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Search results 801 to 900 out of 1038 for Brca2

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Type Details Score
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798826
Specimen Label: JAX_1798826
Detected: true
Specimen Num: 38
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GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_07
Specimen Label: euxassay_006212_07
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_08
Specimen Label: euxassay_006212_08
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_09
Specimen Label: euxassay_006212_09
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_10
Specimen Label: euxassay_006212_10
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_11
Specimen Label: euxassay_006212_11
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_12
Specimen Label: euxassay_006212_12
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_13
Specimen Label: euxassay_006212_13
Detected: true
Specimen Num: 13
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•
GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_14
Specimen Label: euxassay_006212_14
Detected: true
Specimen Num: 14
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•
GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_15
Specimen Label: euxassay_006212_15
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_16
Specimen Label: euxassay_006212_16
Detected: true
Specimen Num: 16
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798804
Specimen Label: JAX_1798804
Detected: true
Specimen Num: 16
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798825
Specimen Label: JAX_1798825
Detected: true
Specimen Num: 37
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798813
Specimen Label: JAX_1798813
Detected: true
Specimen Num: 25
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798808
Specimen Label: JAX_1798808
Detected: true
Specimen Num: 20
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798823
Specimen Label: JAX_1798823
Detected: true
Specimen Num: 35
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798805
Specimen Label: JAX_1798805
Detected: true
Specimen Num: 17
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•
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798810
Specimen Label: JAX_1798810
Detected: true
Specimen Num: 22
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798819
Specimen Label: JAX_1798819
Detected: true
Specimen Num: 31
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798824
Specimen Label: JAX_1798824
Detected: true
Specimen Num: 36
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798803
Specimen Label: JAX_1798803
Detected: true
Specimen Num: 15
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_12
Specimen Label: euxassay_006212_12
Detected: true
Specimen Num: 12
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_13
Specimen Label: euxassay_006212_13
Detected: true
Specimen Num: 13
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_17
Specimen Label: euxassay_006212_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:974192
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823442
Age: embryonic day 14.5
Image: euxassay_006212_18
Specimen Label: euxassay_006212_18
Detected: true
Specimen Num: 18
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798830
Specimen Label: JAX_1798830
Detected: true
Specimen Num: 42
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798807
Specimen Label: JAX_1798807
Detected: true
Specimen Num: 19
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692875
Age: postnatal adult
Image: JAX_1798811
Specimen Label: JAX_1798811
Detected: true
Specimen Num: 23
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Protein
Q80VS5
Organism: Mus musculus/domesticus
Length: 365  
Fragment?: true
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Allele
Tg(Brca2*)1Sks | MGI:3830346
Name: transgene insertion 1, Shyam Sharan
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Bccip<em1Gpt> | MGI:7295846
Name: BRCA2 and CDKN1A interacting protein; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Bccip<tm1b(EUCOMM)Hmgu> | MGI:5548513
Name: BRCA2 and CDKN1A interacting protein; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Bccip<tm1e(EUCOMM)Hmgu> | MGI:4436524
Name: BRCA2 and CDKN1A interacting protein; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Bccip<tm1d(EUCOMM)Hmgu> | MGI:6489524
Name: BRCA2 and CDKN1A interacting protein; targeted mutation 1d, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Bccip<em16Gpt> | MGI:7295845
Name: BRCA2 and CDKN1A interacting protein; endonuclease-mediated mutation 16, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Bccip<tm1c(EUCOMM)Hmgu> | MGI:6489522
Name: BRCA2 and CDKN1A interacting protein; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Bccip<tm1a(EUCOMM)Hmgu> | MGI:4435867
Name: BRCA2 and CDKN1A interacting protein; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Cntrob<Gt(IST13913D8)Tigm> | MGI:5198597
 
Name: centrobin, centrosomal BRCA2 interacting protein; gene trap IST13913D8, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cntrob<em1(IMPC)Bay> | MGI:6361235
Name: centrobin, centrosomal BRCA2 interacting protein; endonuclease-mediated mutation 1, Baylor College of Medicine
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cntrob<tm1e(KOMP)Wtsi> | MGI:4364150
Name: centrobin, centrosomal BRCA2 interacting protein; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cntrob<Gt(IST13618E6)Tigm> | MGI:5177477
 
Name: centrobin, centrosomal BRCA2 interacting protein; gene trap IST13618E6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cntrob<Gt(EUCE322g01)Hmgu> | MGI:4388353
 
Name: centrobin, centrosomal BRCA2 interacting protein; gene trap EUCE322g01, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Cntrob<em1Gpt> | MGI:7297240
Name: centrobin, centrosomal BRCA2 interacting protein; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cntrob<Gt(BB0144)Wtsi> | MGI:3857964
 
Name: centrobin, centrosomal BRCA2 interacting protein; gene trap BB0144, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Cntrob<Gt(AN0733)Wtsi> | MGI:3856901
 
Name: centrobin, centrosomal BRCA2 interacting protein; gene trap AN0733, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Cntrob<tm1a(KOMP)Wtsi> | MGI:4363017
Name: centrobin, centrosomal BRCA2 interacting protein; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Publication
25016020 | J:267154
First Author: Simhadri S
Year: 2014
Journal: J Biol Chem
Title: Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice.
Volume: 289
Issue: 35
Pages: 24617-29
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Allele
Brca2<tm1Kamc> | MGI:2448890
Name: breast cancer 2, early onset; targeted mutation 1, Kimberly A McAllister
Allele Type: Targeted
Attribute String: Null/knockout
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Gene
5892 | RAD51D
Type: gene
Organism: human
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Publication
9212093 | J:41377
First Author: Brugarolas J
Year: 1997
Journal: Nat Med
Title: Double indemnity: p53, BRCA and cancer. p53 mutation partially rescues developmental arrest in Brca1 and Brca2 null mice, suggesting a role for familial breast cancer genes in DNA damage repair.
Volume: 3
Issue: 7
Pages: 721-2
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Publication
29047390 | J:317891
First Author: Droz-Rosario R
Year: 2017
Journal: Breast Cancer Res
Title: Roles of BCCIP deficiency in mammary tumorigenesis.
Volume: 19
Issue: 1
Pages: 115
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Publication
14651845 | -
First Author: Hughes-Davies L
Year: 2003
Journal: Cell
Title: EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer.
Volume: 115
Issue: 5
Pages: 523-35
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GO Term
GO:0002111 | BRCA2-BRAF35 complex
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GO Term
GO:0033593 | BRCA2-MAGE-D1 complex
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Interaction Experiment
Atanassov BS (2005)
Description: Homozygous germ line mutation in exon 27 of murine Brca2 disrupts the Fancd2-Brca2 pathway in the homologous recombination-mediated DNA interstrand cross-links repair but does not affect meiosis.
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Allele
Tg(MMTV-cre)4Mam | MGI:2176166
Name: transgene insertion 4, Lothar Hennighausen
Allele Type: Transgenic
Attribute String: Recombinase
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Genotype
Genotype
Symbol: Brca2/Brca2
Background: involves: 129P2/OlaHsd * BALB/c
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0111089 | Fanconi anemia complementation group D1
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Gene
5889 | RAD51C
Type: gene
Organism: human
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Strain
MGI:6122062 | C57BL/6N-Bccip<tm1b(EUCOMM)Hmgu>/Ieg
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:7381066 | C57BL/6NTac-Bccip<tm1a(EUCOMM)Hmgu>/Ieg
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:7388717 | C57BL/6N-Cntrob<em1(IMPC)Bay>/BayMmucd
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:6866065 | C57BL/6N-Cntrob<em1(IMPC)Bay>/Mmmh
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:4843242 | B6;129P2-Cntrob<Gt(AN0733)Wtsi>/Mmucd
Attribute String: gene trap, mutant stock
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Genotype
Genotype
Symbol: Bccip/Bccip
Background: C57BL/6N-Bccip/Ieg
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cntrob/Cntrob
Background: C57BL/6N-Cntrob/BayMmucd
Zygosity: hm
Has Mutant Allele: true
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Publication
24145349 | J:206526
First Author: Huang YY
Year: 2013
Journal: Cancer Res
Title: BCCIP suppresses tumor initiation but is required for tumor progression.
Volume: 73
Issue: 23
Pages: 7122-33
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Publication
29739757 | J:264253
First Author: Mahdi AH
Year: 2018
Journal: Cancer Res
Title: Evidence of Intertissue Differences in the DNA Damage Response and the Pro-oncogenic Role of NF-κB in Mice with Disengaged BRCA1-PALB2 Interaction.
Volume: 78
Issue: 14
Pages: 3969-3981
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Publication
17535851 | J:124008
First Author: Jeong Y
Year: 2007
Journal: J Cell Sci
Title: Characterization of NIP2/centrobin, a novel substrate of Nek2, and its potential role in microtubule stabilization.
Volume: 120
Issue: Pt 12
Pages: 2106-16
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Publication
24896180 | -
First Author: Bhatia V
Year: 2014
Journal: Nature
Title: BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2.
Volume: 511
Issue: 7509
Pages: 362-5
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Publication
17767921 | -
First Author: Min J
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Identification of Rad51 regulation by BRCA2 using Caenorhabditis elegans BRCA2 and bimolecular fluorescence complementation analysis.
Volume: 362
Issue: 4
Pages: 958-64
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Genotype
Genotype
Symbol: Bccip/Bccip<+>
Background: C57BL/6N-Bccip/Ieg
Zygosity: ht
Has Mutant Allele: true
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Allele
Brca1<tm2Cxd> | MGI:1931238
Name: breast cancer 1, early onset; targeted mutation 2, Chu-Xia Deng
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Trp53<tm1Brd> | MGI:1857590
Name: transformation related protein 53; targeted mutation 1, Allan Bradley
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Brca1/Brca1 Trp53/Trp53<+> Tg(MMTV-cre)4Mam/?
Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca1/Brca1 Tg(MMTV-cre)4Mam/? Tg(MMTV-rtTA)1Lach/? Tg(tetO-Esr1)#Paf/? Trp53/Trp53<+>
Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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DO Term
DOID:5683 | hereditary breast ovarian cancer syndrome
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Protein Domain
IPR031920 | PALB2_WD40
Type: Domain
Description: This domain is found at the C terminus of partner and localiser of BRCA2 (PALB2). It is a seven-bladed WD40-type β-propeller. It binds to the N terminus of BRCA2 [].
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Publication
29426838 | J:262752
First Author: Chiang HC
Year: 2018
Journal: Sci Rep
Title: Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development.
Volume: 8
Issue: 1
Pages: 2731
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Publication
23650262 | J:203561
First Author: Huo Y
Year: 2013
Journal: Cancer Discov
Title: Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer.
Volume: 3
Issue: 8
Pages: 894-907
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Publication
28240985 | J:244866
   
First Author: Luijsterburg MS
Year: 2017
Journal: Elife
Title: A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.
Volume: 6
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Genotype
Genotype
Symbol: Brca1/Brca1 Trp53/Trp53<+> Tg(MMTV-cre)4Mam/?
Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB
Zygosity: cn
Has Mutant Allele: true
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Publication
15611632 | -
First Author: Fei P
Year: 2005
Journal: Cell Cycle
Title: New advances in the DNA damage response network of Fanconi anemia and BRCA proteins. FAAP95 replaces BRCA2 as the true FANCB protein.
Volume: 4
Issue: 1
Pages: 80-6
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Publication
16127665 | -
First Author: Atanassov BS
Year: 2005
Journal: Genes Chromosomes Cancer
Title: Homozygous germ line mutation in exon 27 of murine Brca2 disrupts the Fancd2-Brca2 pathway in the homologous recombination-mediated DNA interstrand cross-links' repair but does not affect meiosis.
Volume: 44
Issue: 4
Pages: 429-37
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Publication
21966279 | J:176115
First Author: Lu H
Year: 2011
Journal: PLoS Genet
Title: Essential roles of BCCIP in mouse embryonic development and structural stability of chromosomes.
Volume: 7
Issue: 9
Pages: e1002291
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Publication
19117032 | J:149267
First Author: Sonn S
Year: 2009
Journal: Mol Reprod Dev
Title: Nip2/centrobin may be a substrate of Nek2 that is required for proper spindle assembly during mitosis in early mouse embryos.
Volume: 76
Issue: 6
Pages: 587-92
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Publication
10878006 | -
First Author: Ono T
Year: 2000
Journal: J Biol Chem
Title: TOK-1, a novel p21Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase.
Volume: 275
Issue: 40
Pages: 31145-54
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Publication
12912920 | -
First Author: Audhya A
Year: 2003
Journal: EMBO J
Title: Regulation of PI4,5P2 synthesis by nuclear-cytoplasmic shuttling of the Mss4 lipid kinase.
Volume: 22
Issue: 16
Pages: 4223-36
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Publication
14726710 | -
First Author: Meng X
Year: 2004
Journal: Cell Cycle
Title: Inhibition of G1 to S cell cycle progression by BCCIP beta.
Volume: 3
Issue: 3
Pages: 343-8
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Publication
17947333 | -
First Author: Lu H
Year: 2007
Journal: Nucleic Acids Res
Title: BCCIP regulates homologous recombination by distinct domains and suppresses spontaneous DNA damage.
Volume: 35
Issue: 21
Pages: 7160-70
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Protein Domain
IPR025602 | BCP1_family
Type: Family
Description: This family of proteins includes BRCA2 and CDKN1A-interacting protein (BCCIP) and Bcp1. In fungi, Bcp1 is involved in nuclear export, actin cytoskeleton organisation and vesicular transport []. Its homologue in human and mouse, BCCIP, may promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A/p21 and may be required for repair of DNA damage by homologous recombination in conjunction with BRCA2 [, , , ].
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Gene
672 | BRCA1
Type: gene
Organism: human
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Publication
22315412 | J:182010
First Author: Ezell SA
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY.
Volume: 109
Issue: 10
Pages: E613-21
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Publication
15102447 | -
First Author: Bochkarev A
Year: 2004
Journal: Curr Opin Struct Biol
Title: From RPA to BRCA2: lessons from single-stranded DNA binding by the OB-fold.
Volume: 14
Issue: 1
Pages: 36-42
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Protein
A0A0U1RNQ4
Organism: Mus musculus/domesticus
Length: 235  
Fragment?: true
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Protein
Q3USB6
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: false
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Protein
A0A0U1RQ63
Organism: Mus musculus/domesticus
Length: 246  
Fragment?: true
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Publication
21276791 | J:170858
First Author: Cappelli E
Year: 2011
Journal: Exp Cell Res
Title: Homologous recombination proteins are associated with centrosomes and are required for mitotic stability.
Volume: 317
Issue: 8
Pages: 1203-13
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Publication
19131338 | -
First Author: Garapaty S
Year: 2009
Journal: J Biol Chem
Title: Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation.
Volume: 284
Issue: 12
Pages: 7542-52
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Publication
26841866 | J:232727
First Author: Varier RA
Year: 2016
Journal: J Biol Chem
Title: Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.
Volume: 291
Issue: 14
Pages: 7313-24
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