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Search results 401 to 435 out of 435 for Grm7

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0.019s

Type

Details

Score

Publication

- | J:63103

First Author:	Mouse Genome Database and National Center for Biotechnology Information
Year:	2000
Journal:	Database Release
Title:	Entrez Gene Load

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Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

•

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

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Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

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Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

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Publication

34616277 | J:312733

First Author:	Barón-Mendoza I
Year:	2021
Journal:	Front Cell Neurosci
Title:	Changes in the Number and Morphology of Dendritic Spines in the Hippocampus and Prefrontal Cortex of the C58/J Mouse Model of Autism.
Volume:	15

Pages:	726501

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Publication

8840028 | -

First Author:	Makoff A
Year:	1996
Journal:	Brain Res Mol Brain Res
Title:	Human metabotropic glutamate receptor type 7: molecular cloning and mRNA distribution in the CNS.
Volume:	40
Issue:	1
Pages:	165-70

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Publication

8288585 | -

First Author:	Okamoto N
Year:	1994
Journal:	J Biol Chem
Title:	Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction.
Volume:	269
Issue:	2
Pages:	1231-6

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Protein Domain

IPR001883 | GPCR_3_mGluR7

Type:

Family

Description:

G protein-coupled receptors (GPCRs) constitute a vast protein family that encompasses a wide range of functions, including various autocrine, paracrine and endocrine processes. They show considerable diversity at the sequence level, on the basis of which they can be separated into distinct groups []. The term clan can be used to describe the GPCRs, as they embrace a group of families for which there are indications of evolutionary relationship, but between which there is no statistically significant similarity in sequence []. The currently known clan members include rhodopsin-like GPCRs (Class A, GPCRA), secretin-like GPCRs (Class B, GPCRB), metabotropic glutamate receptor family (Class C, GPCRC), fungal mating pheromone receptors (Class D, GPCRD), cAMP receptors (Class E, GPCRE) and frizzled/smoothened (Class F, GPCRF) [, , , , ]. GPCRs are major drug targets, and are consequently the subject of considerable research interest. It has been reported that the repertoire of GPCRs for endogenous ligands consists of approximately 400 receptors in humans and mice []. Most GPCRs are identified on the basis of their DNA sequences, rather than the ligand they bind, those that are unmatched to known natural ligands are designated by as orphan GPCRs, or unclassified GPCRs [].GPCR family 3 receptors (also known as family C) are structurally similar to other GPCRs, but do not show any significant sequence similarity and thus represent a distinct group. Structurally they are composed of four elements; an N-terminal signal sequence; a large hydrophilic extracellular agonist-binding region containing several conserved cysteine residues which could be involved in disulphide bonds; a shorter region containing seven transmembrane domains; and a C-terminal cytoplasmic domain of variable length []. Family 3 members include the metabotropic glutamate receptors, the extracellular calcium-sensing receptors, the gamma-amino-butyric acid (GABA) type B receptors, and the vomeronasal type-2 receptors [, , , ]. As these receptors regulate many important physiological processes they are potentially promising targets for drug development.The metabotropic glutamate receptors are functionally and pharmacologically distinct from the ionotropic glutamate receptors. They are coupled to G-proteins and stimulate the inositol phosphate/Ca2+intracellular signalling pathway [, , , ]. At least eight sub-types of metabotropic receptor (GRM1-8) have been identified in cloning studies. The sub-types differ in their agonist pharmacology and signal transduction pathways.GRM7 mRNA has a widespread distribution in many neuronal cells of the central nervoussystem, with highest levels in the hippocampal formation, cerebral cortexand cerebellum [, ]; it is thus different from the more limitedly expressedGRM4 or GRM6 mRNA []. GRM7 and GRM4 are believed to correspond to theputative L-2-amino-4-phosphonobutyrate receptor, which plays an importantrole in modulation of glutamate transmission in the CNS [].

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Protein

G3UZU3

Organism:	Mus musculus/domesticus
Length:	188
Fragment?:	false

•

Protein

Q8BL09

Organism:	Mus musculus/domesticus
Length:	209
Fragment?:	false

•

Protein

Q8BKZ1

Organism:	Mus musculus/domesticus
Length:	381
Fragment?:	true

•

Protein

Q8BKE3

Organism:	Mus musculus/domesticus
Length:	361
Fragment?:	false

•

Protein

Q68ED2

Organism:	Mus musculus/domesticus
Length:	915
Fragment?:	false

•

Protein

G5E8D5

Organism:	Mus musculus/domesticus
Length:	922
Fragment?:	false

•

Publication

1320017 | -

First Author:	Abe T
Year:	1992
Journal:	J Biol Chem
Title:	Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.
Volume:	267
Issue:	19
Pages:	13361-8

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Publication

1847995 | -

First Author:	Masu M
Year:	1991
Journal:	Nature
Title:	Sequence and expression of a metabotropic glutamate receptor.
Volume:	349
Issue:	6312
Pages:	760-5

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Publication

1656524 | -

First Author:	Houamed KM
Year:	1991
Journal:	Science
Title:	Cloning, expression, and gene structure of a G protein-coupled glutamate receptor from rat brain.
Volume:	252
Issue:	5010
Pages:	1318-21

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Publication

10773016 | -

First Author:	Sullivan R
Year:	2000
Journal:	J Pharmacol Exp Ther
Title:	Coexpression of full-length gamma-aminobutyric acid(B) (GABA(B)) receptors with truncated receptors and metabotropic glutamate receptor 4 supports the GABA(B) heterodimer as the functional receptor.
Volume:	293
Issue:	2
Pages:	460-7

•

Publication

9292726 | J:42626

First Author:	Ryba NJ
Year:	1997
Journal:	Neuron
Title:	A new multigene family of putative pheromone receptors.
Volume:	19
Issue:	2
Pages:	371-9

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Publication

17266540 | -

First Author:	Bräuner-Osborne H
Year:	2007
Journal:	Curr Drug Targets
Title:	Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors.
Volume:	8
Issue:	1
Pages:	169-84

•

Publication

8255296 | -

First Author:	Brown EM
Year:	1993
Journal:	Nature
Title:	Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid.
Volume:	366
Issue:	6455
Pages:	575-80

•

Publication

1309649 | -

First Author:	Tanabe Y
Year:	1992
Journal:	Neuron
Title:	A family of metabotropic glutamate receptors.
Volume:	8
Issue:	1
Pages:	169-79

•

Publication

12679517 | J:83410

First Author:	Vassilatis DK
Year:	2003
Journal:	Proc Natl Acad Sci U S A
Title:	The G protein-coupled receptor repertoires of human and mouse.
Volume:	100
Issue:	8
Pages:	4903-8

•

Publication

8170923 | -

First Author:	Attwood TK
Year:	1994
Journal:	Protein Eng
Title:	Fingerprinting G-protein-coupled receptors.
Volume:	7
Issue:	2
Pages:	195-203

•

Publication

8081729 | -

First Author:	Kolakowski LF Jr
Year:	1994
Journal:	Receptors Channels
Title:	GCRDb: a G-protein-coupled receptor database.
Volume:	2
Issue:	1
Pages:	1-7

•

Publication

15914470 | -

First Author:	Foord SM
Year:	2005
Journal:	Pharmacol Rev
Title:	International Union of Pharmacology. XLVI. G protein-coupled receptor list.
Volume:	57
Issue:	2
Pages:	279-88

•

Publication

18948278 | -

First Author:	Harmar AJ
Year:	2009
Journal:	Nucleic Acids Res
Title:	IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels.
Volume:	37
Issue:	Database issue
Pages:	D680-5

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Publication

16753280 | J:115055

First Author:	Bjarnadóttir TK
Year:	2006
Journal:	Genomics
Title:	Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse.
Volume:	88
Issue:	3
Pages:	263-73

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Publication

23020293 | -

First Author:	Civelli O
Year:	2013
Journal:	Annu Rev Pharmacol Toxicol
Title:	G protein-coupled receptor deorphanizations.
Volume:	53

Pages:	127-46

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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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