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Search results 1 to 95 out of 95 for Nnt

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Category: Publication
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Type Details Score
Publication
34233163 | J:328623
First Author: Allouche J
Year: 2021
Journal: Cell
Title: NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism.
Volume: 184
Issue: 16
Pages: 4268-4283.e20
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Publication
22634753 | J:185986
First Author: Meimaridou E
Year: 2012
Journal: Nat Genet
Title: Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency.
Volume: 44
Issue: 7
Pages: 740-2
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Publication
29046340 | J:278564
First Author: Meimaridou E
Year: 2018
Journal: J Endocrinol
Title: NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice.
Volume: 236
Issue: 1
Pages: 13-28
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Publication
32213617 | J:287274
 
First Author: Williams JL
Year: 2020
Journal: Life Sci Alliance
Title: Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not.
Volume: 3
Issue: 4
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Publication
35119362 | J:321166
   
First Author: Rawle DJ
Year: 2022
Journal: Elife
Title: Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies.
Volume: 11
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Publication
16804088 | J:109356
First Author: Freeman HC
Year: 2006
Journal: Diabetes
Title: Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice.
Volume: 55
Issue: 7
Pages: 2153-6
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Publication
16399503 | J:108421
First Author: Freeman H
Year: 2006
Journal: Cell Metab
Title: Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion.
Volume: 3
Issue: 1
Pages: 35-45
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Publication
26256392 | J:228094
First Author: Nickel AG
Year: 2015
Journal: Cell Metab
Title: Reversal of Mitochondrial Transhydrogenase Causes Oxidative Stress in Heart Failure.
Volume: 22
Issue: 3
Pages: 472-84
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Publication
29850793 | J:317417
First Author: Chortis V
Year: 2018
Journal: Endocrinology
Title: Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma.
Volume: 159
Issue: 8
Pages: 2836-2849
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Publication
19906813 | J:168281
First Author: Wong N
Year: 2010
Journal: Endocrinology
Title: The deletion variant of nicotinamide nucleotide transhydrogenase (Nnt) does not affect insulin secretion or glucose tolerance.
Volume: 151
Issue: 1
Pages: 96-102
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Publication
32781052 | J:297705
 
First Author: Bicego R
Year: 2020
Journal: Arch Biochem Biophys
Title: Undesirable effects of chemical inhibitors of NAD(P)+ transhydrogenase on mitochondrial respiratory function.
Volume: 692
Pages: 108535
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Publication
23747984 | J:205166
 
First Author: Ronchi JA
Year: 2013
Journal: Free Radic Biol Med
Title: A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities.
Volume: 63
Pages: 446-56
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Publication
27474736 | J:237050
First Author: Ronchi JA
Year: 2016
Journal: J Biol Chem
Title: The Contribution of Nicotinamide Nucleotide Transhydrogenase to Peroxide Detoxification Is Dependent on the Respiratory State and Counterbalanced by Other Sources of NADPH in Liver Mitochondria.
Volume: 291
Issue: 38
Pages: 20173-87
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Publication
22593545 | J:187454
First Author: Ripoll VM
Year: 2012
Journal: FASEB J
Title: Nicotinamide nucleotide transhydrogenase (NNT) acts as a novel modulator of macrophage inflammatory responses.
Volume: 26
Issue: 8
Pages: 3550-62
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Publication
30281804 | J:267981
First Author: Francisco A
Year: 2018
Journal: J Neurochem
Title: Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet.
Volume: 147
Issue: 5
Pages: 663-677
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Publication
25643703 | J:224571
First Author: Fisher-Wellman KH
Year: 2015
Journal: Biochem J
Title: Pyruvate dehydrogenase complex and nicotinamide nucleotide transhydrogenase constitute an energy-consuming redox circuit.
Volume: 467
Issue: 2
Pages: 271-80
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Publication
29455203 | J:273737
First Author: Vozenilek AE
Year: 2018
Journal: J Vasc Res
Title: Absence of Nicotinamide Nucleotide Transhydrogenase in C57BL/6J Mice Exacerbates Experimental Atherosclerosis.
Volume: 55
Issue: 2
Pages: 98-110
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Publication
17922105 | J:129498
First Author: Aston-Mourney K
Year: 2007
Journal: Diabetologia
Title: Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes.
Volume: 50
Issue: 12
Pages: 2476-85
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Publication
28964917 | J:319248
 
First Author: Navarro CDC
Year: 2017
Journal: Free Radic Biol Med
Title: Redox imbalance due to the loss of mitochondrial NAD(P)-transhydrogenase markedly aggravates high fat diet-induced fatty liver disease in mice.
Volume: 113
Pages: 190-202
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Publication
22384386 | J:186862
First Author: Navarro SJ
Year: 2012
Journal: G3 (Bethesda)
Title: The C57BL/6J Mouse Strain Background Modifies the Effect of a Mutation in Bcl2l2.
Volume: 2
Issue: 1
Pages: 99-102
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Publication
19161594 | J:144487
First Author: Anderson AA
Year: 2009
Journal: Pathogenetics
Title: Pancreatic islet expression profiling in diabetes-prone C57BLKS/J mice reveals transcriptional differences contributed by DBA loci, including Plagl1 and Nnt.
Volume: 2
Issue: 1
Pages: 1
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Publication
32748289 | J:319328
First Author: Wagner M
Year: 2020
Journal: Basic Res Cardiol
Title: Selective NADH communication from α-ketoglutarate dehydrogenase to mitochondrial transhydrogenase prevents reactive oxygen species formation under reducing conditions in the heart.
Volume: 115
Issue: 5
Pages: 53
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Publication
32196080 | J:289864
 
First Author: Ward NP
Year: 2020
Journal: J Exp Med
Title: Nicotinamide nucleotide transhydrogenase regulates mitochondrial metabolism in NSCLC through maintenance of Fe-S protein function.
Volume: 217
Issue: 6
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Publication
31803904 | J:282801
First Author: Salerno AG
Year: 2019
Journal: Biochem J
Title: Lack of mitochondrial NADP(H)-transhydrogenase expression in macrophages exacerbates atherosclerosis in hypercholesterolemic mice.
Volume: 476
Issue: 24
Pages: 3769-3789
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Publication
21069343 | J:166767
First Author: Kim A
Year: 2010
Journal: Mamm Genome
Title: Genetic modifier of mitochondrial superoxide dismutase-deficient mice delays heart failure and prolongs survival.
Volume: 21
Issue: 11-12
Pages: 534-42
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Publication
19539600 | J:153452
First Author: Parker N
Year: 2009
Journal: Biochim Biophys Acta
Title: Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.
Volume: 1787
Issue: 12
Pages: 1451-7
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Publication
27428041 | J:238764
First Author: Son MJ
Year: 2016
Journal: Stem Cells
Title: Restoration of Mitochondrial NAD+ Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells.
Volume: 34
Issue: 12
Pages: 2840-2851
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Publication
16497723 | J:108213
First Author: Huang TT
Year: 2006
Journal: Hum Mol Genet
Title: Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase.
Volume: 15
Issue: 7
Pages: 1187-94
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Publication
15729571 | J:106692
First Author: Toye AA
Year: 2005
Journal: Diabetologia
Title: A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.
Volume: 48
Issue: 4
Pages: 675-86
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Publication
8616157 | J:32221
First Author: Arkblad EL
Year: 1996
Journal: Biochim Biophys Acta
Title: The cDNA sequence of proton-pumping nicotinamide nucleotide transhydrogenase from man and mouse.
Volume: 1273
Issue: 3
Pages: 203-5
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Publication
23845568 | J:200602
First Author: Ulmasov B
Year: 2013
Journal: Am J Pathol
Title: Differences in the degree of cerulein-induced chronic pancreatitis in C57BL/6 mouse substrains lead to new insights in identification of potential risk factors in the development of chronic pancreatitis.
Volume: 183
Issue: 3
Pages: 692-708
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Publication
9271681 | J:42376
First Author: Arkblad EL
Year: 1997
Journal: Mamm Genome
Title: Mapping of the rat and mouse nicotinamide nucleotide transhydrogenase gene.
Volume: 8
Issue: 9
Pages: 703
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Publication
32747443 | J:299471
First Author: Smith CD
Year: 2020
Journal: J Biol Chem
Title: Flux through mitochondrial redox circuits linked to nicotinamide nucleotide transhydrogenase generates counterbalance changes in energy expenditure.
Volume: 295
Issue: 48
Pages: 16207-16216
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Publication
29563328 | J:285526
 
First Author: Moreno-Fernandez ME
Year: 2018
Journal: JCI Insight
Title: Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease.
Volume: 3
Issue: 6
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Publication
27907040 | J:254884
First Author: Llano-Diez M
Year: 2016
Journal: PLoS One
Title: The Role of Reactive Oxygen Species in β-Adrenergic Signaling in Cardiomyocytes from Mice with the Metabolic Syndrome.
Volume: 11
Issue: 12
Pages: e0167090
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Publication
30716103 | J:270773
First Author: Kakimoto PA
Year: 2019
Journal: PLoS One
Title: Resilient hepatic mitochondrial function and lack of iNOS dependence in diet-induced insulin resistance.
Volume: 14
Issue: 2
Pages: e0211733
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Publication
32473019 | J:293893
 
First Author: Duggan BM
Year: 2020
Journal: Endocrinology
Title: RIPK2 Dictates Insulin Responses to Tyrosine Kinase Inhibitors in Obese Male Mice.
Volume: 161
Issue: 8
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Publication
33484949 | J:297264
 
First Author: Croze ML
Year: 2021
Journal: Mol Metab
Title: Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice.
Volume: 45
Pages: 101166
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Publication
27050514 | J:234946
First Author: Lin-Hendel EG
Year: 2016
Journal: Cell Rep
Title: Differential Mitochondrial Requirements for Radially and Non-radially Migrating Cortical Neurons: Implications for Mitochondrial Disorders.
Volume: 15
Issue: 2
Pages: 229-37
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Publication
9670959 | J:48583
First Author: Zuberi AR
Year: 1998
Journal: J Immunol
Title: Expression screening of a yeast artificial chromosome contig refines the location of the mouse H3a minor histocompatibility antigen gene.
Volume: 161
Issue: 2
Pages: 821-8
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Publication
15457338 | J:93069
First Author: Quwailid MM
Year: 2004
Journal: Mamm Genome
Title: A gene-driven ENU-based approach to generating an allelic series in any gene.
Volume: 15
Issue: 8
Pages: 585-91
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Publication
31505254 | J:295435
 
First Author: Yli-Karjanmaa M
Year: 2019
Journal: Brain Behav Immun
Title: TNF deficiency causes alterations in the spatial organization of neurogenic zones and alters the number of microglia and neurons in the cerebral cortex.
Volume: 82
Pages: 279-297
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Publication
14973295 | J:88577
First Author: Mu X
Year: 2004
Journal: Development
Title: Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina.
Volume: 131
Issue: 6
Pages: 1197-210
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Publication
10464095 | J:57234
First Author: Lee CK
Year: 1999
Journal: Science
Title: Gene expression profile of aging and its retardation by caloric restriction.
Volume: 285
Issue: 5432
Pages: 1390-3
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12865426 | J:100953
First Author: Da Cruz S
Year: 2003
Journal: J Biol Chem
Title: Proteomic analysis of the mouse liver mitochondrial inner membrane.
Volume: 278
Issue: 42
Pages: 41566-71
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
31698702 | -
 
First Author: Rohman A
Year: 2019
Journal: Int J Mol Sci
Title: β-Xylosidases: Structural Diversity, Catalytic Mechanism, and Inhibition by Monosaccharides.
Volume: 20
Issue: 22
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31165767 | J:294547
First Author: Pastille E
Year: 2019
Journal: Mucosal Immunol
Title: The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer.
Volume: 12
Issue: 4
Pages: 990-1003
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Publication
37118338 | J:344336
First Author: Zhu FY
Year: 2021
Journal: Nat Aging
Title: Inhibiting bridge integrator 2 phosphorylation leads to improved oocyte quality, ovarian health and fertility in aging and after chemotherapy in mice.
Volume: 1
Issue: 11
Pages: 1010-1023
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24655393 | J:217239
First Author: Ghosh D
Year: 2014
Journal: Aging Cell
Title: Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons.
Volume: 13
Issue: 4
Pages: 631-40
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19448337 | J:160204
First Author: Mekada K
Year: 2009
Journal: Exp Anim
Title: Genetic differences among C57BL/6 substrains.
Volume: 58
Issue: 2
Pages: 141-9
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25506550 | J:223529
First Author: Fergusson G
Year: 2014
Journal: Mol Metab
Title: Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice.
Volume: 3
Issue: 9
Pages: 848-54
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Publication
27495226 | J:269107
First Author: Fisher-Wellman KH
Year: 2016
Journal: Diabetes
Title: A Direct Comparison of Metabolic Responses to High-Fat Diet in C57BL/6J and C57BL/6NJ Mice.
Volume: 65
Issue: 11
Pages: 3249-3261
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Publication
28138002 | J:266358
First Author: Hull RL
Year: 2017
Journal: J Endocrinol
Title: High fat feeding unmasks variable insulin responses in male C57BL/6 mouse substrains.
Volume: 233
Issue: 1
Pages: 53-64
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Publication
32497756 | J:298660
 
First Author: Francisco A
Year: 2020
Journal: Neuroscience
Title: Mitochondrial NAD(P)+ Transhydrogenase is Unevenly Distributed in Different Brain Regions, and its Loss Causes Depressive-like Behavior and Motor Dysfunction in Mice.
Volume: 440
Pages: 210-229
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Publication
21558310 | J:174892
First Author: Nakamura BN
Year: 2011
Journal: Endocrinology
Title: Lack of maternal glutamate cysteine ligase modifier subunit (Gclm) decreases oocyte glutathione concentrations and disrupts preimplantation development in mice.
Volume: 152
Issue: 7
Pages: 2806-15
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Publication
36548271 | J:333697
First Author: Nemoto S
Year: 2022
Journal: PLoS One
Title: Metabolic differences and differentially expressed genes between C57BL/6J and C57BL/6N mice substrains.
Volume: 17
Issue: 12
Pages: e0271651
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Publication
34448880 | J:315691
First Author: Close AF
Year: 2021
Journal: Diabetologia
Title: The lack of functional nicotinamide nucleotide transhydrogenase only moderately contributes to the impairment of glucose tolerance and glucose-stimulated insulin secretion in C57BL/6J vs C57BL/6N mice.
Volume: 64
Issue: 11
Pages: 2550-2561
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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