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Search results 1 to 100 out of 314 for Nnt

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0.043s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Allouche J
Year: 2021
Journal: Cell
Title: NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism.
Volume: 184
Issue: 16
Pages: 4268-4283.e20
Publication
First Author: Meimaridou E
Year: 2012
Journal: Nat Genet
Title: Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency.
Volume: 44
Issue: 7
Pages: 740-2
Publication
First Author: Meimaridou E
Year: 2018
Journal: J Endocrinol
Title: NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice.
Volume: 236
Issue: 1
Pages: 13-28
Publication  
First Author: Williams JL
Year: 2020
Journal: Life Sci Alliance
Title: Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not.
Volume: 3
Issue: 4
Publication    
First Author: Rawle DJ
Year: 2022
Journal: Elife
Title: Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies.
Volume: 11
Publication
First Author: Freeman HC
Year: 2006
Journal: Diabetes
Title: Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice.
Volume: 55
Issue: 7
Pages: 2153-6
Publication
First Author: Freeman H
Year: 2006
Journal: Cell Metab
Title: Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion.
Volume: 3
Issue: 1
Pages: 35-45
Publication
First Author: Nickel AG
Year: 2015
Journal: Cell Metab
Title: Reversal of Mitochondrial Transhydrogenase Causes Oxidative Stress in Heart Failure.
Volume: 22
Issue: 3
Pages: 472-84
Publication
First Author: Chortis V
Year: 2018
Journal: Endocrinology
Title: Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma.
Volume: 159
Issue: 8
Pages: 2836-2849
Publication
First Author: Wong N
Year: 2010
Journal: Endocrinology
Title: The deletion variant of nicotinamide nucleotide transhydrogenase (Nnt) does not affect insulin secretion or glucose tolerance.
Volume: 151
Issue: 1
Pages: 96-102
Publication  
First Author: Bicego R
Year: 2020
Journal: Arch Biochem Biophys
Title: Undesirable effects of chemical inhibitors of NAD(P)+ transhydrogenase on mitochondrial respiratory function.
Volume: 692
Pages: 108535
Publication  
First Author: Ronchi JA
Year: 2013
Journal: Free Radic Biol Med
Title: A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities.
Volume: 63
Pages: 446-56
Publication
First Author: Ronchi JA
Year: 2016
Journal: J Biol Chem
Title: The Contribution of Nicotinamide Nucleotide Transhydrogenase to Peroxide Detoxification Is Dependent on the Respiratory State and Counterbalanced by Other Sources of NADPH in Liver Mitochondria.
Volume: 291
Issue: 38
Pages: 20173-87
Publication
First Author: Ripoll VM
Year: 2012
Journal: FASEB J
Title: Nicotinamide nucleotide transhydrogenase (NNT) acts as a novel modulator of macrophage inflammatory responses.
Volume: 26
Issue: 8
Pages: 3550-62
Publication
First Author: Francisco A
Year: 2018
Journal: J Neurochem
Title: Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet.
Volume: 147
Issue: 5
Pages: 663-677
Publication
First Author: Fisher-Wellman KH
Year: 2015
Journal: Biochem J
Title: Pyruvate dehydrogenase complex and nicotinamide nucleotide transhydrogenase constitute an energy-consuming redox circuit.
Volume: 467
Issue: 2
Pages: 271-80
Publication
First Author: Vozenilek AE
Year: 2018
Journal: J Vasc Res
Title: Absence of Nicotinamide Nucleotide Transhydrogenase in C57BL/6J Mice Exacerbates Experimental Atherosclerosis.
Volume: 55
Issue: 2
Pages: 98-110
Publication
First Author: Aston-Mourney K
Year: 2007
Journal: Diabetologia
Title: Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes.
Volume: 50
Issue: 12
Pages: 2476-85
Publication  
First Author: Navarro CDC
Year: 2017
Journal: Free Radic Biol Med
Title: Redox imbalance due to the loss of mitochondrial NAD(P)-transhydrogenase markedly aggravates high fat diet-induced fatty liver disease in mice.
Volume: 113
Pages: 190-202
Publication
First Author: Navarro SJ
Year: 2012
Journal: G3 (Bethesda)
Title: The C57BL/6J Mouse Strain Background Modifies the Effect of a Mutation in Bcl2l2.
Volume: 2
Issue: 1
Pages: 99-102
Publication
First Author: Anderson AA
Year: 2009
Journal: Pathogenetics
Title: Pancreatic islet expression profiling in diabetes-prone C57BLKS/J mice reveals transcriptional differences contributed by DBA loci, including Plagl1 and Nnt.
Volume: 2
Issue: 1
Pages: 1
Publication
First Author: Wagner M
Year: 2020
Journal: Basic Res Cardiol
Title: Selective NADH communication from α-ketoglutarate dehydrogenase to mitochondrial transhydrogenase prevents reactive oxygen species formation under reducing conditions in the heart.
Volume: 115
Issue: 5
Pages: 53
Publication  
First Author: Ward NP
Year: 2020
Journal: J Exp Med
Title: Nicotinamide nucleotide transhydrogenase regulates mitochondrial metabolism in NSCLC through maintenance of Fe-S protein function.
Volume: 217
Issue: 6
Publication
First Author: Salerno AG
Year: 2019
Journal: Biochem J
Title: Lack of mitochondrial NADP(H)-transhydrogenase expression in macrophages exacerbates atherosclerosis in hypercholesterolemic mice.
Volume: 476
Issue: 24
Pages: 3769-3789
Publication
First Author: Kim A
Year: 2010
Journal: Mamm Genome
Title: Genetic modifier of mitochondrial superoxide dismutase-deficient mice delays heart failure and prolongs survival.
Volume: 21
Issue: 11-12
Pages: 534-42
Publication
First Author: Parker N
Year: 2009
Journal: Biochim Biophys Acta
Title: Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.
Volume: 1787
Issue: 12
Pages: 1451-7
Author
Author
Publication
First Author: Son MJ
Year: 2016
Journal: Stem Cells
Title: Restoration of Mitochondrial NAD+ Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells.
Volume: 34
Issue: 12
Pages: 2840-2851
Publication
First Author: Huang TT
Year: 2006
Journal: Hum Mol Genet
Title: Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase.
Volume: 15
Issue: 7
Pages: 1187-94
Publication
First Author: Toye AA
Year: 2005
Journal: Diabetologia
Title: A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.
Volume: 48
Issue: 4
Pages: 675-86
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Arkblad EL
Year: 1996
Journal: Biochim Biophys Acta
Title: The cDNA sequence of proton-pumping nicotinamide nucleotide transhydrogenase from man and mouse.
Volume: 1273
Issue: 3
Pages: 203-5
Publication
First Author: Ulmasov B
Year: 2013
Journal: Am J Pathol
Title: Differences in the degree of cerulein-induced chronic pancreatitis in C57BL/6 mouse substrains lead to new insights in identification of potential risk factors in the development of chronic pancreatitis.
Volume: 183
Issue: 3
Pages: 692-708
Publication
First Author: Arkblad EL
Year: 1997
Journal: Mamm Genome
Title: Mapping of the rat and mouse nicotinamide nucleotide transhydrogenase gene.
Volume: 8
Issue: 9
Pages: 703
Publication
First Author: Smith CD
Year: 2020
Journal: J Biol Chem
Title: Flux through mitochondrial redox circuits linked to nicotinamide nucleotide transhydrogenase generates counterbalance changes in energy expenditure.
Volume: 295
Issue: 48
Pages: 16207-16216
GXD Expression      
Probe: MGI:3522180
Assay Type: RT-PCR
Annotation Date: 2005-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716822
Stage: TS22
Assay Id: MGI:3522257
Age: embryonic day 14.5
Specimen Label: Wild type
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3522180
Assay Type: RT-PCR
Annotation Date: 2005-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716822
Stage: TS22
Assay Id: MGI:3522257
Age: embryonic day 14.5
Specimen Label: Brn3b -/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Image: EB39; Specimen B104
Specimen Label: EB39; Specimen B104
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760622
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Image: EB39; Specimen B104
Specimen Label: EB39; Specimen B104
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666522
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619822
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754922
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Note: Expression was not detected in the corpus striatum (lateral ganglionic eminence).
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Image: EB39; Specimen B104
Specimen Label: EB39; Specimen B104
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3276322
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Note: Expression was not detected in the face/soft tissues.
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1783822
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1665922
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1706822
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_13
Specimen Label: euxassay_007280_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_14
Specimen Label: euxassay_007280_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_15
Specimen Label: euxassay_007280_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_16
Specimen Label: euxassay_007280_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_17
Specimen Label: euxassay_007280_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_18
Specimen Label: euxassay_007280_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_19
Specimen Label: euxassay_007280_19
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_20
Specimen Label: euxassay_007280_20
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_21
Specimen Label: euxassay_007280_21
Detected: true
Specimen Num: 21
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1674822
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1670622
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738222
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1654222
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310596
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1777922
Stage: TS22
Assay Id: MGI:5423919
Age: embryonic day 14.5
Specimen Label: EB39; Specimen B104
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_02
Specimen Label: euxassay_007280_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_03
Specimen Label: euxassay_007280_03
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_04
Specimen Label: euxassay_007280_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_05
Specimen Label: euxassay_007280_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:498880
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826738
Age: embryonic day 14.5
Image: euxassay_007280_06
Specimen Label: euxassay_007280_06
Detected: true
Specimen Num: 6