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Search results 1 to 100 out of 6165 for Kit

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Type Details Score
Gene
Type: gene
Organism: sheep
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: cat, domestic
Gene
Type: gene
Organism: pig, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:7275264
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-09
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7275292
Age: postnatal day 6
Image: 5A KIT
Specimen Label: 5A KIT
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5447673
Assay Type: RNA in situ
Annotation Date: 2013-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2840723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5448255
Age: embryonic day 15.5
Image: 5A Kit
Specimen Label: 5A Kit
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7275264
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-09
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7275292
Age: postnatal adult
Image: 6A KIT
Specimen Label: 6A KIT
Detected: true
Specimen Num: 3
Gene
Type: gene
Organism: human
GXD Expression
Probe: MGI:7275264
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-09
Strength: Present
Sex: Male
Emaps: EMAPS:3148228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7275292
Age: postnatal day 6
Image: 5A KIT (inset)
Note: Expression in differentiating spermatogonia.
Specimen Label: 5A KIT (inset)
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7275264
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-09
Strength: Present
Sex: Male
Emaps: EMAPS:3148228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7275292
Age: postnatal adult
Image: 6A KIT (inset)
Note: Expression in differentiating spermatogonia.
Specimen Label: 6A KIT (inset)
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:7275264
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-09
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7275292
Age: postnatal day 6
Image: 5A KIT (inset)
Note: Expression in differentiating spermatogonia.
Specimen Label: 5A KIT (inset)
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7275264
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-09
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7275292
Age: postnatal adult
Image: 6A KIT (inset)
Note: Expression in differentiating spermatogonia.
Specimen Label: 6A KIT (inset)
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:5811420
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5823653
Age: embryonic day 11.5
Image: S1A - Kit - E11.5
Note: Staining is observed in multiple domains.
Specimen Label: S1A - Kit - E11.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5811420
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5823653
Age: embryonic day 10.5
Image: S1A - Kit - E10.5
Note: Staining is observed in multiple domains.
Specimen Label: S1A - Kit - E10.5
Detected: true
Specimen Num: 1
Publication
First Author: Rothschild G
Year: 2003
Journal: Biol Reprod
Title: A role for kit receptor signaling in Leydig cell steroidogenesis.
Volume: 69
Issue: 3
Pages: 925-32
Publication
First Author: Huang EJ
Year: 1992
Journal: Mol Biol Cell
Title: Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2.
Volume: 3
Issue: 3
Pages: 349-62
GXD Expression    
Probe: MGI:4938620
Assay Type: RT-PCR
Annotation Date: 2011-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:4938618
Age: embryonic day 11.5
Image: 5
Specimen Label: Kit +/+
Detected: true
Specimen Num: 1
Publication
First Author: Berrozpe G
Year: 1999
Journal: Blood
Title: The W(sh), W(57), and Ph Kit expression mutations define tissue-specific control elements located between -23 and -154 kb upstream of Kit.
Volume: 94
Issue: 8
Pages: 2658-66
Publication
First Author: Ye L
Year: 2012
Journal: PLoS One
Title: Aging Kit mutant mice develop cardiomyopathy.
Volume: 7
Issue: 3
Pages: e33407
Publication
First Author: Thorén LA
Year: 2008
Journal: J Immunol
Title: Kit regulates maintenance of quiescent hematopoietic stem cells.
Volume: 180
Issue: 4
Pages: 2045-53
Publication      
First Author: Sweet H
Year: 2002
Journal: MGI Direct Data Submission
Title: New allele of the Kit series, KitW-82J
Publication
First Author: Grimbaldeston MA
Year: 2005
Journal: Am J Pathol
Title: Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo.
Volume: 167
Issue: 3
Pages: 835-48
Publication
First Author: Li H
Year: 2011
Journal: J Immunol
Title: Kit (W-sh) mice develop earlier and more severe experimental autoimmune encephalomyelitis due to absence of immune suppression.
Volume: 187
Issue: 1
Pages: 274-82
Publication
First Author: Guerif F
Year: 2002
Journal: Int J Androl
Title: Characterization of the fertility of Kit haplodeficient male mice.
Volume: 25
Issue: 6
Pages: 358-68
Publication
First Author: Cohen NA
Year: 2015
Journal: Cancer Res
Title: Pharmacological Inhibition of KIT Activates MET Signaling in Gastrointestinal Stromal Tumors.
Volume: 75
Issue: 10
Pages: 2061-70
Publication
First Author: John GB
Year: 2009
Journal: Dev Biol
Title: Kit signaling via PI3K promotes ovarian follicle maturation but is dispensable for primordial follicle activation.
Volume: 331
Issue: 2
Pages: 292-9
Publication
First Author: Minei R
Year: 2023
Journal: Sci Rep
Title: Compensatory gene expression potentially rescues impaired brain development in Kit mutant mice.
Volume: 13
Issue: 1
Pages: 4166
Publication    
First Author: Zaman T
Year: 2024
Journal: Elife
Title: Kit Ligand and Kit receptor tyrosine kinase sustain synaptic inhibition of Purkinje cells.
Volume: 12
Publication  
First Author: Magnol L
Year: 2007
Journal: BMC Dev Biol
Title: KIT is required for hepatic function during mouse post-natal development.
Volume: 7
Pages: 81
Publication
First Author: Rossi F
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor.
Volume: 103
Issue: 34
Pages: 12843-8
Publication
First Author: Larue L
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Spontaneous malignant transformation of melanocytes explanted from Wf/Wf mice with a Kit kinase-domain mutation.
Volume: 89
Issue: 16
Pages: 7816-20
Publication  
First Author: Fantin A
Year: 2021
Journal: Front Cell Dev Biol
Title: KIT Is Required for Fetal Liver Hematopoiesis.
Volume: 9
Pages: 648630
Publication  
First Author: Luan Y
Year: 2024
Journal: EBioMedicine
Title: KIT in oocytes: a key factor for oocyte survival and reproductive lifespan.
Volume: 106
Pages: 105263
Publication
First Author: Lacombe J
Year: 2013
Journal: Blood
Title: Genetic interaction between Kit and Scl.
Volume: 122
Issue: 7
Pages: 1150-61
Publication      
First Author: Du X
Year: 2008
Journal: MGI Direct Data Submission
Title: Pretty2 is an allele of Kit and displays pigmentation defects
GXD Expression  
Probe: MGI:4427880
Assay Type: RNA in situ
Annotation Date: 2011-02-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4938301
Age: embryonic day 14.5
Note: Expression is present in single cells in which the intercellular distance between stained cells is approximately equal to the cell diameter of an individual cell. A thumbnail photo of the staining is contained in the table.
Specimen Label: Table S9 - Kit
Detected: true
Specimen Num: 1
Publication
First Author: Kissel H
Year: 2000
Journal: EMBO J
Title: Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses.
Volume: 19
Issue: 6
Pages: 1312-26
Publication
First Author: Rubin BP
Year: 2005
Journal: Cancer Res
Title: A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E.
Volume: 65
Issue: 15
Pages: 6631-9
Publication
First Author: Flanagan JG
Year: 1991
Journal: Cell
Title: Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant.
Volume: 64
Issue: 5
Pages: 1025-35
Publication
First Author: Aoki H
Year: 2011
Journal: J Invest Dermatol
Title: Protective effect of Kit signaling for melanocyte stem cells against radiation-induced genotoxic stress.
Volume: 131
Issue: 9
Pages: 1906-15
Publication      
First Author: Tacconi C
Year: 2022
Journal: Angiogenesis
Title: KIT is dispensable for physiological organ vascularisation in the embryo.
Publication
First Author: Huang Z
Year: 2014
Journal: Am J Pathol
Title: Mutation in the first Ig-like domain of Kit leads to JAK2 activation and myeloproliferation in mice.
Volume: 184
Issue: 1
Pages: 122-32
Publication
First Author: Aoki H
Year: 2005
Journal: Dev Dyn
Title: Cooperative and indispensable roles of endothelin 3 and KIT signalings in melanocyte development.
Volume: 233
Issue: 2
Pages: 407-17
Publication
First Author: Guerif F
Year: 2002
Journal: Biol Reprod
Title: Apoptosis, onset and maintenance of spermatogenesis: evidence for the involvement of Kit in Kit-haplodeficient mice.
Volume: 67
Issue: 1
Pages: 70-9
Publication
First Author: Sharma Y
Year: 2007
Journal: Exp Hematol
Title: Heterozygous kit mutants with little or no apparent anemia exhibit large defects in overall hematopoietic stem cell function.
Volume: 35
Issue: 2
Pages: 214-220
Publication
First Author: Reith AD
Year: 1991
Journal: EMBO J
Title: Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase.
Volume: 10
Issue: 9
Pages: 2451-9
Publication
First Author: Wu B
Year: 2009
Journal: Current Zoology
Title: Homozygous lethality and heterozygous spotting due to a novel missense mutation in the mouse Kit gene.
Volume: 55
Issue: 6
Pages: 430-434
Publication
First Author: Lourenssen S
Year: 2000
Journal: Neuroreport
Title: Defects in sensory nerve numbers and growth in mutant Kit and Steel mice.
Volume: 11
Issue: 6
Pages: 1159-65
Publication
First Author: Rossi P
Year: 1992
Journal: Dev Biol
Title: A novel c-kit transcript, potentially encoding a truncated receptor, originates within a kit gene intron in mouse spermatids.
Volume: 152
Issue: 1
Pages: 203-7
Publication
First Author: Deshpande S
Year: 2013
Journal: Stem Cells
Title: KIT receptor gain-of-function in hematopoiesis enhances stem cell self-renewal and promotes progenitor cell expansion.
Volume: 31
Issue: 8
Pages: 1683-95
Publication
First Author: Reynaud K
Year: 2001
Journal: Reproduction
Title: Alterations in ovarian function of mice with reduced amounts of KIT receptor.
Volume: 121
Issue: 2
Pages: 229-37
Publication
First Author: Mackenzie MA
Year: 1997
Journal: Dev Biol
Title: Activation of the receptor tyrosine kinase Kit is required for the proliferation of melanoblasts in the mouse embryo.
Volume: 192
Issue: 1
Pages: 99-107
Publication
First Author: Hou L
Year: 2000
Journal: Development
Title: Signaling and transcriptional regulation in the neural crest-derived melanocyte lineage: interactions between KIT and MITF.
Volume: 127
Issue: 24
Pages: 5379-89
Publication
First Author: Reboll MR
Year: 2022
Journal: Science
Title: Meteorin-like promotes heart repair through endothelial KIT receptor tyrosine kinase.
Volume: 376
Issue: 6599
Pages: 1343-1347
Publication
First Author: Sommer G
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase.
Volume: 100
Issue: 11
Pages: 6706-11
Publication
First Author: Kraiger M
Year: 2022
Journal: Sci Rep
Title: Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI.
Volume: 12
Issue: 1
Pages: 14608
Publication
First Author: Cairns LA
Year: 2003
Journal: Blood
Title: Kit regulatory elements required for expression in developing hematopoietic and germ cell lineages.
Volume: 102
Issue: 12
Pages: 3954-62
Publication
First Author: Hayashi S-I
Year: 1992
Journal: ILAR News
Title: The role of Kit on murine development.
Volume: 34
Issue: 1-2
Pages: S13 (Abstr.)
Publication
First Author: Cosgun KN
Year: 2014
Journal: Cell Stem Cell
Title: Kit regulates HSC engraftment across the human-mouse species barrier.
Volume: 15
Issue: 2
Pages: 227-38
Publication
First Author: Klüppel M
Year: 1997
Journal: Development
Title: Long-range genomic rearrangements upstream of Kit dysregulate the developmental pattern of Kit expression in W57 and Wbanded mice and interfere with distinct steps in melanocyte development.
Volume: 124
Issue: 1
Pages: 65-77
Publication
First Author: Tajima Y
Year: 1991
Journal: Development
Title: Biologically active kit ligand growth factor is produced by mouse Sertoli cells and is defective in SId mutant mice.
Volume: 113
Issue: 3
Pages: 1031-5
GXD Expression
Probe: MGI:6193936
Assay Type: RNA in situ
Annotation Date: 2018-08-09
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6193944
Age: postnatal adult
Image: 3D Kit +/+
Note: Expression in germ cells.
Specimen Label: 3D Kit +/+
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:6193936
Assay Type: RNA in situ
Annotation Date: 2018-08-09
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6193944
Age: postnatal adult
Image: 3D Kit w/wv
Note: Expression not detected in absence of germ cells.
Specimen Label: 3D Kit w/wv
Detected: false
Specimen Num: 14
Publication
First Author: Tan JC
Year: 1990
Journal: Science
Title: The dominant W42 spotting phenotype results from a missense mutation in the c-kit receptor kinase.
Volume: 247
Issue: 4939
Pages: 209-12
Publication
First Author: Wu BJ
Year: 2010
Journal: Hereditas
Title: A mutation in the Kit gene leads to novel gonadal phenotypes in both heterozygous and homozygous mice.
Volume: 147
Issue: 2
Pages: 62-9
Publication
First Author: Stephenson DA
Year: 1998
Journal: Genet Res
Title: Analysis of the Kit and Pdgfra genes in the patch-extended (Phe) mutation.
Volume: 72
Issue: 3
Pages: 205-10
Publication
First Author: Filipponi D
Year: 2007
Journal: Mol Cell Biol
Title: Repression of kit expression by Plzf in germ cells.
Volume: 27
Issue: 19
Pages: 6770-81
Publication
First Author: Beckett EA
Year: 2007
Journal: Dev Dyn
Title: Kit signaling is essential for development and maintenance of interstitial cells of Cajal and electrical rhythmicity in the embryonic gastrointestinal tract.
Volume: 236
Issue: 1
Pages: 60-72
Publication
First Author: Waskow C
Year: 2007
Journal: Blood
Title: Kit is essential for PMA-inflammation-induced mast-cell accumulation in the skin.
Volume: 109
Issue: 12
Pages: 5363-70
Publication
First Author: Huang E
Year: 1990
Journal: Cell
Title: The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus.
Volume: 63
Issue: 1
Pages: 225-33
Publication
First Author: Williams DE
Year: 1990
Journal: Cell
Title: Identification of a ligand for the c-kit proto-oncogene.
Volume: 63
Issue: 1
Pages: 167-74
GO Term
Publication
First Author: Serve H
Year: 1995
Journal: EMBO J
Title: Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells.
Volume: 14
Issue: 3
Pages: 473-83
Publication  
First Author: Weidemann RR
Year: 2017
Journal: Exp Hematol
Title: Constitutive Kit activity triggers B-cell acute lymphoblastic leukemia-like disease in mice.
Volume: 45
Pages: 45-55.e6
Publication
First Author: Hayashi Y
Year: 2015
Journal: Gastroenterology
Title: Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1.
Volume: 149
Issue: 2
Pages: 420-32.e16
Publication
First Author: Aoki H
Year: 2015
Journal: J Invest Dermatol
Title: Conditional Deletion of Kit in Melanocytes: White Spotting Phenotype Is Cell Autonomous.
Volume: 135
Issue: 7
Pages: 1829-1838
Publication
First Author: Chappaz S
Year: 2010
Journal: J Immunol
Title: Kit ligand and Il7 differentially regulate Peyer's patch and lymph node development.
Volume: 185
Issue: 6
Pages: 3514-9
Publication
First Author: Kimura Y
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineages.
Volume: 101
Issue: 16
Pages: 6015-20
Publication
First Author: Ran L
Year: 2015
Journal: Cancer Discov
Title: Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth.
Volume: 5
Issue: 3
Pages: 304-15
Publication
First Author: Roskoski R Jr
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Structure and regulation of Kit protein-tyrosine kinase--the stem cell factor receptor.
Volume: 338
Issue: 3
Pages: 1307-15
Publication
First Author: Hong L
Year: 2008
Journal: Cell Signal
Title: KIT associated intracellular tyrosines play an essential role in EpoR co-signaling.
Volume: 20
Issue: 8
Pages: 1513-20
Publication
First Author: Shields BJ
Year: 2015
Journal: Leukemia
Title: Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2-transgenic mice.
Volume: 29
Issue: 4
Pages: 927-38
Publication
First Author: Jahn T
Year: 2007
Journal: Blood
Title: Lipid rafts are required for Kit survival and proliferation signals.
Volume: 110
Issue: 6
Pages: 1739-47
Publication
First Author: Gutierrez DA
Year: 2015
Journal: Cell Metab
Title: Hematopoietic Kit Deficiency, rather than Lack of Mast Cells, Protects Mice from Obesity and Insulin Resistance.
Volume: 21
Issue: 5
Pages: 678-91
Publication
First Author: Fleischman RA
Year: 1993
Journal: Trends Genet
Title: From white spots to stem cells: the role of the Kit receptor in mammalian development.
Volume: 9
Issue: 8
Pages: 285-90
Publication
First Author: Buono M
Year: 2016
Journal: Nat Cell Biol
Title: A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors.
Volume: 18
Issue: 2
Pages: 157-67
Publication
First Author: Drube S
Year: 2010
Journal: Blood
Title: The receptor tyrosine kinase c-Kit controls IL-33 receptor signaling in mast cells.
Volume: 115
Issue: 19
Pages: 3899-906
Publication  
First Author: Azzoni E
Year: 2018
Journal: EMBO Rep
Title: Kit ligand has a critical role in mouse yolk sac and aorta-gonad-mesonephros hematopoiesis.
Volume: 19
Issue: 10
Publication
First Author: Jelacic T
Year: 2005
Journal: Blood
Title: PKCdelta plays opposite roles in growth mediated by wild-type Kit and an oncogenic Kit mutant.
Volume: 105
Issue: 5
Pages: 1923-9
GXD Expression    
Probe: MGI:6176018
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190676
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Kit
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6176018
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190676
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Kit
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6176018
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190676
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Kit
Detected: true
Specimen Num: 4