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Search results 301 to 318 out of 318 for Bin1

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0.017s
Type Details Score
Allele
Name: bridging integrator 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Publication
First Author: Ramalingam A
Year: 2007
Journal: Cell Cycle
Title: Bin1 interacts with and restrains the DNA end-binding protein complex Ku.
Volume: 6
Issue: 15
Pages: 1914-8
Publication
First Author: Perdigão C
Year: 2021
Journal: J Biol Chem
Title: Alzheimer's disease BIN1 coding variants increase intracellular Aβ levels by interfering with BACE1 recycling.
Volume: 297
Issue: 3
Pages: 101056
Publication
First Author: Owen DJ
Year: 1998
Journal: EMBO J
Title: Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation.
Volume: 17
Issue: 18
Pages: 5273-85
Publication
First Author: Nicot AS
Year: 2007
Journal: Nat Genet
Title: Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy.
Volume: 39
Issue: 9
Pages: 1134-9
Publication
First Author: Butler MH
Year: 1997
Journal: J Cell Biol
Title: Amphiphysin II (SH3P9; BIN1), a member of the amphiphysin/Rvs family, is concentrated in the cortical cytomatrix of axon initial segments and nodes of ranvier in brain and around T tubules in skeletal muscle.
Volume: 137
Issue: 6
Pages: 1355-67
Publication
First Author: Ramjaun AR
Year: 1998
Journal: J Neurochem
Title: Multiple amphiphysin II splice variants display differential clathrin binding: identification of two distinct clathrin-binding sites.
Volume: 70
Issue: 6
Pages: 2369-76
Protein Domain
Type: Domain
Description: Amphiphysin 2, also known as Bin1, is localized in many different tissues and may function in intracellular vesicle trafficking []. It plays a role in the organization and maintenance of the T-tubule network in skeletal muscle []. Mutations in Bin1 are associated with autosomal recessive centronuclear myopathy []. Bin1 contains an N-terminal BAR domain with an additional N-terminal amphipathic helix (an N-BAR) and a C-terminal SH3 domain.The SH3 domain of Bin1 forms transient complexes with actin, myosin filaments, and CDK5, to facilitate sarcomere organization and myofibre maturation []. It also binds dynamin and prevents its self-assembly [].
Protein Domain
Type: Domain
Description: This entry represents the N-terminal regions of several plant transcription factors. It is classified as BES1/BZR1, a plant-specific transcription factor that cooperates with transcription factors such as BIM1 to regulate brassinosteroid-induced genes [].Proteins containing this domain are transcriptional repressors involved in controlling the response to Brassinosteroids (BRs). BRs are plant hormones that play essential roles in growth and development. BZR1 binds directly to DNA repressing the synthesis of genes involved in BR synthesis. Phosphorylation of BZR1 by BIN1 targets BZR1 to the 20S proteosome, while dephosphorylation leads to nuclear accumulation of BZR1 [].
Publication
First Author: He JX
Year: 2005
Journal: Science
Title: BZR1 is a transcriptional repressor with dual roles in brassinosteroid homeostasis and growth responses.
Volume: 307
Issue: 5715
Pages: 1634-8
Publication
First Author: Yin Y
Year: 2005
Journal: Cell
Title: A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
Volume: 120
Issue: 2
Pages: 249-59
Publication  
First Author: Karlina R
Year: 2021
Journal: Life Sci Alliance
Title: Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice.
Volume: 4
Issue: 1
Publication
First Author: Posey AD Jr
Year: 2014
Journal: Dev Biol
Title: EHD1 mediates vesicle trafficking required for normal muscle growth and transverse tubule development.
Volume: 387
Issue: 2
Pages: 179-90
Publication
First Author: Demonbreun AR
Year: 2015
Journal: PLoS One
Title: Eps 15 Homology Domain (EHD)-1 Remodels Transverse Tubules in Skeletal Muscle.
Volume: 10
Issue: 9
Pages: e0136679
Publication
First Author: Zhou Y
Year: 2014
Journal: PLoS One
Title: Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease.
Volume: 9
Issue: 7
Pages: e103187
Protein
Organism: Mus musculus/domesticus
Length: 588  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 477  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 410  
Fragment?: false