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Search results 1 to 97 out of 97 for Myo18b

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
84700 | MYO18B
Type: gene
Organism: human
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Gene
458721 | MYO18B
Type: gene
Organism: chimpanzee
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Gene
540437 | MYO18B
Type: gene
Organism: cattle
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Gene
416905 | MYO18B
Type: gene
Organism: chicken
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Gene
714823 | MYO18B
Type: gene
Organism: macaque, rhesus
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Gene
100496668 | myo18b
Type: gene
Organism: frog, western clawed
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Gene
304551 | Myo18b
Type: gene
Organism: rat
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Gene
486328 | MYO18B
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1921626 | Myo18b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR028561 | MYO18B
Type: Family
Description: Unconventional myosin-XVIII A/B (MYO18A/B) belongs to class XIII myosin that contains two large domains of unknown function at the N and C-termini []. MYO18B appears to be expressed mainly in human cardiac and skeletal muscles and is involved in the regulation of muscle specific genes []. Its inactivation is involved in lung cancer progression [].Myosin constitutes a large superfamily of actin-dependent molecular motors. Myosin binds to actins and moves along actin filaments by using the energy from ATP hydrolysis. Myosin is involved in muscular contraction, cytokinesis, membrane trafficking and signal transduction [, ]. Myosins are typically composed of three functional domains:Motor head domain whose core sequence is highly conserved in all the myosin classes. This domain binds to actin and uses ATP hydrolysis to generate force to move along actin filaments. Neck domain composed of a long helix of variable length depending on the number of IQ motifs (has a consensus sequence of IQXXXRGXXXR) []. This domain acts as a linker and as a lever arm. The neck domain also serves as a binding site for moysin light chains, which are calmodulin-like proteins that have regulatory functions. Tail domain is the most diverse domain and vary in length and in sequence. Many myosin tails form coiled-coil structure that allow the molecules to dimerise and produce two-headed molecules. This domain mediates interaction with cargo molecules and/or other myosin subunits.
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Publication
12547197 | J:83690
First Author: Salamon M
Year: 2003
Journal: J Mol Biol
Title: Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation.
Volume: 326
Issue: 1
Pages: 137-49
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Protein
B7ZNF7
Organism: Mus musculus/domesticus
Length: 1357  
Fragment?: true
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Gene
105372963 | MYO18B-AS1
Type: gene
Organism: human
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Publication
18761673 | J:142442
First Author: Ajima R
Year: 2008
Journal: Genes Cells
Title: Deficiency of Myo18B in mice results in embryonic lethality with cardiac myofibrillar aberrations.
Volume: 13
Issue: 10
Pages: 987-99
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Publication
12209013 | -
First Author: Nishioka M
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer.
Volume: 99
Issue: 19
Pages: 12269-74
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Protein
Q9D4I1
Organism: Mus musculus/domesticus
Length: 745  
Fragment?: false
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Protein
E9PV66
Organism: Mus musculus/domesticus
Length: 2605  
Fragment?: false
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Publication
1558751 | -
First Author: Cheney RE
Year: 1992
Journal: Curr Opin Cell Biol
Title: Unconventional myosins.
Volume: 4
Issue: 1
Pages: 27-35
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Publication
8689571 | -
 
First Author: Mooseker MS
Year: 1995
Journal: Annu Rev Cell Dev Biol
Title: Unconventional myosins.
Volume: 11
Pages: 633-75
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Publication
10722873 | J:61347
First Author: Sellers JR
Year: 2000
Journal: Biochim Biophys Acta
Title: Myosins: a diverse superfamily.
Volume: 1496
Issue: 1
Pages: 3-22
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Protein Coding Gene
MGP_CAROLIEiJ_G0027569 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029910 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029876 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029814 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029887 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029607 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1921626 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030340 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029015 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029574 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029724 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029681 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029712 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030381 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028729 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029091 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024151 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028567 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:2664318
Assay Type: Northern blot
Annotation Date: 2003-07-02
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2664325
Age: postnatal
Specimen Label: testis
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2664318
Assay Type: Northern blot
Annotation Date: 2003-07-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2664325
Age: postnatal
Specimen Label: kidney
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2664318
Assay Type: Northern blot
Annotation Date: 2003-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2664325
Age: postnatal
Specimen Label: skeletal muscle
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2664318
Assay Type: Northern blot
Annotation Date: 2003-07-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2664325
Age: postnatal
Specimen Label: liver
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2664318
Assay Type: Northern blot
Annotation Date: 2003-07-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2664325
Age: postnatal
Specimen Label: lung
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2664318
Assay Type: Northern blot
Annotation Date: 2003-07-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2664325
Age: postnatal
Specimen Label: spleen
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:2664318
Assay Type: Northern blot
Annotation Date: 2003-07-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2664325
Age: postnatal
Specimen Label: brain
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:2664318
Assay Type: Northern blot
Annotation Date: 2003-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2664325
Age: postnatal
Specimen Label: heart
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:2664312
Assay Type: RT-PCR
Annotation Date: 2003-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3567028
Stage: TS28
Assay Id: MGI:2664327
Age: postnatal adult
Specimen Label: pectoralis
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2664312
Assay Type: RT-PCR
Annotation Date: 2003-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770128
Stage: TS28
Assay Id: MGI:2664327
Age: postnatal adult
Specimen Label: diaphragm
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2664312
Assay Type: RT-PCR
Annotation Date: 2003-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3537528
Stage: TS28
Assay Id: MGI:2664327
Age: postnatal adult
Specimen Label: gastrocnemius
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2664312
Assay Type: RT-PCR
Annotation Date: 2003-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Stage: TS28
Assay Id: MGI:2664327
Age: postnatal adult
Specimen Label: soleus
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2664312
Assay Type: RT-PCR
Annotation Date: 2003-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3586728
Stage: TS28
Assay Id: MGI:2664327
Age: postnatal adult
Specimen Label: tibialis
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2664312
Assay Type: RT-PCR
Annotation Date: 2003-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268828
Stage: TS28
Assay Id: MGI:2664327
Age: postnatal adult
Specimen Label: heart
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:2664312
Assay Type: RT-PCR
Annotation Date: 2003-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:2664327
Age: postnatal adult
Specimen Label: total adult
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
       
Probe: MGI:2664312
Assay Type: RT-PCR
Annotation Date: 2003-07-02
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603916
Stage: TS16
Assay Id: MGI:2664345
Age: embryonic day 10.0-12.0
Specimen Label: E10-12 d
Specimen Num: 1
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GXD Expression
GXD Expression
       
Probe: MGI:2664312
Assay Type: RT-PCR
Annotation Date: 2003-07-02
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:2664345
Age: embryonic day 10.0-12.0
Specimen Label: E10-12 d
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2664312
Assay Type: RT-PCR
Annotation Date: 2003-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:2664345
Age: embryonic day 16.5
Specimen Label: E16.5 d
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2664312
Assay Type: RT-PCR
Annotation Date: 2003-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:2664345
Age: postnatal adult
Specimen Label: Ad
Detected: true
Specimen Num: 3
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Publication
32212159 | J:296898
First Author: Tonelli Gombalová Z
Year: 2020
Journal: J Comp Neurol
Title: Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.
Volume: 528
Issue: 15
Pages: 2523-2550
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Publication
22282597 | J:315877
First Author: Tripathi P
Year: 2012
Journal: J Am Soc Nephrol
Title: Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction.
Volume: 23
Issue: 4
Pages: 618-28
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Publication
36877136 | J:336298
   
First Author: Taliani V
Year: 2023
Journal: Elife
Title: The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart.
Volume: 12
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Publication
37995181 | J:344238
First Author: Zheng Y
Year: 2023
Journal: Cell Rep
Title: Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities.
Volume: 42
Issue: 12
Pages: 113496
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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DO Term
DOID:0080592 | Klippel-Feil syndrome 4
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Publication
10733906 | J:61473
First Author: Furusawa T
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Isolation of a novel PDZ-containing myosin from hematopoietic supportive bone marrow stromal cell lines.
Volume: 270
Issue: 1
Pages: 67-75
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Publication
12761286 | -
First Author: Mori K
Year: 2003
Journal: J Biochem
Title: Genome structure and differential expression of two isoforms of a novel PDZ-containing myosin (MysPDZ) (Myo18A).
Volume: 133
Issue: 4
Pages: 405-13
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Publication
15582604 | -
First Author: Mori K
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Subcellular localization and dynamics of MysPDZ (Myo18A) in live mammalian cells.
Volume: 326
Issue: 2
Pages: 491-8
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Publication
21498886 | -
First Author: Guzik-Lendrum S
Year: 2011
Journal: J Biol Chem
Title: Drosophila melanogaster myosin-18 represents a highly divergent motor with actin tethering properties.
Volume: 286
Issue: 24
Pages: 21755-66
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Protein Domain
IPR036064 | MYSc_Myo18
Type: Domain
Description: Many members of myosin class XVIII contain an N-terminal PDZ domain which is commonly found in proteins establishing molecular complexes. Mammals express a second isoform, Myo18B, that lacks the PDZ domain []. They also contain a motor domain which does not exhibit ATPase activity, suggesting that these myosins function as an actin tether protein [, ]. They also have two IQ domains that probably bind light chains or related calmodulins and a C-terminal tail with two sections of coiled-coil domains, which are thought to mediate homodimerization []. Myo18A has been implicated in stromal cell differentiation []and Myo18B in tumor suppression [].This entry represents the motor domain.
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Publication
15835906 | -
First Author: Isogawa Y
Year: 2005
Journal: Biochemistry
Title: The N-terminal domain of MYO18A has an ATP-insensitive actin-binding site.
Volume: 44
Issue: 16
Pages: 6190-6
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Protein
A0A4Y5WWJ7
Organism: Mus musculus/domesticus
Length: 2409  
Fragment?: false
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Protein
E9QA74
Organism: Mus musculus/domesticus
Length: 1642  
Fragment?: false
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Protein
E9Q405
Organism: Mus musculus/domesticus
Length: 1700  
Fragment?: false
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Protein
A0A1C7ZN10
Organism: Mus musculus/domesticus
Length: 1722  
Fragment?: false
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Protein
Q9JMH9
Organism: Mus musculus/domesticus
Length: 2050  
Fragment?: false
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Protein
E9QAX2
Organism: Mus musculus/domesticus
Length: 2083  
Fragment?: false
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Protein
K3W4L0
Organism: Mus musculus/domesticus
Length: 2036  
Fragment?: false
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Protein
B2RRE2
Organism: Mus musculus/domesticus
Length: 2047  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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