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Search results 601 to 700 out of 904 for Crh

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Type Details Score
Heritable Phenotypic Marker
MGI:88499 | crhx
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Publication
20881239 | J:310755
First Author: Matsuwaki T
Year: 2010
Journal: Endocrinology
Title: Functional hypothalamic amenorrhea due to increased CRH tone in melanocortin receptor 2-deficient mice.
Volume: 151
Issue: 11
Pages: 5489-96
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Publication
37848038 | J:343739
First Author: Li SY
Year: 2023
Journal: Curr Biol
Title: CRH neurons in the lateral hypothalamic area regulate feeding behavior of mice.
Volume: 33
Issue: 22
Pages: 4827-4843.e7
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Publication
29346768 | J:270696
First Author: Okamoto S
Year: 2018
Journal: Cell Rep
Title: Activation of AMPK-Regulated CRH Neurons in the PVH is Sufficient and Necessary to Induce Dietary Preference for Carbohydrate over Fat.
Volume: 22
Issue: 3
Pages: 706-721
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Publication
18695245 | J:139705
First Author: Kolber BJ
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Central amygdala glucocorticoid receptor action promotes fear-associated CRH activation and conditioning.
Volume: 105
Issue: 33
Pages: 12004-9
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Publication
20438764 | J:160360
First Author: Frisch P
Year: 2010
Journal: Behav Brain Res
Title: Modulation of the CRH system by substance P/NKA in an animal model of depression.
Volume: 213
Issue: 1
Pages: 103-8
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Publication
12884973 | J:130551
First Author: van Gaalen MM
Year: 2002
Journal: Genes Brain Behav
Title: Mice overexpressing CRH show reduced responsiveness in plasma corticosterone after a5-HT1A receptor challenge.
Volume: 1
Issue: 3
Pages: 174-7
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Publication
17042789 | J:116995
First Author: Schmidt MV
Year: 2006
Journal: Eur J Neurosci
Title: Differential disinhibition of the neonatal hypothalamic- pituitary-adrenal axis in brain-specific CRH receptor 1-knockout mice.
Volume: 24
Issue: 8
Pages: 2291-8
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Publication
24495609 | J:223187
 
First Author: Lee V
Year: 2014
Journal: Psychoneuroendocrinology
Title: Loss of Gabrd in CRH neurons blunts the corticosterone response to stress and diminishes stress-related behaviors.
Volume: 41
Pages: 75-88
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Publication
30231016 | J:266220
First Author: Dunn-Fletcher CE
Year: 2018
Journal: PLoS Biol
Title: Anthropoid primate-specific retroviral element THE1B controls expression of CRH in placenta and alters gestation length.
Volume: 16
Issue: 9
Pages: e2006337
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Publication
32798220 | J:296427
 
First Author: Phumsatitpong C
Year: 2020
Journal: Endocrinology
Title: A CRH Receptor Type 1 Agonist Increases GABA Transmission to GnRH Neurons in a Circulating-Estradiol-Dependent Manner.
Volume: 161
Issue: 11
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Publication
11430861 | J:70428
First Author: Steckler T
Year: 2001
Journal: Brain Res
Title: Interaction between the cholinergic system and CRH in the modulation of spatial discrimination learning in mice.
Volume: 906
Issue: 1-2
Pages: 46-59
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Publication
30214395 | J:288904
 
First Author: Raftogianni A
Year: 2018
Journal: Front Mol Neurosci
Title: Deciphering the Contributions of CRH Receptors in the Brain and Pituitary to Stress-Induced Inhibition of the Reproductive Axis.
Volume: 11
Pages: 305
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Publication
20394311 | J:225031
First Author: Romanowski CP
Year: 2010
Journal: Sleep
Title: Central deficiency of corticotropin-releasing hormone receptor type 1 (CRH-R1) abolishes effects of CRH on NREM but not on REM sleep in mice.
Volume: 33
Issue: 4
Pages: 427-36
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Publication
8367033 | J:13322
First Author: de Waele JP
Year: 1993
Journal: Neuroendocrinology
Title: Effects of single and repeated exposures to ethanol on hypothalamic beta-endorphin and CRH release by the C57BL/6 and DBA/2 strains of mice.
Volume: 57
Issue: 4
Pages: 700-9
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Allele
Crh<tm1Maj> | MGI:1857392
Name: corticotropin releasing hormone; targeted mutation 1, Joseph Majzoub
Allele Type: Targeted
Attribute String: Null/knockout
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GO Term
GO:0051424 | corticotropin-releasing hormone binding
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Publication
19281799 | J:148114
 
First Author: Thammacharoen S
Year: 2009
Journal: Brain Res
Title: Divergent effects of estradiol and the estrogen receptor-alpha agonist PPT on eating and activation of PVN CRH neurons in ovariectomized rats and mice.
Volume: 1268
Pages: 88-96
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GXD Expression
GXD Expression
 
Probe: MGI:6295187
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3276728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295983
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Camk2a + Crh - Pir
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6295179
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3276728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295980
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a GAD65/67 + Crh - Pir
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6295180
Assay Type: RNA in situ
Annotation Date: 2019-05-07
Strength: Present
Sex: Male
Emaps: EMAPS:3276728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6296657
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a GAD65/67 + Crh - Pir
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6295184
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3276728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295986
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Vglut2 + Crh - Pir
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6295181
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3276728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295984
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Vglut1 + Crh - Pir
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6295187
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295983
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Camk2a + Crh - Hip-CA1
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:6295179
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295980
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a GAD65/67 + Crh - Hip-CA1
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:6295180
Assay Type: RNA in situ
Annotation Date: 2019-05-07
Strength: Present
Sex: Male
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6296657
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a GAD65/67 + Crh - Hip-CA1
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:6295184
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295986
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Vglut2 + Crh - Hip-CA1
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:6295181
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295984
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Vglut1 + Crh - Hip-CA1
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:6295187
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295983
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Camk2a + Crh - Ctx
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:6295179
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295980
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a GAD65/67 + Crh - Ctx
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:6295180
Assay Type: RNA in situ
Annotation Date: 2019-05-07
Strength: Present
Sex: Male
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6296657
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a GAD65/67 + Crh - Ctx
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:6295184
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295986
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Vglut2 + Crh - Ctx
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6295181
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295984
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Vglut1 + Crh - Ctx
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6295187
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3566528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295983
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Camk2a + Crh - PVN
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6295179
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3566528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295980
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a GAD65/67 + Crh - PVN
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6295180
Assay Type: RNA in situ
Annotation Date: 2019-05-07
Strength: Present
Sex: Male
Emaps: EMAPS:3566528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6296657
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a GAD65/67 + Crh - PVN
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6295184
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3566528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295986
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Vglut2 + Crh - PVN
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6295181
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3566528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295984
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Vglut1 + Crh - PVN
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6295187
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295983
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: 2a Camk2a + Crh - lower
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6295187
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295983
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Camk2a + Crh - CeA
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:6295179
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295980
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: 1c Gad65/67 + Crh - lower
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6295179
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295980
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a GAD65/67 + Crh - CeA
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:6295180
Assay Type: RNA in situ
Annotation Date: 2019-05-07
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6296657
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: 1c Gad65/67 + Crh - lower
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6295180
Assay Type: RNA in situ
Annotation Date: 2019-05-07
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6296657
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a GAD65/67 + Crh - CeA
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:6295189
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295988
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S4a Crh + Pkcd - left
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6295189
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295988
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S4a Crh + Pkcd - center
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6295189
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295988
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S4a Crh + Pkcd - right
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6295184
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295986
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Vglut2 + Crh - CeA
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6295181
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295984
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S3a Vglut1 + Crh - CeA
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
 
Probe: MGI:6295188
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295989
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S4a Crh + Som - left
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6295188
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295989
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S4a Crh + Som - center
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:6295188
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3520428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295989
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: S4a Crh + Som - right
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6295187
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295983
Age: postnatal week 10-14
Note: Expression is present in neurons in the anterior dorsal BNST.
Specimen Label: S3a Camk2a + Crh - adBNST
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6295187
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295983
Age: postnatal week 10-14
Note: Expression is present in neurons in the anterior ventral BNST.
Specimen Label: S3a Camk2a + Crh - avBNST
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6295187
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295983
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: 2a Camk2a + Crh - upper
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6295179
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295980
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: 1c Gad65/67 + Crh - upper
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6295179
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295980
Age: postnatal week 10-14
Note: Expression is present in neurons in the anterior dorsal BNST.
Specimen Label: S3a GAD65/67 + Crh - adBNST
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:6295179
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295980
Age: postnatal week 10-14
Note: Expression is present in neurons in the anterior ventral BNST.
Specimen Label: S3a GAD65/67 + Crh - avBNST
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6295180
Assay Type: RNA in situ
Annotation Date: 2019-05-07
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6296657
Age: postnatal week 10-14
Note: Expression is present in neurons.
Specimen Label: 1c Gad65/67 + Crh - upper
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6295180
Assay Type: RNA in situ
Annotation Date: 2019-05-07
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6296657
Age: postnatal week 10-14
Note: Expression is present in neurons in the anterior dorsal BNST.
Specimen Label: S3a GAD65/67 + Crh - adBNST
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6295180
Assay Type: RNA in situ
Annotation Date: 2019-05-07
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6296657
Age: postnatal week 10-14
Note: Expression is present in neurons in the anterior ventral BNST.
Specimen Label: S3a GAD65/67 + Crh - avBNST
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6295184
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295986
Age: postnatal week 10-14
Note: Expression is present in neurons in the anterior dorsal BNST.
Specimen Label: S3a Vglut2 + Crh - adBNST
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6295184
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295986
Age: postnatal week 10-14
Note: Expression is present in neurons in the anterior ventral BNST.
Specimen Label: S3a Vglut2 + Crh - avBNST
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6295181
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295984
Age: postnatal week 10-14
Note: Expression is present in neurons in the anterior dorsal BNST.
Specimen Label: S3a Vglut1 + Crh - adBNST
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6295181
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Male
Emaps: EMAPS:3740728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6295984
Age: postnatal week 10-14
Note: Expression is present in neurons in the anterior ventral BNST.
Specimen Label: S3a Vglut1 + Crh - avBNST
Detected: true
Specimen Num: 3
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Publication
9237995 | -
First Author: Galinier A
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: The Bacillus subtilis crh gene encodes a HPr-like protein involved in carbon catabolite repression.
Volume: 94
Issue: 16
Pages: 8439-44
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GO Term
GO:0043397 | regulation of corticotropin-releasing hormone secretion
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GO Term
GO:0043404 | corticotropin-releasing hormone receptor activity
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Publication
15705776 | J:98292
First Author: Garlow SJ
Year: 2005
Journal: Endocrinology
Title: Genetic analysis of the hypothalamic corticotropin-releasing factor system.
Volume: 146
Issue: 5
Pages: 2362-8
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Allele
Crh<em2Smoc> | MGI:7289146
Name: corticotropin releasing hormone; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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GO Term
GO:0071376 | cellular response to corticotropin-releasing hormone stimulus
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GO Term
GO:0051429 | corticotropin-releasing hormone receptor binding
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GO Term
GO:0043435 | response to corticotropin-releasing hormone
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GO Term
GO:1900010 | regulation of corticotropin-releasing hormone receptor activity
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Allele
Crh<em1Smoc> | MGI:7289145
Name: corticotropin releasing hormone; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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GO Term
GO:0051465 | negative regulation of corticotropin-releasing hormone secretion
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GO Term
GO:0017045 | corticotropin-releasing hormone activity
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Protein
Q3TPS3
Organism: Mus musculus/domesticus
Length: 42  
Fragment?: true
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Publication
12379493 | -
First Author: Seasholtz AF
Year: 2002
Journal: J Endocrinol
Title: Corticotropin-releasing hormone-binding protein: biochemistry and function from fishes to mammals.
Volume: 175
Issue: 1
Pages: 89-97
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Protein Domain
IPR008435 | CRF-bd
Type: Family
Description: This family consists of several eukaryotic corticotropin-releasing factor binding proteins (CRF-BP or CRH-BP). Corticotropin-releasing hormone (CRH) plays multiple roles in vertebrate species. In mammals, it is the major hypothalamic releasing factor for pituitary adrenocorticotropin secretion, and is a neurotransmitter or neuromodulator at other sites in the central nervous system. In non-mammalian vertebrates, CRH not only acts as a neurotransmitter and hypophysiotropin, it also acts as a potent thyrotropin-releasing factor, allowing CRH to regulate both the adrenal and thyroid axes, especially in development. CRH-BP is thought to play an inhibitory role in which it binds CRH and other CRH-like ligands and prevents the activation of CRH receptors. There is however evidence that CRH-BP may also exhibit diverse extra and intracellular roles in a cell specific fashion and at specific times in development [].
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Allele
Tg(CRH-MAPT/Topaz)1Rck | MGI:5586654
Name: transgene insertion 1, J M Friedman
Allele Type: Transgenic
Attribute String: Reporter
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Publication
9620773 | J:76022
First Author: Timpl P
Year: 1998
Journal: Nat Genet
Title: Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1.
Volume: 19
Issue: 2
Pages: 162-6
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GO Term
GO:0051466 | positive regulation of corticotropin-releasing hormone secretion
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GO Term
GO:1900011 | negative regulation of corticotropin-releasing hormone receptor activity
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GO Term
GO:1900012 | positive regulation of corticotropin-releasing hormone receptor activity
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Publication
14526225 | J:224821
First Author: Stevens SL
Year: 2003
Journal: J Cereb Blood Flow Metab
Title: Reduced cerebral injury in CRH-R1 deficient mice after focal ischemia: a potential link to microglia and atrocytes that express CRH-R1.
Volume: 23
Issue: 10
Pages: 1151-9
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Publication
11089561 | J:65573
First Author: Müller MB
Year: 2000
Journal: Endocrinology
Title: Selective activation of the hypothalamic vasopressinergic system in mice deficient for the corticotropin-releasing hormone receptor 1 is dependent on glucocorticoids.
Volume: 141
Issue: 11
Pages: 4262-9
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Publication
17854779 | J:127266
 
First Author: Schmidt MV
Year: 2007
Journal: Brain Res
Title: Ontogeny of steroid receptor coactivators in the hippocampus and their role in regulating postnatal HPA axis function.
Volume: 1174
Pages: 1-6
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Publication
12770571 | J:109403
First Author: Schmidt MV
Year: 2003
Journal: Neuroscience
Title: Regulation of the developing hypothalamic-pituitary-adrenal axis in corticotropin releasing hormone receptor 1-deficient mice.
Volume: 119
Issue: 2
Pages: 589-95
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Allele
Gt(ROSA)26Sor<tm1(Crh)Jde> | MGI:3815322
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Jan Deussing
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Strain
MGI:5586651 | B6;CBA-Tg(CRH-MAPT/Topaz)1Rck/J
Attribute String: transgenic, mutant stock
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Allele
Tg(Crh-cre)1Kres | MGI:4457114
Name: transgene insertion 1, Kerry J Ressler
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Crh-EGFP)HS57Gsat | MGI:4846965
Name: transgene insertion HS57, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Crh<tm1.1(flpo)Bsab> | MGI:6116854
Name: corticotropin releasing hormone; targeted mutation 1.1, Bernardo Sabatini
Allele Type: Targeted
Attribute String: Recombinase
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Strain
MGI:6475055 | C57BL/6-Crh<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
17293846 | J:290921
First Author: Deussing JM
Year: 2007
Journal: J Cereb Blood Flow Metab
Title: Expression profiling identifies the CRH/CRH-R1 system as a modulator of neurovascular gene activity.
Volume: 27
Issue: 8
Pages: 1476-95
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Publication
19361479 | J:148931
First Author: Silberstein S
Year: 2009
Journal: Neuroscience
Title: Amygdaloid pERK1/2 in corticotropin-releasing hormone overexpressing mice under basal and acute stress conditions.
Volume: 159
Issue: 2
Pages: 610-7
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Publication
18337421 | J:133020
First Author: Chen Y
Year: 2008
Journal: J Neurosci
Title: Rapid loss of dendritic spines after stress involves derangement of spine dynamics by corticotropin-releasing hormone.
Volume: 28
Issue: 11
Pages: 2903-11
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Publication
18708129 | J:140968
First Author: Hanstein R
Year: 2008
Journal: Neuroscience
Title: Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excitotoxic stress.
Volume: 156
Issue: 3
Pages: 712-21
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Publication
24782732 | J:225222
 
First Author: Zimprich A
Year: 2014
Journal: Front Behav Neurosci
Title: A robust and reliable non-invasive test for stress responsivity in mice.
Volume: 8
Pages: 125
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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