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Search results 201 to 217 out of 217 for Nlk

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0.019s

Type

Details

Score

Strain

MGI:5788450 | C57BL/6-Tg(Myh6/tetO-Nlk)1Jmol/J

Attribute String:

mutant strain, transgenic, coisogenic

•

Protein Domain

IPR035482 | SIS_PGI_2

Type:

Domain

Description:

Phosphoglucose isomerase (PGI) is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate []. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF) [, ]. Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.PGI is comprised of two domains; each domain is an α-β-alpha sandwich [], which correspond to a SIS (Sugar ISomerase) domain fold.

•

Protein Domain

IPR035476 | SIS_PGI_1

Type:

Domain

Description:

•

Publication

11371164 | -

First Author:	Read J
Year:	2001
Journal:	J Mol Biol
Title:	The crystal structure of human phosphoglucose isomerase at 1.6 A resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia.
Volume:	309
Issue:	2
Pages:	447-63

•

Protein

B2RXT5

Organism:	Mus musculus/domesticus
Length:	344
Fragment?:	false

•

Protein

B7ZWL9

Organism:	Mus musculus/domesticus
Length:	344
Fragment?:	false

•

Publication

6115414 | -

First Author:	Achari A
Year:	1981
Journal:	Philos Trans R Soc Lond B Biol Sci
Title:	Glucose-6-phosphate isomerase.
Volume:	293
Issue:	1063
Pages:	145-57

•

Publication

10318897 | -

First Author:	Sun YJ
Year:	1999
Journal:	Proc Natl Acad Sci U S A
Title:	The crystal structure of a multifunctional protein: phosphoglucose isomerase/autocrine motility factor/neuroleukin.
Volume:	96
Issue:	10
Pages:	5412-7

•

Publication

10770936 | -

First Author:	Chou CC
Year:	2000
Journal:	J Biol Chem
Title:	The crystal structure of phosphoglucose isomerase/autocrine motility factor/neuroleukin complexed with its carbohydrate phosphate inhibitors suggests its substrate/receptor recognition.
Volume:	275
Issue:	30
Pages:	23154-60

•

Publication

15764709 | J:159060

First Author:	Kojima H
Year:	2005
Journal:	Proc Natl Acad Sci U S A
Title:	STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation.
Volume:	102
Issue:	12
Pages:	4524-9

•

Publication

32839237 | J:301518

First Author:	Daams R
Year:	2020
Journal:	J Immunol
Title:	Deletion of Nemo-like Kinase in T Cells Reduces Single-Positive CD8⁺ Thymocyte Population.
Volume:	205
Issue:	7
Pages:	1830-1841

•

Publication

36043912 | J:330418

First Author:	Zhu X
Year:	2022
Journal:	Cancer Res
Title:	Asialoglycoprotein Receptor 1 Functions as a Tumor Suppressor in Liver Cancer via Inhibition of STAT3.
Volume:	82
Issue:	21
Pages:	3987-4000

•

Protein

A0A0U1RQ18

Organism:	Mus musculus/domesticus
Length:	191
Fragment?:	true

•

Publication

17114649 | J:187362

First Author:	Munton RP
Year:	2007
Journal:	Mol Cell Proteomics
Title:	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.
Volume:	6
Issue:	2
Pages:	283-93

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

•

Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

•

Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

•

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