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Search results 101 to 192 out of 192 for Pfn2

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0.024s
Type Details Score
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_22
Specimen Label: euxassay_002518_22
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_23
Specimen Label: euxassay_002518_23
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1715823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_11
Specimen Label: euxassay_002518_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1715823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_12
Specimen Label: euxassay_002518_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1715823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_13
Specimen Label: euxassay_002518_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_07
Specimen Label: euxassay_002518_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_08
Specimen Label: euxassay_002518_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_10
Specimen Label: euxassay_002518_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_11
Specimen Label: euxassay_002518_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_12
Specimen Label: euxassay_002518_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_13
Specimen Label: euxassay_002518_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_14
Specimen Label: euxassay_002518_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_15
Specimen Label: euxassay_002518_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_16
Specimen Label: euxassay_002518_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_18
Specimen Label: euxassay_002518_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_02
Specimen Label: euxassay_002518_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_03
Specimen Label: euxassay_002518_03
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_04
Specimen Label: euxassay_002518_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_05
Specimen Label: euxassay_002518_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_06
Specimen Label: euxassay_002518_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_07
Specimen Label: euxassay_002518_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_08
Specimen Label: euxassay_002518_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_09
Specimen Label: euxassay_002518_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_10
Specimen Label: euxassay_002518_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_11
Specimen Label: euxassay_002518_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_12
Specimen Label: euxassay_002518_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_13
Specimen Label: euxassay_002518_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_14
Specimen Label: euxassay_002518_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_15
Specimen Label: euxassay_002518_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_16
Specimen Label: euxassay_002518_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_17
Specimen Label: euxassay_002518_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_18
Specimen Label: euxassay_002518_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_19
Specimen Label: euxassay_002518_19
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_20
Specimen Label: euxassay_002518_20
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_21
Specimen Label: euxassay_002518_21
Detected: true
Specimen Num: 21
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_22
Specimen Label: euxassay_002518_22
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:1054469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827168
Age: embryonic day 14.5
Image: euxassay_002518_23
Specimen Label: euxassay_002518_23
Detected: true
Specimen Num: 23
Publication    
First Author: Di Nardo A
Year: 2000
Journal: GenBank Submission
Title: Mus musculus mRNA for profilin II (pfn2 gene)
Pages: AJ272203
Publication
First Author: Mouneimne G
Year: 2012
Journal: Cancer Cell
Title: Differential remodeling of actin cytoskeleton architecture by profilin isoforms leads to distinct effects on cell migration and invasion.
Volume: 22
Issue: 5
Pages: 615-30
Publication
First Author: Widada JS
Year: 1989
Journal: Nucleic Acids Res
Title: Total coding sequence of profilin cDNA from Mus musculus macrophage.
Volume: 17
Issue: 7
Pages: 2855
Publication
First Author: Waites CL
Year: 2011
Journal: J Neurosci
Title: Piccolo regulates the dynamic assembly of presynaptic F-actin.
Volume: 31
Issue: 40
Pages: 14250-63
Publication
First Author: Bowerman M
Year: 2009
Journal: Mol Cell Neurosci
Title: SMN, profilin IIa and plastin 3: a link between the deregulation of actin dynamics and SMA pathogenesis.
Volume: 42
Issue: 1
Pages: 66-74
Publication
First Author: Witke W
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Profilin I is essential for cell survival and cell division in early mouse development.
Volume: 98
Issue: 7
Pages: 3832-6
Publication
First Author: Ni T
Year: 2020
Journal: Sci Adv
Title: Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.
Volume: 6
Issue: 5
Pages: eaax8286
Publication
First Author: Wang X
Year: 1999
Journal: J Cell Biol
Title: Aczonin, a 550-kD putative scaffolding protein of presynaptic active zones, shares homology regions with Rim and Bassoon and binds profilin.
Volume: 147
Issue: 1
Pages: 151-62
Publication
First Author: Lederer M
Year: 2005
Journal: J Cell Sci
Title: Profilin regulates the activity of p42POP, a novel Myb-related transcription factor.
Volume: 118
Issue: Pt 2
Pages: 331-41
Publication
First Author: Nölle A
Year: 2011
Journal: Hum Mol Genet
Title: The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin.
Volume: 20
Issue: 24
Pages: 4865-78
Publication
First Author: Michaelsen-Preusse K
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Neuronal profilins in health and disease: Relevance for spine plasticity and Fragile X syndrome.
Volume: 113
Issue: 12
Pages: 3365-70
Publication
First Author: Miyagi Y
Year: 2002
Journal: J Neurosci
Title: Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit.
Volume: 22
Issue: 3
Pages: 803-14
Publication
First Author: Zhang Y
Year: 2014
Journal: Cell Rep
Title: H3K36 histone methyltransferase Setd2 is required for murine embryonic stem cell differentiation toward endoderm.
Volume: 8
Issue: 6
Pages: 1989-2002
Publication
First Author: Kullmann JA
Year: 2011
Journal: EMBO Rep
Title: Profilin1 is required for glial cell adhesion and radial migration of cerebellar granule neurons.
Volume: 13
Issue: 1
Pages: 75-82
Publication
First Author: Oishi H
Year: 2005
Journal: Arthritis Rheum
Title: Accelerating effect of an MRL gene locus on the severity and onset of arthropathy in DBA/1 mice.
Volume: 52
Issue: 3
Pages: 959-66
Publication
First Author: Gareus R
Year: 2006
Journal: J Biol Chem
Title: Mouse profilin 2 regulates endocytosis and competes with SH3 ligand binding to dynamin 1.
Volume: 281
Issue: 5
Pages: 2803-11
Publication
First Author: Lin Q
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life.
Volume: 114
Issue: 34
Pages: 9188-9193
Publication
First Author: Lambrechts A
Year: 2000
Journal: J Biol Chem
Title: cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and SH3 domains.
Volume: 275
Issue: 46
Pages: 36143-51
Publication  
First Author: Di Domenico M
Year: 2021
Journal: Cells
Title: Specificity and Redundancy of Profilin 1 and 2 Function in Brain Development and Neuronal Structure.
Volume: 10
Issue: 9
Publication  
First Author: Huang R
Year: 2020
Journal: J Cell Biol
Title: NCAM regulates temporal specification of neural progenitor cells via profilin2 during corticogenesis.
Volume: 219
Issue: 1
Publication
First Author: Vasilopoulou E
Year: 2016
Journal: Kidney Int
Title: Loss of endogenous thymosin β4 accelerates glomerular disease.
Volume: 90
Issue: 5
Pages: 1056-1070
Publication
First Author: Osmundsen H
Year: 2007
Journal: Arch Oral Biol
Title: Changes in gene-expression during development of the murine molar tooth germ.
Volume: 52
Issue: 9
Pages: 803-13
Publication
First Author: Morris DJ
Year: 1993
Journal: Genomics
Title: Somatic cell hybrid mapping on mouse chromosome 11 (MMU11): assignment of markers relative to two breakpoints in band D.
Volume: 15
Issue: 2
Pages: 323-31
Publication
First Author: Schilling K
Year: 2009
Journal: Cerebellum
Title: The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex.
Volume: 8
Issue: 4
Pages: 477-89
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Figley MD
Year: 2014
Journal: J Neurosci
Title: Profilin 1 associates with stress granules and ALS-linked mutations alter stress granule dynamics.
Volume: 34
Issue: 24
Pages: 8083-97
Protein Domain
Type: Family
Description: Profilins (PFNs) are a group of small eukaryotic proteins that bind to monomeric actin (G-actin) in a 1:1 ratio thus preventing the polymerisation of actin into filaments (F-actin). They can also in certain circumstance promote actin polymerisation. Profilins also bind to polyphosphoinositides such as PIP2 []. Other ligands include members of the Ena/VASP and formin families []. Overall sequence similarity among profilin from organisms which belong to different phyla (ranging from fungi to mammals) is low, but the N-terminal region is relatively well conserved. The N-terminal region is thought to be involved in actin binding. Four Profilins have been identified in mammals, PFN1-4. PFN1 and PFN2 differentially regulate membrane protrusion, motility, and invasion; these processes are promoted by PFN1 and suppressed by PFN2 []. This entry represents PFN1.
Publication
First Author: Yu X
Year: 2022
Journal: EMBO J
Title: Cryo-EM structures of perforin-2 in isolation and assembled on a membrane suggest a mechanism for pore formation.
Volume: 41
Issue: 23
Pages: e111857
Protein
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 55  
Fragment?: false