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Search results 1 to 100 out of 131 for Sik2

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
23235 | SIK2
Type: gene
Organism: human
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Gene
315649 | Sik2
Type: gene
Organism: rat
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Gene
539570 | SIK2
Type: gene
Organism: cattle
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Gene
768557 | SIK2
Type: gene
Organism: chicken
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Gene
711453 | SIK2
Type: gene
Organism: macaque, rhesus
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Gene
100125196 | sik2
Type: gene
Organism: frog, western clawed
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Gene
489410 | SIK2
Type: gene
Organism: dog, domestic
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Gene
451540 | SIK2
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2445031 | Sik2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
33688765 | J:332352
First Author: Pires NM
Year: 2021
Journal: Clin Exp Hypertens
Title: Antagonistic modulation of SIK1 and SIK2 isoforms in high blood pressure and cardiac hypertrophy triggered by high-salt intake.
Volume: 43
Issue: 5
Pages: 428-435
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Publication
12624099 | J:83587
First Author: Horike N
Year: 2003
Journal: J Biol Chem
Title: Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2.
Volume: 278
Issue: 20
Pages: 18440-7
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Publication
20819186 | J:215877
First Author: Horike N
Year: 2010
Journal: Pigment Cell Melanoma Res
Title: Downregulation of SIK2 expression promotes the melanogenic program in mice.
Volume: 23
Issue: 6
Pages: 809-19
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Publication
34732767 | J:313576
First Author: Nefla M
Year: 2021
Journal: Sci Rep
Title: Salt inducible kinases 2 and 3 are required for thymic T cell development.
Volume: 11
Issue: 1
Pages: 21550
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Publication
24898145 | J:229999
First Author: Park J
Year: 2014
Journal: Diabetes
Title: SIK2 is critical in the regulation of lipid homeostasis and adipogenesis in vivo.
Volume: 63
Issue: 11
Pages: 3659-73
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Publication
32457359 | J:288218
First Author: Park M
Year: 2020
Journal: Sci Rep
Title: Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.
Volume: 10
Issue: 1
Pages: 8676
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Publication
27920213 | J:246310
First Author: Darling NJ
Year: 2017
Journal: Biochem J
Title: Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages.
Volume: 474
Issue: 4
Pages: 521-537
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Publication
16817901 | J:121527
First Author: Katoh Y
Year: 2006
Journal: FEBS J
Title: Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade.
Volume: 273
Issue: 12
Pages: 2730-48
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Publication
36309093 | J:334306
First Author: van Gijsel-Bonnello M
Year: 2022
Journal: J Biol Chem
Title: Salt-inducible kinase 2 regulates fibrosis during bleomycin-induced lung injury.
Volume: 298
Issue: 12
Pages: 102644
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Publication
24752134 | J:215182
First Author: Popov S
Year: 2014
Journal: PLoS One
Title: Lack of salt-inducible kinase 2 (SIK2) prevents the development of cardiac hypertrophy in response to chronic high-salt intake.
Volume: 9
Issue: 4
Pages: e95771
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Publication
31409767 | J:293371
First Author: Wei T
Year: 2019
Journal: Cell Death Dis
Title: Sirtuin 3-mediated pyruvate dehydrogenase activity determines brown adipocytes phenotype under high-salt conditions.
Volume: 10
Issue: 8
Pages: 614
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Publication
28566287 | J:247040
First Author: Nakatsu Y
Year: 2017
Journal: J Biol Chem
Title: The prolyl isomerase Pin1 increases β-cell proliferation and enhances insulin secretion.
Volume: 292
Issue: 28
Pages: 11886-11895
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Publication
34160349 | J:313902
   
First Author: Tang CC
Year: 2021
Journal: Elife
Title: Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption.
Volume: 10
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Publication
24561619 | J:212985
First Author: Sakamaki J
Year: 2014
Journal: Nat Cell Biol
Title: Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.
Volume: 16
Issue: 3
Pages: 234-44
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Publication
32343771 | J:292742
 
First Author: Armouti M
Year: 2020
Journal: Endocrinology
Title: Salt-inducible Kinases Are Critical Determinants of Female Fertility.
Volume: 161
Issue: 7
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Publication
25088745 | J:242343
 
First Author: Patel K
Year: 2014
Journal: Nat Commun
Title: The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.
Volume: 5
Pages: 4535
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Publication
30030465 | J:265038
First Author: Paulo E
Year: 2018
Journal: Sci Rep
Title: Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis.
Volume: 8
Issue: 1
Pages: 11001
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Publication
21084751 | J:171868
First Author: Bricambert J
Year: 2010
Journal: J Clin Invest
Title: Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice.
Volume: 120
Issue: 12
Pages: 4316-31
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Publication
33600797 | J:304029
   
First Author: Darling NJ
Year: 2021
Journal: J Biol Chem
Title: Salt-inducible kinases are required for the IL-33-dependent secretion of cytokines and chemokines in mast cells.
Pages: 100428
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Publication
19351809 | J:149591
First Author: Muraoka M
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Involvement of SIK2/TORC2 signaling cascade in the regulation of insulin-induced PGC-1alpha and UCP-1 gene expression in brown adipocytes.
Volume: 296
Issue: 6
Pages: E1430-9
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Publication
31430259 | J:284092
First Author: Nishimori S
Year: 2019
Journal: J Clin Invest
Title: Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling.
Volume: 129
Issue: 12
Pages: 5187-5203
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Protein Coding Gene
MGP_CAROLIEiJ_G0032200 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034794 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034775 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034703 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034767 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034477 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2445031 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035287 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033799 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034449 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034608 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034549 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034689 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034592 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035308 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033504 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033912 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015068 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033339 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:7284452
Assay Type: RT-PCR
Annotation Date: 2022-06-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:7284703
Age: embryonic day 16.5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7284452
Assay Type: RT-PCR
Annotation Date: 2022-06-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:7284703
Age: embryonic day 16.5
Specimen Label: DKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4425641
Assay Type: RNA in situ
Annotation Date: 2023-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7525171
Age: embryonic day 14.5
Note: Cortical plate expression was greater than in the ventricular zone.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4425641
Assay Type: RNA in situ
Annotation Date: 2023-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7525171
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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Publication
29194435 | J:256500
First Author: Lin C
Year: 2017
Journal: PLoS One
Title: Adiposity QTL Adip20 decomposes into at least four loci when dissected using congenic strains.
Volume: 12
Issue: 12
Pages: e0188972
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Publication
25619259 | J:250540
First Author: Sanosaka M
Year: 2015
Journal: Immunology
Title: Salt-inducible kinase 3 deficiency exacerbates lipopolysaccharide-induced endotoxin shock accompanied by increased levels of pro-inflammatory molecules in mice.
Volume: 145
Issue: 2
Pages: 268-78
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Publication
36862513 | J:335756
 
First Author: Yoon SH
Year: 2023
Journal: J Clin Invest
Title: A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis.
Volume: 133
Issue: 9
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Publication
23033494 | J:190393
First Author: Clark K
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages.
Volume: 109
Issue: 42
Pages: 16986-91
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Publication
25918234 | J:236359
First Author: Kim MJ
Year: 2015
Journal: Diabetes
Title: Salt-Inducible Kinase 1 Terminates cAMP Signaling by an Evolutionarily Conserved Negative-Feedback Loop in β-Cells.
Volume: 64
Issue: 9
Pages: 3189-202
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Publication
27759007 | J:240495
 
First Author: Wein MN
Year: 2016
Journal: Nat Commun
Title: SIKs control osteocyte responses to parathyroid hormone.
Volume: 7
Pages: 13176
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Publication
30208308 | J:270632
First Author: Kuwako KI
Year: 2018
Journal: Cell Rep
Title: The LKB1-SIK Pathway Controls Dendrite Self-Avoidance in Purkinje Cells.
Volume: 24
Issue: 11
Pages: 2808-2818.e4
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Publication
29941929 | J:268740
First Author: Patra KC
Year: 2018
Journal: Nat Cell Biol
Title: Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism.
Volume: 20
Issue: 7
Pages: 811-822
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Publication
20833366 | J:164279
First Author: Trivedi CM
Year: 2010
Journal: Dev Cell
Title: Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation.
Volume: 19
Issue: 3
Pages: 450-9
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Publication
31636950 | J:330942
 
First Author: Chu Q
Year: 2019
Journal: Cell Discov
Title: STK11 is required for the normal program of ciliated cell differentiation in airways.
Volume: 5
Pages: 36
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q8CFH6
Organism: Mus musculus/domesticus
Length: 931  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 162
Description: Phosphoserine; by SIK2
Type: modified residue
End: 162
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UniProt Feature
UniProt Feature
Begin: 1
Description: Serine/threonine-protein kinase SIK2
Type: chain
End: 931
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UniProt Feature
UniProt Feature
Begin: 789
Description: Phosphoserine; by AMPK and SIK2
Type: modified residue
End: 789
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UniProt Feature
UniProt Feature
Begin: 171
Description: Phosphoserine; by AMPK, MARK2, SIK1 and SIK2
Type: modified residue
End: 171
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Interaction Experiment
Zhang ZN (2016)
Description: SIK2 regulates fasting-induced PPAR? activity and ketogenesis through p300.
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Allele
Sik2<tm1Pg> | MGI:7423839
Name: salt inducible kinase 2; targeted mutation 1, PolyGene AG
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
26983400 | -
 
First Author: Zhang ZN
Year: 2016
Journal: Sci Rep
Title: SIK2 regulates fasting-induced PPARα activity and ketogenesis through p300.
Volume: 6
Pages: 23317
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Publication
20708153 | -
First Author: Ahmed AA
Year: 2010
Journal: Cancer Cell
Title: SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer.
Volume: 18
Issue: 2
Pages: 109-21
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Publication
29211348 | -
First Author: Sonntag T
Year: 2018
Journal: FEBS J
Title: 14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs).
Volume: 285
Issue: 3
Pages: 467-480
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom