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Search results 101 to 200 out of 360 for Adam8

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3531641
Age: embryonic day 8.5
Image: 1A,B
Specimen Label: 1A,B
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3531641
Age: embryonic day 8.5
Image: 1C
Specimen Label: 1C
Detected: false
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3531641
Age: embryonic day 8.5
Image: 1I
Specimen Label: 1I
Detected: false
Specimen Num: 6
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1815522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3531641
Age: embryonic day 14.5
Specimen Label: Not Shown
Detected: true
Specimen Num: 9
•
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•
GXD Expression
GXD Expression
   
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1774222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3531641
Age: embryonic day 14.5
Specimen Label: Not Shown
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604213
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3531641
Age: embryonic day 8.5
Image: 1A,B
Note: Expression is in the giant trophoblast layer surrounding the embryo.
Specimen Label: 1A,B
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604213
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3531641
Age: embryonic day 8.5
Image: 1C
Note: Expression is in the giant trophoblast layer surrounding the embryo.
Specimen Label: 1C
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604213
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3531641
Age: embryonic day 8.5
Image: 1G,H
Note: Expression is in cells in the chorionic plate.
Specimen Label: 1G,H
Detected: true
Specimen Num: 5
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•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2005-03-31
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1604213
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3573720
Age: embryonic day 8.5
Note: Expression is in the decidua basalis.
Specimen Label: Not Shown
Detected: true
Specimen Num: 7
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3556128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875481
Specimen Label: UC Davis_1875481
Detected: true
Specimen Num: 13
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•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1685328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875468
Specimen Label: UC Davis_1875468
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1685328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875469
Specimen Label: UC Davis_1875469
Detected: true
Specimen Num: 2
•
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1685328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875478
Specimen Label: UC Davis_1875478
Detected: true
Specimen Num: 11
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•
•
GXD Expression
GXD Expression
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Pattern: Single cells
Stage: TS22
Assay Id: MGI:3531641
Age: embryonic day 14.5
Image: 4C,D
Note: Expression is in single cells scattered throughout the liver, and along tissue surrounding the major umbilical vessels.
Specimen Label: 4C,D
Detected: true
Specimen Num: 16
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1898628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875477
Specimen Label: UC Davis_1875477
Detected: true
Specimen Num: 10
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1791622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3531641
Age: embryonic day 14.5
Image: 3A,B
Note: Expression is in cells surrounding the mandible.
Specimen Label: 3A,B
Detected: true
Specimen Num: 10
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•
GXD Expression
GXD Expression
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1842522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3531641
Age: embryonic day 14.5
Image: 4E,F,G
Note: The authors state that expression is in a nest of cells in proximity to the thymus that may correspond to a developing lymph node.
Specimen Label: 4E,F,G
Detected: true
Specimen Num: 17
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•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875484
Specimen Label: UC Davis_1875484
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875485
Specimen Label: UC Davis_1875485
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875488
Specimen Label: UC Davis_1875488
Detected: true
Specimen Num: 20
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875470
Specimen Label: UC Davis_1875470
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875471
Specimen Label: UC Davis_1875471
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875480
Specimen Label: UC Davis_1875480
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610713
Stage: TS13
Assay Id: MGI:3531641
Age: embryonic day 8.5
Image: 1I
Specimen Label: 1I
Detected: false
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1764422
Pattern: Spotted
Stage: TS22
Assay Id: MGI:3531641
Age: embryonic day 14.5
Image: 3G,H
Specimen Label: 3G,H
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1620122
Stage: TS22
Assay Id: MGI:3531641
Age: embryonic day 14.5
Image: 4H,I,J
Specimen Label: 4H,I,J
Detected: false
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1734322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3531641
Age: embryonic day 14.5
Image: 4C,D
Specimen Label: 4C,D
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875486
Specimen Label: UC Davis_1875486
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875487
Specimen Label: UC Davis_1875487
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875472
Specimen Label: UC Davis_1875472
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691107
Age: postnatal adult
Image: UC Davis_1875482
Specimen Label: UC Davis_1875482
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:3531641
Age: embryonic day 14.5
Specimen Label: Not Shown
Detected: false
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:3531641
Age: embryonic day 11.5
Image: 2A,B
Specimen Label: 2A,B
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:3531641
Age: embryonic day 14.5
Specimen Label: Not Shown
Detected: false
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3531563
Assay Type: RNA in situ
Annotation Date: 2005-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3531641
Age: embryonic day 14.5
Image: 3C,D
Note: Expression is in cells surrounding the basi-occipital bone.
Specimen Label: 3C,D
Detected: true
Specimen Num: 11
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•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2005-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3573720
Age: postnatal day 40
Image: 8D
Note: Expression is in epithelial cells.
Specimen Label: 8D
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2005-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3573720
Age: postnatal day 40
Image: 8E
Note: Expression is in epithelial cells.
Specimen Label: 8E
Detected: true
Specimen Num: 4
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Publication
8163572 | J:17855
First Author: Ballock RT
Year: 1994
Journal: J Cell Physiol
Title: Inhibition of the chondrocyte phenotype by retinoic acid involves upregulation of metalloprotease genes independent of TGF-beta.
Volume: 159
Issue: 2
Pages: 340-6
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Publication
20660068 | J:165679
First Author: Ashley RL
Year: 2010
Journal: Endocrinology
Title: Deletion of the Isg15 gene results in up-regulation of decidual cell survival genes and down-regulation of adhesion genes: implication for regulation by IL-1beta.
Volume: 151
Issue: 9
Pages: 4527-36
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Publication
21205794 | J:170542
First Author: Weber S
Year: 2011
Journal: Development
Title: The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling.
Volume: 138
Issue: 3
Pages: 495-505
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Publication
22844512 | J:189715
First Author: Chen H
Year: 2012
Journal: PLoS One
Title: Identification of novel markers of mouse fetal ovary development.
Volume: 7
Issue: 7
Pages: e41683
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Publication
28358362 | J:317911
First Author: Wang L
Year: 2017
Journal: Cell Death Dis
Title: Deletion of Stk40 impairs definitive erythropoiesis in the mouse fetal liver.
Volume: 8
Issue: 3
Pages: e2722
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Publication
16452166 | J:106064
First Author: Kobielak A
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin.
Volume: 103
Issue: 7
Pages: 2322-7
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Publication
21282332 | J:247466
First Author: Kirchhof P
Year: 2011
Journal: Circ Cardiovasc Genet
Title: PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression.
Volume: 4
Issue: 2
Pages: 123-33
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Publication
35247391 | J:323229
First Author: Rosendahl AH
Year: 2022
Journal: J Biol Chem
Title: Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.
Volume: 298
Issue: 4
Pages: 101787
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Publication
28973166 | J:253459
First Author: Inoue SI
Year: 2017
Journal: Hum Mol Genet
Title: Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice.
Volume: 26
Issue: 23
Pages: 4715-4727
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Publication
21308776 | J:233118
First Author: Abdallah BM
Year: 2011
Journal: J Bone Miner Res
Title: DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Volume: 26
Issue: 7
Pages: 1457-71
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
25629724 | J:219792
 
First Author: Schlomann U
Year: 2015
Journal: Nat Commun
Title: ADAM8 as a drug target in pancreatic cancer.
Volume: 6
Pages: 6175
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UniProt Feature
UniProt Feature
Begin: 753
Description: Cleavage; by ADAM8
Type: site
End: 754
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UniProt Feature
UniProt Feature
Begin: 1040
Description: Cleavage; by ADAM8
Type: site
End: 1041
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Allele
Adam8<em1Smoc> | MGI:7288109
Name: a disintegrin and metallopeptidase domain 8; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428107 | C57BL/6J-Adam8<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Adam8<tm1Bbl> | MGI:3527133
Name: a disintegrin and metallopeptidase domain 8; targeted mutation 1, Carl P Blobel
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Adam8<tm1.1Mdz> | MGI:4418309
Name: a disintegrin and metallopeptidase domain 8; targeted mutation 1.1, Marc D Zack
Allele Type: Targeted
Attribute String: Hypomorph
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Strain
MGI:6306297 | B6N.129P2-Adam8<tm1Bbl>/CownJ
Attribute String: targeted mutation, mutant strain, congenic
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Genotype
Genotype
Symbol: Adam8/Adam8
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Adam8/Adam8<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Strain
MGI:4418347 | DBA/1LacJ-Adam8<tm1.1Mdz>
Attribute String: targeted mutation, mutant strain, coisogenic
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Genotype
Genotype
Symbol: Adam8/Adam8
Background: DBA/1LacJ-Adam8
Zygosity: hm
Has Mutant Allele: true
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Publication
17895248 | J:128998
First Author: Moss ML
Year: 2007
Journal: J Biol Chem
Title: The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.
Volume: 282
Issue: 49
Pages: 35712-21
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Publication
29897614 | J:266031
First Author: Wang T
Year: 2018
Journal: J Leukoc Biol
Title: Trim27 confers myeloid hematopoiesis competitiveness by up-regulating myeloid master genes.
Volume: 104
Issue: 4
Pages: 799-809
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Protein
G3UXX0
Organism: Mus musculus/domesticus
Length: 275  
Fragment?: true
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Protein
A0A140LJC9
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
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Protein
A0A1L1SUC3
Organism: Mus musculus/domesticus
Length: 56  
Fragment?: true
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Publication
27196928 | -
 
First Author: Takeda S
Year: 2016
Journal: Toxins (Basel)
Title: ADAM and ADAMTS Family Proteins and Snake Venom Metalloproteinases: A Structural Overview.
Volume: 8
Issue: 5
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Publication
15922769 | -
First Author: Fox JW
Year: 2005
Journal: Toxicon
Title: Structural considerations of the snake venom metalloproteinases, key members of the M12 reprolysin family of metalloproteinases.
Volume: 45
Issue: 8
Pages: 969-85
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Protein Domain
IPR001590 | Peptidase_M12B
Type: Domain
Description: Over 70 metallopeptidase families have been identified to date. In these enzymes a divalent cation which is usually zinc, but may be cobalt, manganese or copper, activates the water molecule. The metal ion is held in place by amino acid ligands, usually three in number. In some families of co-catalytic metallopeptidases, two metal ions are observed in crystal structures ligated by five amino acids, with one amino acid ligating both metal ions. The known metal ligands are His, Glu, Asp or Lys. At least one other residue is required for catalysis, which may play an electrophillic role. Many metalloproteases contain an HEXXH motif, which has been shown in crystallographic studies to form part of the metal-binding site []. The HEXXH motif is relatively common, but can be more stringently defined for metalloproteases as 'abXHEbbHbc', where 'a' is most often valine or threonine and forms part of the S1' subsite in thermolysin and neprilysin, 'b' is an uncharged residue, and 'c' a hydrophobic residue. Proline is never found in this site, possibly because it would break the helical structure adopted by this motif in metalloproteases [].This group of metallopeptidases belong to the MEROPS peptidase family M12, subfamily M12B (adamalysin family, clan (MA(M)). The protein fold of the peptidase domain for members of this family resembles that of thermolysin, the type example for clan MA and the predicted active site residues for members of this family and thermolysin occur in the motif HEXXH [].The M12B proteinases are also referred to as adamalysins or reprolysins [, ]. The adamalysins are zinc dependent endopeptidases found in snake venom. There are some mammalian proteins such as ,and fertilin . Fertilin and closely relatedproteins appear to not have some active site residues andmay not be active enzymes.CD156 (also called ADAM8 () or MS2 human) has been implicated in extravasation of leukocytes.
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