This region of sequence similarity is found up to six times in a variety of proteins including general transcription factor II-I (GTF2I). It has been suggested that this may be a DNA binding domain [, ].
This region of sequence similarity is found up to six times in a variety of proteins including general transcription factor II-I (GTF2I). It has been suggested that this may be a DNA binding domain [, ].The structure of each GTF2I repeat is composed of an alpha(2)-beta-α-β-alpha fold arranged in two layers (alpha/beta) with antiparallel β-ribbon.
