Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3763044 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-12-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1633317 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:3763071 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
2 E10.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6164309 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-05 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611717 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:6164310 |
Age: |
embryonic day 10.5 |
Image: |
1a/a' |
|
Specimen Label: |
1a/a' |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6323628 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-07-18 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1605211 |
Pattern: |
Not Specified |
Stage: |
TS11 |
Assay Id: |
MGI:6323630 |
Age: |
embryonic day 7.5 |
Image: |
5A/B/C/D |
Note: |
Most intense. |
Specimen Label: |
5A/B/C/D |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3590528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693174 |
Age: |
postnatal adult |
Image: |
JAX_1799256 |
|
Specimen Label: |
JAX_1799256 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1752528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693174 |
Age: |
postnatal adult |
Image: |
JAX_1799274 |
|
Specimen Label: |
JAX_1799274 |
Detected: |
true |
Specimen Num: |
31 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3763044 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-12-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1706619 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:3763071 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
2 E11.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3763044 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-12-05 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3557728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3763071 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2 adult |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1702128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693174 |
Age: |
postnatal adult |
Image: |
JAX_1799273 |
|
Specimen Label: |
JAX_1799273 |
Detected: |
true |
Specimen Num: |
30 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3763044 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-12-05 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3763071 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2 adult |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693174 |
Age: |
postnatal adult |
Image: |
JAX_1799257 |
|
Specimen Label: |
JAX_1799257 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3763044 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-12-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3273022 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:3763071 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
2 E14.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1757728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693174 |
Age: |
postnatal adult |
Image: |
JAX_1799267 |
|
Specimen Label: |
JAX_1799267 |
Detected: |
true |
Specimen Num: |
24 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3763044 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-12-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1618417 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:3763071 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
2 E10.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3763044 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-12-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1618419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:3763071 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
2 E11.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6323628 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-07-18 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1605111 |
Pattern: |
Regionally restricted |
Stage: |
TS11 |
Assay Id: |
MGI:6323630 |
Age: |
embryonic day 7.5 |
Image: |
5A/B/C/D |
Note: |
Most intense in the nascent mesoderm located in the distal region of the primitive streak. |
Specimen Label: |
5A/B/C/D |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2991528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693174 |
Age: |
postnatal adult |
Image: |
JAX_1799253 |
|
Specimen Label: |
JAX_1799253 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693174 |
Age: |
postnatal adult |
Image: |
JAX_1799279 |
|
Specimen Label: |
JAX_1799279 |
Detected: |
true |
Specimen Num: |
36 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693174 |
Age: |
postnatal adult |
Image: |
JAX_1799255 |
|
Specimen Label: |
JAX_1799255 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3763044 |
Assay Type: |
RNA in situ |
Annotation Date: |
2011-09-16 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1729526 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:5285690 |
Age: |
embryonic day 19.0 |
Image: |
6E,F |
Note: |
Highest level of expression in sensory neuroepithelium in the inferolateral wall of the utricle. |
Specimen Label: |
6E,F |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1881228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693174 |
Age: |
postnatal adult |
Image: |
JAX_1799258 |
|
Specimen Label: |
JAX_1799258 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3763044 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-12-05 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3561128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3763071 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2 adult |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6164309 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-05 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3705417 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:6164310 |
Age: |
embryonic day 10.5 |
Image: |
1a/a' |
|
Specimen Label: |
1a/a' |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6164309 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-05 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3705413 |
Pattern: |
Not Specified |
Stage: |
TS13 |
Assay Id: |
MGI:6164310 |
Age: |
embryonic day 8.5 |
Image: |
1b |
|
Specimen Label: |
1b |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6164309 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-05 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3705413 |
Pattern: |
Not Specified |
Stage: |
TS13 |
Assay Id: |
MGI:6164310 |
Age: |
embryonic day 8.5 |
Image: |
1b' |
|
Specimen Label: |
1b' |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakagawa T |
Year: |
1993 |
Journal: |
FEBS Lett |
Title: |
Identification of an isoform with an extremely large Cys-rich region of PC6, a Kex2-like processing endoprotease. |
Volume: |
327 |
Issue: |
2 |
Pages: |
165-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakagawa T |
Year: |
1993 |
Journal: |
J Biochem |
Title: |
Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4. |
Volume: |
113 |
Issue: |
2 |
Pages: |
132-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wong BS |
Year: |
2002 |
Journal: |
Mol Reprod Dev |
Title: |
Subtilisin proprotein convertase-6 expression in the mouse uterus during implantation and artificially induced decidualization. |
Volume: |
61 |
Issue: |
4 |
Pages: |
453-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shifley ET |
Year: |
2008 |
Journal: |
Biochim Biophys Acta |
Title: |
Lunatic fringe protein processing by proprotein convertases may contribute to the short protein half-life in the segmentation clock. |
Volume: |
1783 |
Issue: |
12 |
Pages: |
2384-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun X |
Year: |
2009 |
Journal: |
Mol Cancer |
Title: |
The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model. |
Volume: |
8 |
|
Pages: |
73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Al Rifai O |
Year: |
2021 |
Journal: |
Front Endocrinol (Lausanne) |
Title: |
In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23. |
Volume: |
12 |
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Pages: |
690681 |
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•
•
•
•
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Publication |
First Author: |
Rehfeld JF |
Year: |
2008 |
Journal: |
Biochem J |
Title: |
Prohormone convertases 1/3 and 2 together orchestrate the site-specific cleavages of progastrin to release gastrin-34 and gastrin-17. |
Volume: |
415 |
Issue: |
1 |
Pages: |
35-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Essalmani R |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
In vivo evidence that furin from hepatocytes inactivates PCSK9. |
Volume: |
286 |
Issue: |
6 |
Pages: |
4257-63 |
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•
•
•
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Publication |
First Author: |
Essalmani R |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
Thrombin activation of protein C requires prior processing by a liver proprotein convertase. |
Volume: |
292 |
Issue: |
25 |
Pages: |
10564-10573 |
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•
•
•
•
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Publication |
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Schaner P |
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1997 |
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J Biol Chem |
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Processing of prothyrotropin-releasing hormone by the family of prohormone convertases. |
Volume: |
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32 |
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19958-68 |
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•
•
•
•
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Publication |
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Decroly E |
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1996 |
Journal: |
J Biol Chem |
Title: |
Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines. |
Volume: |
271 |
Issue: |
48 |
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30442-50 |
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•
•
•
•
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Publication |
First Author: |
Nour N |
Year: |
2005 |
Journal: |
Mol Biol Cell |
Title: |
The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases. |
Volume: |
16 |
Issue: |
11 |
Pages: |
5215-26 |
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•
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•
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Publication |
First Author: |
Wickham L |
Year: |
2005 |
Journal: |
J Neurochem |
Title: |
Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin. |
Volume: |
92 |
Issue: |
1 |
Pages: |
93-102 |
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•
•
•
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Publication |
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Al Rifai O |
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2017 |
Journal: |
J Clin Invest |
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Proprotein convertase furin regulates osteocalcin and bone endocrine function. |
Volume: |
127 |
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11 |
Pages: |
4104-4117 |
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•
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2006 |
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J Biol Chem |
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On the processing of proghrelin to ghrelin. |
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38867-70 |
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Year: |
2015 |
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BMC Genomics |
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Variant mapping and mutation discovery in inbred mice using next-generation sequencing. |
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16 |
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J Biol Chem |
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CDMP1/GDF5 has specific processing requirements that restrict its action to joint surfaces. |
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J Biol Chem |
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Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes. |
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Dev Genet |
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Murine subtilisin-like proteinase SPC6 is expressed during embryonic implantation, somitogenesis, and skeletal formation. |
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1 |
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Proc Natl Acad Sci U S A |
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A widely expressed betaIII spectrin associated with Golgi and cytoplasmic vesicles. |
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Biochimie |
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The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions. |
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Genomics |
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Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human. |
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•
•
•
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Constam DB |
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J Cell Biol |
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Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases. |
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•
•
•
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Gut |
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Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7. |
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11 |
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1573-82 |
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•
•
•
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2010 |
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J Lipid Res |
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PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain. |
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51 |
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9 |
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2611-8 |
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•
•
•
•
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Publication |
First Author: |
Constam DB |
Year: |
1996 |
Journal: |
J Cell Biol |
Title: |
SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis. |
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1 |
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181-91 |
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•
•
•
•
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Publication |
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St Germain C |
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2005 |
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Mol Reprod Dev |
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Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development. |
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4 |
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•
•
•
•
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Publication |
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Wright A |
Year: |
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Mamm Genome |
Title: |
Mart1 is located on mouse chromosome 19 and is excluded as a candidate for ep and ru. |
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5 |
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Rousselet E |
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J Lipid Res |
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PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke. |
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Mesnard D |
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J Cell Biol |
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Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst. |
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Nature |
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Lo C |
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MGI Direct Data Submission (B2B/CvDC) |
Title: |
Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC) |
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Sundberg JP |
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2017 |
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PLoS One |
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Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. |
Volume: |
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Abonnenc M |
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2013 |
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Circ Res |
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Tamplin OJ |
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BMC Genomics |
Title: |
Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. |
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9 |
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Pages: |
511 |
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Publication |
First Author: |
University of California, Davis |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the University of California, Davis |
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Nature |
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High-throughput discovery of novel developmental phenotypes. |
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Publication |
First Author: |
The Jackson Laboratory |
Year: |
2012 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by The Jackson Laboratory |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
Journal: |
Database Download |
Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
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Koscielny G |
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2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
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Database issue |
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Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
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2014 |
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Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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The Gene Ontology Consortium |
Year: |
2014 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
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5740 |
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2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
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Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
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Title: |
Nomenclature Committee Use |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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GemPharmatech |
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2020 |
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Title: |
GemPharmatech Website. |
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First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
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2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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First Author: |
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Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
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The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Mouse Genome Informatics Scientific Curators |
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Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Mouse Genome Informatics Scientific Curators |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
|
UniProt Feature |
Begin: |
20 |
Description: |
Cleaved by PCSK5 |
Type: |
propeptide |
End: |
280 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
221 |
Description: |
Cleavage; by furin and PCSK5 |
Type: |
site |
End: |
222 |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Publication |
First Author: |
Bajikar SS |
Year: |
2017 |
Journal: |
Dev Cell |
Title: |
Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer. |
Volume: |
43 |
Issue: |
4 |
Pages: |
418-435.e13 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
67
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Cal S |
Year: |
2002 |
Journal: |
Gene |
Title: |
Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains. |
Volume: |
283 |
Issue: |
1-2 |
Pages: |
49-62 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
The PLAC (protease and lacunin) domain is a six-cysteine region of about 40 residues that is present at or near the C-terminal of various enzymes and matrix proteins, including: mammalian PACE4 (paired basic amino acid cleaving enzyme 4), mammalian PCSK5 (proprotein convertase subtilisin/kexin type 5), mammalian metalloproteinases ADAMTS-2, -3, -10, -12, -14, -16, -17, and -19, and manduca Sexta matrix protein lacunin []. The PLAC domain is often associated with other domains, such as the thrombospondin type I repeat (TSP1) (), the Kunitz proteinase inhibitor domain (), the Ig-like domain (), the WAP domain (), the subtilase domain (), or the ADAM-type metalloprotease domain (). |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu S |
Year: |
2009 |
Journal: |
Mol Endocrinol |
Title: |
Novel regulators of Fgf23 expression and mineralization in Hyp bone. |
Volume: |
23 |
Issue: |
9 |
Pages: |
1505-18 |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE14242 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
143
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
117
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
296
|
Fragment?: |
true |
|
•
•
•
•
•
|