volume: 295
Issue: 13
Pages: 4350-4358
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Publication
22246777 | J:179654
First Author: Adrain C
Year: 2012
Journal: Science
Title: Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE.
Volume: 335
Issue: 6065
Pages: 225-8
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Publication
30022999 | J:275895
 
First Author: Hosur V
Year: 2018
Journal: Front Genet
Title: RHBDF2-Regulated Growth Factor Signaling in a Rare Human Disease, Tylosis With Esophageal Cancer: What Can We Learn From Murine Models?
Volume: 9
Pages: 233
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Publication
22550345 | J:187583
First Author: Siggs OM
Year: 2012
Journal: Blood
Title: iRhom2 is required for the secretion of mouse TNFα.
Volume: 119
Issue: 24
Pages: 5769-71
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Publication
22246778 | J:179653
First Author: McIlwain DR
Year: 2012
Journal: Science
Title: iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.
Volume: 335
Issue: 6065
Pages: 229-32
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Publication
25918388 | J:221411
First Author: Li X
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Volume: 112
Issue: 19
Pages: 6080-5
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Publication
34613632 | J:317051
First Author: Tüshaus J
Year: 2021
Journal: FASEB J
Title: The pseudoprotease iRhom1 controls ectodomain shedding of membrane proteins in the nervous system.
Volume: 35
Issue: 11
Pages: e21962
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Publication
12573256 | J:82006
First Author: Johnson KR
Year: 2003
Journal: Genomics
Title: Curly bare (cub), a new mouse mutation on chromosome 11 causing skin and hair abnormalities, and a modifier gene (mcub) on chromosome 5.
Volume: 81
Issue: 1
Pages: 6-14
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Publication
29776906 | J:265993
First Author: Haxaire C
Year: 2018
Journal: Blood
Title: Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.
Volume: 132
Issue: 10
Pages: 1064-1074
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Publication
25546423 | J:228844
First Author: Leilei Y
Year: 2014
Journal: PLoS One
Title: iRhom2 mutation leads to aberrant hair follicle differentiation in mice.
Volume: 9
Issue: 12
Pages: e115114
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
29223140 | J:280176
First Author: Lee MY
Year: 2018
Journal: Biomol Ther (Seoul)
Title: Collagen-Induced Arthritis Analysis in Rhbdf2 Knockout Mouse.
Volume: 26
Issue: 3
Pages: 298-305
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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