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Search results 1 to 100 out of 260 for Eya3

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0.052s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Domain
Type: Family
Description: Members of the eye absent (EYA) family were originally characterised in fly eye development. EYA proteins are both transcriptional activators and tyrosine phosphatases [, ], and have been shown to dephosphorylate H2AX, promoting repair and cell survival in the response to DNA damage []. EYA proteins (EYA1-4) are normally expressed early in development [, ]. Their phosphatase activity regulates Six1-Dach-Eya transcriptional effects in precursor cell proliferation and survival in mammalian organogenesis [].EYA3 forms a complex with Six1 and Ski that regulates muscle terminal differentiation [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Zhang H
Year: 2009
Journal: J Biol Chem
Title: Ski regulates muscle terminal differentiation by transcriptional activation of Myog in a complex with Six1 and Eya3.
Volume: 284
Issue: 5
Pages: 2867-79
Publication
First Author: Cook PJ
Year: 2009
Journal: Nature
Title: Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.
Volume: 458
Issue: 7238
Pages: 591-6
Publication
First Author: Borsani G
Year: 1999
Journal: Hum Mol Genet
Title: EYA4, a novel vertebrate gene related to Drosophila eyes absent.
Volume: 8
Issue: 1
Pages: 11-23
Publication
First Author: Li X
Year: 2003
Journal: Nature
Title: Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.
Volume: 426
Issue: 6964
Pages: 247-54
Publication  
First Author: Söker T
Year: 2008
Journal: BMC Dev Biol
Title: Pleiotropic effects in Eya3 knockout mice.
Volume: 8
Pages: 118
Publication
First Author: Wang Y
Year: 2019
Journal: Nat Commun
Title: The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension.
Volume: 10
Issue: 1
Pages: 4143
Publication
First Author: Masumoto KH
Year: 2010
Journal: Curr Biol
Title: Acute induction of Eya3 by late-night light stimulation triggers TSHβ expression in photoperiodism.
Volume: 20
Issue: 24
Pages: 2199-206
Strain
Attribute String: mutant stock, gene trap
Publication
First Author: Tootle TL
Year: 2003
Journal: Nature
Title: The transcription factor Eyes absent is a protein tyrosine phosphatase.
Volume: 426
Issue: 6964
Pages: 299-302
Protein
Organism: Mus musculus/domesticus
Length: 510  
Fragment?: false
Publication
First Author: Abdelhak S
Year: 1997
Journal: Nat Genet
Title: A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family.
Volume: 15
Issue: 2
Pages: 157-64
Protein
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 44  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: true
Publication  
First Author: Jemc J
Year: 2007
Journal: Annu Rev Biochem
Title: The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription.
Volume: 76
Pages: 513-38
Publication
First Author: Sano T
Year: 2011
Journal: FEBS Lett
Title: Characterization of the threonine-phosphatase of mouse eyes absent 3.
Volume: 585
Issue: 17
Pages: 2714-9
Publication
First Author: Zimmerman JE
Year: 1997
Journal: Genome Res
Title: Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene.
Volume: 7
Issue: 2
Pages: 128-41
Publication
First Author: Xu PX
Year: 1997
Journal: Development
Title: Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode.
Volume: 124
Issue: 1
Pages: 219-31
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:2677824
Assay Type: Northern blot
Annotation Date: 2003-10-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2677831
Age: postnatal adult
Specimen Label: S
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:2677824
Assay Type: Northern blot
Annotation Date: 2003-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2677831
Age: postnatal adult
Specimen Label: K
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6474209
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6474182
Age: postnatal adult
Image: 3
Specimen Label: kidney
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2159150
Assay Type: RT-PCR
Annotation Date: 2002-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619817
Stage: TS17
Assay Id: MGI:2159266
Age: embryonic day 10.5
Image: 1
Specimen Label: E10.5 Eye RNA
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2677824
Assay Type: Northern blot
Annotation Date: 2003-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:2677829
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3510751
Assay Type: RT-PCR
Annotation Date: 2004-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619421
Stage: TS21
Assay Id: MGI:3510817
Age: embryonic day 13.5
Image: 2
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2677824
Assay Type: Northern blot
Annotation Date: 2003-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2677831
Age: postnatal adult
Specimen Label: L
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6474209
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6474182
Age: postnatal adult
Image: 3
Specimen Label: lung
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2677824
Assay Type: Northern blot
Annotation Date: 2003-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2677831
Age: postnatal adult
Specimen Label: M
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6474209
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6474182
Age: postnatal adult
Image: 3
Specimen Label: muscle
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2677824
Assay Type: Northern blot
Annotation Date: 2003-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2677831
Age: postnatal adult
Specimen Label: H
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6474209
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6474182
Age: postnatal adult
Image: 3
Specimen Label: heart
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2677824
Assay Type: Northern blot
Annotation Date: 2003-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2677830
Age: embryonic day 7.0
Specimen Label: 7
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2677824
Assay Type: Northern blot
Annotation Date: 2003-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2677830
Age: embryonic day 11.0
Specimen Label: 11
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2677824
Assay Type: Northern blot
Annotation Date: 2003-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2677830
Age: embryonic day 15.0
Specimen Label: 15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2677824
Assay Type: Northern blot
Annotation Date: 2003-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2677830
Age: embryonic day 17.0
Specimen Label: 17
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3510837
Assay Type: Northern blot
Annotation Date: 2004-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3510847
Age: embryonic day 13.5
Image: 3
Specimen Label: Embryo
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6377505
Assay Type: Northern blot
Annotation Date: 2019-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6377512
Age: embryonic day 11.5
Image: 1
Specimen Label: Eya1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6474161
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6474171
Age: embryonic day 11.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6474161
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6474171
Age: embryonic day 11.5
Image: 2
Specimen Label: -/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6474163
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6474174
Age: embryonic day 11.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6474163
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6474174
Age: embryonic day 11.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6474164
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6474175
Age: embryonic day 11.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6474164
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6474175
Age: embryonic day 11.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6474165
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6474176
Age: embryonic day 11.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6474165
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6474176
Age: embryonic day 11.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6474209
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:6474203
Age: embryonic day 12.5
Image: 8
Specimen Label: ak E12.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6474209
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:6474203
Age: embryonic day 12.5
Image: 8
Specimen Label: WT E12.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6474209
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6474203
Age: embryonic day 9.5
Image: 8
Specimen Label: ak E9.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6474209
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6474203
Age: embryonic day 9.5
Image: 8
Specimen Label: WT E9.5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6474161
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:6474171
Age: embryonic day 15.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6474161
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:6474171
Age: embryonic day 15.5
Image: 2
Specimen Label: -/-
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6474161
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:6474171
Age: embryonic day 13.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6474161
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:6474171
Age: embryonic day 13.5
Image: 2
Specimen Label: -/-
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6474163
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:6474174
Age: embryonic day 13.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6474163
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:6474174
Age: embryonic day 13.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:6474163
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:6474174
Age: embryonic day 15.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6474163
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:6474174
Age: embryonic day 15.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:6474164
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:6474175
Age: embryonic day 13.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6474164
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:6474175
Age: embryonic day 13.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:6474164
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:6474175
Age: embryonic day 15.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6474164
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:6474175
Age: embryonic day 15.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:6474165
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:6474176
Age: embryonic day 13.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6474165
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:6474176
Age: embryonic day 13.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:6474165
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:6474176
Age: embryonic day 15.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6474165
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:6474176
Age: embryonic day 15.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:6474166
Assay Type: Northern blot
Annotation Date: 2020-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:6474177
Age: embryonic day 15.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6474166
Assay Type: Northern blot
Annotation Date: 2020-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:6474177
Age: embryonic day 15.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:2677824
Assay Type: Northern blot
Annotation Date: 2003-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2677831
Age: postnatal adult
Specimen Label: Li
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6474209
Assay Type: RT-PCR
Annotation Date: 2020-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6474182
Age: postnatal adult
Image: 3
Specimen Label: liver
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:2677824
Assay Type: Northern blot
Annotation Date: 2003-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2677831
Age: postnatal adult
Specimen Label: T
Detected: true
Specimen Num: 8