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Search results 301 to 400 out of 1143 for Aim2

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Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Casano FJ
Year: 1994
Journal: Genomics
Title: The structure and complete nucleotide sequence of the murine gene encoding interleukin-1 beta converting enzyme (ICE).
Volume: 20
Issue: 3
Pages: 474-81
Publication
First Author: Broz P
Year: 2010
Journal: Cell Host Microbe
Title: Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing.
Volume: 8
Issue: 6
Pages: 471-83
Publication
First Author: Hersh D
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1.
Volume: 96
Issue: 5
Pages: 2396-401
Publication
First Author: Kumar S
Year: 1995
Journal: Trends Biochem Sci
Title: ICE-like proteases in apoptosis.
Volume: 20
Issue: 5
Pages: 198-202
Publication
First Author: Friedlander RM
Year: 1997
Journal: J Exp Med
Title: Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury.
Volume: 185
Issue: 5
Pages: 933-40
Publication
First Author: Andreassen OA
Year: 2000
Journal: J Neurochem
Title: Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant.
Volume: 75
Issue: 2
Pages: 847-52
Publication
First Author: Klevenyi P
Year: 1999
Journal: Neuroreport
Title: Transgenic mice expressing a dominant negative mutant interleukin-1beta converting enzyme show resistance to MPTP neurotoxicity.
Volume: 10
Issue: 3
Pages: 635-8
Publication
First Author: Liu T
Year: 2014
Journal: Cell Rep
Title: Single-cell imaging of caspase-1 dynamics reveals an all-or-none inflammasome signaling response.
Volume: 8
Issue: 4
Pages: 974-82
Publication
First Author: Kudo E
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Low ambient humidity impairs barrier function and innate resistance against influenza infection.
Volume: 116
Issue: 22
Pages: 10905-10910
Publication
First Author: Ona VO
Year: 1999
Journal: Nature
Title: Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease.
Volume: 399
Issue: 6733
Pages: 263-7
Publication
First Author: Itoi H
Year: 2001
Journal: Blood
Title: Fas ligand-induced caspase-1-dependent accumulation of interleukin-18 in mice with acute graft-versus-host disease.
Volume: 98
Issue: 1
Pages: 235-7
Publication
First Author: Barber G
Year: 2020
Journal: Cancer Immunol Immunother
Title: Characterizing caspase-1 involvement during esophageal disease progression.
Volume: 69
Issue: 12
Pages: 2635-2649
Publication
First Author: Devi S
Year: 2023
Journal: Cell Rep
Title: CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout.
Volume: 42
Issue: 3
Pages: 112265
Publication
First Author: Kuida K
Year: 1995
Journal: Science
Title: Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme.
Volume: 267
Issue: 5206
Pages: 2000-3
Publication
First Author: Wangdi T
Year: 2010
Journal: Infect Immun
Title: In vivo discrimination of type 3 secretion system-positive and -negative Pseudomonas aeruginosa via a caspase-1-dependent pathway.
Volume: 78
Issue: 11
Pages: 4744-53
Publication
First Author: Gu Y
Year: 1997
Journal: Science
Title: Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme.
Volume: 275
Issue: 5297
Pages: 206-9
Publication
First Author: Glennon EKK
Year: 2018
Journal: Sci Rep
Title: Elevated plasma abscisic acid is associated with asymptomatic falciparum malaria and with IgG-/caspase-1-dependent immunity in Plasmodium yoelii-infected mice.
Volume: 8
Issue: 1
Pages: 8896
Publication
First Author: Ko DC
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death.
Volume: 109
Issue: 35
Pages: E2343-52
Publication
First Author: Thakur A
Year: 2004
Journal: Curr Eye Res
Title: Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice.
Volume: 29
Issue: 4-5
Pages: 225-33
Publication  
First Author: Jessop F
Year: 2017
Journal: Toxicol Appl Pharmacol
Title: Phagolysosome acidification is required for silica and engineered nanoparticle-induced lysosome membrane permeabilization and resultant NLRP3 inflammasome activity.
Volume: 318
Pages: 58-68
Publication
First Author: Wang W
Year: 2005
Journal: Am J Physiol Renal Physiol
Title: Endotoxemic acute renal failure is attenuated in caspase-1-deficient mice.
Volume: 288
Issue: 5
Pages: F997-1004
Publication
First Author: Siegmund B
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation.
Volume: 98
Issue: 23
Pages: 13249-54
Publication
First Author: Lopez-Pastrana J
Year: 2015
Journal: J Biol Chem
Title: Inhibition of Caspase-1 Activation in Endothelial Cells Improves Angiogenesis: A NOVEL THERAPEUTIC POTENTIAL FOR ISCHEMIA.
Volume: 290
Issue: 28
Pages: 17485-94
Publication
First Author: Stewart MK
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Regulation of phenotypic heterogeneity permits Salmonella evasion of the host caspase-1 inflammatory response.
Volume: 108
Issue: 51
Pages: 20742-7
Publication
First Author: Fantuzzi G
Year: 1999
Journal: J Clin Invest
Title: IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor.
Volume: 104
Issue: 6
Pages: 761-7
Publication
First Author: Breitbach K
Year: 2009
Journal: Infect Immun
Title: Caspase-1 mediates resistance in murine melioidosis.
Volume: 77
Issue: 4
Pages: 1589-95
Publication
First Author: Gao P
Year: 2014
Journal: Biochim Biophys Acta
Title: Thioredoxin-interacting protein mediates NALP3 inflammasome activation in podocytes during diabetic nephropathy.
Volume: 1843
Issue: 11
Pages: 2448-60
Publication
First Author: Liu N
Year: 2009
Journal: Infect Immun
Title: The caspase 1 inflammasome is not required for control of murine Lyme borreliosis.
Volume: 77
Issue: 8
Pages: 3320-7
Publication
First Author: Dixon LJ
Year: 2013
Journal: PLoS One
Title: Caspase-1 as a central regulator of high fat diet-induced non-alcoholic steatohepatitis.
Volume: 8
Issue: 2
Pages: e56100
Publication
First Author: Bergsbaken T
Year: 2011
Journal: J Immunol
Title: Coordinated host responses during pyroptosis: caspase-1-dependent lysosome exocytosis and inflammatory cytokine maturation.
Volume: 187
Issue: 5
Pages: 2748-54
Publication
First Author: Niu Z
Year: 2017
Journal: Nat Commun
Title: Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs.
Volume: 8
Issue: 1
Pages: 766
Publication
First Author: Tsuji NM
Year: 2004
Journal: Int Immunol
Title: Roles of caspase-1 in Listeria infection in mice.
Volume: 16
Issue: 2
Pages: 335-43
Publication  
First Author: Devant P
Year: 2021
Journal: Sci Immunol
Title: Evolution-inspired redesign of the LPS receptor caspase-4 into an interleukin-1β converting enzyme.
Volume: 6
Issue: 62
Publication
First Author: van Diepen JA
Year: 2013
Journal: J Lipid Res
Title: Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion.
Volume: 54
Issue: 2
Pages: 448-56
Publication
First Author: Dixon LJ
Year: 2012
Journal: Lab Invest
Title: Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis.
Volume: 92
Issue: 5
Pages: 713-23
Publication
First Author: Hopf V
Year: 2014
Journal: Infect Immun
Title: BPSS1504, a cluster 1 type VI secretion gene, is involved in intracellular survival and virulence of Burkholderia pseudomallei.
Volume: 82
Issue: 5
Pages: 2006-15
Publication
First Author: Periasamy S
Year: 2016
Journal: PLoS Pathog
Title: An Immature Myeloid/Myeloid-Suppressor Cell Response Associated with Necrotizing Inflammation Mediates Lethal Pulmonary Tularemia.
Volume: 12
Issue: 3
Pages: e1005517
Publication
First Author: Li P
Year: 1995
Journal: Cell
Title: Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock.
Volume: 80
Issue: 3
Pages: 401-11
Publication
First Author: van der Velden AW
Year: 2003
Journal: J Immunol
Title: Salmonella rapidly kill dendritic cells via a caspase-1-dependent mechanism.
Volume: 171
Issue: 12
Pages: 6742-9
Publication
First Author: Rowe SJ
Year: 2002
Journal: J Immunol
Title: Caspase-1-deficient mice have delayed neutrophil apoptosis and a prolonged inflammatory response to lipopolysaccharide-induced acute lung injury.
Volume: 169
Issue: 11
Pages: 6401-7
Publication
First Author: Jehl SP
Year: 2011
Journal: Infect Immun
Title: Antigen-specific CD8(+) T cells fail to respond to Shigella flexneri.
Volume: 79
Issue: 5
Pages: 2021-30
Publication
First Author: Antonopoulos C
Year: 2001
Journal: J Immunol
Title: Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitization in mice.
Volume: 166
Issue: 6
Pages: 3672-7
Publication
First Author: Liu XH
Year: 1999
Journal: J Cereb Blood Flow Metab
Title: Mice deficient in interleukin-1 converting enzyme are resistant to neonatal hypoxic-ischemic brain damage.
Volume: 19
Issue: 10
Pages: 1099-108
Publication
First Author: Mastronardi C
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Caspase 1 deficiency reduces inflammation-induced brain transcription.
Volume: 104
Issue: 17
Pages: 7205-10
Publication
First Author: Sundquist M
Year: 2005
Journal: J Immunol
Title: TNF-alpha-dependent and -independent maturation of dendritic cells and recruited CD11c(int)CD11b+ Cells during oral Salmonella infection.
Volume: 175
Issue: 5
Pages: 3287-98
Publication
First Author: Epperly M
Year: 2013
Journal: In Vivo
Title: Increased longevity of hematopoiesis in continuous marrow cultures and radiation resistance of marrow stromal and hematopoietic progenitor cells from caspase-1 homozygous recombinant-negative (knockout) mice.
Volume: 27
Issue: 4
Pages: 419-30
Publication
First Author: Liège S
Year: 2000
Journal: Neuroimmunomodulation
Title: Activation of the hypothalamic-pituitary-adrenal axis in IL-1 beta-converting enzyme-deficient mice.
Volume: 7
Issue: 4
Pages: 189-94
Publication
First Author: Schott WH
Year: 2004
Journal: Diabetes
Title: Caspase-1 is not required for type 1 diabetes in the NOD mouse.
Volume: 53
Issue: 1
Pages: 99-104
Publication
First Author: Yao JH
Year: 1999
Journal: Am J Physiol
Title: Mice deficient in interleukin-1beta converting enzyme resist anorexia induced by central lipopolysaccharide.
Volume: 277
Issue: 5 Pt 2
Pages: R1435-43
Publication
First Author: Yang GY
Year: 1999
Journal: J Cereb Blood Flow Metab
Title: Expression of tumor necrosis factor-alpha and intercellular adhesion molecule-1 after focal cerebral ischemia in interleukin-1beta converting enzyme deficient mice.
Volume: 19
Issue: 10
Pages: 1109-17
Publication
First Author: Li P
Year: 1997
Journal: J Cell Biochem
Title: Characterization of mice deficient in interleukin-1 beta converting enzyme.
Volume: 64
Issue: 1
Pages: 27-32
Publication
First Author: Cheng W
Year: 2008
Journal: Infect Immun
Title: Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection.
Volume: 76
Issue: 2
Pages: 515-22
Publication
First Author: de Bilbao F
Year: 2000
Journal: Neuroscience
Title: In vivo study of motoneuron death induced by nerve injury in mice deficient in the caspase 1/ interleukin-1 beta-converting enzyme.
Volume: 98
Issue: 3
Pages: 573-83
Publication
First Author: Murphey ED
Year: 2011
Journal: J Immunol
Title: Cecal ligation and puncture-induced impairment of innate immune function does not occur in the absence of caspase-1.
Volume: 187
Issue: 2
Pages: 905-10
Publication
First Author: Chen Y
Year: 1996
Journal: EMBO J
Title: A bacterial invasin induces macrophage apoptosis by binding directly to ICE.
Volume: 15
Issue: 15
Pages: 3853-60
Publication
First Author: Samanta H
Year: 1986
Journal: J Biol Chem
Title: Interferons as gene activators. Cloning of the 5' terminus and the control segment of an interferon activated gene.
Volume: 261
Issue: 25
Pages: 11849-58
Publication
First Author: Yuan J
Year: 1993
Journal: Cell
Title: The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme.
Volume: 75
Issue: 4
Pages: 641-52
Publication
First Author: Miura M
Year: 1993
Journal: Cell
Title: Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3.
Volume: 75
Issue: 4
Pages: 653-60
Publication
First Author: Miller BE
Year: 1995
Journal: J Immunol
Title: Inhibition of mature IL-1 beta production in murine macrophages and a murine model of inflammation by WIN 67694, an inhibitor of IL-1 beta converting enzyme.
Volume: 154
Issue: 3
Pages: 1331-8
Publication
First Author: Kumar S
Year: 1995
Journal: FEBS Lett
Title: Role of multiple cellular proteases in the execution of programmed cell death.
Volume: 375
Issue: 3
Pages: 169-73
Publication
First Author: Sarin A
Year: 1997
Journal: Immunity
Title: Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases.
Volume: 6
Issue: 2
Pages: 209-15
Publication
First Author: Yao J
Year: 1997
Journal: Brain Res Mol Brain Res
Title: Induction of interleukin-1 beta-converting enzyme (ICE) in murine microglia by lipopolysaccharide.
Volume: 51
Issue: 1-2
Pages: 170-8
Publication
First Author: van Molle W
Year: 1999
Journal: FEBS Lett
Title: Caspase-1 is not involved in experimental hepatitis in mouse.
Volume: 445
Issue: 1
Pages: 115-8
Publication
First Author: Whyte M
Year: 1996
Journal: Trends Cell Biol
Title: A link between cell-surface receptors and ICE proteases.
Volume: 6
Issue: 11
Pages: 418
Publication
First Author: Kahlenberg JM
Year: 2005
Journal: J Immunol
Title: Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis.
Volume: 175
Issue: 11
Pages: 7611-22
Publication
First Author: Feldmeyer L
Year: 2007
Journal: Curr Biol
Title: The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes.
Volume: 17
Issue: 13
Pages: 1140-5
Publication
First Author: Merkle S
Year: 2007
Journal: Circ Res
Title: A role for caspase-1 in heart failure.
Volume: 100
Issue: 5
Pages: 645-53
Publication
First Author: Fernandes-Alnemri T
Year: 2007
Journal: Cell Death Differ
Title: The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation.
Volume: 14
Issue: 9
Pages: 1590-604
Publication
First Author: Timmer AM
Year: 2009
Journal: J Biol Chem
Title: Streptolysin O promotes group A Streptococcus immune evasion by accelerated macrophage apoptosis.
Volume: 284
Issue: 2
Pages: 862-71
Publication
First Author: Bulau AM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses.
Volume: 111
Issue: 7
Pages: 2650-5
Publication
First Author: Yu J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy.
Volume: 111
Issue: 43
Pages: 15514-9
Publication
First Author: Rothmeier AS
Year: 2015
Journal: J Clin Invest
Title: Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles.
Volume: 125
Issue: 4
Pages: 1471-84
Publication
First Author: Boucher D
Year: 2018
Journal: J Exp Med
Title: Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.
Volume: 215
Issue: 3
Pages: 827-840
Publication
First Author: Monteith AJ
Year: 2018
Journal: J Immunol
Title: mTORC2 Activity Disrupts Lysosome Acidification in Systemic Lupus Erythematosus by Impairing Caspase-1 Cleavage of Rab39a.
Volume: 201
Issue: 2
Pages: 371-382
Publication  
First Author: Towers AE
Year: 2019
Journal: Brain Behav Immun
Title: Handling stress impairs learning through a mechanism involving caspase-1 activation and adenosine signaling.
Volume: 80
Pages: 763-776
Publication  
First Author: Ramesova A
Year: 2021
Journal: Int J Mol Sci
Title: Caspase-1 Inhibition Impacts the Formation of Chondrogenic Nodules, and the Expression of Markers Related to Osteogenic Differentiation and Lipid Metabolism.
Volume: 22
Issue: 17
Publication  
First Author: Luo Y
Year: 2022
Journal: EBioMedicine
Title: Akkermansia muciniphila prevents cold-related atrial fibrillation in rats by modulation of TMAO induced cardiac pyroptosis.
Volume: 82
Pages: 104087
GXD Expression      
Probe: MGI:1329385
Assay Type: RT-PCR
Annotation Date: 1999-02-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:1329454
Age: embryonic day 4.0
Specimen Label: caspase-1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:2668229
Assay Type: RT-PCR
Annotation Date: 2003-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737320
Stage: TS20
Assay Id: MGI:2668236
Age: embryonic day 12.0
Specimen Label: E12
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2668229
Assay Type: RT-PCR
Annotation Date: 2003-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737323
Stage: TS23
Assay Id: MGI:2668236
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2668229
Assay Type: RT-PCR
Annotation Date: 2003-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737327
Stage: TS27
Assay Id: MGI:2668236
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 4