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Search results 101 to 200 out of 371 for Epas1

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Type Details Score
Publication
23610397 | J:197349
First Author: Yuan G
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis.
Volume: 110
Issue: 19
Pages: E1788-96
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Publication
22264788 | J:180281
First Author: Branco-Price C
Year: 2012
Journal: Cancer Cell
Title: Endothelial cell HIF-1α and HIF-2α differentially regulate metastatic success.
Volume: 21
Issue: 1
Pages: 52-65
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Publication
26731474 | J:231164
First Author: Chang YT
Year: 2016
Journal: J Clin Invest
Title: DNA methyltransferase inhibition restores erythropoietin production in fibrotic murine kidneys.
Volume: 126
Issue: 2
Pages: 721-31
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Publication
27150457 | J:253838
 
First Author: Torres-Capelli M
Year: 2016
Journal: Sci Rep
Title: Role Of Hif2α Oxygen Sensing Pathway In Bronchial Epithelial Club Cell Proliferation.
Volume: 6
Pages: 25357
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Publication
23785149 | J:199643
First Author: Huang Z
Year: 2013
Journal: J Neurosci
Title: Necdin controls proliferation and apoptosis of embryonic neural stem cells in an oxygen tension-dependent manner.
Volume: 33
Issue: 25
Pages: 10362-73
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Publication
34433035 | J:330772
First Author: Li X
Year: 2021
Journal: Cell Rep
Title: Macrophage HIF-2α suppresses NLRP3 inflammasome activation and alleviates insulin resistance.
Volume: 36
Issue: 8
Pages: 109607
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Publication
32513733 | J:294116
First Author: Bhurke A
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: A hypoxia-induced Rab pathway regulates embryo implantation by controlled trafficking of secretory granules.
Volume: 117
Issue: 25
Pages: 14532-14542
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Publication
34593646 | J:311736
 
First Author: Yook JS
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Essential role of systemic iron mobilization and redistribution for adaptive thermogenesis through HIF2-α/hepcidin axis.
Volume: 118
Issue: 40
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Publication
29480820 | J:261174
First Author: Ghosh MC
Year: 2018
Journal: J Clin Invest
Title: Translational repression of HIF2α expression in mice with Chuvash polycythemia reverses polycythemia.
Volume: 128
Issue: 4
Pages: 1317-1325
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Publication
23395174 | J:198049
First Author: Anderson SA
Year: 2013
Journal: Cell Metab
Title: The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption.
Volume: 17
Issue: 2
Pages: 282-90
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Publication
23777768 | J:202286
First Author: Wilkinson N
Year: 2013
Journal: Blood
Title: IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2α mRNA translation.
Volume: 122
Issue: 9
Pages: 1658-68
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Publication
32019729 | J:317676
 
First Author: Hale AT
Year: 2020
Journal: Adv Biol Regul
Title: Modulation of sulfur assimilation metabolic toxicity overcomes anemia and hemochromatosis in mice.
Volume: 76
Pages: 100694
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Publication
17992257 | J:130780
First Author: Hickey MM
Year: 2007
Journal: J Clin Invest
Title: von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
Volume: 117
Issue: 12
Pages: 3879-89
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Publication
24347567 | J:206286
First Author: Yang S
Year: 2015
Journal: Ann Rheum Dis
Title: NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis.
Volume: 74
Issue: 3
Pages: 595-602
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Publication
20713899 | J:178586
First Author: Chen L
Year: 2010
Journal: Circulation
Title: Int6/eIF3e silencing promotes functional blood vessel outgrowth and enhances wound healing by upregulating hypoxia-induced factor 2alpha expression.
Volume: 122
Issue: 9
Pages: 910-9
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Publication
24947359 | J:230173
First Author: Choe SS
Year: 2014
Journal: Diabetes
Title: Macrophage HIF-2α ameliorates adipose tissue inflammation and insulin resistance in obesity.
Volume: 63
Issue: 10
Pages: 3359-71
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Publication
21856340 | J:180719
First Author: An HJ
Year: 2011
Journal: Biochim Biophys Acta
Title: The survival effect of mitochondrial Higd-1a is associated with suppression of cytochrome C release and prevention of caspase activation.
Volume: 1813
Issue: 12
Pages: 2088-98
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Publication
9398602 | J:44322
First Author: Ladoux A
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Cardiac expressions of HIF-1 alpha and HLF/EPAS, two basic loop helix/PAS domain transcription factors involved in adaptative responses to hypoxic stresses.
Volume: 240
Issue: 3
Pages: 552-6
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Publication
21742975 | J:179164
First Author: Vezys V
Year: 2011
Journal: J Immunol
Title: 4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection.
Volume: 187
Issue: 4
Pages: 1634-42
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Publication
23437279 | J:196069
First Author: Choi HJ
Year: 2013
Journal: PLoS One
Title: ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement.
Volume: 8
Issue: 2
Pages: e56949
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Publication
23897427 | J:205022
First Author: Sena JA
Year: 2013
Journal: Mol Cell Biol
Title: BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genes.
Volume: 33
Issue: 19
Pages: 3849-63
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Publication
25023702 | J:221254
First Author: Gómez-Maldonado L
Year: 2015
Journal: Oncogene
Title: EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination.
Volume: 34
Issue: 20
Pages: 2609-20
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Publication
31515405 | J:297000
 
First Author: Hu CJ
Year: 2019
Journal: Eur Respir J
Title: Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension.
Volume: 54
Issue: 6
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Publication
22407773 | J:310428
First Author: Oh H
Year: 2012
Journal: J Bone Miner Res
Title: Misexpression of Dickkopf-1 in endothelial cells, but not in chondrocytes or hypertrophic chondrocytes, causes defects in endochondral ossification.
Volume: 27
Issue: 6
Pages: 1335-44
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Publication
28232488 | J:318428
First Author: Yang X
Year: 2017
Journal: J Biol Chem
Title: The hypoxia-inducible factors HIF1α and HIF2α are dispensable for embryonic muscle development but essential for postnatal muscle regeneration.
Volume: 292
Issue: 14
Pages: 5981-5991
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Publication
26245371 | J:247431
First Author: Wu D
Year: 2015
Journal: Nature
Title: Structural integration in hypoxia-inducible factors.
Volume: 524
Issue: 7565
Pages: 303-8
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Publication
26398496 | J:236849
First Author: Gerl K
Year: 2015
Journal: Kidney Int
Title: Inducible glomerular erythropoietin production in the adult kidney.
Volume: 88
Issue: 6
Pages: 1345-1355
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Publication
30586708 | J:280004
First Author: Jiang X
Year: 2019
Journal: Circulation
Title: Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature.
Volume: 139
Issue: 4
Pages: 502-517
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Publication
38422022 | J:346095
First Author: Ma J
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment.
Volume: 121
Issue: 10
Pages: e2309957121
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Publication
22095691 | J:180600
First Author: Hirata M
Year: 2012
Journal: Hum Mol Genet
Title: C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.
Volume: 21
Issue: 5
Pages: 1111-23
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Publication
24076634 | J:208201
First Author: Doedens AL
Year: 2013
Journal: Nat Immunol
Title: Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen.
Volume: 14
Issue: 11
Pages: 1173-82
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Publication
33024109 | J:303356
First Author: Hsu TS
Year: 2020
Journal: Nat Commun
Title: HIF-2α is indispensable for regulatory T cell function.
Volume: 11
Issue: 1
Pages: 5005
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Publication
29049022 | J:250300
   
First Author: Cowburn AS
Year: 2017
Journal: Elife
Title: Cardiovascular adaptation to hypoxia and the role of peripheral resistance.
Volume: 6
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Publication
29339479 | J:257753
First Author: Devignes CS
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice.
Volume: 115
Issue: 5
Pages: E992-E1001
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Publication
16977322 | J:144666
First Author: Kim WY
Year: 2006
Journal: EMBO J
Title: Failure to prolyl hydroxylate hypoxia-inducible factor alpha phenocopies VHL inactivation in vivo.
Volume: 25
Issue: 19
Pages: 4650-62
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Publication
24282296 | J:205514
First Author: Anderson ER
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Intestinal HIF2α promotes tissue-iron accumulation in disorders of iron overload with anemia.
Volume: 110
Issue: 50
Pages: E4922-30
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Publication
23264599 | J:194598
First Author: Franke K
Year: 2013
Journal: Blood
Title: HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.
Volume: 121
Issue: 8
Pages: 1436-45
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Publication
20628150 | J:165868
First Author: Kapitsinou PP
Year: 2010
Journal: Blood
Title: Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia.
Volume: 116
Issue: 16
Pages: 3039-48
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Publication
22936665 | J:192921
First Author: Weigert A
Year: 2012
Journal: Blood
Title: HIF-1α is a negative regulator of plasmacytoid DC development in vitro and in vivo.
Volume: 120
Issue: 15
Pages: 3001-6
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Publication
15689487 | J:99217
First Author: Cowden Dahl KD
Year: 2005
Journal: Mol Biol Cell
Title: Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression.
Volume: 16
Issue: 4
Pages: 1901-12
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Publication
21814490 | J:175600
First Author: Zhang H
Year: 2011
Journal: PLoS Biol
Title: Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation.
Volume: 9
Issue: 7
Pages: e1001112
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Publication
25855602 | J:222624
First Author: Krock BL
Year: 2015
Journal: Blood
Title: The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability.
Volume: 125
Issue: 21
Pages: 3263-72
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Publication
20881124 | J:164878
First Author: Chen G
Year: 2010
Journal: J Neurosci
Title: CREB binding protein is required for both short-term and long-term memory formation.
Volume: 30
Issue: 39
Pages: 13066-77
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Publication
24999590 | J:217942
First Author: Wong WJ
Year: 2015
Journal: J Invest Dermatol
Title: Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function.
Volume: 135
Issue: 2
Pages: 454-461
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Publication
29190746 | J:252629
First Author: Scott CH
Year: 2017
Journal: PLoS One
Title: Hepatic Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) regulates metabolism in mice.
Volume: 12
Issue: 11
Pages: e0186543
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Publication
26642852 | J:229015
First Author: Vukovic M
Year: 2015
Journal: J Exp Med
Title: Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance.
Volume: 212
Issue: 13
Pages: 2223-34
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Publication
33914705 | J:308502
 
First Author: Singhal R
Year: 2021
Journal: J Clin Invest
Title: HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.
Volume: 131
Issue: 12
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Publication
27546461 | J:251873
First Author: Xue X
Year: 2016
Journal: Cell Metab
Title: Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis.
Volume: 24
Issue: 3
Pages: 447-461
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Publication
27798602 | J:243079
First Author: Tyrakis PA
Year: 2016
Journal: Nature
Title: S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate.
Volume: 540
Issue: 7632
Pages: 236-241
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Publication
29136509 | J:248840
First Author: Palazon A
Year: 2017
Journal: Cancer Cell
Title: An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression.
Volume: 32
Issue: 5
Pages: 669-683.e5
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Publication
25015343 | J:227457
First Author: Wong MS
Year: 2014
Journal: Circulation
Title: Vitamin D promotes vascular regeneration.
Volume: 130
Issue: 12
Pages: 976-86
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Publication
31695081 | J:287297
First Author: Samardzija M
Year: 2019
Journal: Sci Rep
Title: Hif1a and Hif2a can be safely inactivated in cone photoreceptors.
Volume: 9
Issue: 1
Pages: 16121
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Publication
24101470 | J:201979
First Author: Cowburn AS
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: HIF isoforms in the skin differentially regulate systemic arterial pressure.
Volume: 110
Issue: 43
Pages: 17570-5
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Publication
29036334 | J:254388
First Author: Wang J
Year: 2017
Journal: Nucleic Acids Res
Title: Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity.
Volume: 45
Issue: 22
Pages: 12700-12714
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Publication
26976644 | J:236191
First Author: Kapitsinou PP
Year: 2016
Journal: Mol Cell Biol
Title: The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice.
Volume: 36
Issue: 10
Pages: 1584-94
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24789906 | J:212930
First Author: Kapitsinou PP
Year: 2014
Journal: J Clin Invest
Title: Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury.
Volume: 124
Issue: 6
Pages: 2396-409
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Publication
24497508 | J:206831
First Author: Ahn GO
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8.
Volume: 111
Issue: 7
Pages: 2698-703
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Publication
34556788 | J:312362
First Author: Todd VM
Year: 2021
Journal: Commun Biol
Title: Hypoxia inducible factor signaling in breast tumors controls spontaneous tumor dissemination in a site-specific manner.
Volume: 4
Issue: 1
Pages: 1122
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31436357 | J:290088
First Author: Susen RM
Year: 2019
Journal: Mol Carcinog
Title: Macrophage HIF-2α regulates tumor-suppressive Spint1 in the tumor microenvironment.
Volume: 58
Issue: 11
Pages: 2127-2138
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Publication
27432976 | J:234394
First Author: Cowburn AS
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: HIF2α-arginase axis is essential for the development of pulmonary hypertension.
Volume: 113
Issue: 31
Pages: 8801-6
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Publication
25377876 | J:249475
First Author: Michailidou Z
Year: 2015
Journal: Diabetes
Title: Adipocyte pseudohypoxia suppresses lipolysis and facilitates benign adipose tissue expansion.
Volume: 64
Issue: 3
Pages: 733-45
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Publication
35192456 | J:321651
   
First Author: Ajouaou Y
Year: 2022
Journal: Elife
Title: The oxygen sensor prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells.
Volume: 11
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Publication
27271565 | J:297699
First Author: Fecher RA
Year: 2016
Journal: J Immunol
Title: Inverse Correlation between IL-10 and HIF-1α in Macrophages Infected with Histoplasma capsulatum.
Volume: 197
Issue: 2
Pages: 565-79
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25023703 | J:221253
First Author: Pritchett TL
Year: 2015
Journal: Oncogene
Title: Conditional inactivation of the mouse von Hippel-Lindau tumor suppressor gene results in wide-spread hyperplastic, inflammatory and fibrotic lesions in the kidney.
Volume: 34
Issue: 20
Pages: 2631-9
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Publication
29967068 | J:263648
 
First Author: Kim YE
Year: 2018
Journal: Dis Model Mech
Title: HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice.
Volume: 11
Issue: 7
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29666476 | J:269311
First Author: Barben M
Year: 2018
Journal: Cell Death Differ
Title: Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress.
Volume: 25
Issue: 12
Pages: 2071-2085
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31403471 | J:293718
First Author: Rattner A
Year: 2019
Journal: J Clin Invest
Title: Roles of HIFs and VEGF in angiogenesis in the retina and brain.
Volume: 129
Issue: 9
Pages: 3807-3820
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23093773 | J:194014
First Author: Kurihara T
Year: 2012
Journal: J Clin Invest
Title: Targeted deletion of Vegfa in adult mice induces vision loss.
Volume: 122
Issue: 11
Pages: 4213-7
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35532553 | J:332040
 
First Author: Han J
Year: 2022
Journal: J Exp Med
Title: Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity.
Volume: 219
Issue: 6
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29983349 | J:272671
 
First Author: Kiers D
Year: 2018
Journal: EBioMedicine
Title: Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation.
Volume: 33
Pages: 144-156
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35672324 | J:327519
First Author: Han JS
Year: 2022
Journal: Nat Commun
Title: Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes.
Volume: 13
Issue: 1
Pages: 3268
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12832481 | J:84384
First Author: Park SK
Year: 2003
Journal: Mol Cell Biol
Title: Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha.
Volume: 23
Issue: 14
Pages: 4959-71
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22869907 | J:333641
First Author: Roda JM
Year: 2012
Journal: J Immunol
Title: Stabilization of HIF-2α induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth in a murine melanoma model.
Volume: 189
Issue: 6
Pages: 3168-77
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27001147 | J:240855
 
First Author: Li L
Year: 2016
Journal: Neurobiol Dis
Title: Neuronal deficiency of HIF prolyl 4-hydroxylase 2 in mice improves ischemic stroke recovery in an HIF dependent manner.
Volume: 91
Pages: 221-35
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35724581 | J:328269
 
First Author: Christoph M
Year: 2022
Journal: Mol Immunol
Title: Myeloid PHD2 deficiency accelerates neointima formation via Hif-1α.
Volume: 149
Pages: 48-58
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22081627 | J:178824
First Author: Riddle RC
Year: 2011
Journal: J Biol Chem
Title: Hypoxia-inducible factor-1α protein negatively regulates load-induced bone formation.
Volume: 286
Issue: 52
Pages: 44449-56
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22684009 | J:186999
First Author: Pourvali K
Year: 2012
Journal: FEBS Lett
Title: Basal expression of copper transporter 1 in intestinal epithelial cells is regulated by hypoxia-inducible factor 2α.
Volume: 586
Issue: 16
Pages: 2423-7
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29483579 | J:336384
First Author: Koeppen M
Year: 2018
Journal: Nat Commun
Title: Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury.
Volume: 9
Issue: 1
Pages: 816
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25018103 | J:214629
First Author: Yuen TJ
Year: 2014
Journal: Cell
Title: Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis.
Volume: 158
Issue: 2
Pages: 383-396
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28760743 | J:253318
First Author: Maier A
Year: 2017
Journal: FASEB J
Title: Hypoxia-inducible protein 2 Hig2/Hilpda mediates neutral lipid accumulation in macrophages and contributes to atherosclerosis in apolipoprotein E-deficient mice.
Volume: 31
Issue: 11
Pages: 4971-4984
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19528226 | J:151523
First Author: Rankin EB
Year: 2009
Journal: Mol Cell Biol
Title: Hypoxia-inducible factor 2 regulates hepatic lipid metabolism.
Volume: 29
Issue: 16
Pages: 4527-38
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Publication
28112274 | J:275118
 
First Author: Gardner PJ
Year: 2017
Journal: Sci Rep
Title: Hypoxia inducible factors are dispensable for myeloid cell migration into the inflamed mouse eye.
Volume: 7
Pages: 40830
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20194441 | J:263290
First Author: Takeda N
Year: 2010
Journal: Genes Dev
Title: Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis.
Volume: 24
Issue: 5
Pages: 491-501
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Publication
24326162 | J:315910
First Author: Lin Q
Year: 2013
Journal: J Am Heart Assoc
Title: Activation of hypoxia-inducible factor-2 in adipocytes results in pathological cardiac hypertrophy.
Volume: 2
Issue: 6
Pages: e000548
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Publication
22930750 | J:214713
First Author: Aro E
Year: 2012
Journal: J Biol Chem
Title: Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes.
Volume: 287
Issue: 44
Pages: 37134-44
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