|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 262 for Gab1

<< First    < Previous  |  Next >    Last >>
0.065s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:3759267
Assay Type: RNA in situ
Annotation Date: 2007-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3516422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3759269
Age: embryonic day 13.75
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1004568
Assay Type: RNA in situ
Annotation Date: 2018-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6267461
Age: embryonic day 14.5
Specimen Label: Table S1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1004568
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540365
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4A Cochlea
Specimen Label: 4A Cochlea
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Apical
Specimen Label: 4D Apical
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7610066
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610081
Age: postnatal adult
Image: 5 Spiral ganglion
Note: Expression co-colocalized with Mettl13 and Nefh expression in neural call bodies of spiral ganglion.
Specimen Label: 5 Spiral ganglion
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3759267
Assay Type: RNA in situ
Annotation Date: 2007-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3759269
Age: embryonic day 13.75
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3759267
Assay Type: RNA in situ
Annotation Date: 2007-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3759269
Age: embryonic day 13.75
Image: 3C
Note: Expression is in the basal diencephalon.
Specimen Label: 3C
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3543827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Apical
Specimen Label: 4D Apical
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3543827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Middle
Specimen Label: 4D Middle
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3543827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Basal
Specimen Label: 4D Basal
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3549627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4A Cochlea
Specimen Label: 4A Cochlea
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3549627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Apical
Specimen Label: 4D Apical
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3549627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Middle
Specimen Label: 4D Middle
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3549627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Basal
Specimen Label: 4D Basal
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3533227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Apical
Specimen Label: 4D Apical
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3533227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Middle
Specimen Label: 4D Middle
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3533227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Basal
Specimen Label: 4D Basal
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7610066
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610081
Age: postnatal adult
Image: 5 Innervation
Note: Expression co-colocalized with Mettl13 and Nefh expression in nerve fibers innervating inner hair cells and outer hair cells in cochlear duct.
Specimen Label: 5 Innervation
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4A Cochlea
Specimen Label: 4A Cochlea
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Apical
Specimen Label: 4D Apical
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Middle
Specimen Label: 4D Middle
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Basal
Specimen Label: 4D Basal
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1906127
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4A Cochlea
Note: No detectable expression in inner or outer hair cells.
Specimen Label: 4A Cochlea
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1906127
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4A Cochlea
Note: No detectable expression in inner or outer hair cells.
Specimen Label: 4A Cochlea
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7610066
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7610081
Age: postnatal adult
Image: 5 Cochlear duct
Specimen Label: 5 Cochlear duct
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1004568
Assay Type: RNA in situ
Annotation Date: 2018-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6267461
Age: embryonic day 14.5
Specimen Label: Table S1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1004568
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540365
Age: embryonic day 14.5
Note: Ventricular zone expression was greater than in the cortical plate.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4C Utricle
Note: Expression in sensory epithelium. Little or no expression in nonsensory epitheium.
Specimen Label: 4C Utricle
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4B Ampulla
Note: Expression in sensory epithelium. Expression in transition cells. Little or no expression in nonsensory epitheium
Specimen Label: 4B Ampulla
Detected: true
Specimen Num: 2
•
•
•
•
•
Publication
32358519 | J:287305
First Author: Inoue K
Year: 2020
Journal: Nat Commun
Title: Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas.
Volume: 11
Issue: 1
Pages: 2150
•
•
•
•
•
Publication
25825741 | J:220534
First Author: Li X
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Gαi1 and Gαi3 regulate macrophage polarization by forming a complex containing CD14 and Gab1.
Volume: 112
Issue: 15
Pages: 4731-6
•
•
•
•
•
Publication
35483741 | J:324527
First Author: Matoba S
Year: 2022
Journal: Genes Dev
Title: Noncanonical imprinting sustains embryonic development and restrains placental overgrowth.
Volume: 36
Issue: 7-8
Pages: 483-494
•
•
•
•
•
Publication
15273746 | J:91609
First Author: Araki T
Year: 2004
Journal: Nat Med
Title: Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.
Volume: 10
Issue: 8
Pages: 849-57
•
•
•
•
•
Publication
23424281 | J:194528
First Author: Cao C
Year: 2013
Journal: PLoS Biol
Title: Impairment of TrkB-PSD-95 signaling in Angelman syndrome.
Volume: 11
Issue: 2
Pages: e1001478
•
•
•
•
•
Publication
15736129 | J:98531
First Author: Xie Y
Year: 2005
Journal: Mol Reprod Dev
Title: Six post-implantation lethal knockouts of genes for lipophilic MAPK pathway proteins are expressed in preimplantation mouse embryos and trophoblast stem cells.
Volume: 71
Issue: 1
Pages: 1-11
•
•
•
•
•
Publication
12176364 | J:230362
First Author: Berry DM
Year: 2002
Journal: Curr Biol
Title: A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling.
Volume: 12
Issue: 15
Pages: 1336-41
•
•
•
•
•
Publication
15314156 | J:92782
First Author: Higuchi T
Year: 2004
Journal: Mol Cell Biol
Title: MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.
Volume: 24
Issue: 17
Pages: 7456-68
•
•
•
•
•
Publication
26109068 | J:317558
First Author: Mongan M
Year: 2015
Journal: J Biol Chem
Title: Gene-Environment Interactions Target Mitogen-activated Protein 3 Kinase 1 (MAP3K1) Signaling in Eyelid Morphogenesis.
Volume: 290
Issue: 32
Pages: 19770-9
•
•
•
•
•
Publication
26728565 | J:233610
First Author: Peng Y
Year: 2016
Journal: Mol Psychiatry
Title: The autism-associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain.
Volume: 21
Issue: 7
Pages: 925-35
•
•
•
•
•
Publication
23452850 | J:206901
First Author: Findlay GM
Year: 2013
Journal: Cell
Title: Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate.
Volume: 152
Issue: 5
Pages: 1008-20
•
•
•
•
•
Publication
29386106 | J:270726
First Author: Shimada IS
Year: 2018
Journal: Cell Rep
Title: Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.
Volume: 22
Issue: 5
Pages: 1169-1184
•
•
•
•
•
Publication
26393505 | J:296619
First Author: Fan Y
Year: 2015
Journal: PLoS Genet
Title: Tissue-Specific Gain of RTK Signalling Uncovers Selective Cell Vulnerability during Embryogenesis.
Volume: 11
Issue: 9
Pages: e1005533
•
•
•
•
•
Publication
34193412 | J:314221
 
First Author: Wang Q
Year: 2021
Journal: Sci Adv
Title: Lacrimal gland budding requires PI3K-dependent suppression of EGF signaling.
Volume: 7
Issue: 27
•
•
•
•
•
Publication
30718289 | J:272613
 
First Author: Koutelou E
Year: 2019
Journal: Development
Title: USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta.
Volume: 146
Issue: 4
•
•
•
•
•
Publication
21862448 | J:198109
First Author: Oeschger FM
Year: 2012
Journal: Cereb Cortex
Title: Gene expression analysis of the embryonic subplate.
Volume: 22
Issue: 6
Pages: 1343-59
•
•
•
•
•
Publication
15102471 | J:114108
First Author: Papin J
Year: 2004
Journal: Curr Opin Biotechnol
Title: Bioinformatics and cellular signaling.
Volume: 15
Issue: 1
Pages: 78-81
•
•
•
•
•
Publication
19521500 | J:149737
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
•
•
•
•
•
Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
•
•
•
•
•
Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
•
•
•
•
•
Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
•
•
•
•
•
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
•
•
•
•
•
Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Pathway
R-MMU-180292 | GAB1 signalosome
•
•
•
•
•
Publication
25596749 | -
First Author: Chang CH
Year: 2015
Journal: Oncotarget
Title: Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinoma.
Volume: 6
Issue: 3
Pages: 1478-89
•
•
•
•
•
Interaction Experiment
Sachs M (2000)
Description: Essential role of Gab1 for signaling by the c-Met receptor in vivo.
•
•
•
•
•
Interaction Experiment
Holgado-Madruga M (2003)
Description: Gab1 is an integrator of cell death versus cell survival signals in oxidative stress.
•
•
•
•
•
Interaction Experiment
Yu CF (2002)
Description: ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase.
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7610068
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610080
Age: postnatal adult
Image: 5 Spiral ganglion
Note: Expression co-colocalized with Gab1 and Nefh expression in neural call bodies of spiral ganglion.
Specimen Label: 5 Spiral ganglion
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7610067
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610082
Age: postnatal adult
Image: 5 Spiral ganglion
Note: Expression co-colocalized with Gab1 and Nefh expression in neural call bodies of spiral ganglion.
Specimen Label: 5 Spiral ganglion
Detected: true
Specimen Num: 3
•
•
•
•
•
HT Experiment
E-GEOD-35778 | Genome-wide analysis of dorsal skin gene expression of control and K14-cre:Gab1fl mutant mice
Series Id: GSE35778
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Publication
11896055 | -
First Author: Yu CF
Year: 2002
Journal: J Biol Chem
Title: ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase.
Volume: 277
Issue: 22
Pages: 19382-8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7610068
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610080
Age: postnatal adult
Image: 5 Innervation
Note: Expression co-colocalized with Gab1 and Nefh expression in nerve fibers innervating inner hair cells and outer hair cells in cochlear duct.
Specimen Label: 5 Innervation
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7610067
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610082
Age: postnatal adult
Image: 5 Innervation
Note: Expression co-colocalized with Gab1 and Nefh expression in nerve fibers innervating inner hair cells and outer hair cells in cochlear duct.
Specimen Label: 5 Innervation
Detected: true
Specimen Num: 2
•
•
•
•
•
Protein Coding Gene
MGI:2443160 | Pag1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q3U1F9
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
•
•
•
•
•
Allele
Gab1<tm1Wbm> | MGI:1934204
Name: growth factor receptor bound protein 2-associated protein 1; targeted mutation 1, Walter Birchmeier
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Protein
Q3V3J9
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
•
•
•
•
•
Protein Domain
IPR046355 | Gab1-4-like
Type: Family
Description: This entry represents GRB2-associated-binding proteins 1-4 (Gab1-4) and similar proteins from animals. Proteins in this family contain one PH domain. GAB1 from humans and its orthologues dos and soc-1 from Drosophila and C. elegans [], respectively, function as adapter proteins that modulate intracellular signalling cascades triggered by activated receptor-type kinases. Gab1 from human plays a role in FGFR1 signalling, is involved in the MET/HGF-signalling pathway and functions as an important upstream regulator in EGF-mediated activation of mTORCs [, ].
•
•
•
•
•
Genotype
Genotype
Symbol: Gab1/Gab1
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Gab1/Gab1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Gab1/Gab1<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Gab1/Gab1
Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Protein
Q9QYY0
Organism: Mus musculus/domesticus
Length: 695  
Fragment?: false
•
•
•
•
•
Genotype
Genotype
Symbol: Cxcr4/Cxcr4 Gab1/Gab1
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Gab1/Gab1 Met/Met
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom