Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603913 |
|
Stage: |
TS13 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 8.5 |
Image: |
1A,B |
|
Specimen Label: |
1A,B |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603913 |
|
Stage: |
TS13 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 8.5 |
Image: |
1C |
|
Specimen Label: |
1C |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603913 |
|
Stage: |
TS13 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 8.5 |
Image: |
1I |
|
Specimen Label: |
1I |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1815522 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Not Shown |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1774222 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Not Shown |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604213 |
Pattern: |
Regionally restricted |
Stage: |
TS13 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 8.5 |
Image: |
1A,B |
Note: |
Expression is in the giant trophoblast layer surrounding the embryo. |
Specimen Label: |
1A,B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604213 |
Pattern: |
Regionally restricted |
Stage: |
TS13 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 8.5 |
Image: |
1C |
Note: |
Expression is in the giant trophoblast layer surrounding the embryo. |
Specimen Label: |
1C |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604213 |
Pattern: |
Regionally restricted |
Stage: |
TS13 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 8.5 |
Image: |
1G,H |
Note: |
Expression is in cells in the chorionic plate. |
Specimen Label: |
1G,H |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2005-03-31 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604213 |
Pattern: |
Regionally restricted |
Stage: |
TS13 |
Assay Id: |
MGI:3573720 |
Age: |
embryonic day 8.5 |
|
Note: |
Expression is in the decidua basalis. |
Specimen Label: |
Not Shown |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3556128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875481 |
|
Specimen Label: |
UC Davis_1875481 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1685328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875468 |
|
Specimen Label: |
UC Davis_1875468 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1685328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875469 |
|
Specimen Label: |
UC Davis_1875469 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1685328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875478 |
|
Specimen Label: |
UC Davis_1875478 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
Pattern: |
Single cells |
Stage: |
TS22 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 14.5 |
Image: |
4C,D |
Note: |
Expression is in single cells scattered throughout the liver, and along tissue surrounding the major umbilical vessels. |
Specimen Label: |
4C,D |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1898628 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875477 |
|
Specimen Label: |
UC Davis_1875477 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1791622 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 14.5 |
Image: |
3A,B |
Note: |
Expression is in cells surrounding the mandible. |
Specimen Label: |
3A,B |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1842522 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 14.5 |
Image: |
4E,F,G |
Note: |
The authors state that expression is in a nest of cells in proximity to the thymus that may correspond to a developing lymph node. |
Specimen Label: |
4E,F,G |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875484 |
|
Specimen Label: |
UC Davis_1875484 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875485 |
|
Specimen Label: |
UC Davis_1875485 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1928728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875488 |
|
Specimen Label: |
UC Davis_1875488 |
Detected: |
true |
Specimen Num: |
20 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1876828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875470 |
|
Specimen Label: |
UC Davis_1875470 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1876828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875471 |
|
Specimen Label: |
UC Davis_1875471 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1876828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875480 |
|
Specimen Label: |
UC Davis_1875480 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610713 |
|
Stage: |
TS13 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 8.5 |
Image: |
1I |
|
Specimen Label: |
1I |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1764422 |
Pattern: |
Spotted |
Stage: |
TS22 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 14.5 |
Image: |
3G,H |
|
Specimen Label: |
3G,H |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1620122 |
|
Stage: |
TS22 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 14.5 |
Image: |
4H,I,J |
|
Specimen Label: |
4H,I,J |
Detected: |
false |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1734322 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 14.5 |
Image: |
4C,D |
|
Specimen Label: |
4C,D |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875486 |
|
Specimen Label: |
UC Davis_1875486 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875487 |
|
Specimen Label: |
UC Davis_1875487 |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3276428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875472 |
|
Specimen Label: |
UC Davis_1875472 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3276428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691107 |
Age: |
postnatal adult |
Image: |
UC Davis_1875482 |
|
Specimen Label: |
UC Davis_1875482 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757722 |
|
Stage: |
TS22 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Not Shown |
Detected: |
false |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1738319 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 11.5 |
Image: |
2A,B |
|
Specimen Label: |
2A,B |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1738322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Not Shown |
Detected: |
false |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3531563 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-03-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1768122 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:3531641 |
Age: |
embryonic day 14.5 |
Image: |
3C,D |
Note: |
Expression is in cells surrounding the basi-occipital bone. |
Specimen Label: |
3C,D |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2005-03-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1881228 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3573720 |
Age: |
postnatal day 40 |
Image: |
8D |
Note: |
Expression is in epithelial cells. |
Specimen Label: |
8D |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2005-03-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1881228 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3573720 |
Age: |
postnatal day 40 |
Image: |
8E |
Note: |
Expression is in epithelial cells. |
Specimen Label: |
8E |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ballock RT |
Year: |
1994 |
Journal: |
J Cell Physiol |
Title: |
Inhibition of the chondrocyte phenotype by retinoic acid involves upregulation of metalloprotease genes independent of TGF-beta. |
Volume: |
159 |
Issue: |
2 |
Pages: |
340-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ashley RL |
Year: |
2010 |
Journal: |
Endocrinology |
Title: |
Deletion of the Isg15 gene results in up-regulation of decidual cell survival genes and down-regulation of adhesion genes: implication for regulation by IL-1beta. |
Volume: |
151 |
Issue: |
9 |
Pages: |
4527-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weber S |
Year: |
2011 |
Journal: |
Development |
Title: |
The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling. |
Volume: |
138 |
Issue: |
3 |
Pages: |
495-505 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen H |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Identification of novel markers of mouse fetal ovary development. |
Volume: |
7 |
Issue: |
7 |
Pages: |
e41683 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2017 |
Journal: |
Cell Death Dis |
Title: |
Deletion of Stk40 impairs definitive erythropoiesis in the mouse fetal liver. |
Volume: |
8 |
Issue: |
3 |
Pages: |
e2722 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kobielak A |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin. |
Volume: |
103 |
Issue: |
7 |
Pages: |
2322-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kirchhof P |
Year: |
2011 |
Journal: |
Circ Cardiovasc Genet |
Title: |
PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression. |
Volume: |
4 |
Issue: |
2 |
Pages: |
123-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rosendahl AH |
Year: |
2022 |
Journal: |
J Biol Chem |
Title: |
Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia. |
Volume: |
298 |
Issue: |
4 |
Pages: |
101787 |
|
•
•
•
•
•
|
Publication |
First Author: |
Inoue SI |
Year: |
2017 |
Journal: |
Hum Mol Genet |
Title: |
Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice. |
Volume: |
26 |
Issue: |
23 |
Pages: |
4715-4727 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abdallah BM |
Year: |
2011 |
Journal: |
J Bone Miner Res |
Title: |
DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice. |
Volume: |
26 |
Issue: |
7 |
Pages: |
1457-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dickinson ME |
Year: |
2016 |
Journal: |
Nature |
Title: |
High-throughput discovery of novel developmental phenotypes. |
Volume: |
537 |
Issue: |
7621 |
Pages: |
508-514 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Koscielny G |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
Volume: |
42 |
Issue: |
Database issue |
Pages: |
D802-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Schlomann U |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
ADAM8 as a drug target in pancreatic cancer. |
Volume: |
6 |
|
Pages: |
6175 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
753 |
Description: |
Cleavage; by ADAM8 |
Type: |
site |
End: |
754 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1040 |
Description: |
Cleavage; by ADAM8 |
Type: |
site |
End: |
1041 |
|
•
•
•
•
•
|
Allele |
Name: |
a disintegrin and metallopeptidase domain 8; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Allele |
Name: |
a disintegrin and metallopeptidase domain 8; targeted mutation 1, Carl P Blobel |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
a disintegrin and metallopeptidase domain 8; targeted mutation 1.1, Marc D Zack |
Allele Type: |
Targeted |
Attribute String: |
Hypomorph |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant strain, congenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Adam8/Adam8 |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Adam8/Adam8<+> |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant strain, coisogenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Adam8/Adam8 |
Background: |
DBA/1LacJ-Adam8 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Moss ML |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events. |
Volume: |
282 |
Issue: |
49 |
Pages: |
35712-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang T |
Year: |
2018 |
Journal: |
J Leukoc Biol |
Title: |
Trim27 confers myeloid hematopoiesis competitiveness by up-regulating myeloid master genes. |
Volume: |
104 |
Issue: |
4 |
Pages: |
799-809 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
275
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
159
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
56
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Takeda S |
Year: |
2016 |
Journal: |
Toxins (Basel) |
Title: |
ADAM and ADAMTS Family Proteins and Snake Venom Metalloproteinases: A Structural Overview. |
Volume: |
8 |
Issue: |
5 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Fox JW |
Year: |
2005 |
Journal: |
Toxicon |
Title: |
Structural considerations of the snake venom metalloproteinases, key members of the M12 reprolysin family of metalloproteinases. |
Volume: |
45 |
Issue: |
8 |
Pages: |
969-85 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Over 70 metallopeptidase families have been identified to date. In these enzymes a divalent cation which is usually zinc, but may be cobalt, manganese or copper, activates the water molecule. The metal ion is held in place by amino acid ligands, usually three in number. In some families of co-catalytic metallopeptidases, two metal ions are observed in crystal structures ligated by five amino acids, with one amino acid ligating both metal ions. The known metal ligands are His, Glu, Asp or Lys. At least one other residue is required for catalysis, which may play an electrophillic role. Many metalloproteases contain an HEXXH motif, which has been shown in crystallographic studies to form part of the metal-binding site []. The HEXXH motif is relatively common, but can be more stringently defined for metalloproteases as 'abXHEbbHbc', where 'a' is most often valine or threonine and forms part of the S1' subsite in thermolysin and neprilysin, 'b' is an uncharged residue, and 'c' a hydrophobic residue. Proline is never found in this site, possibly because it would break the helical structure adopted by this motif in metalloproteases [].This group of metallopeptidases belong to the MEROPS peptidase family M12, subfamily M12B (adamalysin family, clan (MA(M)). The protein fold of the peptidase domain for members of this family resembles that of thermolysin, the type example for clan MA and the predicted active site residues for members of this family and thermolysin occur in the motif HEXXH [].The M12B proteinases are also referred to as adamalysins or reprolysins [, ]. The adamalysins are zinc dependent endopeptidases found in snake venom. There are some mammalian proteins such as ,and fertilin . Fertilin and closely relatedproteins appear to not have some active site residues andmay not be active enzymes.CD156 (also called ADAM8 () or MS2 human) has been implicated in extravasation of leukocytes. |
|
•
•
•
•
•
|