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Search results 101 to 114 out of 114 for Prdm10

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0.018s
Type Details Score
Protein Domain
Type: Domain
Description: This is a zinc knuckle motif found in PRDM4 (Schwann cell factor 1, SC-1), a member of the PR protein family. PRDM4 is a transcriptional regulator that has been implied in transduction of nerve growth factor signals via the p75 neurotrophin receptor and in cell growth arrest. The short motif is also present in several other PR proteins including human PRDM6 (PRISM), PRDM7, PRDM9 (meisetz), PRDM10 (tristanin), PRDM11, and PRDM15. The conservation of cysteine and histidine residues suggested that this 20 amino acid motif binds zinc, hence the name 'PR zinc knuckle' to distinguish it from the longer (30 amino acid) C2H2-like zinc fingers that are located C-terminally of the PR domain. The PR zinc knuckle fold is similar to that of Gag-knuckles (a β-hairpin providing two zinc ligands followed by a short helix or a loop providing the other two zinc ligands) and zinc ribbons (two β-hairpins, each providing two zinc ligands) [].
Protein
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 803  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1184  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1135  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1172  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1115  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 796  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 743  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 796  
Fragment?: false
Publication
First Author: Wu H
Year: 2013
Journal: Cell Rep
Title: Molecular basis for the regulation of the H3K4 methyltransferase activity of PRDM9.
Volume: 5
Issue: 1
Pages: 13-20
Publication  
First Author: Casamassimi A
Year: 2020
Journal: Int J Mol Sci
Title: Multifaceted Role of PRDM Proteins in Human Cancer.
Volume: 21
Issue: 7