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Search results 201 to 300 out of 358 for Hfe

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Type Details Score
GXD Expression  
Probe: MGI:4424642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825366
Age: embryonic day 14.5
Image: euxassay_011736_14
Specimen Label: euxassay_011736_14
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4424642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825366
Age: embryonic day 14.5
Image: euxassay_011736_15
Specimen Label: euxassay_011736_15
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4424642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825366
Age: embryonic day 14.5
Image: euxassay_011736_16
Specimen Label: euxassay_011736_16
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4424642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825366
Age: embryonic day 14.5
Image: euxassay_011736_17
Specimen Label: euxassay_011736_17
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4424642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825366
Age: embryonic day 14.5
Image: euxassay_011736_09
Specimen Label: euxassay_011736_09
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4424642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825366
Age: embryonic day 14.5
Image: euxassay_011736_05
Specimen Label: euxassay_011736_05
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4424642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825366
Age: embryonic day 14.5
Image: euxassay_011736_06
Specimen Label: euxassay_011736_06
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4424642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825366
Age: embryonic day 14.5
Image: euxassay_011736_07
Specimen Label: euxassay_011736_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4424642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825366
Age: embryonic day 14.5
Image: euxassay_011736_12
Specimen Label: euxassay_011736_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4424642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825366
Age: embryonic day 14.5
Image: euxassay_011736_13
Specimen Label: euxassay_011736_13
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4424642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825366
Age: embryonic day 14.5
Image: euxassay_011736_14
Specimen Label: euxassay_011736_14
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4424642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825366
Age: embryonic day 14.5
Image: euxassay_011736_15
Specimen Label: euxassay_011736_15
Detected: true
Specimen Num: 13
Publication
First Author: Smith KA
Year: 2006
Journal: FEBS Lett
Title: Circulating gastrin is increased in hemochromatosis.
Volume: 580
Issue: 26
Pages: 6195-8
Publication
First Author: Ludwiczek S
Year: 2007
Journal: Nat Med
Title: Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1.
Volume: 13
Issue: 4
Pages: 448-54
Publication
First Author: Jenkitkasemwong S
Year: 2015
Journal: Cell Metab
Title: SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis.
Volume: 22
Issue: 1
Pages: 138-50
Publication
First Author: Franklin MR
Year: 2002
Journal: Hepatology
Title: Uroporphyria in the uroporphyrinogen decarboxylase-deficient mouse: Interplay with siderosis and polychlorinated biphenyl exposure.
Volume: 36
Issue: 4 Pt 1
Pages: 805-11
Publication
First Author: Neves JV
Year: 2010
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hemochromatosis and pregnancy: iron stores in the Hfe-/- mouse are not reduced by multiple pregnancies.
Volume: 298
Issue: 4
Pages: G525-9
Publication
First Author: Simpson RJ
Year: 1997
Journal: Clin Sci (Lond)
Title: Time-course of iron overload and biochemical, histopathological and ultrastructural evidence of pancreatic damage in hypotransferrinaemic mice.
Volume: 93
Issue: 5
Pages: 453-62
Publication  
First Author: Ledesma-Colunga MG
Year: 2020
Journal: Bone
Title: Disruption of the hepcidin/ferroportin regulatory circuitry causes low axial bone mass in mice.
Volume: 137
Pages: 115400
Publication  
First Author: Bettencourt C
Year: 2016
Journal: Neurobiol Dis
Title: Gene co-expression networks shed light into diseases of brain iron accumulation.
Volume: 87
Pages: 59-68
Publication
First Author: Subramaniam VN
Year: 2012
Journal: Am J Pathol
Title: Hepatic iron deposition does not predict extrahepatic iron loading in mouse models of hereditary hemochromatosis.
Volume: 181
Issue: 4
Pages: 1173-9
Publication
First Author: Ali MK
Year: 2020
Journal: J Pathol
Title: Critical role for iron accumulation in the pathogenesis of fibrotic lung disease.
Volume: 251
Issue: 1
Pages: 49-62
Publication
First Author: Vaugier C
Year: 2017
Journal: J Am Soc Nephrol
Title: Serum Iron Protects from Renal Postischemic Injury.
Volume: 28
Issue: 12
Pages: 3605-3615
Publication
First Author: Huang J
Year: 2007
Journal: J Biol Chem
Title: Increased glucose disposal and AMP-dependent kinase signaling in a mouse model of hemochromatosis.
Volume: 282
Issue: 52
Pages: 37501-7
Publication  
First Author: Barasch J
Year: 2016
Journal: Nat Commun
Title: Disposal of iron by a mutant form of lipocalin 2.
Volume: 7
Pages: 12973
Publication
First Author: Wilkins SJ
Year: 2006
Journal: Blood
Title: Iron metabolism in the hemoglobin-deficit mouse: correlation of diferric transferrin with hepcidin expression.
Volume: 107
Issue: 4
Pages: 1659-64
Publication  
First Author: Hale AT
Year: 2020
Journal: Adv Biol Regul
Title: Modulation of sulfur assimilation metabolic toxicity overcomes anemia and hemochromatosis in mice.
Volume: 76
Pages: 100694
Publication
First Author: Chiou B
Year: 2020
Journal: J Neurochem
Title: Transferrin and H-ferritin involvement in brain iron acquisition during postnatal development: impact of sex and genotype.
Volume: 152
Issue: 3
Pages: 381-396
Publication
First Author: Sivaprakasam S
Year: 2020
Journal: Biochem J
Title: Hereditary hemochromatosis promotes colitis and colon cancer and causes bacterial dysbiosis in mice.
Volume: 477
Issue: 19
Pages: 3867-3883
Publication
First Author: Gnana-Prakasam JP
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis.
Volume: 52
Issue: 12
Pages: 9279-86
Publication
First Author: Guo S
Year: 2013
Journal: J Clin Invest
Title: Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice.
Volume: 123
Issue: 4
Pages: 1531-41
Publication
First Author: Robb A
Year: 2004
Journal: Blood
Title: Regulation of transferrin receptor 2 protein levels by transferrin.
Volume: 104
Issue: 13
Pages: 4294-9
Publication
First Author: Gabrielsen JS
Year: 2012
Journal: J Clin Invest
Title: Adipocyte iron regulates adiponectin and insulin sensitivity.
Volume: 122
Issue: 10
Pages: 3529-40
Publication
First Author: Gao Y
Year: 2015
Journal: J Clin Invest
Title: Adipocyte iron regulates leptin and food intake.
Volume: 125
Issue: 9
Pages: 3681-91
Publication
First Author: Pasricha SR
Year: 2017
Journal: Nat Commun
Title: Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.
Volume: 8
Issue: 1
Pages: 403
Publication
First Author: Ristic B
Year: 2020
Journal: Biochem J
Title: Hereditary hemochromatosis disrupts uric acid homeostasis and causes hyperuricemia via altered expression/activity of xanthine oxidase and ABCG2.
Volume: 477
Issue: 8
Pages: 1499-1513
Publication
First Author: De Domenico I
Year: 2010
Journal: J Clin Invest
Title: Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice.
Volume: 120
Issue: 7
Pages: 2395-405
Publication
First Author: Vujić Spasić M
Year: 2013
Journal: Biochim Biophys Acta
Title: Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload.
Volume: 1832
Issue: 1
Pages: 76-84
Publication
First Author: Arkell RM
Year: 2001
Journal: Mamm Genome
Title: Genetic, physical, and phenotypic characterization of the Del(13)Svea36H mouse.
Volume: 12
Issue: 9
Pages: 687-94
Publication
First Author: Lee P
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Regulation of hepcidin transcription by interleukin-1 and interleukin-6.
Volume: 102
Issue: 6
Pages: 1906-10
Publication
First Author: Hughes AL
Year: 1999
Journal: Immunol Today
Title: A new taxonomy of mammalian MHC class I molecules.
Volume: 20
Issue: 1
Pages: 22-6
Publication
First Author: Aksu S
Year: 2007
Journal: J Appl Genet
Title: Differentially expressed genes in adipose tissues of high body weight-selected (obese) and unselected (lean) mouse lines.
Volume: 48
Issue: 2
Pages: 133-43
Publication
First Author: Wilkin RJ
Year: 2016
Journal: Am J Pathol
Title: Murine Models of Acute Alcoholic Hepatitis and Their Relevance to Human Disease.
Volume: 186
Issue: 4
Pages: 748-60
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication
First Author: Lin Q
Year: 2006
Journal: Nucleic Acids Res
Title: Mutagenesis of diploid mammalian genes by gene entrapment.
Volume: 34
Issue: 20
Pages: e139
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Jones BC
Year: 2007
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Systems genetic analysis of peripheral iron parameters in the mouse.
Volume: 293
Issue: 1
Pages: R116-24
Allele  
Name: Hfe modifier 2; C57BL/6
Allele Type: QTL
Allele  
Name: Hfe modifier 2; DBA/2
Allele Type: QTL
Allele  
Name: Hfe modifier 4; C57BL/6
Allele Type: QTL
Allele  
Name: Hfe modifier 4; DBA/2
Allele Type: QTL
Allele  
Name: Hfe modifier 3; DBA/2
Allele Type: QTL
Allele  
Name: Hfe modifier 1; DBA/2
Allele Type: QTL
Allele  
Name: Hfe modifier 1; C57BL/6
Allele Type: QTL
Allele  
Name: Hfe modifier 3; C57BL/6
Allele Type: QTL
Publication
First Author: Bhatt L
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Knockdown of beta2-microglobulin perturbs the subcellular distribution of HFE and hepcidin.
Volume: 378
Issue: 4
Pages: 727-31
Publication  
First Author: Traeger L
Year: 2018
Journal: Commun Biol
Title: The hemochromatosis protein HFE signals predominantly via the BMP type I receptor ALK3 in vivo.
Volume: 1
Pages: 65
Allele
Name: homeostatic iron regulator; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Hfe/? Hfem1/Hfem1
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hfe/? Hfem1/Hfem1
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hfe/? Hfem2/Hfem2
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hfe/? Hfem2/Hfem2
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hfe/? Hfem3/Hfem3
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hfe/? Hfem4/Hfem4
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hfe/? Hfem4/Hfem4
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
Allele
Name: homeostatic iron regulator; targeted mutation 1, Susan Gilfillan
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: homeostatic iron regulator; targeted mutation 1.1, Wolfgang Stremmel
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: homeostatic iron regulator; targeted mutation 1.1, Nancy C Andrews
Allele Type: Targeted
Attribute String: Humanized sequence, Hypomorph
Allele
Name: homeostatic iron regulator; targeted mutation 1, William S Sly
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: homeostatic iron regulator; targeted mutation 1, Wolfgang Stremmel
Allele Type: Targeted
Attribute String: Conditional ready, No functional change