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Search results 1001 to 1062 out of 1062 for Smo

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Type Details Score
Publication
23946445 | J:204446
First Author: Tateya T
Year: 2013
Journal: Development
Title: Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea.
Volume: 140
Issue: 18
Pages: 3848-57
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Publication
20392931 | J:288984
First Author: Zahedi K
Year: 2010
Journal: Am J Physiol Cell Physiol
Title: The role of spermidine/spermine N1-acetyltransferase in endotoxin-induced acute kidney injury.
Volume: 299
Issue: 1
Pages: C164-74
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Publication
22968113 | J:188115
First Author: Chang H
Year: 2012
Journal: Dev Biol
Title: Mammary epithelial-restricted expression of activated c-src rescues the block to mammary gland morphogenesis due to the deletion of the C-terminus of Patched-1.
Volume: 370
Issue: 2
Pages: 187-97
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Publication
20858897 | J:244677
First Author: Fan Q
Year: 2010
Journal: J Biol Chem
Title: Requirement of TGFbeta signaling for SMO-mediated carcinogenesis.
Volume: 285
Issue: 47
Pages: 36570-6
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Publication
24276242 | J:216560
First Author: Rajurkar M
Year: 2014
Journal: Oncogene
Title: Distinct cellular origin and genetic requirement of Hedgehog-Gli in postnatal rhabdomyosarcoma genesis.
Volume: 33
Issue: 46
Pages: 5370-8
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Publication
37516749 | J:338829
First Author: Lee J
Year: 2023
Journal: Sci Rep
Title: Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development.
Volume: 13
Issue: 1
Pages: 12309
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Publication
21876161 | J:176447
First Author: Goodwin AC
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis.
Volume: 108
Issue: 37
Pages: 15354-9
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Publication
26685159 | J:229485
First Author: Blassberg R
Year: 2016
Journal: Hum Mol Genet
Title: Reduced cholesterol levels impair Smoothened activation in Smith-Lemli-Opitz syndrome.
Volume: 25
Issue: 4
Pages: 693-705
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Publication
29592971 | J:261450
 
First Author: Revenkova E
Year: 2018
Journal: J Cell Sci
Title: The Joubert syndrome protein ARL13B binds tubulin to maintain uniform distribution of proteins along the ciliary membrane.
Volume: 131
Issue: 9
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Publication
22550175 | J:184789
First Author: Lee MJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model.
Volume: 109
Issue: 20
Pages: 7859-64
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Publication
29126187 | J:277055
First Author: Wang X
Year: 2017
Journal: Biol Reprod
Title: Med12 regulates ovarian steroidogenesis, uterine development and maternal effects in the mammalian egg.
Volume: 97
Issue: 6
Pages: 822-834
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Publication
24994715 | J:214238
First Author: Li B
Year: 2014
Journal: Cancer Res
Title: Pyrvinium attenuates Hedgehog signaling downstream of smoothened.
Volume: 74
Issue: 17
Pages: 4811-21
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Publication
17287253 | J:118936
First Author: Moraes RC
Year: 2007
Journal: Development
Title: Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia.
Volume: 134
Issue: 6
Pages: 1231-42
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Publication
21123452 | J:168107
First Author: Dijkgraaf GJ
Year: 2011
Journal: Cancer Res
Title: Small molecule inhibition of GDC-0449 refractory smoothened mutants and downstream mechanisms of drug resistance.
Volume: 71
Issue: 2
Pages: 435-44
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Publication
24769368 | J:214670
First Author: Okolowsky N
Year: 2014
Journal: Dev Biol
Title: Oestrogen receptor-alpha regulates non-canonical Hedgehog-signalling in the mammary gland.
Volume: 391
Issue: 2
Pages: 219-29
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Publication
23446420 | J:194840
First Author: Atwood SX
Year: 2013
Journal: Nature
Title: GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.
Volume: 494
Issue: 7438
Pages: 484-8
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Publication
24973920 | J:227605
First Author: Tang Y
Year: 2014
Journal: Nat Med
Title: Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.
Volume: 20
Issue: 7
Pages: 732-40
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Publication
30982371 | J:294491
First Author: Kugler MC
Year: 2019
Journal: Exp Lung Res
Title: The Hedgehog target Gli1 is not required for bleomycin-induced lung fibrosis.
Volume: 45
Issue: 1-2
Pages: 22-29
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Publication
9811851 | J:50930
First Author: Carpenter D
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Characterization of two patched receptors for the vertebrate hedgehog protein family.
Volume: 95
Issue: 23
Pages: 13630-4
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Publication
22771375 | J:186236
First Author: Yang S
Year: 2012
Journal: Bone
Title: The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis.
Volume: 51
Issue: 3
Pages: 407-17
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Publication
12773389 | J:83760
First Author: Grachtchouk V
Year: 2003
Journal: EMBO J
Title: The magnitude of hedgehog signaling activity defines skin tumor phenotype.
Volume: 22
Issue: 11
Pages: 2741-51
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Publication
15492281 | J:93644
First Author: Athar M
Year: 2004
Journal: Cancer Res
Title: Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis.
Volume: 64
Issue: 20
Pages: 7545-52
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Publication
17440069 | J:120949
First Author: Kim Y
Year: 2007
Journal: Cancer Res
Title: Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells.
Volume: 67
Issue: 8
Pages: 3583-93
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Publication
20071678 | J:164812
First Author: Wu J
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Neuroprotective effect of upregulated sonic Hedgehog in retinal ganglion cells following chronic ocular hypertension.
Volume: 51
Issue: 6
Pages: 2986-92
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Publication
21660044 | J:178044
First Author: Mar BG
Year: 2011
Journal: Leukemia
Title: The controversial role of the Hedgehog pathway in normal and malignant hematopoiesis.
Volume: 25
Issue: 11
Pages: 1665-73
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Publication
24498290 | J:212851
First Author: Meng Q
Year: 2014
Journal: PLoS One
Title: Expression of signaling components in embryonic eyelid epithelium.
Volume: 9
Issue: 2
Pages: e87038
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Publication
24816261 | J:213120
First Author: Carbe CJ
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Gi proteins mediate activation of the canonical hedgehog pathway in the myocardium.
Volume: 307
Issue: 1
Pages: H66-72
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Publication
25172843 | J:216693
First Author: Athar M
Year: 2014
Journal: Cancer Res
Title: Sonic hedgehog signaling in Basal cell nevus syndrome.
Volume: 74
Issue: 18
Pages: 4967-75
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Publication
26545965 | J:227120
First Author: Kharebava G
Year: 2015
Journal: Biol Open
Title: N-docosahexaenoylethanolamine regulates Hedgehog signaling and promotes growth of cortical axons.
Volume: 4
Issue: 12
Pages: 1660-70
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Publication
25523141 | J:255222
First Author: Kwon IK
Year: 2015
Journal: Biochim Biophys Acta
Title: Mitochondrial function contributes to oxysterol-induced osteogenic differentiation in mouse embryonic stem cells.
Volume: 1853
Issue: 3
Pages: 561-72
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Publication
29531057 | J:261086
First Author: Tan IL
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation.
Volume: 115
Issue: 13
Pages: 3392-3397
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Publication
29802197 | J:267088
First Author: Cheng L
Year: 2018
Journal: J Biol Chem
Title: Coupling of Smoothened to inhibitory G proteins reduces voltage-gated K+ currents in cardiomyocytes and prolongs cardiac action potential duration.
Volume: 293
Issue: 28
Pages: 11022-11032
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Publication
30193893 | J:276001
 
First Author: Woods S
Year: 2019
Journal: Matrix Biol
Title: miR-324-5p is up regulated in end-stage osteoarthritis and regulates Indian Hedgehog signalling by differing mechanisms in human and mouse.
Volume: 77
Pages: 87-100
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Publication
28276480 | J:316019
 
First Author: Coni S
Year: 2017
Journal: Sci Rep
Title: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.
Volume: 7
Pages: 44079
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Publication
29438014 | J:330076
 
First Author: Pusapati GV
Year: 2018
Journal: Sci Signal
Title: G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.
Volume: 11
Issue: 516
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Publication
34870341 | J:344039
First Author: Zhang L
Year: 2022
Journal: J Bone Miner Res
Title: Hedgehog Signaling Controls Bone Homeostasis by Regulating Osteogenic/Adipogenic Fate of Skeletal Stem/Progenitor Cells in Mice.
Volume: 37
Issue: 3
Pages: 559-576
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Publication
35421365 | J:325181
First Author: Saeki N
Year: 2022
Journal: Exp Cell Res
Title: Pregnane X receptor (PXR) represses osteoblast differentiation through repression of the Hedgehog signaling pathway.
Volume: 416
Issue: 1
Pages: 113156
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Publication
36120578 | J:329294
 
First Author: Xiu C
Year: 2022
Journal: Front Cell Dev Biol
Title: Suppressor of fused-restrained Hedgehog signaling in chondrocytes is critical for epiphyseal growth plate maintenance and limb elongation in juvenile mice.
Volume: 10
Pages: 997838
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Publication
35622214 | J:329345
First Author: Morimoto Y
Year: 2022
Journal: Neurochem Res
Title: TPT1 Supports Proliferation of Neural Stem/Progenitor Cells and Brain Tumor Initiating Cells Regulated by Macrophage Migration Inhibitory Factor (MIF).
Volume: 47
Issue: 9
Pages: 2741-2756
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Publication
36227576 | J:331058
 
First Author: Xu J
Year: 2022
Journal: Development
Title: The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFβ signaling pathways to drive tongue organogenesis.
Volume: 149
Issue: 21
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Publication
24227720 | J:204171
First Author: Crowther AJ
Year: 2013
Journal: J Neurosci
Title: Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma.
Volume: 33
Issue: 46
Pages: 18098-108
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Publication
21356043 | J:177234
 
First Author: Blair HJ
Year: 2011
Journal: BMC Biol
Title: Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus.
Volume: 9
Pages: 14
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Publication
33028094 | J:318636
First Author: Chapouly C
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes).
Volume: 40
Issue: 12
Pages: e336-e349
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Publication
28233033 | J:241519
First Author: Braune J
Year: 2017
Journal: Diabetologia
Title: Hedgehog signalling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism.
Volume: 60
Issue: 5
Pages: 889-899
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Publication
29969579 | J:263790
 
First Author: Franco A
Year: 2018
Journal: J Mol Cell Cardiol
Title: G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts.
Volume: 121
Pages: 60-68
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Publication
28734986 | J:257902
 
First Author: Liu X
Year: 2017
Journal: Bone
Title: Exogenous hedgehog antagonist delays but does not prevent fracture healing in young mice.
Volume: 103
Pages: 241-251
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Publication
23840306 | J:203727
First Author: Cervelli M
Year: 2013
Journal: PLoS One
Title: A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to Excitotoxic Injury.
Volume: 8
Issue: 6
Pages: e64810
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Publication
35184170 | J:326294
First Author: Paudel S
Year: 2022
Journal: Carcinogenesis
Title: Chemopreventive efficacy of silibinin against basal cell carcinoma growth and progression in UVB-irradiated Ptch+/- mice.
Volume: 43
Issue: 6
Pages: 557-570
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Publication
12542834 | J:102978
First Author: Kimi K
Year: 2003
Journal: J Oral Pathol Med
Title: Immunohistochemical and genetic analysis of mandibular cysts in heterozygous ptc knockout mice.
Volume: 32
Issue: 2
Pages: 108-13
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Publication
12477380 | J:82342
First Author: Vujcic S
Year: 2003
Journal: Biochem J
Title: Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion.
Volume: 370
Issue: Pt 1
Pages: 19-28
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Publication
34210780 | J:309463
First Author: Hor CHH
Year: 2021
Journal: J Neurosci
Title: Multifaceted Functions of Rab23 on Primary Cilium-Mediated and Hedgehog Signaling-Mediated Cerebellar Granule Cell Proliferation.
Volume: 41
Issue: 32
Pages: 6850-6863
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Protein Coding Gene
MGI:1345643 | Sufu
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
26450969 | J:226691
First Author: Williams SE
Year: 2015
Journal: Development
Title: Aspm sustains postnatal cerebellar neurogenesis and medulloblastoma growth in mice.
Volume: 142
Issue: 22
Pages: 3921-32
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Publication
24107773 | J:206076
First Author: Diede SJ
Year: 2013
Journal: Epigenetics
Title: Fundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer.
Volume: 8
Issue: 12
Pages: 1254-60
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Protein
Q5MPP0
Organism: Mus musculus/domesticus
Length: 372  
Fragment?: false
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Protein Coding Gene
MGI:95727 | Gli1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
27317298 | J:236799
First Author: Zhou X
Year: 2016
Journal: Exp Neurol
Title: Effect of the sonic hedgehog receptor smoothened on the survival and function of dopaminergic neurons.
Volume: 283
Issue: Pt A
Pages: 235-45
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Publication
30653446 | J:341773
First Author: Niu C
Year: 2019
Journal: Autophagy
Title: Metformin alleviates hyperglycemia-induced endothelial impairment by downregulating autophagy via the Hedgehog pathway.
Volume: 15
Issue: 5
Pages: 843-870
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Publication
19076778 | J:173443
First Author: Huse JT
Year: 2009
Journal: Brain Pathol
Title: Genetically engineered mouse models of brain cancer and the promise of preclinical testing.
Volume: 19
Issue: 1
Pages: 132-43
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Protein Coding Gene
MGI:95728 | Gli2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95729 | Gli3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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