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Search results 201 to 288 out of 288 for Egln1

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Type Details Score
Publication
26976644 | J:236191
First Author: Kapitsinou PP
Year: 2016
Journal: Mol Cell Biol
Title: The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice.
Volume: 36
Issue: 10
Pages: 1584-94
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Publication
34346780 | J:310431
First Author: Kassa B
Year: 2021
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Endothelial cell PHD2-HIF1α-PFKFB3 contributes to right ventricle vascular adaptation in pulmonary hypertension.
Volume: 321
Issue: 4
Pages: L675-L685
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Publication
25377876 | J:249475
First Author: Michailidou Z
Year: 2015
Journal: Diabetes
Title: Adipocyte pseudohypoxia suppresses lipolysis and facilitates benign adipose tissue expansion.
Volume: 64
Issue: 3
Pages: 733-45
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Publication
35192456 | J:321651
   
First Author: Ajouaou Y
Year: 2022
Journal: Elife
Title: The oxygen sensor prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells.
Volume: 11
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Publication
35724581 | J:328269
 
First Author: Christoph M
Year: 2022
Journal: Mol Immunol
Title: Myeloid PHD2 deficiency accelerates neointima formation via Hif-1α.
Volume: 149
Pages: 48-58
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Publication
27001147 | J:240855
 
First Author: Li L
Year: 2016
Journal: Neurobiol Dis
Title: Neuronal deficiency of HIF prolyl 4-hydroxylase 2 in mice improves ischemic stroke recovery in an HIF dependent manner.
Volume: 91
Pages: 221-35
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Publication
27795296 | J:242994
 
First Author: Guentsch A
Year: 2017
Journal: Mol Cell Biol
Title: PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages.
Volume: 37
Issue: 1
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Publication
23264599 | J:194598
First Author: Franke K
Year: 2013
Journal: Blood
Title: HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.
Volume: 121
Issue: 8
Pages: 1436-45
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Publication
22897855 | J:191820
First Author: Leite de Oliveira R
Year: 2012
Journal: Cancer Cell
Title: Gene-targeting of Phd2 improves tumor response to chemotherapy and prevents side-toxicity.
Volume: 22
Issue: 2
Pages: 263-77
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Publication
34610308 | J:326966
First Author: Angelini A
Year: 2021
Journal: Cell Rep
Title: PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes.
Volume: 37
Issue: 1
Pages: 109767
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Publication
35164902 | J:327560
   
First Author: Zheng X
Year: 2022
Journal: Elife
Title: Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes.
Volume: 11
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Publication
24145445 | J:202913
First Author: Scholz CC
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.
Volume: 110
Issue: 46
Pages: 18490-5
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Publication
18332118 | J:136034
First Author: Bishop T
Year: 2008
Journal: Mol Cell Biol
Title: Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice.
Volume: 28
Issue: 10
Pages: 3386-400
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Publication
18176562 | J:132630
First Author: Aragonés J
Year: 2008
Journal: Nat Genet
Title: Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism.
Volume: 40
Issue: 2
Pages: 170-80
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Publication
22014577 | J:177485
First Author: Adam J
Year: 2011
Journal: Cancer Cell
Title: Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.
Volume: 20
Issue: 4
Pages: 524-37
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Publication
26054543 | J:293573
First Author: Souma T
Year: 2016
Journal: J Am Soc Nephrol
Title: Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling.
Volume: 27
Issue: 2
Pages: 428-38
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Publication
32183943 | J:298376
First Author: Kullmann JA
Year: 2020
Journal: Neuron
Title: Oxygen Tension and the VHL-Hif1α Pathway Determine Onset of Neuronal Polarization and Cerebellar Germinal Zone Exit.
Volume: 106
Issue: 4
Pages: 607-623.e5
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Publication
27565342 | J:234541
First Author: Clever D
Year: 2016
Journal: Cell
Title: Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Volume: 166
Issue: 5
Pages: 1117-1131.e14
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Publication
34075041 | J:324487
First Author: Roy S
Year: 2021
Journal: Nat Commun
Title: EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells.
Volume: 12
Issue: 1
Pages: 3182
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Publication
27088801 | J:234932
First Author: Kobayashi H
Year: 2016
Journal: J Clin Invest
Title: Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin.
Volume: 126
Issue: 5
Pages: 1926-38
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Publication
32663458 | J:296608
First Author: Yoon H
Year: 2020
Journal: Cell Metab
Title: PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle.
Volume: 32
Issue: 2
Pages: 215-228.e7
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Publication
25846796 | J:221580
First Author: Wu C
Year: 2015
Journal: Genes Dev
Title: Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin.
Volume: 29
Issue: 8
Pages: 817-31
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Publication
22464323 | J:186085
First Author: Rankin EB
Year: 2012
Journal: Cell
Title: The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.
Volume: 149
Issue: 1
Pages: 63-74
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Publication
20651146 | J:162614
First Author: Minamishima YA
Year: 2010
Journal: Science
Title: Reactivation of hepatic EPO synthesis in mice after PHD loss.
Volume: 329
Issue: 5990
Pages: 407
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Publication
23649506 | J:244618
First Author: Zhu K
Year: 2013
Journal: J Bone Miner Res
Title: ATF4 promotes bone angiogenesis by increasing VEGF expression and release in the bone environment.
Volume: 28
Issue: 9
Pages: 1870-1884
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Publication
18347341 | J:133348
First Author: Ginouvès A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: PHDs overactivation during chronic hypoxia "desensitizes" HIFalpha and protects cells from necrosis.
Volume: 105
Issue: 12
Pages: 4745-50
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Publication
18040029 | J:142981
First Author: Chang EI
Year: 2007
Journal: Circulation
Title: Age decreases endothelial progenitor cell recruitment through decreases in hypoxia-inducible factor 1alpha stabilization during ischemia.
Volume: 116
Issue: 24
Pages: 2818-29
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Publication
27683416 | J:237355
First Author: Urrutia AA
Year: 2016
Journal: Blood
Title: Prolyl-4-hydroxylase 2 and 3 coregulate murine erythropoietin in brain pericytes.
Volume: 128
Issue: 21
Pages: 2550-2560
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Publication
24828078 | J:215343
First Author: Taniguchi CM
Year: 2014
Journal: Sci Transl Med
Title: PHD inhibition mitigates and protects against radiation-induced gastrointestinal toxicity via HIF2.
Volume: 6
Issue: 236
Pages: 236ra64
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Publication
36227697 | J:332218
 
First Author: Sallais J
Year: 2022
Journal: JCI Insight
Title: HIF1 inhibitor acriflavine rescues early-onset preeclampsia phenotype in mice lacking placental prolyl hydroxylase domain protein 2.
Volume: 7
Issue: 23
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Publication
35242281 | J:321522
 
First Author: Kirschner KM
Year: 2022
Journal: Oxid Med Cell Longev
Title: Adaptation of the Oxygen Sensing System during Lung Development.
Volume: 2022
Pages: 9714669
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Publication
26972007 | J:234716
First Author: Segura I
Year: 2016
Journal: Cell Rep
Title: The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A.
Volume: 14
Issue: 11
Pages: 2653-67
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Publication
24586749 | J:213829
First Author: Bard-Chapeau EA
Year: 2014
Journal: PLoS One
Title: Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.
Volume: 9
Issue: 2
Pages: e89397
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Publication
16966370 | J:114669
First Author: Takeda K
Year: 2006
Journal: Mol Cell Biol
Title: Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2.
Volume: 26
Issue: 22
Pages: 8336-46
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Publication
21270129 | J:170943
First Author: Hölscher M
Year: 2011
Journal: J Biol Chem
Title: Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury.
Volume: 286
Issue: 13
Pages: 11185-94
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Publication
28847650 | J:320427
First Author: Kobayashi H
Year: 2017
Journal: Kidney Int
Title: Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development.
Volume: 92
Issue: 6
Pages: 1370-1383
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Publication
23676498 | J:201437
First Author: Nagashima T
Year: 2013
Journal: J Clin Invest
Title: BMPR2 is required for postimplantation uterine function and pregnancy maintenance.
Volume: 123
Issue: 6
Pages: 2539-50
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Publication
20185832 | J:162597
First Author: Hyvärinen J
Year: 2010
Journal: J Biol Chem
Title: Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.
Volume: 285
Issue: 18
Pages: 13646-57
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Publication
19591821 | J:152419
First Author: Mugford JW
Year: 2009
Journal: Dev Biol
Title: High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population.
Volume: 333
Issue: 2
Pages: 312-23
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Publication
35247391 | J:323229
First Author: Rosendahl AH
Year: 2022
Journal: J Biol Chem
Title: Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.
Volume: 298
Issue: 4
Pages: 101787
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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DO Term
DOID:0080338 | familial erythrocytosis 3
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Allele
Egln1<tm1.1Kael> | MGI:3793288
Name: egl-9 family hypoxia-inducible factor 1; targeted mutation 1.1, William G Kaelin
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:3848051 | B6.129S6(FVB)-Egln1<tm1.1Kael>/J
Attribute String: congenic, targeted mutation
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Genotype
Genotype
Symbol: Egln1/Egln1
Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Allele
Egln1<tm1.1Fsl> | MGI:5521374
 
Name: egl-9 family hypoxia-inducible factor 1; targeted mutation 1.1, Frank Lee
Allele Type: Targeted
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Strain
MGI:5525922 | B6.Cg-Egln1<tm1.1Fsl> Hif1a<tm3.1Rsjo>
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:5521333 | C57BL/6-Egln1<tm1.1Fsl>/J
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:5522699 | C57BL/6-Egln1<tm1.1Fsl>
Attribute String: targeted mutation, mutant strain, coisogenic
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Genotype
Genotype
Symbol: Egln1/Egln1
Background: C57BL/6-Egln1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Egln1/Egln1<+>
Background: C57BL/6-Egln1
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Egln1/Egln1<+> Hif1a/Hif1a<+>
Background: B6.Cg-Egln1 Hif1a
Zygosity: cx
Has Mutant Allele: true
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Publication
21746877 | J:175074
First Author: Sengupta T
Year: 2011
Journal: Mol Cell Biol
Title: Hypoxia-inducible factor 1 is activated by dysregulated cyclin E during mammary epithelial morphogenesis.
Volume: 31
Issue: 18
Pages: 3885-95
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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