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Search results 101 to 200 out of 211 for Tacc2

0.053s
Type Details Score
GXD Expression    
Probe: MGI:3585108
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586232
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:3585108
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586232
Age: postnatal day 6
Note: Expression was widespread.
Specimen Label: CNS
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:3585108
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3586232
Age: embryonic day 16.0
Specimen Label: Embryo
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:3585108
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3586232
Age: embryonic day 16.0
Specimen Label: Embryo
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:3585108
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3586232
Age: embryonic day 16.0
Note: Expression was widespread.
Specimen Label: Embryo
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:5651
Specimen Label: GUDMAP:5651
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:5651
Specimen Label: GUDMAP:5651
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:5651
Specimen Label: GUDMAP:5651
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:5651
Specimen Label: GUDMAP:5651
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:5651
Specimen Label: GUDMAP:5651
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:5651
Specimen Label: GUDMAP:5651
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:5651
Specimen Label: GUDMAP:5651
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:5651
Specimen Label: GUDMAP:5651
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1869223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:5651
Specimen Label: GUDMAP:5651
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:5651
Specimen Label: GUDMAP:5651
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:5651
Specimen Label: GUDMAP:5651
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2853323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:5651
Specimen Label: GUDMAP:5651
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:13922
Specimen Label: GUDMAP:13922
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2860123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:13922
Specimen Label: GUDMAP:13922
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:2861323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:13922
Specimen Label: GUDMAP:13922
Specimen Num: 2
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:3008123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:13922
Specimen Label: GUDMAP:13922
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1869223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:13922
Specimen Label: GUDMAP:13922
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1899523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:13922
Note: Moderate regional expression in the signaling center
Specimen Label: GUDMAP:13922
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2870323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:13922
Specimen Label: GUDMAP:13922
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:3152723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5539349
Age: embryonic day 15.5
Image: GUDMAP:13922
Note: Expression in upper dorsal wedge-shaped patch of pelvic ganglia
Specimen Label: GUDMAP:13922
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6513180
Age: embryonic day 15.5
Note: Both sexes were examined; no reproducible differences were detected between them.
Specimen Label: Table 1
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3817723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6513180
Age: embryonic day 15.5
Note: Both sexes were examined; no reproducible differences were detected between them.
Specimen Label: Table 3
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3506331
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6513180
Age: embryonic day 15.5
Note: Both sexes were examined; no reproducible differences were detected between them.
Specimen Label: Table 3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:223134
Assay Type: RNA in situ
Annotation Date: 2023-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7549092
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:223134
Assay Type: RNA in situ
Annotation Date: 2023-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7549092
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:223134
Assay Type: RNA in situ
Annotation Date: 2023-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7549092
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
Publication
First Author: Piekorz RP
Year: 2002
Journal: EMBO J
Title: The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis.
Volume: 21
Issue: 4
Pages: 653-64
Publication
First Author: Xie Z
Year: 2007
Journal: Neuron
Title: Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.
Volume: 56
Issue: 1
Pages: 79-93
Publication
First Author: Evsikov AV
Year: 2004
Journal: Cytogenet Genome Res
Title: Systems biology of the 2-cell mouse embryo.
Volume: 105
Issue: 2-4
Pages: 240-50
Publication
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
Publication
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
Publication  
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Protein
Organism: Mus musculus/domesticus
Length: 1919  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 106  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 360  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 669  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1770  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 255  
Fragment?: false
Publication
First Author: Gergely F
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The TACC domain identifies a family of centrosomal proteins that can interact with microtubules.
Volume: 97
Issue: 26
Pages: 14352-7
Publication  
First Author: Mortuza GB
Year: 2014
Journal: Nat Commun
Title: XTACC3-XMAP215 association reveals an asymmetric interaction promoting microtubule elongation.
Volume: 5
Pages: 5072
Publication
First Author: Sato M
Year: 2007
Journal: Nature
Title: Alp7/TACC is a crucial target in Ran-GTPase-dependent spindle formation in fission yeast.
Volume: 447
Issue: 7142
Pages: 334-7
Publication
First Author: Tang NH
Year: 2015
Journal: J Cell Sci
Title: Alp7/TACC recruits kinesin-8-PP1 to the Ndc80 kinetochore protein for timely mitotic progression and chromosome movement.
Volume: 128
Issue: 2
Pages: 354-63
Protein Domain
Type: Family
Description: The TACC protein family localises to the centrosome (the spindle pole body in fungi) and mitotic spindle, and plays a crucial role in bipolar spindle assembly [, ]. Furthermore, Alp7/TACC recruits kinesin-8-PP1 to the kinetochore to regulate timely mitotic progression and chromosome movement during anaphase A [].There is only one TACC protein in the nematode Caenorhabditis elegans (TAC-1), in Drosophila melanogaster (D-TACC), in Xenopus laevis (Maskin), and in fission yeast (Alp7 also known as Mia1p); by contrast, mammals have three TACC proteins (TACC1, TACC2 and TACC3) [].
Protein Domain
Type: Domain
Description: This entry represents a C-terminal domain found in the the proteins TACC 1, 2 and 3 (TACC1-3). TACC1 is found concentrated in the centrosomes of eukaryotes which may play a conserved role in organising centrosomal microtubules. The human TACC proteins have been linked to cancer and TACC2 has been identified as a possible tumour suppressor (AZU-1) []. TACC 3 from Xenopus laevis, also known as maskin, associates XMAP215 and promotes efficient microtubule elongation during mitosis []. Maskin is also found to bind CPEB and elF-4E []. Interestingly, the functional homologue (Alp7) in Schizosaccharomyces pombe (not included in this entry) has been shown to be required for organisation of bipolar spindles [].
Protein
Organism: Mus musculus/domesticus
Length: 1149  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 774  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 630  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2879  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 555  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 558  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 829  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1020  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 910  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1146  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 696  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1033  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 426  
Fragment?: false