Type |
Details |
Score |
Publication |
First Author: |
Schreiner AE |
Year: |
2014 |
Journal: |
J Comp Neurol |
Title: |
Laminar and subcellular heterogeneity of GLAST and GLT-1 immunoreactivity in the developing postnatal mouse hippocampus. |
Volume: |
522 |
Issue: |
1 |
Pages: |
204-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sawangarun W |
Year: |
2018 |
Journal: |
Exp Cell Res |
Title: |
Loss of Notch1 predisposes oro-esophageal epithelium to tumorigenesis. |
Volume: |
372 |
Issue: |
2 |
Pages: |
129-140 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bai N |
Year: |
2013 |
Journal: |
Mol Brain |
Title: |
NMDA receptor subunits have different roles in NMDA-induced neurotoxicity in the retina. |
Volume: |
6 |
|
Pages: |
34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bai N |
Year: |
2013 |
Journal: |
Mol Brain |
Title: |
Dock3 interaction with a glutamate-receptor NR2D subunit protects neurons from excitotoxicity. |
Volume: |
6 |
|
Pages: |
22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jang JC |
Year: |
2000 |
Journal: |
Genes Dev |
Title: |
A critical role of sterols in embryonic patterning and meristem programming revealed by the fackel mutants of Arabidopsis thaliana. |
Volume: |
14 |
Issue: |
12 |
Pages: |
1485-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aizawa H |
Year: |
2020 |
Journal: |
Glia |
Title: |
Glial glutamate transporter GLT-1 determines susceptibility to spreading depression in the mouse cerebral cortex. |
Volume: |
68 |
Issue: |
12 |
Pages: |
2631-2642 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilde JJ |
Year: |
2021 |
Journal: |
Cell |
Title: |
Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair. |
Volume: |
184 |
Issue: |
12 |
Pages: |
3267-3280.e18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roy DS |
Year: |
2022 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Anterior thalamic circuits crucial for working memory. |
Volume: |
119 |
Issue: |
20 |
Pages: |
e2118712119 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cui W |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
Glial dysfunction in the mouse habenula causes depressive-like behaviors and sleep disturbance. |
Volume: |
34 |
Issue: |
49 |
Pages: |
16273-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ito Y |
Year: |
2009 |
Journal: |
Neurobiol Dis |
Title: |
Involvement of CHOP, an ER-stress apoptotic mediator, in both human sporadic ALS and ALS model mice. |
Volume: |
36 |
Issue: |
3 |
Pages: |
470-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okubo K |
Year: |
2001 |
Journal: |
Endocrinology |
Title: |
Identification and characterization of two distinct GnRH receptor subtypes in a teleost, the medaka Oryzias latipes. |
Volume: |
142 |
Issue: |
11 |
Pages: |
4729-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Onodera M |
Year: |
2021 |
Journal: |
J Neurosci |
Title: |
Exacerbation of Epilepsy by Astrocyte Alkalization and Gap Junction Uncoupling. |
Volume: |
41 |
Issue: |
10 |
Pages: |
2106-2118 |
|
•
•
•
•
•
|
Publication |
First Author: |
Furuya F |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Ligand-bound thyroid hormone receptor contributes to reprogramming of pancreatic acinar cells into insulin-producing cells. |
Volume: |
288 |
Issue: |
22 |
Pages: |
16155-66 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the N-terminal domain of the axin interactor, dorsalization-associated protein family AIDA []. AIDA acts as a ventralizing factor during embryogenesis. It inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by axin/JNK-signaling []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
21
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Homologous_superfamily |
Description: |
This entry represents the N-terminal domain of the axin interactor, dorsalization-associated protein (AIDA) superfamily []. AIDA acts as a ventralizing factor during embryogenesis. It inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by axin/JNK-signaling []. The core structure of the AIDA N-terminal domain consists of four helices arranged in a close or partly open bundle fold with left-handed twist going up-and-down. |
|
•
•
•
•
•
|
Publication |
First Author: |
Oshima S |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells. |
Volume: |
24 |
Issue: |
14 |
Pages: |
6298-310 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyasaka Y |
Year: |
2018 |
Journal: |
BMC Genomics |
Title: |
CLICK: one-step generation of conditional knockout mice. |
Volume: |
19 |
Issue: |
1 |
Pages: |
318 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cui W |
Year: |
2020 |
Journal: |
J Neurosci |
Title: |
Dopaminergic Signaling in the Nucleus Accumbens Modulates Stress-Coping Strategies during Inescapable Stress. |
Volume: |
40 |
Issue: |
38 |
Pages: |
7241-7254 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kasagi Y |
Year: |
2017 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Impaired degradation of medullary WNK4 in the kidneys of KLHL2 knockout mice. |
Volume: |
487 |
Issue: |
2 |
Pages: |
368-374 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sato-Nishiwaki M |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Reduced number and morphofunctional change of alveolar macrophages in MafB gene-targeted mice. |
Volume: |
8 |
Issue: |
9 |
Pages: |
e73963 |
|
•
•
•
•
•
|
Publication |
First Author: |
Isoda T |
Year: |
2017 |
Journal: |
Cell |
Title: |
Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. |
Volume: |
171 |
Issue: |
1 |
Pages: |
103-119.e18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kato T |
Year: |
1996 |
Journal: |
Arch Virol |
Title: |
Inactivation of hepatitis C virus cDNA transgene by hypermethylation in transgenic mice. |
Volume: |
141 |
Issue: |
5 |
Pages: |
951-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng LS |
Year: |
2014 |
Journal: |
FEBS J |
Title: |
Structure and mechanism of the unique C2 domain of Aida. |
Volume: |
281 |
Issue: |
20 |
Pages: |
4622-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vincent J |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. |
Volume: |
8 |
Issue: |
1 |
Pages: |
750 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roy DS |
Year: |
2021 |
Journal: |
Neuron |
Title: |
Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models. |
Volume: |
109 |
Issue: |
16 |
Pages: |
2590-2603.e13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eshiba S |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
Stem cell spreading dynamics intrinsically differentiate acral melanomas from nevi. |
Volume: |
36 |
Issue: |
5 |
Pages: |
109492 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roy DS |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Brain-wide mapping reveals that engrams for a single memory are distributed across multiple brain regions. |
Volume: |
13 |
Issue: |
1 |
Pages: |
1799 |
|
•
•
•
•
•
|
Publication |
First Author: |
Owa T |
Year: |
2018 |
Journal: |
J Neurosci |
Title: |
Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation. |
Volume: |
38 |
Issue: |
5 |
Pages: |
1277-1294 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takarada-Iemata M |
Year: |
2018 |
Journal: |
Glia |
Title: |
N-myc downstream-regulated gene 2 protects blood-brain barrier integrity following cerebral ischemia. |
Volume: |
66 |
Issue: |
7 |
Pages: |
1432-1446 |
|
•
•
•
•
•
|
Publication |
First Author: |
Otzen D |
Year: |
2012 |
Journal: |
Mol Microbiol |
Title: |
N for AsN - O for strOcture? A strand-loop-strand motif for prokaryotic O-glycosylation. |
Volume: |
83 |
Issue: |
5 |
Pages: |
879-83 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Both Aah (autotransporter adhesin heptosyltransferase) and TibC are protein O-heptosyltransferases that act on multiple sites from repeat regions of proteins exported by autotransporters. Aah glycosylates AIDA (autotransporter adhesin involved in diffuse adherence) and TibC acts on TibA (enterotoxigenic invasion locus B). TibC is able to replace Aah, suggesting that both represent a novel class of heptosyltransferases specifically transferring heptose residues onto multiple sites of a protein backbone [, ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Quadros RM |
Year: |
2017 |
Journal: |
Genome Biol |
Title: |
Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins. |
Volume: |
18 |
Issue: |
1 |
Pages: |
92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hasegawa H |
Year: |
2016 |
Journal: |
Atherosclerosis |
Title: |
The role of macrophage transcription factor MafB in atherosclerotic plaque stability. |
Volume: |
250 |
|
Pages: |
133-43 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
305
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
The axin interaction dorsalization-associated (Aida) protein was characterised in zebrafish as a protein that utilizes its C-terminal region to interact with axis formation inhibitor (Axin), which is a microtubule-interacting scaffold protein for several distinct signalling proteins in the Wnt cascade. The C-terminal region of the Aida protein is a distinct version of the C2 domain. This Aida-type C2 domain is found in the C-terminal region of the proteins and it is critical for interactions with cytoskeletal in the context of cellular adhesion points, thus, it is combined with diverse domains related to cytoskeletal functions, e.g. EF hands, coiled coils, IQ calmodulin-binding motifs, ankyrin repeats and myosin head motor domain, or with a second lipid-binding domain, e.g. the PH domain. The Aida-type C2 domain is found only in the metazoan, choanoflagellate, chromist and chlorophyte lineages [, ].This domain has predominantly a β-strand globular fold composed of an antiparallel β-sandwich with two β-sheets, and three short α-helices to stabilize the conformation []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Sekiguchi M |
Year: |
2020 |
Journal: |
Transl Psychiatry |
Title: |
ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk. |
Volume: |
10 |
Issue: |
1 |
Pages: |
247 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gubellini P |
Year: |
2001 |
Journal: |
Neuropharmacology |
Title: |
Selective involvement of mGlu1 receptors in corticostriatal LTD. |
Volume: |
40 |
Issue: |
7 |
Pages: |
839-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yasumatsu K |
Year: |
2015 |
Journal: |
J Physiol |
Title: |
Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice. |
Volume: |
593 |
Issue: |
4 |
Pages: |
1021-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang D |
Year: |
2010 |
Journal: |
Gene |
Title: |
Identification of novel families and classification of the C2 domain superfamily elucidate the origin and evolution of membrane targeting activities in eukaryotes. |
Volume: |
469 |
Issue: |
1-2 |
Pages: |
18-30 |
|
•
•
•
•
•
|