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Search results 101 to 200 out of 207 for Apoa4

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Type Details Score
Publication
14974682 | J:87328
First Author: Suto J
Year: 2003
Journal: Biochem Genet
Title: Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in KK x RR F2 mice.
Volume: 41
Issue: 9-10
Pages: 325-41
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Publication
14999024 | J:88523
First Author: Rikke BA
Year: 2004
Journal: J Gerontol A Biol Sci Med Sci
Title: Quantitative trait Loci specifying the response of body temperature to dietary restriction.
Volume: 59
Issue: 2
Pages: 118-25
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Publication
18188184 | J:168191
First Author: Yadav N
Year: 2008
Journal: EMBO Rep
Title: CARM1 promotes adipocyte differentiation by coactivating PPARgamma.
Volume: 9
Issue: 2
Pages: 193-8
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Publication
12810823 | J:94547
First Author: Sehayek E
Year: 2003
Journal: J Lipid Res
Title: Loci controlling plasma non-HDL and HDL cholesterol levels in a C57BL /6J x CASA /Rk intercross.
Volume: 44
Issue: 9
Pages: 1744-50
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Publication
9832509 | J:51304
First Author: Morrisey EE
Year: 1998
Journal: Genes Dev
Title: GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo.
Volume: 12
Issue: 22
Pages: 3579-90
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Publication
17916774 | J:127711
First Author: Wang SS
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice.
Volume: 27
Issue: 12
Pages: 2671-6
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Publication
19389805 | J:151206
First Author: Babeu JP
Year: 2009
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatocyte nuclear factor 4alpha contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation.
Volume: 297
Issue: 1
Pages: G124-34
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Publication
9494081 | J:46862
 
First Author: Oesterreicher TJ
Year: 1998
Journal: Biochem J
Title: Intestinal maturation in mice lacking CCAAT/enhancer-binding protein alpha (C/EPBalpha).
Volume: 330 ( Pt 3)
Pages: 1165-71
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Publication
17222401 | J:119141
First Author: Mandel S
Year: 2007
Journal: Dev Biol
Title: Activity-dependent neuroprotective protein (ADNP) differentially interacts with chromatin to regulate genes essential for embryogenesis.
Volume: 303
Issue: 2
Pages: 814-24
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Publication
9616220 | J:48038
First Author: Mehrabian M
Year: 1998
Journal: J Clin Invest
Title: Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model.
Volume: 101
Issue: 11
Pages: 2485-96
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Publication
19968565 | J:233135
First Author: Simmonds CS
Year: 2010
Journal: J Bone Miner Res
Title: Parathyroid hormone regulates fetal-placental mineral homeostasis.
Volume: 25
Issue: 3
Pages: 594-605
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Publication
18617288 | J:138863
First Author: Hayhurst GP
Year: 2008
Journal: J Hepatol
Title: Morphogenetic competence of HNF4 alpha-deficient mouse hepatic cells.
Volume: 49
Issue: 3
Pages: 384-95
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Publication
17086191 | J:169896
First Author: Baur JA
Year: 2006
Journal: Nature
Title: Resveratrol improves health and survival of mice on a high-calorie diet.
Volume: 444
Issue: 7117
Pages: 337-42
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Publication
29684311 | J:263836
First Author: Srivillibhuthur M
Year: 2018
Journal: Dev Biol
Title: TFAM is required for maturation of the fetal and adult intestinal epithelium.
Volume: 439
Issue: 2
Pages: 92-101
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Publication
16109169 | J:103454
 
First Author: Woda JM
Year: 2005
Journal: BMC Dev Biol
Title: Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo.
Volume: 5
Pages: 17
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Publication
24929016 | J:214986
First Author: Walker EM
Year: 2014
Journal: Dev Biol
Title: GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development.
Volume: 392
Issue: 2
Pages: 283-94
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Publication
23684747 | J:315740
First Author: Prévot PP
Year: 2013
Journal: Gastroenterology
Title: Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6.
Volume: 145
Issue: 3
Pages: 668-78.e3
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Publication
25209997 | J:228779
 
First Author: Alpern D
Year: 2014
Journal: Elife
Title: TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.
Volume: 3
Pages: e03613
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Publication
16498401 | J:106993
First Author: Briançon N
Year: 2006
Journal: EMBO J
Title: In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping.
Volume: 25
Issue: 6
Pages: 1253-62
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Publication
14660441 | J:87048
First Author: Gu G
Year: 2004
Journal: Development
Title: Global expression analysis of gene regulatory pathways during endocrine pancreatic development.
Volume: 131
Issue: 1
Pages: 165-79
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Publication
10926756 | J:64018
First Author: Wang CC
Year: 2000
Journal: Dev Biol
Title: Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera.
Volume: 224
Issue: 2
Pages: 152-67
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Publication
21386911 | J:171050
First Author: Thiagarajan RD
Year: 2011
Journal: PLoS One
Title: Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.
Volume: 6
Issue: 2
Pages: e17286
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
- | J:345476
       
First Author: Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas
Year: 2023
Title: TreeGrafter-generated GO annotations
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Allele
Tg(APOA4)8022Feb | MGI:2652475
Name: transgene insertion 8022, Francisco E Baralle
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(APOA4)8021Feb | MGI:2652472
Name: transgene insertion 8021, Francisco E Baralle
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:4834200 | STOCK Tg(APOA4)8022Feb/Cnrm
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:4834199 | STOCK Tg(APOA4)8021Feb/Cnrm
Attribute String: transgenic, mutant stock
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Allele
Apoc3<tm1Unc> | MGI:1857128
Name: apolipoprotein C-III; targeted mutation 1, University of North Carolina
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tg(APOA4)8018Feb | MGI:2652473
Name: transgene insertion 8018, Francisco E Baralle
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:2164730 | B6;129S-Apoc3<tm1Unc>/J
Attribute String: targeted mutation, mutant stock
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Strain
MGI:2161708 | B6.129-Apoc3<tm1Unc>/J
Attribute String: congenic, targeted mutation
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Publication
8089130 | J:21750
First Author: Maeda N
Year: 1994
Journal: J Biol Chem
Title: Targeted disruption of the apolipoprotein C-III gene in mice results in hypotriglyceridemia and protection from postprandial hypertriglyceridemia.
Volume: 269
Issue: 38
Pages: 23610-6
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Publication
15734841 | J:105136
First Author: Duivenvoorden I
Year: 2005
Journal: Diabetes
Title: Apolipoprotein C3 deficiency results in diet-induced obesity and aggravated insulin resistance in mice.
Volume: 54
Issue: 3
Pages: 664-71
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Publication
28887372 | J:245484
First Author: Sundaram M
Year: 2017
Journal: J Lipid Res
Title: The apolipoprotein C-III (Gln38Lys) variant associated with human hypertriglyceridemia is a gain-of-function mutation.
Volume: 58
Issue: 11
Pages: 2188-2196
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Genotype
Genotype
Symbol: Apoc3/Apoc3<+>
Background: involves: 129
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apoc3/Apoc3
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apoc3/Apoc3<+>
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apoc3/Apoc3
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apoc3/Apoc3
Background: B6.129-Apoc3/J
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:4834198 | B6.Cg-Tg(APOA4)8018Feb/Cnrm
Attribute String: congenic, mutant strain, transgenic
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Publication
21666694 | J:268074
First Author: Lee JH
Year: 2011
Journal: Nat Med
Title: The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism.
Volume: 17
Issue: 7
Pages: 812-5
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HT Experiment
E-GEOD-29643 | The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism
Series Id: GSE29643
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE211980 | Apolipoprotein A-IV reduced metabolic inflammation in white adipose tissue by inhibiting IKK and JNK signaling in adipocytes
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
25941406 | J:221652
First Author: Ã…vall K
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes.
Volume: 112
Issue: 20
Pages: E2611-9
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Publication
11590213 | J:72320
First Author: Jong MC
Year: 2001
Journal: J Lipid Res
Title: Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice.
Volume: 42
Issue: 10
Pages: 1578-85
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Publication
15863838 | J:100499
First Author: Gerritsen G
Year: 2005
Journal: J Lipid Res
Title: ApoC-III deficiency prevents hyperlipidemia induced by apoE overexpression.
Volume: 46
Issue: 7
Pages: 1466-73
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Publication
11397714 | J:103190
First Author: Ostos MA
Year: 2001
Journal: Arterioscler Thromb Vasc Biol
Title: Antioxidative and antiatherosclerotic effects of human apolipoprotein A-IV in apolipoprotein E-deficient mice.
Volume: 21
Issue: 6
Pages: 1023-8
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Publication
18263930 | J:135252
First Author: Gerritsen G
Year: 2008
Journal: J Lipid Res
Title: ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency.
Volume: 49
Issue: 5
Pages: 1048-55
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Protein
P08226
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Protein
Q00623
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: false
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Protein
Q8C7G5
Organism: Mus musculus/domesticus
Length: 368  
Fragment?: false
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Protein
P06728
Organism: Mus musculus/domesticus
Length: 395  
Fragment?: false
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Protein
Q6GTX3
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Protein
Q3TX45
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Protein
G3UWN5
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: true
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Protein
Q01488
Organism: Mus musculus/domesticus
Length: 435  
Fragment?: false
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Protein
Q3UEE7
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Protein
Q3V2G1
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: false
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Protein
Q9DBN0
Organism: Mus musculus/domesticus
Length: 395  
Fragment?: false
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Protein
Q3UBS0
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Protein
Q4FK40
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Protein
G3UZM8
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: true
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Protein
A0A1B0GX15
Organism: Mus musculus/domesticus
Length: 231  
Fragment?: true
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Protein
Q58EV2
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: false
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Protein
Q3TXU4
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Publication
2063194 | -
First Author: Wilson C
Year: 1991
Journal: Science
Title: Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E.
Volume: 252
Issue: 5014
Pages: 1817-22
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Publication
15108119 | -
First Author: Fullerton SM
Year: 2004
Journal: Hum Genet
Title: The effects of scale: variation in the APOA1/C3/A4/A5 gene cluster.
Volume: 115
Issue: 1
Pages: 36-56
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Publication
15234552 | -
First Author: Saito H
Year: 2004
Journal: Prog Lipid Res
Title: Contributions of domain structure and lipid interaction to the functionality of exchangeable human apolipoproteins.
Volume: 43
Issue: 4
Pages: 350-80
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Protein Domain
IPR000074 | ApoA_E
Type: Family
Description: Exchangeable apolipoproteins (apoA, apoC and apoE) have the same genomic structure and are members of a multi-gene family that probably evolved from a common ancestral gene. This entry includes the ApoA1, ApoA4, Apo5 and ApoE proteins. ApoA1, ApoA4 and Apo5 are part of the APOA1/C3/A4/A5 gene cluster on chromosome 11 []. Apolipoproteins function in lipid transport as structural components of lipoprotein particles, cofactors for enzymes and ligands for cell-surface receptors. In particular, apoA1 is the major protein component of high-density lipoproteins; apoA4 is thought to act primarily in intestinal lipid absorption; and apoE is a blood plasma protein that mediates the transport and uptake of cholesterol and lipid by way of its high affinity interaction with different cellular receptors, including the low-density lipoprotein (LDL) receptor. Recent findings with apoA1 and apoE suggest that the tertiary structures of these two members of the human exchangeable apolipoprotein gene family are related []. The three-dimensional structure of the LDL receptor-binding domain of apoE indicates that the protein forms an unusually elongated four-helix bundle that may be stabilised by a tightly packed hydrophobic core that includes leucine zipper-type interactions and by numerous salt bridges on the mostly charged surface. Basic amino acids important for LDL receptor binding are clustered into a surface patch on one long helix [].
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Publication
26160324 | J:258766
First Author: Li H
Year: 2015
Journal: Cardiovasc Res
Title: Aggravated restenosis and atherogenesis in ApoCIII transgenic mice but lack of protection in ApoCIII knockouts: the effect of authentic triglyceride-rich lipoproteins with and without ApoCIII.
Volume: 107
Issue: 4
Pages: 579-89
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Publication
28825717 | J:254382
First Author: Khetarpal SA
Year: 2017
Journal: Nat Med
Title: A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels.
Volume: 23
Issue: 9
Pages: 1086-1094
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Publication
23542898 | J:213303
First Author: Graham MJ
Year: 2013
Journal: Circ Res
Title: Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans.
Volume: 112
Issue: 11
Pages: 1479-90
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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