Monocarboxylate transporter 10 (MCT10), also known as SLC16A10 or TAT1, belongs to the MCT family. It transports aromatic amino acids (phenylalanine, tyrosine, and tryptophan) in a sodium and proton independent manner []. It has been shown to transport thyroid hormone (TH) [, ].Monocarboxylate transporters (MCTs) catalyse the proton-linked transport of monocarboxylates such as L-lactate, pyruvate, and the ketone bodies across the plasma membrane [, ]. All of the MCT family (also known as SLC16 solute carrier family) members share conserved sequence motifs. They are are predicted to have 12-transmembrane helices (TMs) with intracellular C and N termini and a large cytosolic loop between TMs 6 and 7 [].
