Budding yeast Bud22 is required for rRNA maturation and ribosomal subunit biogenesis [, ]. Serum response factor-binding protein 1 (SRFB1) is Bud22 homologue in animals. SRFB1 may be involved in regulating transcriptional activation of cardiac genes during the aging process and may play a role in biosynthesis and/or processing of SLC2A4 in adipose cells [, ].
This entry represents a domain found in the fungal Bud22 protein and the animal SRFB1 (serum response factor-binding protein 1) protein. Budding yeast Bud22 is required for rRNA maturation and ribosomal subunit biogenesis [, ]. SRFB1 may be involved in regulating transcriptional activation of cardiac genes during the aging process and may play a role in biosynthesis and/or processing of SLC2A4 in adipose cells [, ].